Tips for Proposal Writing - University of Illinois at Chicago

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Office of the Vice Chancellor for Research
New Faculty
Orientation
Office of Research Development
Services
Finding Funding
2
Research Development
Finding Funding
• Searchable Databases
• Limited Submissions
• Internal Funding
Searchable Databases
Search, Save, Alert, Track, & Match
• Pivot-COS - http://pivot.cos.com
• Search, Save, Alert, Track, Match
• Grant Resources Center - www.aascu.org/grc
• Login: uic Password: awards
• Search, Save, Alert, Funded Proposal Library
• Grant Forward
https://www.grantforward.com/signup
• Search, Save, Alert
Limited Submissions
• Sponsor limits on institutional submissions
• Weekly massmail and web updates
• Always an LOI  Sometimes White Paper
 Peer reviewed approval
• MUST have prior authorization to submit
• See http://research.uic.edu/funding/limitedsubmissions
Internal Funding Opportunities
Funding to:
• Develop new pilot data
• Jumpstart new architectural, artistic, or
humanities scholarship
• Initiate multidisciplinary research
• Craft a major external proposal
• Bridge gaps between grants
OVCR Pilot Grants
 Award: Up to $20,000 over 1 year
 Purpose:
• Develop preliminary data
• Leverage extramural funding
 Eligibility:
• FT tenure or tenure track faculty
• Assistant Professors must be within 8 years of terminal degree
• Engineering, Basic Life, Clinical, Natural, & Social Sciences
 Deadline:
• LOI: Fall, 2014
• Application: Fall, 2014
http://research.uic.edu/funding/crb
OVCR Pilot Grants for
Architecture, Arts, and Humanities
This new OVCR initiative is currently
in development and scheduled for an
Autumn 2014 release.
Chancellor’s Discovery Fund
for Multidisciplinary Research
 Awards: Up to $40,000 over 2 years
 Purpose:
•
•
•
•
Foster pilot research using the expertise of 2+ disciplines
Nurture career trajectories of promising early-stage investigators
Leverage extramural funding
Encourage new or early stage collaborations
 Eligibility:
• FT tenure or non-tenure track faculty
• Minimum two Principal Investigators
• 1+ PI must be within 8 years of first faculty appointment
 FY 15 Deadline:
• LOI: Fall 2014 TBD
• Application: Winter 2015 TBD
http://research.uic.edu/funding/internal-funding/cdf
Bridge Funding Program
 Purpose: Short term support to sustain research programs,
laboratories, and momentum of productive researchers during
funding gaps to give them a chance to regain extramural
funding.
 Eligibility:
• Full time (at least .8 FTE) senior faculty. Preference will be
given to Associate Professors
• Must have been PI on a grant funded at least three
consecutive years (the same grant or project) by a national
agency with a bona fide scientific peer-review process (e.g.
NSF, NIH, AHA)
Funding: 20K for one year or less. Must be matched 1:1
 Next deadline: TBD, Typically 2-3 times annually

http://research.uic.edu/funding/bridge_funding
Ignite Proposal Development
Program
 Purpose: Spark proposal planning or
development process
 Eligibility:
• Lead PI must be tenured or tenure track faculty
and have a full-time (at least .8 FTE) UIC
appointment
• Project must involve 3 or more colleges

Awards: 20K for a six month term
 AY 2014 deadlines: TBD
http://research.uic.edu/funding-opportunities/ignite
RDS Contact Information
Room 310 AOB
1737 West Polk Street
Phone 312-996-7036
Email: rds@uic.edu
URL: http://www.research.uic.edu/funding
Office of Research
Services (ORS)
What is ORS?
•
•
The Office of Research Services (ORS) is
the central University office responsible
for all pre-award and non-financial postaward sponsored project activities for the
Chicago, Rockford and Peoria campuses
of the University of Illinois.
ORS supports faculty from development
to award stage.
