8 Attention-Deficit/Hyperactivity Disorder (ADHD) Eric J. Mash A. Wolfe ©David Cengage Learning 2016 © Cengage Learning 2016 Description • Attention-deficit/hyperactivity disorder (ADHD) is exhibited as persistent ageinappropriate symptoms of inattention, hyperactivity, and impulsivity that are sufficient to cause impairment in major life activities – Characteristic behaviors vary considerably from child to child – Different behavior patterns may have different causes © Cengage Learning 2016 History • Early 1900s – Children who lacked self-control and showed symptoms of overactivity/inattention in school were said to have poor “inhibitory volition” and “defective moral control” • Following the worldwide influenza epidemic from 1917-1926 – “Brain-injured child syndrome” • 1940s-1950s: “minimal brain damage” and “minimal brain dysfunction” © Cengage Learning 2016 Historical Example © Cengage Learning 2016 History (cont’d.) • Late 1950s – ADHD was called hyperkinesis • Led to definition of hyperactive child syndrome, in • By the 1970s – Deficits in attention and impulse control, in addition to hyperactivity, were seen as the primary symptoms • 1980s saw increased interest in ADHD – Rise in stimulant use generated controversy © Cengage Learning 2016 Core Characteristics • Key symptoms fall under two welldocumented categories – Inattention – Hyperactivity-impulsivity • Using these dimensions to define ADHD oversimplifies the disorder – Attention and impulse control are closely connected developmentally © Cengage Learning 2016 DSM-V Diagnostic Criteria for ADHD © Cengage Learning 2016 DSM-V Diagnostic Criteria for ADHD (cont’d.) © Cengage Learning 2016 DSM-V Diagnostic Criteria for ADHD (cont’d.) © Cengage Learning 2016 Inattention • Inability to sustain attention, particularly for repetitive, structured, and less enjoyable tasks • Deficits may be seen in one or more types of attention – Attentional capacity – Selective attention – Distractibility – Sustained attention/vigilance (a core feature) © Cengage Learning 2016 Hyperactivity-Impulsivity • Inability to voluntarily inhibit dominant or ongoing behavior • Hyperactive behaviors include – Fidgeting and difficulty staying seated – Moving, running, touching everything in sight, excessive talking, and pencil tapping – Excessively energetic, intense, inappropriate, and not goal-directed © Cengage Learning 2016 Hyperactivity-Impulsivity (cont’d.) • Impulsivity – Inability to control immediate reactions or to think before acting – Cognitive impulsivity includes disorganization, hurried thinking, and need for supervision – Behavioral impulsivity includes difficulty inhibiting responses when situations require it – Emotional impulsivity includes impatience, low frustration tolerance, hot temper, quickness to anger, and irritability © Cengage Learning 2016 ADHD Presentation Types • Predominantly inattentive presentation (ADHD-PI) • Predominantly hyperactive–impulsive presentation (ADHD-HI) • Combined presentation (ADHD-C) © Cengage Learning 2016 Predominantly Inattentive Type (ADHD-PI) • Inattentive, drowsy, daydreamy, spacey, in a fog, and easily confused • May have learning disability, process information slowly, have trouble remembering things, and display low academic achievement • Often anxious, apprehensive, socially withdrawn, and may display mood disorders © Cengage Learning 2016 Predominantly Hyperactive-Impulsive Type (ADHD-HI) • Primarily symptoms of hyperactivityimpulsivity (rarest group) • Primarily includes preschoolers and may have limited validity for older children • May be a distinct subtype of ADHD-C © Cengage Learning 2016 Combined Type (ADHD-C) • Children who have symptoms of both inattention and hyperactivity-impulsivity • Most often referred for treatment © Cengage Learning 2016 Additional DSM Criteria • Appears prior to age 12 • Persists more than 6 months • Occurs more often and with greater severity than in: – Other children of the same age and sex • Occur across two or more settings • Interferes with social or academic performance • Not explained by another disorder © Cengage Learning 2016 What DSM Criteria Don’t Tell Us • Limitations of DSM criteria for ADHD – Developmentally insensitive – Categorical view of ADHD • DSM criteria shape our understanding of ADHD – DSM criteria are also shaped by, and in some instances lag