Substance Use and Addictive Disorders A Patient-Centered, Evidence-Based Diagnostic and Treatment Process1,2,3 A Presentation for SOMC Medical Education Kendall L. Stewart, MD, MBA, DLFAPA November 16, 2012 This presentation is designed as a problem-based learning module. will be amazed by the devastation that substance use will cause in your patients’ lives. 3Some of you and your colleagues will struggle with substance use. When you see it, do the right thing. 1 2You Why is this important? • Substance abuse kills and devastates the living. • It is a huge problem here in Portsmouth. • We still suffer from the reputation of being the world leader of oxycodone prescriptions. • Substance abuse contributes to Scioto County’s being consistently ranked as one of the most unhealthy counties in the nation. • This presentation will provide a foundation for your efforts to lend a helping hand. 1 • After listening to this presentation, you will be able to answer the following questions: – Why is this important? – What diagnoses are included in this DSM-5 Category? – What are some of the demographics of the substance use disorders? – What are some clues to alcohol abuse? – What is the CAGE screening tool? – What medications are helpful? – What counseling techniques are helpful? – What should you do?1,2 Not surprisingly, these people are often untruthful; their families will call you with the real scoop. presentation does not address alcohol, tobacco or gambling. 2 This What diagnoses will likely be included in this category in DSM-5?1 • • • • • • • • • • • • 1 Alcohol-Related Disorders Caffeine-Related Disorders Cannabis-Related Disorders Hallucinogen-Related Disorders Inhalant-Related Disorders Opioid-Related Disorders Sedative/Hypnotic-Related Disorders Stimulant-Related Disorders Tobacco-Related Disorders Unknown Substance Disorders Gambling Disorder Review the proposed revisions here. Further study will be suggested for Caffeine Use Disorder, Internet Use Disorder and Prenatal Alcohol Exposure. What are the diagnostic criteria?1 • Problematic pattern of substance use causing significant impairment or distress – – – – – – – – – – – 1 These are the proposed DSM-5 criteria. Substance used in greater amounts and longer than intended Unsuccessful efforts to cut down usage A great deal of time consumed by substance-related activities and complications A substance-related failure to fulfill obligations at school, work or home Continued substance use in spite of the problems it causes Substance use negatively impacts social, occupational or recreational activities Recurrent use when physically hazardous Continued use in spite of substance-related complications Tolerance Withdrawal Craving How many people (in millions) use drugs each year?1 Hallucinogens 1.1 Cocaine 1.9 Prescription Drugs 6.2 Marijuana 15.2 Methamphetamine 0.3 1 Rakel and Rakel, Textbook of Family Medicine is the huge appeal of marijuana? 2What What are some of the key demographics of substance use?1 • About 8% of us abuse illicit drugs each year. • About 8,000 people try illegal drugs for the first time each day. • Illicit drug use varies by race: – – – – – – – Mixed races 14.1% Blacks 10.1% American Indians 9.5% Whites 8.2% Pacific Islanders 7.3% Hispanics 6.3% Asians 3.6% • Educational level: – High school 8.6% – College 5.7% 1 Rakel and Rakel, Textbook of Family Medicine What are some symptoms of cannabis abuse?1 • Intoxication – – – – – – – – – Pupil constriction Conjunctival injection Headache Increased breathing Increased heart rate Orthostatic hypotension Ataxia Increased appetite Urinary retention • Treatment – Supportive care – Reassurance 1 Rakel and Rakel, Textbook of Family Medicine • Withdrawal – – – – – – – – Irritability Insomnia Restlessness Anorexia Vivid dreams Chills Nausea Sweating • Treatment – Supportive care – Reassurance What are some symptoms of hallucinogen abuse?1 • Intoxication – – – – – – – – – – – Pupil dilation Piloerection Sweating Increased BP Increased pulse Increased reflexes Tremors Seizures Nausea and vomiting Urinary retention Impaired temperature regulation • Treatment – Supportive care – Reassurance 1 Rakel and Rakel, Textbook of Family Medicine • Withdrawal – Fatigue – Irritability – Inability to experience pleasure • Treatment – Supportive care – Reassurance What are some symptoms of inhalant abuse?1 • Intoxication – – – – – – – – – Horizontal nystagmus Increased tears and saliva Pupil dilation Coma with eyes open Sweating Flushing Absent gag reflex Apnea Increased pulse and BP • Treatment – Supportive care – Reassurance 1 Rakel and Rakel, Textbook of Family Medicine • Withdrawal – – – – – – – Depression Anxiety Sleepiness Irritability Sweating Tremor Craving • Treatment – Supportive care – Reassurance What are some symptoms of opioid abuse?1,2 • Intoxication – Miotic pupils – Euphoria – Altered level of consciousness – Constipation – Respiratory depression • Treatment – Naloxone (Narcan) 0.4 to 0.8 and repeated as needed. • Withdrawal – – – – – – – – Strong craving Nausea and vomiting Body aches Insomnia Anxiety Runny nose Yawning Pupil dilation • Treatment – Clonidine (Catapres) – Methadone (Dolophine) – Buprenorphine (Subutex) 1 Rakel and Rakel, Textbook of Family Medicine will be able to see which patients are at risk for addiction. 