ORS Responsibilities
• Review proposal submissions including
budgets
• Provide technical assistance on electronic
research administration
• Negotiate and execute all award
documents/contracts
• Monitor sponsor guidelines and policy updates
• Ensure compliance with sponsor and
University guidelines and policies
• Conduct educational outreach (workshops,
seminars and open forums)
Sponsors and Activities
•
Sponsors may include, federal, state,
municipalities, foundations, private sector (e.g.
associations, international, bio-medical,
pharmaceuticals).
•
Types of activities may include: Research,
Instruction, Public Service, Technical Testing,
Clinical Trials, SBIR/STTRs, Data Use
Agreements, Non-Disclosure and
Confidentiality Agreements, Collaborative
Agreements, Material Transfer Agreements.
ORS Authority
• ORS is the authorized institutional
representative for sponsored project
activity and provides institutional
endorsements on proposal
submissions.
• ORS has delegated Board of Trustees
signature authority to bind the
university on sponsored research
agreements and award acceptance.
ORS on the Web
•
•
UIC Office of the Vice Chancellor for Research –
Sponsored Programs
• Preparing a Proposal
• Award/Contract Processing & Acceptance
• Award Administration
• Award Closeout
• UIeRA Pre-Award System
• Forms & Contract Templates
• Policies
• Education & Training
• I'm Looking for...
http://research.uic.edu/sponsored_programs
Office of Research Services
Room 304 AOB
1737 West Polk Street
Phone 312-996-2862
Email: ors@uic.edu
URL:
http://research.uic.edu/sponsored_programs
Questions?
Office for the
Protection of
Research
Subjects
(OPRS)
Goal of the UIC Human Subjects
Protection Program
To ensure a comprehensive Human Subjects Protections
Program (HSPP):
• Utilizing the highest ethical and professional
standards
• Affording the highest possible protections for our
human subjects
• Minimize risk to subjects; and
• Maximize benefits of the research.
Keys to Successfully Navigating the IRB
Review Process…
Utilize Resources
Contact OPRS: 312-996-1711 or uicirb@uic.edu
On-line Help:
“Preparation for Submission” Link:
www.research.uic.edu/protocolreview/irb/getting_sta
rted.shtml
Preparation for Submission – Includes
information about:
“Human Subjects Research”
“Key Research Personnel”
Investigator Training requirements
The role of the UIC IRB
The types of protocol review, including:
Determinations
Exemptions
Expedited IRB Review
Convened (full) IRB review
Others: Amendments, CR, Prompt Reports
Decision Trees (e.g. medical record review research)
Tips for obtaining informed consent
Helpful links
Complete Investigator Training ASAP
Initial Investigator Training (Investigator 101)
• On-Line CITI “Basic Course”; or
• In-Person “Investigator 101”
HIPAA Research Training (if research involves PHI)
• On-Line via LMS; or
• In-Person
Note: UIC cannot accept applications unless PI training has been completed
and is current.
Link to Education and Training:
http://research.uic.edu/compliance/irb/education-training
Training Questions: oprstraining@uic.edu
Sign-up for the OPRS Newsletter
Sent electronically
• News for Investigators
• Tips for Investigators
• QIP Corner
• Continuing Education Opportunities
• UIC Data Security Policy Information
Archived on OPRS Web-site
Sign up: Contact OPRS Assistant to the Director, Nora Cortes:
nreyes@uic.edu
Consider Attending Boot Camp
Sponsored by UIC Center for Clinical and
Translational Science and the OVCR.
Three-day training programs:
Clinical Research Boot Camp: October 10th, 17th &
24th
S-B-E Research Boot Camp: Spring 2015, dates
pending.
See Flyer for more information.
28
OPRS Contact Information
West Side Office: Room 203B, AOB,
• 1737 West Polk Street
• Phone 312-996-1711
• Email: uicirb@uic.edu
East Side Satellite Office (M,W 2 – 4 pm)
• Room 3108A, BSB
• Phone 312-996-7742
OPRS URL: http://research.uic.edu/compliance/irb
Questions?
