PSYCHOLOGICAL DISORDERS Copyright 1998 Allyn & Bacon What Is Normal and Abnormal? A man kissing another man A man barking like a dog A woman slapping a child A woman refusing to eat for several days A man driving a nail through his hand Perspectives on Causes and Treatment of Disorders Biological Perspective Psychodynamic Perspective Learning Perspective Cognitive Perspective Humanistic Perspective Copyright 1998 Allyn & Bacon What is Abnormal? Textbook: “3 D’s” Distressing Dysfunctional Deviance Abnormal Behavior Schizophrenia Based on observation and self report Signs and Symptoms Abnormal content of thought Illogical form of thought Distorted perception Changed affect Impaired sense of self Impaired interpersonal functioning Onset Timing 10 20 30 AGE 40 Period of greatest susceptibility 50 Distinguishing features flat, dull, inappropriate mood, blank stare confused thinking, rambling train of thought detachment, absorption in private world severely reduced motivation, indecision Positive Symptoms of Schizophrenia Hallucinations Delusions Disturbances in Form of Thought or Speech Grossly Disorganized Behavior Inappropriate Affect Copyright 1998 Allyn & Bacon Negative Symptoms of Schizophrenia Social Very Withdrawal Apathy Loss of Motivation Lack of GoalDirected Activity Limited Speech Slowed Movements Poor Hygiene and Grooming Copyright 1998 Allyn & Bacon Types of Schizophrenia Catatonic Disorganized Paranoid Undifferentiated Copyright 1998 Allyn & Bacon Causes of Schizophrenia Genetic Inheritance Excessive Dopamine Activity Copyright 1998 Allyn & Bacon Ventricle Example Cortex Cross-Sections Normal Schizophrenic Genetics? Psychopathology has been noted among children of mothers with schizophrenia than among children in the general population: the population risk for schizophrenia is 1 percent, but the risk for children whose mothers have chronic schizophrenia is 16 percent -- and even higher if the father also has schizophrenia or is in the schizophrenia spectrum (Kallmann 1938; Parnas et al. 1993). Types of Schizophrenia Type I positive symptoms sudden onset responds to antipsychotic meds rapidly Type II negative symptoms poor response to antipsychotic meds brain atrophy??? Phases of Schizophrenia Acute Rapid Episode deterioration, weeks or months Prodromal The term "prodrome" is derived from the Greek word prodromos meaning the forerunner of an event (Fava and Kellner 1991). In clinical medicine, a prodrome refers to the early symptoms and signs of an illness that precede the characteristic manifestations of the acute, fully developed........... illness. For example, measles is described as having a prodrome of 3 to 4 days characterized by fever, coryzal symptoms, conjunctivitis, and cough. This is followed by the specific rash, making definitive diagnosis possible (Yung and Stanley 1989). Prodromal.... clear deterioration not due to substances Typical symptoms marked social isolation or withdrawal impairment in role functioning markedly peculiar behavior digressive, vague or poverty of speech odd beliefs or thinking unusual perceptual experiences Residual Phase Psychotic features may be absent Sense of apathy Difficulties in thinking, language Harboring unusual ideas Subtypes of Schizophrenia Catatonic: rigid posturing, stupor Disorganized: silly, giddy, emotional Paranoid: Delusions of persecution, often anger Undifferentiated Residual type: multiple type: Previous episodes, currently not psychotic, mild signs Other Psychosis Schizophreniform Disorder: same symptoms, 1 - 6 months Schizoafftective Disorder: hallucinations, delusions plus mood disturbances Delusional Disorder Brief Psychotic Episode Substance Induced Psychotic Disorder Psychotic Disorder due to....