Cross-sectional study of General Health Questionnaire among a University Students in Malaysia: A Reliability Study. By Dr. Prashanth Talwar1 and Prof. Mohd Fadzil Abdul Rahman2 Dr. Prashanth Talwar1Ph.D Associate Professor Universiti Malaysia Sarawak 94300 Kota Samrahan. talpra@rediffmail.com Prof. Mohd Fadzil Abdul Rahman2 MA Professor and Deputy Vice Chancellor Universiti Malaysia Sarawak 94300 Kota Samrahan. Corresponding Author Dr. Prashanth Talwar1Ph.D Associate Professor Universiti Malaysia Sarawak 94300 Kota Samrahan. talpra@rediffmail.com Statistical summary of the manuscript Total Number of words: 3984 Number of words in abstract: 161 Number of references: 32 Number of Tables: 1 Cross-sectional study of General Health Questionnaire among a University Students in Malaysia: A Reliability Study. Abstract Background: The General Health Questionnaire is a widely used scale to measure psychological distress. This scale is available in many languages. The original version comprised of 60 items. It is available in 30-items, 28-items, 20-items and 12-items. The shorter version is as good as the longer version of the scale. Objective: The aim of this investigation was to examine the psychometric properties and reliability of the 12-item General Health Questionnaire (GHQ-12) among university students. Method: The study was conducted in one of universities in Malaysia. A total of 280 students were selected using convenient sampling. Result: The results of this study showed that the GHQ-12 is multidimensional and contains three factor structures. It has a high internal consistency and a useful instrument to measure the psychological wellbeing of university students in Malaysia. Conclusion: Although several studies have been conducted across the globe on the GHQ-12, debate surrounds in relation to its dimensionality, negative and positive wordings and cut off point. Key Words: GHQ Factor Structure Alpha Reliability. 1 Cross-sectional study of General Health Questionnaire among a University Students in Malaysia: A Reliability Study. Introduction: It goes without saying that life in the university is stressful. Stress arises due to a variety of factors such as social adjustment to the environment, assignments, peer relationship, peer pressure to achieve a high score in exams. The ability to adjust to stress depends on the individual coping strategies. Over exposure to stress can cause physical, emotional and mental health problems 1. In study done by Zaid et al 2 in Malaysia, it was found that the prevalence of emotional disorders among students was high. Zaid et al 2 reported that there was significant association between emotional disorders and respondents' relationship with their parents, siblings and lecturers, as well as level of pressure prior to exam. It is important to detect emotional disorders at an early stage so that treatment necessary can be given to those affected 2. Psychological distress can be measured using standardized instruments, which can help in detecting cases who have psychological distress. The General Health Questionnaire (GHQ12) is a self-reporting measure. This scale focuses on breaks in normal functioning rather than on life-long traits; therefore, it only covers disorders or patterns of adjustment associated with distress 4. The original version is composed of 60 items. In recent years the 12-item General Health Questionnaire (GHQ-12) has been extensively used as a short screening instrument, producing results that are comparable to longer versions of the GHQ 5. The GHQ12 is a measure of current mental health. It focuses on two major areas- inability to carry out normal functions and the appearance of new and distressing experiences 4. The 12-item General Health Questionnaire (GHQ-12) has been widely used in many countries for detecting psychological morbidity 6. It has been translated and validated in various languages 5. The GHQ-12 is also available in Malay language where the internal consistency was excellent 7. A high degree of internal consistency was observed for each of the 12 items in the Malay version 8. If investigators wish to use a screening instrument as a case detector, the shorter GHQ is remarkably robust and works as well as the longer instrument. The latter should only be preferred if there is an interest in the scaled scores provided in addition to the total score5. The GHQ threshold is partly determined by the prevalence of multiple diagnoses, with higher thresholds being associated by higher rates of both single and multiple diagnoses. The mean GHQ score for the whole population of respondents provides a rough guide to the best threshold 9. The GHQ-12 was designed as a uni-dimensional scale with positively phrased and negatively phrased items. Many factor-analytic studies have reported that the GHQ-12 has two or three dimensions, threatening its validity 10. Reviewing past research which indicates that the GHQ-12 is a brief and easy to understand screening instrument it was intended to investigation the psychometric properties of the General Health Questionnaire (GHQ-12) among university students. The aim of this 2 investigation was to examine the