Office of
Animal
Care and
Institutional
Biosafety
(OACIB)
Office for Animal Care and Institutional
Biosafety
OACIB provides administrative support for the review and approval of research
protocols (experiments) involving animals, recombinant DNA and infectious
agents, and ensures compliance with regulations related to the use of controlled
substances in animal and laboratory research. The goal of the office is to facilitate
the protocol writing/review process and navigation of the regulatory issues to
ensure compliance with the regulations for the protection and welfare of
animals, protection and safety of investigators, and the University.
Animal Care
Committee (ACC)
Oversight for all
use of all live
vertebrate animals
in
 Research
 Testing
 Teaching
Animal Care
Committee (ACC)
OLAW/NIH
USDA
AAALAC
SPONSOR
GUIDE
ILAR
DEA
IDPR
Office for Animal Care and Institutional
Biosafety
OACIB provides administrative support for the review and approval of research
protocols (experiments) involving animals, recombinant DNA and infectious
agents, and ensures compliance with regulations related to the use of controlled
substances in animal and laboratory research. The goal of the office is to facilitate
the protocol writing/review process and navigation of the regulatory issues to
ensure compliance with the regulations for the protection and welfare of
animals, protection and safety of investigators, and the University.
Institutional Biosafety
Committee (IBC)
Oversight of all
research involving
rDNA
Infectious
agents/toxins
Select Agents
(EHSO)
Institutional Biosafety
Committee (IBC)
OBA
CDC
USDA
Office for Animal Care and Institutional
Biosafety
Who needs a
protocol?
Protocols are needed if
research involves the use of
animals, rDNA, &/or infectious
agents and
 is conducted at UIC, or
 is conducted by UIC students
&/or
paid personnel, or
 is conducted using funds
administered by UIC including
subcontracts and consortiums.
Responsibilities?
Protocol approval is required
prior to
 Prior to initiation of any use of
animals
 JIT or acceptance/transfer of a
funding award proposing the
use of animals
 simultaneous with the initiation
of some rDNA work (e.g. in vitro
BSL 1)
 prior to the initiation of some
rDNA work (e.g., all viral
vectors, use in animals, use in
humans)
 prior to the initiation of all
infectious agent work
Office for Animal Care and Institutional
Biosafety
Who needs to be
on the protocol?
Personnel need to be listed
on a protocol if they are:
 PI
 PI of a grant supported by the
protocol (must be Co-PI on the
protocol. PPG, Form G protocol
exceptions)
 Working in any capacity with
live animals or with rDNA/IA
 Research Coordinators who
need to receive copies of
correspondence from OACIB
related to protocol issues.
Responsibilities?
 Know what is approved on the
protocol species/strains
 specific procedures
 specific experiments
 specific endpoints or
monitoring
 no migration
 Have expertise or get
appropriate training in
techniques/procedures to be
performed
 Get approval for changes
prior to initiation
Office for Animal Care and Institutional
Biosafety
Facilitating excellence in research at UIC
ACC Forms and
Training
Protocols
Form A*
Form B
Form C
Form G
Appendix 1a, 1b, 1c
Appendix 2
Appendix 3*
Modifications
Form D
Training
ACC
Project Specific
Process and Timing
Protocols
 ~ 6 weeks
No expedited Review
Vet
Subcommittee
Full Committee
Modifications
Administrative
- 3-7 days
Designated Reviews
- 1-6 weeks
Full
- 1-6 weeks
Office for Animal Care and Institutional
Biosafety
Facilitating excellence in research at UIC
IBC Forms and
Training
Protocols
Form A
Form B
Form D
Appendix 1
BSL1 Manual
BSL2 Manual
Modifications
Form C
Training
BBP
DOT/IATA
Select Agents
Process and
Timing
Protocols
2 weeks
Prereview
Expedited
Full
Modifications
Expedited
- 3-7 days
Full
-1-4 weeks
Office for Animal Care and Institutional
Biosafety
Facilitating excellence in research at UIC
Post-Approval
Post-Approval
ACC
IBC
Animal Facility
Orientation
Occupational Health
Card Access
Lab Inspections
BSC Certifications
Account Creation
Animal Orders
Approved
Unapproved
DEA Licenses
Modifications
