Investigation of the Cell Cycle Introduction Background Task Process Resources Evaluation Introduction Your job, should you choose to accept it, is to investigate the normal growth pattern of a cell. Then, you will investigate the uncontrolled growth of cells known as cancer. You will be provided with the proper links to navigate through the webquest. Your final product will be a compilation of (4) written assignments, as well as a 2 page paper on cancer. The required written portion is explained in each link. Have fun! Home Background: Cells contain genetic information in a substance called DNA. Chromosomes are the structures found in the nucleus of a cell that contain DNA. A copy of a chromosome can be made during a process called replication. When one cell divides into two identical cells, each cell gets a copy of each chromosome. Mitosis is the name given to the process of one nucleus splitting into two identical nuclei. Mitosis is critical for asexual reproduction. Home Webquest Task The following slide provides a list of links related to cell cycle and cancer. You must visit each of the links and complete the task related to that link. Instructions are provided in each link. You will put the title of each link on a separate page, then record the required information for each site that you visit. Home Process The process is to follow the “Journey to the Cell Cycle” slide to each of the three links listed on that slide. Once you have arrived at the link, you will be instructed what your written assignment is for that segment. Journey through the cell cycle Learn about Mitosis Learn about Cell Cycle Learn about Cancer Learn about Mitosis Complete the following activities: Visit the Cells Alive website. When you are there, click on cell biology on the left side of the screen. Then select Mitosis. Watch the video. Assignment #1: Write a brief description of each of the phases of Mitosis - Sketches are required!! You will also be required to name each of the (4) phases. When you have read and understood these directions click here to go to the Cells Alive site. To return to the Journey, click Resources Investigate the Cell Cycle A cell can divide many times and thus produce many, many identical cells. Between divisions a cell just needs time to grow in size and to make another copy of each chromosome. Investigate this cell cycle by returning to Cells Alive. This time, click on cell cycle on the left side of the screen. Watch the animation, then: Assignment #2: Draw a pie chart that depicts time spent in interphase/ time spent in Mitosis / time spent in Cytokinesis Briefly label each piece of the pie describing what is occuring in the cell during each phase. To go back to Cells Alive, click here. To return to the journey, click Resources. Cell Growth Now that you have learned about normal cell growth and division, you need to understand what goes wrong in cancer. Cell Biology and Cancer Please watch animations 1-5 to learn what goes wrong when cancer strikes!! Now….. Investigating Cancer In this final portion of the webquest, you will gather information to write a minimum two page paper about a particular type of cancer (you may choose a topic that interests you!). The links below will serve as your resources. The paper must include: • Definition of the disease • Causes and possible genetic links • Prevention • Treatment Options • Any related information The following links will assist you: The National Cancer Institute National Cancer Society Cancer.Net Centers for Disease Control Grading Rubric Phases of Mitosis 10 7 3 Points Points Points Accuracy All phases are accurately drawn and labeled Most phases are accurately drawn and labeled, minor discrepancies Major inaccuracies in the drawing and/or labeling of the phases Neatness Phases were neatly drawn, acceptable detail Phases were not drawn neatly, and/or not legible Total Points Phases were neatly drawn with attention to detail Total Points X2 X2 Grading Rubric Cell Cycle Pie Chart CATEGORY 4 3 2 1 Title Title is creative and clearly relates to the subject of the pie chart. It is printed at the top of the pie chart. Title clearly relates to the pie chart and is printed at the top of the pie chart. A title is present at the top of the pie chart. A title is not present. Neatness and Attractiveness Exceptionally well Neat and relatively designed, neat, and attractive. attractive. Colors that go well together are used to make the graph more readable. Lines are neatly Appears messy and drawn but the graph "thrown together" in appears quite plain. a hurry. Lines are visibly crooked. Grading Rubric Cancer Research Paper CATEGORY 4 3 2 1 Amount of Information All topics are addressed and all questions answered with at least 2 sentences about each. All topics are addressed and most questions answered with at least 2 sentences about each. All topics are addressed, and most questions answered with 1 sentence about each. One or more topics were not addressed. Quality of Information Information clearly relates to the main topic. It includes several supporting details and/or examples. Information clearly relates to the main topic. It provides 1-2 supporting details and/or examples. Information clearly relates to the main topic. No details and/or examples are given. Information has little or nothing to do with the main topic. Organization Information is very organized with wellconstructed paragraphs and subheadings. Information is organized with wellconstructed paragraphs. Information is organized, but paragraphs are not well-constructed. The information appears to be disorganized. 8) Mechanics No grammatical, spelling or punctuation errors. Almost no grammatical, spelling or punctuation errors A few grammatical spelling, or punctuation errors. Many grammatical, spelling, or punctuation errors. Sources All sources (information and graphics) are accurately documented in the desired format. All sources (information and graphics) are accurately documented, but a few are not in the desired format. All sources (information and graphics) are accurately documented, but many are not in the desired format. Some sources are not accurately documented. Conclusion Enjoy your investigation. Submit your written assignment of mitosis and cell cycle with your paper on cancer research. Due Date: _______________ Make sure your name is on each assignment!