behind, new research findings © Cengage Learning 2016 Associated Characteristics • Children with ADHD often display other problems in addition to their primary difficulties – Cognitive deficits – Speech and language impairments – Developmental coordination and tic disorders – Medical and physical concerns – Social problems © Cengage Learning 2016 Cognitive Deficits: Executive Functions • • • • Cognitive processes Language processes Motor processes Emotional processes © Cengage Learning 2016 Examples of Impaired Executive Functions © Cengage Learning 2016 Cognitive Deficits: Intellectual and Academic • Intellectual deficits – Most children with ADHD have at least normal intelligence - the difficulty lies in applying intelligence to everyday life situations • Impaired academic functioning – Children with ADHD frequently have lower productivity, grades, and scores on achievement tests © Cengage Learning 2016 Cognitive Deficits: Learning Disorders and Self-Perceptions • Learning disorders are common for children with ADHD – Problem areas: reading, spelling, and math • Distorted self-perceptions – Positive bias: exaggeration of one’s competence – Self-esteem in children with ADHD may vary with the subtype of ADHD – Distortions in perceptions of quality of life © Cengage Learning 2016 Speech and Language Impairments • • • • Formal speech and language disorders Difficulty understanding others’ speech Excessive and loud talking Frequent shifts and interruptions in conversation • Inability to listen • Inappropriate conversations • Speech production errors © Cengage Learning 2016 Developmental Coordination and Tic Disorders • As many as 30-50% of children with ADHD display motor coordination difficulties – Clumsiness, poor performance in sports, or poor handwriting • Overlap exists between ADHD and developmental coordination disorder (DCD) – Marked motor incoordination and delays in achieving motor milestones © Cengage Learning 2016 Developmental Coordination and Tic Disorders (cont’d.) • Tic disorders occur in 20% of children with ADHD – Sudden, repetitive, nonrhythmic motor movements or sounds such as eye blinking, facial grimacing, throat clearing, and grunting © Cengage Learning 2016 Medical and Physical Concerns • Health-related problems – Higher rates of asthma and bedwetting • Studies’ findings are inconsistent – Sleep disturbances may be related to use of stimulant medications and/or co-occurring conduct or anxiety disorders © Cengage Learning 2016 Medical and Physical Concerns (cont’d.) • Accident-proneness and risk taking – Over 50% are described as being accidentprone – At higher risk for traffic accidents – At risk for early initiation of cigarette smoking, substance use disorders, and risky sexual behaviors – Reduced life expectancy – Higher medical costs © Cengage Learning 2016 Social Problems • Family problems include: – Negativity, child noncompliance, excessive parental control, sibling conflict, maternal depression, paternal antisocial behavior, and marital conflict • Family difficulties may be due to cooccurring conduct problems © Cengage Learning 2016 Social Problems (cont’d.) • Peer problems – ADHD children can be bothersome, stubborn, socially awkward, and socially insensitive • They are often disliked and uniformly rejected by peers, have few friends • They are unable to apply their social understanding in social situations • Positive friendships may buffer negative outcomes © Cengage Learning 2016 Accompanying Psychological Disorders and Symptoms • Up to 80% of children with ADHD have a co-occurring psychological disorder • Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) – Role of COMT gene – A common genetic contribution for ADHD, ODD, and CD – Family connections – there is evidence for a contribution from a shared environment © Cengage Learning 2016 Accompanying Psychological Disorders and Symptoms Anxiety Disorders • Anxiety disorders – About 25% of children with ADHD experience excessive anxiety – Co-occurring anxiety worsens symptoms or severity of ADHD • Findings are inconsistent – Children with co-occurring ADHD and anxiety: • Display social and academic difficulties • Experience greater long-term impairment and mental health problems © Cengage Learning 2016 Accompanying Psychological Disorders and Symptoms Mood Disorders • Mood disorders – ADHD at 4-6 years is a risk