2You What are some symptoms of sedative abuse?1 • Intoxication – – – – – – Slurred speech Ataxia Respiratory depression Stupor Coma Death (with mixed OD) • Treatment – – – – 1 Respiratory support GI evacuation Activated charcoal Flumazenil (Romazicon) with caution because of increased seizures and cardiac arrhythmias Rakel and Rakel, Textbook of Family Medicine • Withdrawal – – – – – – – – – – – – Tachycardia Hypertension Fever Agitation Hallucinations Insomnia Irritability Nightmares Tremor Anorexia Seizures Delirium • Treatment – Tapering using long-acting sedatives What are some symptoms of stimulant abuse?1 • Intoxication – – – – – – – – – Pupil dilation Headache Increased respiration Chest pain Tremor Seizures Myoclonus Nausea and vomiting Fever • Treatment – Supportive care – Reassurance 1 Rakel and Rakel, Textbook of Family Medicine • Withdrawal – – – – – – – Depression Anxiety Fatigue Increased appetite Craving Increased dreaming Sleepiness • Treatment – Supportive care – Reassurance What is the CAGE1 screen for drug abuse? • Have you ever felt you should cut down on your use of drugs? • Have people annoyed you by criticizing your use of drugs? • Have you ever felt bad or guilty about your use of drugs? • Have you ever used first thing in the morning to steady your nerves or to get rid of a hangover (eye opener)? • (Any positive answer is a source of concern.) 1 Ewing JA, Detecting Alcoholism: The CASE Questionnaire. JAMA 1984; 252: 1905-1907. What counseling techniques may be helpful in alcohol use disorder?1,2 • • • • • 1 Cognitive-Behavioral Therapy (CPT) Contingency Management Motivational Enhancement Therapy Therapeutic Communities Twelve-Step Facilitation Rakel and Rakel, Textbook of Family Medicine the power of a “positive” addiction. 2Recognize What should you do?1 • You must be the change you want to see in the world. Mahatma Gandhi • Become a wellness champion and continue that lifestyle as long as you live. • If you abuse drugs, stop now; if you cannot, seek treatment and stick with it. • Support prevention efforts for kids. • Ask every new patient about drug use. • Understand that many users will lie. • Inquire whether patients who are abusing drugs are ready to stop—at every visit. 1 Rakel and Rakel, Textbook of Family Medicine What else should you do?1 • Seize every teachable moment to urge quitting. • View this as a chronic disease. • Remember that relapse is the rule rather than the exception. • Focus on what you can do instead of fretting about what you can’t do. • Bear in mind that the prognosis is not hopeless. • Never, never, ever give up. 1 Rakel and Rakel, Textbook of Family Medicine The Psychiatric Interview A Patient-Centered, Evidence-Based Diagnostic and Therapeutic Process • • • Introduce yourself using AIDET1. Sit down. Make me comfortable by asking some routine demographic questions. Ask me to list all of problems and concerns. Using my problem list as a guide, ask me clarifying questions about my current illness(es). Using evidence-based diagnostic criteria, make accurate preliminary diagnoses. Ask about my past psychiatric history. Ask about my family and social histories. Clarify my pertinent medical history. Perform an appropriate mental status examination. • • • • • • • • • • • • • • • • • Review my laboratory data and other available records. Tell me what diagnoses you have made. Reassure me. Outline your recommended treatment plan while making sure that I understand. Repeatedly invite my clarifying questions. Be patient with me. Provide me with the appropriate educational resources. Invite me to call you with any additional questions I may have. Make a follow up appointment. Communicate with my other physicians. Acknowledge the patient. Introduce yourself. Inform the patient about the Duration of tests or treatment. Explain what is going to happen next. Thank your patients for the opportunity to serve them. 1 Where can you learn more? • • • • • • • • • • • American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, 2000 Sadock, B. J. and Sadock V. A., Concise Textbook of Clinical Psychiatry, Third Edition, 2008 Stern, et. al., Massachusetts General Hospital Comprehensive Clinical Psychiatry, 2008. You can read this text online here. Flaherty, AH, and Rost, NS, The Massachusetts Handbook of Neurology, April 2007 Stead, L, Stead, SM and Kaufman, M, First Aid© for the Psychiatry Clerkship, Second Edition, March 2005 Klamen, D, and Pan, P, Psychiatry Pre Test Self-Assessment and Review, Twelfth Edition, March 20093 Oransky, I, and Blitzstein, S, Lange Q&A: Psychiatry, March 2007 Ratey, JJ, Spark: The Revolutionary New Science of Exercise and the Brain, January 2008 Medina, John, Brain Rules: 12 Principles for Surviving and Thriving at Home, Work and School, February 2008 Stewart KL, “Dealing With Anxiety: A Practical Approach to Nervous Patients,” 2000 Order the Kindle version of the Rakel and Rakel Textbook of Family Medicine here. Where can you find evidence-based information about mental disorders? • • • • • • • Explore the site maintained by the organization where evidence-based medicine began at McMaster University here. Sign up for the Medscape Best Evidence Newsletters in the specialties of your choice here. Subscribe to Evidence-Based Mental Health and search a database at the National Registry of Evidence-Based Programs and Practices maintained by the Substance Abuse and Mental Health Services Administration here. Explore a limited but useful database of mental health practices that have been "blessed" as evidence-based by various academic, administrative and advocacy groups collected by the Iowa Consortium for Mental Health here. Download this presentation and related presentations and white papers at www.KendallLStewartMD.com. Learn more about Southern Ohio Medical Center and the job opportunities there at www.SOMC.org. Review the exceptional medical education training opportunities at Southern Ohio Medical Center here. How can you contact me?1 Kendall L. Stewart, M.D. VPMA and Chief Medical Officer Southern Ohio Medical Center Chairman & CEO The SOMC Medical Care Foundation, Inc. 1805 27th Street Waller Building Suite B01 Portsmouth, Ohio 45662 740.356.8153 StewartK@somc.org KendallLStewartMD@yahoo.com www.somc.org www.KendallLStewartMD.com 1Speaking and consultation fees benefit the SOMC Endowment Fund. Are there other questions? Justin Greenlee, DO Thomas Carter, DO Safety Quality Service Relationships Performance