psychometric properties and reliability of the 12-item General Health Questionnaire (GHQ-12) among university students. Materials and Methods Participants The study was conducted in one of the universities in Malaysia. Please be specific which university? The study participants were selected using convenience sampling. The questionnaire consisting of part 1 which included the demographic aspects and part 2, the General Health Questionnaire (GHQ-12). Permission was obtained from the university before conducting this study. Undergraduate students were told about the purpose of the study and only those volunteered to participate were given the self-administered questionnaire in the class room. Data was collected from 300 students. Seven percent% of the questionnaire had to be excluded due to incomplete information. The data obtained from 280 students was taken up for final data analysis. Instrument Goldberg’s General Health Questionnaire (GHQ-12) with 12 items has four responses. The GHQ-12 can be classified as either positively worded or negatively worded. Six items referred to health is considered to be positively worded. The response range from ‘more than usual’ to ‘much less than usual’. 6 items referring to disease are negatively worded. The response ranges from ‘not at all’ to ‘much more than usual’. Items can be scores according to the three scoring methods. Likert method (all items coded 0-1-2-3), GHQ method (all items coded 0-0-1-1), and C-GHQ method (PP items coded 0-0-1-1; NP items coded 0-1-1-1). In this study, the Likert method of scoring (0-1-2-3) was chosen. The scores were summed up by adding all the items on the scale ranging from 0 to 12. Due to the various thresholds of the GHQ-12, the mean GHQ score for a population of respondents was suggested as a rough indicator for the best cut-off point 9. Based on the mean score from the study the cut-off point 12 was used. The least one can score is 0 and the maximum one can score is 36. Statistical analysis SPSS 21 was used to process the data. Descriptive analysis was done to study the frequency of students who with least score and highest score. Dimensionality was assessed using factor analysis. Exploratory factor analysis (EFA) was done using the principle component analysis. In this study the variance explained by the factor structure of the GHQ-12 for one-factor, two-factor and three-factor solutions was assessed. Rotation method used was Varimax with Kaiser Normalization. Factor loading was based on absolute value greater than 0.40. Cronbach’s11alpha coefficient was used to calculate the reliability of the scale. Cronbach's alpha is an index of reliability associated with the variation accounted for by the true score of the "underlying construct." Construct is the hypothetical variable that is being measured 12. The higher the score, the more reliable the generated scale is. Nunnaly 13 has indicated 0.7 to be an acceptable reliability coefficient. Results The mean age of the respondents was 21 years. 34 % were male and 66% were female student respondents. The mean GHQ-12 score was 12.32 (SD=5.23). The least one has scored was 3 and maximum score was 23. Taking 12 to be the cut-off point about 53% of the respondents scored more than or equal to 12. 3 Factor Structure KMO value is 0.813, which is considered meritorious. Results of Bartlett’s test of sphericity shows 2=1163.07 (df=66, p<0.000). In this study, the sample inter correlation matrix did not come from a population in which the inter correlation matrix is an identical matrix. There was no correlation error among the variables. Based on eigen value more than 1, results from EFA revealed three dimensional structures. The first factor includes items 3,4,5,6,8 and 9 and explains 22.65 % variance. The second factor includes items 7, 10, 11 and 12 and explains 19.84 % variance. The third factor includes two items 1 and 2 and explains 16.53 % variance. Total variance explained by the three factors is 59.03 %. Reliability. The internal consistency was measured using Cronbach's alpha. The overall Cronbach's alpha for the entire sample in this study was 0.84. Alpha value for male students was 0.85 and that for the female students was 0.83 respectively. Table No. 1 shows correlation between items and Cronbach's alpha if Item were to be deleted. The overall Cronbach's alpha was 0.84. Only item no 1 “Been able to concentrate on whatever you are doing?” showed the lowest correlation coefficient of 0.32. All the remaining items showed a correlation ranging from 0.45 to 0.59. Eliminating item No. 1 did not change the value of Cronbach's alpha substantially. Table No 1 Correlation between items and Reliability analysis of GHQ-12. No. Item Corrected Cronbach's Item-Total Alpha if Correlation Item Deleted Been able to concentrate on whatever you are GHQ1 .321 .838 doing? Lost much sleep over worry? GHQ2 .527 .823 Felt that your were playing a useful part in GHQ3 .533 .823 things? Felt capable of making decisions about things? GHQ4 .456 .829 Felt constantly under strain? GHQ5 .549 .822 Felt that you could not overcome your GHQ6 .595 .818 difficulties? Been able to enjoy your normal day-to-day GHQ7 .453 .829 activities? Been able to face up your problems? GHQ8 .472 .828 Been feeling unhappy and depressed? GHQ9 .467 .828 Been losing confidence in yourself? GHQ10 .501 .825 Been thinking of yourself as a worthy person? GHQ11 .582 .819 Been feeling reasonably happy, all things GHQ12 considered? .545 .822 4 Discussion It is necessary for students to be in their good and balanced psychological health in order to excel in their pursuit and for a successful future by contributing positively towards human capital resources of the country 14. Stress among university students in Malaysia is high. In a study done by medical students in Malaysia it was found a total of 41.9% of the medical students were found to have emotional disorders 15. The GHQ-12 was used to assess the psychological wellbeing of university students. The GHQ-12 item questionnaire is the most extensive (are you sure this is the most extensive ? even as compared to long version?) used screening instrument for common mental disorders, in addition to being a more general measure of psychiatric well-being16. The aim of this investigation was to examine the psychometric properties and reliability of the 12-item General Health Questionnaire (GHQ-12) among university students. The mean GHQ-12 score was 12.32 (SD=5.23). A cut off point of 12 or higher was considered as those having problems. Taking 12 to be the cut-off point based on the mean about 53% of the respondents scored ≥12. This shows that a sizeable portion of students experienced psychological distress. The least score was 3 and maximum score was 23. Using Kaiser-Meyer Olkin test of Sphercity it was found the GHQ-12 obtained from this sample was suitable to conduct factor analysis and sample size was appropriate using the Bartlett’s test of sphericity. Agree with the statement. Different versions of the General Health Questionnaire (GHQ), including the GHQ-12 and GHQ-28 have been subjected to factor analysis in a variety of countries17. In this study, exploratory Factor analysis of GHQ-12 revealed three dimensional structures. Factor I consisted of 6 items explained 22.65 % variance. Factor II consisted of 4 items explained 19.84 % variance. Factor III consisted of 2 items explained 16.53 % variance. Total variance explained by the three factors is 59.03 %. It was found that the loadings ranged from 0.46 to 0.80. Majority of the loading was >0.50. The number of items loaded differed from one study to another. This study is similar to the study done by Sánchez-López 16 who reported a three factor model with 54.19 % explained variance. This study is also consistent with studies done in Malaysia by Zulkefly & Baharudin 14 which explained three factor structure with 51.9% variance and fits into the three factors namely psychological distress, social and emotional dysfunction and cognitive disorder, thought the items may slightly differ from one another. Unidimensional or multidimensional – The GHQ-12 was designed as a uni-dimensional scale with six items positively phrased and remaining six items negatively phrased items. Few studies have reported GHQ-12 to be uni-dimensional, other studies reported two dimensions and yet few others, three dimensional 6, 18. The factorial structure of GHQ-12 may be debatable in view of discrepancy in reported by authors. Validation studies have assumed that the GHQ-12 is one-dimensional and free of response bias, but recent evidence suggests that neither of these assumptions may be correct, threatening its utility as a screening instrument19. Like any other instruments GHQ-12 too comes with its own limitations. Three aspects of GHQ-12 is contentious, the first being the number of dimensions - which would be the best fit; the second is the cut-off point and third is the positive and negative wordings. In this study attempts are made to debate the factor structures however, to avoid lengthy discussions only two or more authors work has been cited for comparison. 5 Single Factor Model. Using the Likert-type scoring approach, Hankins's one-factor model with "method effects" obtained the best fit20. Confirmatory factor analyses showed that the one-factor structure, controlling by the wording effect, gathered the best fit indexes. It was concluded that the one-factor model of the GHQ-12 is more appropriate21. Studies done by Lesage 22 supports a single factor structure, as in the original Goldberg’s version. However, according to Gao et al 6 the one-dimensional model was the worst according to all three goodness-of-fit indices. Two Factor Model. The principal component analysis with oblique rotation solution showed that the GHQ-12 was a measure of psychological morbidity with two-factor structure, that jointly accounted for 51% of the variance23. In another study, Hu et al 24 reported that the best description of the factor structure of the GHQ-12 is given by a variant of a two-factor solution, corresponding to positive mental health and symptoms of mental disorder. Kalliath et al 25 reported that the results favour a two-factor model consisting of a ‘Social Dysfunction’ factor and an ‘Anxiety/Depression’ factor measured by four items each. Three Factor