(specific medical condition) Treatment Childers (1964) concludes that the combination of ECT and drug increases the percentage of patients who attain a moderate or better improvement. Core positive symptoms (e.g., hallucinations, delusions, thought disorder) appear to be significantly reduced by benzodiazepines in some but not all studies. Based on limited data, Plasky (1991) found little evidence of any efficacy of tricyclic antidepressants for the negative symptoms of schizophrenia ECT treatment Erwin and Thompson (1978) believe that ECT does not treat the schizophrenic process but rather treats secondary mood disorders in schizophrenia Patients with schizoaffective disorder and catatonia had the best response rate (85% and 82%, respectively) to ECT. “Talk Therapies” Psychotherapy goals are around management of disorder rather than “cure”. Family therapy is vital to assist in coping. Deal with related emotions....anxiety, depression, frustration, anger Mood Disorders Major Depressive Disorder Seasonal Depression Bipolar Disorder Copyright 1998 Allyn & Bacon Major Depressive Disorder Overwhelming feelings of sadness, despair, hopelessness Loss of interest in pleasurable activities Common Symptoms Mood swings Tearfulness Irritability Apathy Loss of energy Concentration/attention problems Indecision Pervasive mood of sadness Symptoms..... Negativity and pessimism Guilt, self-reproach Psychomotor retardation or agitation Changes in appetite, weight Sleep difficulties Thoughts of death or suicide Withdrawal Feelings of hopelessness Variations in Depression Reactive Endogenous, chronic Drug induced Medically related (surgery, postpartum) Bereavement Agitated depression Seasonal Affective Disorder Dual Diagnosis Substance abuse and psychological disorder Depression common Schools of thought alcohol causes depression (depressant) depression leads to use of alcohol Depression and Suicide When depression goes untreated, its most tragic cost is suicide. Fifteen percent of people in whom depression is overlooked, untreated, or improperly treated, will commit suicide. This means about 20,000 lives each year, in North America alone. Treatment there are two very effective treatments for depression--medication and psychotherapy almost 80% of people with depression improve with these treatments depression becomes more difficult to treat the longer its symptoms go untreated without proper treatment, 10 to 15% of people who suffer depression commit suicide. St John’s Wort There is considerable public interest in claims that extracts from the herb Hypericum perforatum, commonly known as St. John’s wort, may be an effective treatment for depression. Although St. John’s wort is widely prescribed in Europe, clinical research in the USA is incomplete. Gender & Depression (Data from Kessler, et al., 1994) Prognosis (1 year) (APA Data, 1994) Seasonal Affective Disorder A greater than normal mood fluctuation with the seasons Related light to amount & intensity of Seasonal Affective Disorder (After Wurtman & Wurtman,1989) Bipolar Disorder Manic episodes & extreme depression mixed with normal affect Mania involves delusional levels of optimism, euphoria, & energy Equally common in both sexes Sufferers make poor decisions while manic, withdraw when depressed Bipolar Disorder (Data from Kessler, et al., 1994) Genetic Connection Moderate in major depressive disorder Strong in bipolar depression Causes & Treatments Depression: low norepinephrine & serotonin levels Mania: high norepinephrine levels Major Depressive Disorder: serotonin selective reuptake inhibitors (e.g. Prozac) Causes & Treatments Bipolar Depression: lithium carbonate Neurotransmitter levels may be symptomatic of depression, not causal Cognitive theory attributes depression to distorted thinking Distorted Thinking Includes negative views of the world, the future, the self Tied to poor reality testing, learned helplessness Causes of Major Depression and Bipolar Disorder The Biological Perspective The Cognitive Perspective The Psychodynamic Explanation Copyright 1998 Allyn & Bacon Anxiety Disorders Generalized Anxiety Panic Disorder Disorder Phobias Obsessive-Compulsive Disorder Copyright 1998 Allyn & Bacon Anxiety Disorders Fears & Phobias Panic Disorder Generalized Anxiety Disorder Obsessive Compulsive Disorder Phobias: Lifetime Prevalence Obsessive Compulsives Obsessions: persistent, uncontrollable thoughts Obsessive Compulsives Compulsions: intrusive, inappropriate actions that often prevent obsessions Obsessive Compulsives Obsessions Reduce Compulsions Anxiety Somatoform Disorders Hypochondriasis Conversion Disorder Copyright 1998 Allyn & Bacon Dissociative Disorders Dissociative Amnesia Dissociative Fugue Dissociative Identity Disorder Copyright 1998 Allyn & Bacon Other Psychological Disorders Sexual and Gender Identity Disorders Personality Disorders Copyright 1998 Allyn & Bacon