Form D
Annual Renewal
Triennial Review
Modifications
Form C
Annual Training
Triennial Review
Office of Animal Care and Institutional
Biosafety
Web Sites
ACC: www.research.uic.edu/protocolreview/acc/index.shtml
IBC: www.research.uic.edu/protocolreview/ibc/index.shtml
Controlled Substances:
www.research.uic.edu/protocolreview/cs/index.shtml
Meeting Dates
Forms
Education/Training
Policies/Guidance
FAQs
Online Resources
Contact Information
Office of the Vice Chancellor for Research
Facilitating excellence in research at UIC
Chemicals
X-rays
Office of Animal Care and Institutional
Biosafety
Regulations Pertaining to Research
Animals
rDNA
Infectious Agents
Toxins- Biological
Controlled Substances
Select Agents
Humans
Chemicals
Radionucleotides
X-rays/Irradiators
Lasers
Embryonic Stem Cells
Conflict of Time/Commitment
Conflict of Interest
Import/Export
Material Transfer
Contact Us
Office of Animal Care and Institutional Biosafety
Mary Bowman, PhD, Director
Room 206 AOB
1737 W. Polk
Phone: 312.996.1972
Email: mbb@uic.edu
Questions?
Conflict
of
Interest
(COI)
Conflict of Interest
The Changing Environment
• Federal regulations
• University Policy
Main Points
• COI Defined
• COI and RNUA
• Reporting and Managing Conflicts
• COI Resources
Conflict of Interest
What is financial conflict of interest?
“A ‘conflict of interest’ arises when an academic staff member is in a
position to influence either directly or indirectly University business,
research, or other decisions in ways that could lead to gain for the
academic staff member, the staff member's family, or others to the
detriment of the University's integrity and its missions of teaching,
research, and public service.”
 “Family" is defined as one's spouse or domestic partner,
parents, siblings and children.
 Conflicts reside in a situation, and do not imply
improper behavior.
Conflict of Interest
Who is covered by the policy?
“All paid academic staff members, whether part time or full time, of
the University of Illinois. The academic staff includes the faculty
ranks of professor, associate professor, assistant professor (and all of
the foregoing whose appointments contain such terms as 'research,'
'adjunct,' 'visiting,' or 'clinical'), instructor, and lecturer, as well as
academic professionals and postdoctoral associates.”
• Any paid, non-0% appointment.
• Students, including medical residents, are not considered
academic staff.
Conflict of Interest
Report of Non-University Activities
(RNUA)
Annual Reporting of Non University Activities is the implementation of
conflict of interest policies and regulations for both conflict of interest
and conflict of commitment.
• All academic staff complete the form, even if there are no outside
activities to disclose.
• 24/7 during the contract period.
Resolution always begins with RNUA disclosure and sometimes
involves a combination of conflict management techniques.
Conflict of Interest
PHS FCOI Regulations (2011)
These regulations require HHS, PHS, and NIH Investigators and
senior/key research personnel to:
•Disclose significant financial interests (SFIs) at the time of proposal
submission
•Disclose sponsored or reimbursed travel at the time of proposal
submission
•Update disclosures within 30 days of any newly acquired or discovered
SFIs
•Manage Financial Conflicts of Interest (FCOI) prior to execution of an
award or continuing review
•Complete mandatory University training on Financial Conflicts of
Interest (FCOI)
Conflict of Interest
How to report and manage COI
Annual Disclosure
•Annual Report of Non-University Activities (RNUA)
 RNUA-Management Plan (RNUA-MP) for situations that
require more management (e.g., faculty involved in start-up
companies).
•HHS/PHS/NIH – Significant Financial Interest – Disclosure and
Management Plan: Part I
 SFI-DMP: Part II when University designated officials
determine SFI represent a FCOI
Transactional Disclosure
• PAF – COI Certification
• IRB protocols applications – COI section
Conflict of Interest
How to report and manage COI
Unit Executive Officer
 Holds primary responsibility for working with the academic
staff members to manage conflicts.
