Chapter 13 Medication Orders 1 Objectives • Explain the benefits of Computer Physician Order Entry regarding medication orders. • Define standing, standing prn, stat, one-time, and short-series medication orders. • List the five components of a medication order. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 2 Objectives, continued • List four groups of drugs that usually have automatic “stop dates.” • Name two reference books for medications. • List four routes by which medications are administered. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 3 Objectives, continued • Demonstrate the procedure for using the Physicians’ Desk Reference (PDR). • Describe the general purpose for selected drug groups. • Name three common skin tests performed and explain the purpose of each. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 4 Objectives, continued • Recognize the most commonly used drugs, which are listed in italics in the “Drug Groups” section of the chapter, and name the drug group to which each belongs. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 5 Lesson 13.1 Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 6 Adverse Drug Events (ADEs) 770,000 people are injured or die annually as a result of ADEs • 56% occurred at the stage of ordering • 34% at administration • 6% at transcribing • 4% at dispensing Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 7 Computer Physician Order Entry (CPOE) & Clinical Decision Support System (CDSS) • Medications are ordered automatically when CPOE is implemented • Orders are sent directly to the pharmacy • Handwriting errors are reduced and fewer adverse drug events occur • Orders are integrated with patient information, allergies, lab results, and prescription data when used with a Clinical Decision Support System (CDSS) • Physicians are warned against drug interactions, allergies, or overdose Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 8 Medical Administration Record (MAR): Computerized or Handwritten • Medication orders are printed or written on the MAR • The MAR is a permanent part of the patient’s chart Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 9 Medication Names • Official name: name under which drug is listed in official government publications of drug standards • Chemical name: name that describes the chemical composition of the drug • Generic name: shortened name given to the drug by the developer; generic names are not capitalized Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 10 Medication Names, continued • Brand name, trade name, or proprietary name: name given to and registered by the manufacturer The brand name is always capitalized and may have a trademark symbol (™ or ®) A drug has only one generic name but may have many trade names, depending on how many companies manufacture it Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 11 5 Components of a Medication Order 1. Name of medication 2. Dose 3. Route 4. Frequency 5. Qualifying phrase Example: Demerol 100 mg IM q 4 hrs for pain (1) (2) (3) (4) (5) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 12 Medication Forms Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 13 Medication Doses • Apothecary system • Metric system Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 14 Apothecary System • Grain • Dram • Ounce gr dr or or • Measurements in this system are written in lower case Roman numerals. These numerals have a line over them and may be dotted to avoid confusion with similar-appearing letters or numerals Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 15 Metric System • Weight • Volume • Length gram (g) liter (L) meter (M) • Smaller and larger units in the metric system can be indicated by attaching prefixes to the basic units Kilo- is used to enlarge the basic unit 1000 times Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 16 Metric System, continued • centi (cm) is used to diminish the basic unit by 100 • milli (mm), (mL), and (mg) diminishes the basic unit by 1000 • The symbol µ micro (micrometer or 0.001 millimeter) • The terms milliliter (ML) and cubic centimeter (CC) are used interchangeably Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 17 Metric System, continued • The metric system uses the Arabic numerals that we all know, e.g., 1, 2, 3 • Abbreviations are placed after the number, as in 50 mg or 500 mL • Quantities less than 1 and fractions are written in decimal form as in 0.25 mg, 1.25 mg, and 1.5 g Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 18 Routes for Administering Medication • PO • Sub-ling - SL • Topical • Inhalants Oral Under the tongue Sprays, creams, suppositories Nebulizers Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 19 Routes for Administering Medication, continued Parenteral: Intramuscular (IM) Intravenous (IV) Subcutaneous (SQ) Intradermal (ID) Transdermal Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 20 Angle of Needle Insertion for Parenteral Injections From Potter PA, Perry AG: Fundamentals of Nursing, 6th ed, St. Louis, Mosby, 2005. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 21 To Reduce Needle Sticks: A Syringe with Needleless Adapter and Sharps Disposal From Potter PA, Perry AG: Fundamentals of Nursing, 6th ed, St. Louis, Mosby, 2005. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 22 Three Components of an IV Order • Amount • Solution • Rate Examples: Amt Sol Rate 1000cc D5LR TRA 120cc/hr or Amt Sol Rate 1000cc 0.45 NS TKO Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 23 IV Push and IV Bolus • IV Push: method of giving concentrated doses of medication directly into the vein • IV Bolus: concentrated dose of medication or fluid, frequently given intravenously Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 24 Admixture • The result of adding a medication to a container of intravenous fluid Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 25 Intravenous Piggyback (IVPB) • Medication is added to 50-100 cc of fluid in a small bag and connected to port in main IV tubing Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 26 Frequency of Administration • Each hospital maintains a schedule of hours for administration of medications that is set up by the hospital nursing service • You are required to learn the hours that are standard for your hospital • Note: Standard prn orders are never assigned a time, because the drugs are administered as they are needed by the patient Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 27 Qualifying Phrases • When a doctor wishes a drug to be administered only for specific conditions, a qualifying phrase will be part of the medication order • Not all orders contain qualifying phrases • Examples of commonly used phrases: For severe pain For stomach spasms For N/V While awake For insomnia Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 28 5 Rights of Medication Administration • • • • • Right drug Right dose Right time Right route Right patient Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 29 The Joint Commission’s (TJC’s) “Do Not Use” Abbreviation List Courtesy of The Joint Commission May 2005 Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 30 Categories of Medication Orders • Standing Example: Synthroid 0.1mg po qd • Standing PRN Example: Tylenol i or ii po q 4 hr for H/A • Short-series order Example: Prednisone 5 mg po tid x 3 days, then 5 mg bid x 2 days then 5 mg qd x 5 days Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 31 Categories of Medication Orders, continued • One time Example: Demerol 50 mg IM @ 0800 in am • Stat Example: Valium 5 mg IV now Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 32 Controlled Substances • Schedule I - This group has a high potential for abuse and is usually nonexistent in a health care setting except for specific, approved research Examples: heroin and marijuana • Schedule II - This group has a high potential for abuse and may lead to severe physical or psychological dependence Examples: Demerol, morphine, codeine Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 33 Controlled Substances, continued • Schedule III - There is moderate or low potential for abuse in this group Examples: Tylenol with codeine, Phenaphen with codeine, Doriden, and Fiorinal • Schedule IV - The potential for abuse is lower in this class than for drugs in schedule III Examples: Talwin, Valium, and meprobamate Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 34 Controlled Substances, continued • Schedule V - The abuse potential of these drugs is limited Examples: Actifed with codeine, Lomotil, Phenergan with codeine, and Triaminic with codeine Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 35 Medications that Have Stop Dates • 3 days Narcotics Analgesics with narcotics Hypnotics • 10 days Antibiotics Anticoagulants • Stop dates vary from hospital to hospital Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 36 Renew Medication Stamp Date Time 00/00/00 0900 Symbol M Doctor, the ___________ Has Expired. Do you wish the ________ Renewed? Yes __ No __ Dr. Signature: _________ Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 37 Lesson 13.2 Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 38 Drug Groups • • • • • • • • • • Drugs that affect the