Recovering the
Romanovs Day 1
Forensic Science 2/3/14
S
Drill
S Q 12-14 from DNA review packet
S Put Interpreting DNA Analysis out on desk to be
checked.
S Get packet when done
S HW: Finish Ch 13 Review (fill in the blank)
S NOTE: We will be isolating DNA on Wednesday –
lab!
What is PCR? Why is it useful to
forensic scientists?
S PCR stands for polymerase chain reaction.
S It is a technique that amplifies DNA, so that if
a forensic scientist found a tiny quantity of
DNA, it could still be used in an investigation.
Q13. What are tandem repeats?
How are they useful to forensic
scientists?
S Tandem repeats are regions of a chromosome
that contain multiple copies of a core DNA
sequence arranged in a repeating fashion.
S They are useful to FS because they offer a
means of distinguishing one individual from
another through DNA typing.
Q14. What was the dominant DNA
typing procedure in the US until the
mid-1990s?
S Until the mid-1990s, restriction fragment
length polymorphisms (RFLP) was the
dominant DNA typing procedure in the United
States.
Objectives
S IWBAT
S Investigate the real-life case of Anastasia Romanov,
using forensic techniques.
Recovering the Romanovs
S You will spend today and tomorrow investigating the
case of Anastasia Romanov.
S NOTE: Pd. 5 & 6 – if you will be at the ice cream
social tomorrow, you will need to finish this at
home.
S Before we get started, let’s review Punnett Squares and
Mendelian genetics.
Punnett Square Examples
S TT x tt
S Tt x Tt
S XY x XX
S XY x X’X
S X’Y x X’X
S What is hemophilia?
Now…
S Work on Recovering the Romanovs with your table –
one group come up to the front!
S http://www.dnai.org/d/index.html
S Click Recovering the Romanovs
Closure
S Create a Punnett Square in your Drill/Closure section
that shows the inheritance of hemophilia in Tsar
Nicholas and Alexandra.
S What if Tsar Nicholas had hemophilia? What
percentage of children would have had the disorder?