UIC Conflict Review Committee (CRC)
 Advisory to the Vice Chancellor for Research.
 Reviews RNUA-management plans and other management plans
as needed
COI-Human Subject Research (COI-HSR) Committee
 Expedited review of COI disclosures on IRB protocols
 Makes recommendations to the IRB.
Conflict of Interest
COI Resources
Online
 All RNUA materials (forms, instructions, more)
 Managing conflicts (templates, instructions, committee
info)
 Policy, rules, regulations
 FAQs
In Person
 Phone, email help
 Strategy, guidance, and oversight meetings
 Educational presentations
Contact US
Jacquelyn Jancius, COI Director
Phone: 312-996-4070
Email: coi@uic.edu
Scott MacEwen
COI Coordinator
Phone: 312-996-3642
Email: coi@uic.edu
http://research.uic.edu/compliance/coi
Questions?
Research
Integrity
You have recently initiated a working relationship with
a new collaborator. One day, as you enter the
collaborator’s lab, you overhear his two post-docs
talking about your joint research project. They sound
defeated and annoyed. One said< “This study is no
different than all the others we have done. Again, we
need to figure out how to get the results he wants to
demonstrate.” The other responds, “we just will have
to figure out what data points to omit so that he gets
the results he wants. I really thought this time it
would be different because his new collaborator is so
well-respected by his post-docs.
Research Integrity at
UIC
• Goal
promote compliance with the highest scholarly standards
• Purpose
provide impartial fact-finding and fair adjudication of
allegations research misconduct
• Policy
UI Policy and Procedures on Integrity in Research and Publication
http://research.uic.edu/node/1437/policies/policies
PHS Policies on Research Misconduct
42 CFR 50 and 93 (rev. 2005)
http://ori.hhs.gov/sites/default/files/42_cfr_parts_50_and_93_2005.pdf
Research Integrity at
UIC
Research Misconduct includes fabrication,
falsification, or plagiarism in proposing, performing,
or reviewing research, or in reporting research
results.
• Fabrication: making up data or results and recording/reporting
them
• Falsification: manipulating research materials, equipment, or
processes, or changing or omitting data or results such that the
research is not accurately represented in the research record
• Plagiarism: appropriation of another person’s ideas, processes,
results or words without giving appropriate credit
• Does not include honest error or difference of opinion
• Any other conduct that constitutes a serious deviation from
accepted ethical guidelines and professional standards in
scholarship
and research
Research Integrity at
UIC
Section V.B
• Any member of the University community who has information
related to potential Research Misconduct has a duty to report
such
information to the Respondent’s UEO or to the RIO…
Section V.B .1
• Institutional members…have an obligation to provide evidence
relevant to Research Misconduct allegations to the RIO or other
institutional officials.
Contact Us
Mark D. Grabiner, PhD
Associate Vice Chancellor for Research and Research Integrity
Officer
Phone: 312-996-2757
Email: grabiner@uic.edu
Website: http://research.uic.edu/compliance/research-integrity
Questions?
Research
Resources Center
(RRC)
• Assures accessibility of shared resources to all
researchers in the UIC community
• Serves >1,000 investigators, $160M 013 grants
• $8 M operating budget, 45% subsidy
• 60 staff; full-time PhD lab directors in each facility
• Faculty Academic Directors
• East and West Campus central facilities
Recent Advancements
• $13M new capital equipment since 2010
• New Imaging Center: Latest Confocal, Multiphoton, TIRF Scopes,
Vectra tissue imaging
• Aberration-corrected STEM: very high resolution EM
• Small animal imaging: 9.4T MRI, IVIS live animal imager, VEVO
Echo
• New Mass Specs: Orbitrap Velos Pro, AB Sciex 5500, 6500
• Genomics Center: High-throughput Genotyping; Next-Gen
sequencing; digital PCR
• Informatics Center
• Drug Discovery Center: High-throughput Screening
• Nanotechnology Facility: Atomic Force Microscope; laser 3-D nano
printer
Center for Structural Biology
Ben Ramirez, Director
•
•
•
•
Most advanced NMR in Chicago: 600, 750, 800, 900 Mhz
X-ray Crystallography
Biacore molecular interaction analysis
Analytical Ultracentrifugation, Calorimetry, Fluorescence
• Production and purification of proteins
Flow Cytometry Service FCS: Balaji Ganesh, Director
Seven flow cytometers:
• new Astrios 6 way sorter
•Beckman MoFlo sorter
•Bio-Plex multiplex quantitative assays
•5 flow cytometry analyzers: CyAn, BD
Fortessa, Beckman Gallios
Becton Dickinson Fortessa
Beckman Coulter MoFlo
Transgenic Production Service: Roberta Franks, Director
A resource for investigators seeking to generate transgenic
and gene-targeted mice for their research activities.