Model. The CFA of the GHQ-12 indicated that the best fit and the simplest solution were provided by the three-factor solution in both subpopulations 26. Graetz 27 examined the factor structure of the 12 item GHQ and proposed that the model with the best fit is the three factor model. Several studies have found that Graetz's 3-factor model of the GHQ-12 is more plausible than other models 28. In a study done by Padrón 29, the model with the best fit in the CFA was the three-dimensional model, social dysfunction, anxiety and self-esteem, the three factors together explained 53.7% of the variance. It is not necessary that the three factor model is the best solution. Salama-Younes et al suggests that analysis for the GHQ-12 demonstrated a good fit not only to the two-factor model (positive vs. negative items) but also to a three-factor model. Further, Padrón 29 also reported a good fit in two factor as well as three factor model. 30 In this study the variance explained by the factor structure of the GHQ-12 for one-factor, two-factor and three-factor solutions was assessed, it was found that one factor explained 36.48 % variance, two factor explained 49.47 % variance and the three factor solution explained 59.03 % variance. Therefore, it is sensible to accept the three factor model as the best solution. The overall Cronbach's Alpha for the entire sample in this study was 0.84. In a similar study done by Yusoff et al 31. Cronbach’s alpha values for the GHQ-12 was of 0.85. Thus, this study matches with study done elsewhere in Malaysia. Study also matches with studies done in Iran, where Montazeri et al 23, found Cronbach's alpha coefficient of 0.87. Alpha value for male students was 0.85 and that for the female students was 0.83 respectively. This shows a good fitting of internal consistency for both the groups. Anther debate that surrounds the GHQ-12 is the cut-off point. The cut-off point for GHQ-12 varies from one study to another. The finding of variation in the optimal threshold of the General Health Questionnaire (GHQ) across different settings has proved difficult to explain 32 . No convincing explanation has been forthcoming for the variation in best threshold to adopt for the GHQ in different settings 9. According to Godlberg et al 9, the GHQ threshold is partly determined by the prevalence of multiple diagnoses, with higher thresholds being 6 associated by higher rates of both single and multiple diagnosis. The mean GHQ score for the whole population of respondents provides a rough guide to the best threshold 9. In this study the cut-off was arrived at based on the mean. Positively worded and negatively worded items too could be a problem. According to Hankins, conventional psychometric assessments using factor analysis and reliability estimates have obscured substantial measurement error in the GHQ-12 due to response bias on the negative items, which limits its utility as a screening instrument for psychiatric morbidity 19. Hu et al 24, is of the opinion that, one weakness lies in the GHQ-12 itself. All self-report questionnaires are prone to method variance, namely the tendency for people to respond the same way to similarly worded items. This may contribute to the aggregation of responses to positively and negatively worded items. Although statistical methods exist for distinguishing between this and ‘true’ variance due to latent constructs, these methods are not applicable where there are only one or two construct factors 24. In conclusion, the GHQ-12 is a widely used scale to measure psychological health. This scale has been tested and validated in many languages. As found in this study other studies too show that this scale has a good internal consistency. There is difference of opinion regarding the factor structure of the scale as some authors say that one factor model is the best fit others do not agree with one factor model and suggest two or three factor model. Others have shown that the two factor model is as good as three factor model. 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The Malaysian Journal of Medical Sciences :2010; 17(1): 30–7. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3216143&tool=pmcentrez &rendertype 32. Willmott S A, Boardman JAP, Henshaw C A & Jones PW. Understanding General Health Questionnaire (GHQ-28) score and its threshold. Social Psychiatry and Psychiatric Epidemiology. 2004; 39(8): 613–617. The authors failed to address why there is a need to revalidate the GHQ as previous studies were conducted to look at the psychometric properties of this scale. What is the strength of this study as compared to other studies? In the result there is no validity analysis such as the analysis of factor loading, however there is a discussion on factor models. Please describe the detail of handling data missing of 20 subjects which were excluded in the study. Convenient sampling is one of the setbacks of the study which could be highlighted. Please display the demographic profiles of your subjects as the level of education and races may influence the psychometric properties of a scale. My conclusion is the manuscript is publishable with several modifications. 10