nervous system Drugs that affect the respiratory system Drugs that treat infections: antiinfective drugs Drugs that affect the endocrine system Drugs that affect the cardiovascular system Drugs that affect the gastrointestinal system Drugs that affect the musculoskeletal system Antineoplastics Vitamins Topical preparations Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 39 Drugs that Affect the Nervous System • • • • • • • • Narcotics Analgesics with narcotics Analgesics (nonnarcotic) Patient-controlled analgesia Sedatives/hypnotics Antianxiety drugs Antidepression drugs Anticonvulsants Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 40 Narcotics • • • • Codeine Meperidine hydrochloride (Demerol) Oxycodone (OxyContin) Morphine sulfate Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 41 Analgesics with Narcotics • • • • Aspirin #1, 2, 3, or 4 Percocet Percodan Acetaminophen (Tylenol) #1, 2, 3 or 4 Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 42 Analgesics (Nonnarcotic) • Acetylsalicylic acid (aspirin) • Ibuprofen (Motrin) • Acetaminophen (Tylenol) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 43 Sedatives/Hypnotics • Zolpidem (Ambien) • Flurazepam (Dalmane) • Temazepam (Restoril) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 44 Antianxiety Drugs • Lorazepam (Ativan) • Diazepam (Valium) • Alprazolam (Xanax) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 45 Antidepression Drugs • Amitriptyline (Elavil) • Fluoxetine (Prozac) • Sertraline (Zoloft) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 46 Anticonvulsants • Phenytoin (Dilantin) • Luminal (Phenobarbital) • Gabapentin (Neurontin) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 47 Drugs that Affect the Respiratory System • • • • • Antihistamines Nasal decongestants Antitussives Expectorants Drugs used to treat asthma and related conditions Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 48 Antihistamines • Desloratadine (Clarinex) • Fexofenadine (Allegra) • Benadryl Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 49 Drugs Used to Treat Asthma and Related Conditions • • • • • Aminophylline Fluticasone (Advair) Albuterol (Proventil, Ventolin) Theophylline (Theo-Dur) Montelukast (Singulair) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 50 Drugs that Treat Infections: Antiinfective Drugs • Antibiotics • Antifungals • Antivirals Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 51 Antibiotics • • • • • • • • • Amoxicillin Azithromycin (Zithromax) Cephalexin (Keftab) Ciprofloxacin (Cipro) Penicillin (Pen Vee K) Clindamycin (Cleocin) Doxycycline (Vibramycin) Vancomycin Gentamicin Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 52 Antifungals • Amphotericin B (Amphotec) • Fluconazole (Diflucan) • Nystatin (Mycostatin) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 53 Antivirals • Acyclovir (Zovirax) • Ribavirin (Virazole) • Zidovudine (Relenza) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 54 Drugs that Affect the Endocrine System • Antidiabetics • Hormones Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 55 Antidiabetics • Oral: Glipizide (Glucotrol) Metformin (Glucophage) • Subcutaneous insulin: Insulin glargine (Lantus) Insulin lispro (Humalog) NPH (pork NPH Iletin II, Humulin N) Insulin, regular Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 56 Hormones • • • • • • • Medroxyprogesterone (Depo-Provera) Hydrocortisone (Solu-Cortef) Prednisone (Deltasone) Estrogen (Premarin) Progesterone (Progestin) Levothyroxine (Synthroid) Testosterone (Andronaq, Histerone) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 57 Drugs that Affect the Cardiovascular System • • • • • • • Antidysrhythmic agents Antianginal agents Antihypertensive agents Diuretic agents Potassium replacements Antilipidemics Anticoagulants Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 58 Antiarrhythmic Agents • Diltiazem (Cardizem) • Digoxin (Lanoxin) • Lidocaine (Xylocaine) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 59 Antianginal Agents • • • • Nitroglycerin (Nitro-Bid) Isosorbide (Isordil) Nifedipine (Procardia) Metoprolol (Lopressor) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 60 Antihypertensive Agents • • • • • • Carvediol (Coreg) Atenolol (Tenormin) Fosinopril (Monopril) Enalapril (Vasotec) Apresoline (hydralazine) Sodium nitroprusside (Nipride), (most commonly used to manage a hypertensive crisis) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 61 Diuretic Agents • Hydrochlorothiazide (HydroDIURIL) • Furosemide (Lasix) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 62 Potassium Replacements • Potassium chloride (Kaochlor, K-Lor, Micro K, Slow-K, K-Lyte) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 63 Antihyperlipidemics • • • • • Gemfibrozil (Lopid) Fenofibrate (Tricor) Atorvastatin (Lipitor) Lovastatin (Mevacor) Simvastatin (Zocor) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 64 Anticoagulants • • • • Warfarin (Coumadin) Heparin (Hepaliean) Enoxaparin (Lovenox) Clopidegrel (Plavix) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 65 Drugs that Affect the Gastrointestinal System • Antacids, antisecretory, and antiulcer drugs • Antidiarrheals and laxatives • Antiemetics and antinausea drugs Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 66 Antacids, Antisecretory, and Antiulcer Drugs • • • • • • • Maalox Mylanta Pepto-Bismol Ranitidine (Zantac) Famotidine (Pepcid) Cimetidine (Tagamet) Omeprazole (Prilosec) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 67 Antidiarrheals and Laxatives Antidiarrheals • Kaopectate • Loperamide (Imodium) • Diphenoxylate (Lomotil) Laxatives • Psyllium (Metamucil) • Bisacodyl (Dulcolax) • Polyethylene glycol (GoLYTELY) • Phosphates (Fleets oral or enema preparation) • Magnesium citrate Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 68 Antiemetics/Antinauseants • Prochlorperazine (Compazine) • Hydroxyzine (Vistaril) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 69 Drugs that Affect the Musculoskeletal System • Antiinflammatory drugs Steroids NSAIDs • Muscle relaxants Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 70 Antiinflammatory Drugs Steroids • Hydrocortisone (Cort-Dome, Hytone) • Prednisone (Deltasone) NSAIDs • Naproxen (Anaprox, Naprosyn) • Sulindac (Clinoril) • Prioxicam (Feldene) • Ibuprofen (Motrin) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 71 Muscle Relaxants • Cyclobenzaprine (Flexeril) • Carisoprodol (Soma) • Orphenadrine citrate (Norflex) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 72 Antineoplastics • • • • • • • Cisplatin (Platinol–AQ) Cyclophosphamide (Cytoxan) Doxorubicin (Adriamycin) Interferon alfa (Intron A) Methotrexate (Folex, Mexate) Tamoxifen (Tamofen) Vincristine (Oncovin) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 73 Vitamins • Phytonadione – vitamin K (AquaMEPHYTON) • Multivitamin (MVI) • Cyanocobalamin – vitamin B12 Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 74 Topical Preparations • Ophthalmic preparations (eye) Bacitracin c polymyxin B (Polysporin ophthalmic ointment and suspension) Bacitracin c polymyxin B and neomycin (Neosporin ophthalmic - ointment and solution) Timolol (Timoptic ophthalmic solution) • Otic preparations (ear) Hydrocortisone c ciprofloxacin Vosol HC otic solution Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 75 Topical Preparations, continued • Preparations for the skin Betadine spray Hydrocortisone Neosporin ointment Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 76 Reagents Used for Diagnostic Tests Doctors’ orders for skin tests: • PPD today: screening test for tuberculosis • Cocci 1:100 now: diagnostic test for coccidioidomycosis (valley fever) • Histoplasmin 0.1 mL today: aids in diagnosing histoplasmosis, a fungal disease Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 77 Medication Stock Supply • Hospitals store a supply of medications on nursing units • When floor stock medicines are ordered from the pharmacy, they are charged to the unit budget Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 78 Medication Carts From Lilley LL, Aucker RS: Pharmacology and the Nursing Process, ed 3, St. Louis, 2001, Mosby. Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 79 Discontinuing Medication Orders • When a doctor discontinues a standing or standing prn order, he or she indicates this by writing an order on the doctors’ order sheet. Example: DC Achromycin 500 mg PO tid Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 80 Medication Order Changes • Medication orders may need to be changed for various reasons • The change may involve the dosage, route of administration, or frequency of a drug already ordered • Whenever a change is made, it is considered a new order and should be written as such on the medication administration record Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 81 Medication Order Changes, continued Examples: Change Demerol 50 mg IM q 4h prn to Demerol 50 mg PO q 4h prn (change in route of administration) Decrease ampicillin 500 mg PO qid to 250 mg PO qid (change in dosage) Change Librium 5 mg PO tid to 5 mg PO qid (change in frequency of administration) Copyright © 2009, 2004 by Saunders, an imprint of Elsevier Inc. All rights reserved. Slide 82