NEW: Genome Editing Facility using CRISPR/CAS
Imaging:
Cellular and Molecular Microscopy: Peter Toth, Director
Newly renovated 2500 sq ft microscopy suites
State-of-the-art imaging technology for fixed, live cells & tissues.
Imaging techniques: live-cell, confocal, FRET, FRAP, FLIP, TIRF,
PhotoActivation, and real time recording of micro- injection.
Two new Zeiss LSM710 confocals, VivaView live-cell long-term
imaging, Prairie Systems Multiphoton microscope, TIRF System
Newly upgraded
ELECTRON MICROSCOPY SERVICE: Alan Nichols, Director
Scanning (SEM), transmission (TEM) and scanning transmission (STEM) electron
microscopes as well as Raman spectroscopy and surface analysis (XPS)
Two laboratories: E5, Medical Sciences Building - SEM and Life Science TEM
Room 116, SES - Materials Science TEM/STEM, Microprobe, Surface Analysis & Raman
NEW: JEOL JEM-ARM200CF TEM/STEM
with cold field emission source
CEOS probe aberration corrector
Animal Imaging and phenotyping
Preclinical MRI Facility: 2,000 sq. ft. animal
imaging laboratory equipped with a new Agilent
9.4 Tesla MRI system that is able to image
small animals and samples up to 7.5 cm in
diameter.
The Xenogen IVIS® Spectrum in vivo uses optical
imaging technology to non-invasive longitudinal
monitoring of disease progression, cell trafficking
and gene expression patterns in living animals.
CCVR:
Surgical services: Trans aortic constriction; Coronary
artery ligation; Osmotic plant implantation
Imaging: VisualSonics Vevo770 ultrasound
Biorepository
• Institutional resource for processing and storing human tissue samples for research purposes.
• LN and -85 freezers house blood, serum, plasma, urine, nucleic acids, & PBMC specimens
• IRB-approved opt-in protocol; Investigator protocols- 15 current
• Pathologists, Path assistants, clinical coordinator assist investigator studies
SERVICES INCLUDE:
•Separation of serum, plasma, PBMCs, urine, and saliva.
•Nucleic Acid isolation
•Opt-in or PI protocol; all samples bar coded and annotated
•Specimen management database; Secure storage
Research Histology and Imaging Core (RHC):
Andy Hall, Director, Histology; Ryan Deaton, Director Imaging
•
•
Instrumentation and services for tissue specimen processing, staining and
imaging.