factor for future depression and suicidal behavior – 20-30% of children with ADHD experience depression • Family risk for one disorder may increase the risk for the other • Controversy regarding relationship between ADHD and pediatric bipolar disorder (BP) © Cengage Learning 2016 Prevalence and Course • Prevalence rates vary widely with sampling methods – Estimates: 6-7% of school-age children and adolescents in North America and 5% worldwide have ADHD – ADHD is one of the most common referral problems seen at clinics © Cengage Learning 2016 Gender • ADHD occurs more frequently in boys • Overall rates decrease in adolescence for both sexes - ratio remains the same • Ratio in clinical samples is 6:1 with boys being referred more often than girls – ADHD in girls may go unrecognized and unreported • DSM criteria (cutoffs and symptoms) may be more appropriate to boys than girls © Cengage Learning 2016 Gender (cont’d.) • Girls with ADHD may be more likely to display inattentive/disorganized symptoms • Clinic-referred school-age children with ADHD display similar symptoms • Girls with ADHD who display impulsivehyperactive behaviors – More likely to develop eating disorder symptoms © Cengage Learning 2016 Socioeconomic Status and Culture • ADHD affects children from all social classes – Slightly more prevalent among lower SES groups • Findings are inconsistent regarding relationships among ADHD, race, and ethnicity • ADHS is found in all countries and cultures – Rates vary © Cengage Learning 2016 Socioeconomic Status and Culture (cont’d.) • Cultural differences may reflect cultural norms and tolerance for ADHD symptoms • ADHD is a universal phenomenon that is diagnosed more often in boys than girls in all cultures – Expression, associated features, impairments, and outcomes are quite similar wherever it occurs © Cengage Learning 2016 Course and Outcome • Infancy – Signs of ADHD may be present at birth - no reliable or valid methods exist to identify it • Preschool – Hyperactivity-impulsivity symptoms become more visible and significant at ages 3-4 – Children with symptoms for at least 1 year are likely to continue to have difficulties later in middle childhood and adolescence © Cengage Learning 2016 Course and Outcome Elementary School • Symptoms are especially evident when the child starts school • Oppositional defiant behaviors may increase or develop – By age 8-12, defiance and hostility may take the form of serious problems – Increased problems may encompass selfcare, personal responsibility, chores, trustworthiness, independence, social relationships, and academic performance © Cengage Learning 2016 Course and Outcome Adolescence and Adulthood • Many children with ADHD do not outgrow problems and some can get much worse • At least 50% of clinic-referred elementary school children continue to suffer from ADHD into adolescence • Adult challenges – Some individuals either outgrow or learn to cope with their disorder by adulthood – ADHD is established as an adult disorder © Cengage Learning 2016 Theories and Causes • Explanations for ADHD – Trait from evolutionary past as hunters – ADHD is a myth fabricated because society needs it – Some theories • Cognitive functioning deficits • Reward/motivation deficits • Arousal level deficits • Self-regulation deficits © Cengage Learning 2016 A Possible Developmental Pathway for ADHD © Cengage Learning 2016 Genetic Influences • ADHD runs in families • Adoption studies • Twin studies – 75% heritability estimates for hyperactiveimpulsive and inattentive behaviors • Specific gene studies – Genes may contribute to the expression of ADHD – focus on dopamine regulation © Cengage Learning 2016 Pregnancy, Birth, and Early Development • Factors that compromise development of the nervous system before and after birth may be related to ADHD • Mother’s use of cigarettes, alcohol, or other drugs during pregnancy are associated with ADHD – Contributing factors, rather than a causal association – It is difficult to disentangle substance abuse influence and other environmental factors © Cengage Learning 2016 Neurobiological Factors • Research shows differences on: – Psychophysiological measures • Diminished arousal or arousability – Measures of brain activity during vigilance tests • Under-responsiveness to stimuli/deficits in response inhibition – Blood flow to prefrontal regions and pathways connecting them to limbic system • Decreased blood flow to these regions © Cengage Learning 2016 Brain Abnormalities • Abnormalities primarily in the frontostriatal circuitry are implicated – This region includes the prefrontal cortex and the basal ganglia – ADHD children have smaller total and right cerebral volumes (by 3-4%), smaller cerebellum, and delayed brain maturation • Specific regions of the thalamus may also be involved © Cengage Learning 2016 Neurophysiological and Neurochemical Associations • No consistent differences have been found between children with and without ADHD – Some neurotransmitters may be involved • Dopamine, norepinephrine, epinephrine, and serotonin may be involved • Most evidence suggests a selective deficiency in availability of dopamine and norepinephrine – Using medication for effective treatment of ADHD symptoms does not prove that deficits are the cause of symptoms © Cengage Learning 2016 Diet, Allergy, and Lead • Sugar is not the cause of hyperactivity • Allergic reactions and diet – Possible moderating role of genetic factors may explain why food additives affect the behavior of some children • Low levels of lead may be associated with ADHD symptoms • The role of diet, allergy, and lead as primary causes of ADHD is minimal to nonexistent © Cengage Learning 2016 Family Influences • Importance of family influences – Family influences may lead to ADHD symptoms or to a greater severity of symptoms – Family problems may result from interacting with a child who is difficult to manage – Family conflict is likely related to the presence, persistence, or later emergence of associated oppositional and conduct disorder © Cengage Learning 2016 Treatment • Less than half of the children with ADHD receive treatment – Of those who receive treatment, many discontinue prematurely • The primary treatment approach combines: – Stimulant medication – Parent management training – Educational intervention © Cengage Learning 2016 Treatments for Children with ADHD © Cengage Learning 2016 Medication • Stimulants have been used to treat ADHD since the 1930s – Among the most effective stimulants are dextroamphetamine and methylphenidate • May help normalize frontostriatal structural abnormalities and functional connections – Effects are temporary and occur only while medication is taken; beneficial in short-term • Questions surround long-term benefits and later adjustment © Cengage Learning 2016 Parent Management Training (PMT) • Provides parents with a variety of skills – Managing the child’s oppositional and noncompliant behaviors – Coping with emotional demands of raising a child with ADHD – Containing the problem so it does not worsen – Keeping the problem from adversely affecting other family members © Cengage Learning 2016 Parent Management Training (PMT) (cont’d.) • Parents are: – Taught to understand biological basis of ADHD – Given set of guiding principles – Taught behavior management principles and techniques – Encouraged to spend time each day sharing enjoyable activity with their child – Taught how to reduce their own levels of arousal © Cengage Learning 2016 Educational Intervention • Teacher and child must set realistic goals and objectives • Response-cost procedures are used to reduce disruptive or off-task behaviors • Many strategies are basic good teaching methods • School-based interventions for ADHD have received considerable support © Cengage Learning 2016 Intensive Interventions • Summer treatment programs – Maximize opportunities to build effective peer relations in normal settings and provides continuity with academic work so gains from school year aren’t lost – Are coordinated with stimulant medication trials, PMT, social skills training, and educational interventions © Cengage Learning 2016 Additional Interventions • Family counseling and support groups – Help family members develop new skills, attitudes, and ability to relate more effectively • Individual counseling – Helps children with ADHD deal with their problems and feelings of isolation and abnormality – Helps build their sense of self-competence © Cengage Learning 2016 Keeping Things in Perspective • Children with ADHD have problems that should not be minimized • Each child is unique and has assets and resources that need to be recognized and supported © Cengage Learning 2016