VECTRA and Aperio imaging instruments
Center for Genomic Research
Staff: Co-Directors, 8 full time technicians, 4 students
Services:
• Next-Generation Sequencing:
Ion Torrent PGM/ Proton/ Illumina
• Microbiome analysis, Whole genome,
Target-capture, ChIP-seq
• CE Sequencing
• Quantitative analyses- QPCR/Digital
• Automated Nucleic Acid purification
• Gene expression analysis: RNAseq,
Affymetrix microarray, Quantigene
• High Throughput Genotyping, CNV
• Cytogenomics
BioInformatics Service- CRI
Director: Neil Bahroos, Chief Research Information Officer
For analysis of big datasets from Genomics/Sequencing, Clinical
Resources
Integrated with Genomics, Clinical Data Warehouse, computing
IT and Biorepository
Staff: 16 total
• 4 Bioinformaticians specializing in analysis of genome
sequencing, gene expression, genotyping, pathways
• 4 Clinical data analysts, natural language processing
Computing resources
• Mixed cluster (GPU/CPU)
• HPC: 3,000 core/ 1.1Pbyte storage
• UIUC computing resources
New 3,000 sq ft facility in CME
Mass Spectrometry, Metabolomics and Proteomics
Richard van Breemen, Academic Director; Alex Schilling, Director
Services Provided
• LC-MS and LC-MS-MS
• MALDI MS and MS-MS
• Quantitative Analysis
• Structure Elucidation
• Protein Identification
• Metabolite Identification
Thermo Velos Orbitrap
Pro funded by NCRR
Fitted with Chip Cube
Thermo LTQ-FT
LC/MS/MS
Informatics Tools
2 Agilent 6410 Triple quads
ChipCube system
Waters Synapt
QTOF MS; ion
mobility
New Triple-Quad Trap ABSciex 5500 & 6500
Nanotechnology Core Facility: Tony DiVinere, Director
Access, training, service and process guidance on fabrication and
characterization equipment.
Application of integrated circuit and fiber optic technology to improve
manufacturing methods for MEMS/Nano devices, BioMEMS,
Microfluidic, Electromechanical, Mechanical, Chemical, Optical,
Photonic and multi-functional devices
NEW: Atomic Force Microscope; laser 3-D nano printer
Scientific Instrumentation Shop: Eric Schmidt, Director
Design and construction of instruments; Instrument repair
Scientific Supply Center: Jennifer Beck, Manager
Media, enzymes, chemicals, glassware at discount prices
Contact US
William Hendrickson
Director, RRC
Phone: 312-996-5600
Email: whend@uic.edu
Website: http://www.rrc.uic.edu
Questions?
Biologic Resources
Laboratory
(BRL)
Biologic Resources Laboratory
•
•
UIC’s Centralized Animal Research Facility
Oversight of the institution’s animal care and use
program
•
•
•
•
•
•
•
Support research
Daily care and husbandry of all laboratory animals
Procurement of all animals
Ensure animal welfare
Ensure compliance with regulatory agencies
Ensure the health status of animal colonies
Train students, staff, and faculty
Biologic Resources Laboratory
Program Scope
•UIC’s
Animal Care and Use Program
has been continually accredited by
AAALAC International since 1970.
•137,000 sq. ft.
•10 satellite facilities
•House over 20 species
•Ave. daily census 32,000 animals
• Mice 30,000
Biologic Resources Laboratory
Program Scope
•
Staff - 62
•
•
•
•
•
•
10 vets – 5 board certified, 5 post-docs
7 veterinary technicians
37 husbandry staff
6 administrative staff
1 enrichment specialist
1 machinist
Biologic Resources Laboratory
Animal Based Research Scope
•275
investigators
•700 active research protocols
•Types of studies
•
•
•
•
•
•
•
•
Cancer
Immunotherapy
Radiobiology
Infectious disease
TransplantationHeart Disease
Diabetes
Neurologic disease
Retinal diseases
Biologic Resources Laboratory
Services
•
To gain access to any of the facilities
• Listed on an approved ACC protocol
• Orientation with one of the veterinarians
• Visit employee health and enroll in the occupational
health and safety program
Biologic Resources Laboratory
Services
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Centralized surgery
Diagnostic laboratory
Radiology section
Antibody production service
Cross foster rederivation program
Support Good Laboratory Practice Studies
Support bio and chemical hazard work
Irradiator
Metabolic cages
Rodent quarantine
Resource
Biologic Resources Laboratory
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Main phone number 312-996-7040
Website http://www.brl.uic.edu/
• Key contacts
• Fee schedule
Animal per diem rate
Diagnostic lab services
Surgery services
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Jeffrey Fortman, Director Biologic Resources Lab
• 312-996-1220
• jdf@uic.edu
Questions?
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