22/03/2016 How do we prevent bacteria spreading ? 22/03/2016 Answer Q 1-4 in full sentences (Q 2 may be done by completing the table. 22/03/2016 Agar jelly 22/03/2016 Is used to grow microbial populations in. It contains all of the necessary nutrients for a microorganism to grow on. Aim To investigate the effectiveness of different had washing methods for removing bacteria. Independent variable Dependent variable Control variable Prediction Agar jelly Control no washing Agar jelly 22/03/2016 Method 1. Set up apparatus as shown. Treatment 1 2. Label lid with treatments and your name. Treatment 2 3. Seal lid 4. Leave for 1 week (take a picture) Defense against disease 22/03/2016 1. Describe how the body protects its self from disease 2. Know how a vaccine works 3. Be able to use correct scientific terminology when describing vaccinations and the immune system. Microbes: our defence against them 22/03/2016 Our bodies have many defence mechanisms against invading microbes: The skin acts as a barrier Stomach produces stomach acid to kill bacteria If our skin is cut platelets seal the wound by clotting Tears contain an enzyme that kills bacteria The breathing organs produce mucus to cover the lining of these organs and trap the microbes. Ciliated cells sweep the mucus out. Fighting disease 22/03/2016 If microbes do enter our body they need to be neutralised or killed. This is done by WHITE BLOOD CELLS: White blood cells do 3 things: 1) They eat the microbe-engulf the microbes https://www.youtube.com/wat ch?v=Z_mXDvZQ6dU Fighting disease 22/03/2016 If microbes do enter our body they need to be neutralised or killed. This is done by WHITE BLOOD CELLS: White blood cells do 3 things: 2) They produce antibodies to neutralise the microbe You’re going down Step 1: The white blood cell detects the antigen (microbe) Step 2: The cell produces antibodies to “fit” the antigen Producing antibodies 22/03/2016 You’re going down Step 1: The white blood cell detects the antigen (microbe) Step 2: The cell produces antibodies to “fit” the antigen Step 3: The antibodies fit onto the antigens and cause them to “clump” and make them easier to be engulfed Step 4: The antigens are “eaten” by different white blood cells Fighting disease If microbes do enter our body they need to be neutralised or killed. This is done by WHITE BLOOD CELLS: White blood cells do 3 things: 3) They produce antitoxins to neutralise the poisons produced by microbes https://www.youtube.com/watch?v=Bf2t8n1ib wQ 22/03/2016 Key points 22/03/2016 • the pathogens are not the disease they cause the disease • white blood cells do not eat the pathogens - they ingest them • antibodies and antitoxins are not living things - they are specialised protein Fighting disease NATURAL IMMUNITY This is when antibodies are produced by a person when needed or they are passed on by the mother during pregnancy. (breast milk) ARTIFICIAL IMMUNITY A vaccine with dead microbes is injected – the body is “tricked” into producing antibodies ready for the real thing. This is called PASSIVE IMMUNISATION 22/03/2016 22/03/2016 Vaccinations AIM: Explain how vaccinations work . A vaccine is an injection of a dead; weak or a part of a micro organism that stimulates the white blood cells to produce antibodies. How do vaccinations work ? Vaccinations kick-start your white blood cells into making antibodies so you become immune to a disease without catching it. Immune- not effected by/protected from. Small amounts of dead or weakened forms of MO’s injected. White blood cells recognise MO’s White blood cells makes antibodies, which attach to antigens and clump the MO’s together. White blood cells makes another white blood cell and a memory cell Different type of white blood cell digests the clump of MO’s Phatgocytosis. If the real MO invades the memory cell remembers and makes more white blood cells with the right type of antibody. Using Antibiotics 22/03/2016 Antibiotics can be used to kill bacteria. However, there are two problems: 1) Overuse of antibiotics can lead to bacteria becoming resistant to that antibiotiv 2) Antibiotics have no effect on a virus, like the common cold. A virus must be allowed to “run its course”. 22/03/2016 Read page 48 and answer questions How do we prevent microbes destroying our food? 22/03/2016 Quick quiz 22/03/2016 1. Which is the smallest type of microbe and give an example of a disease it can cause. 2. How fast can bacteria reproduce? 3. Give 3 uses for microbes 4. Give the 2 equations for anaerobic respiration 5. Give 4 ways to protect food from microbes. 6. What 7 processes does MRS GREN represent? Anti bacterials 22/03/2016 Microbes grow everywhere which can cause problems. They can cause food to spoil and ___, they can ______ cuts and scrapes, they get into open wounds and cause infections and _______. In order to remove ________, anti bacterials are often used. For example, ______, Savlon, TCP and tea tree oil are all anti bacterial agents. Alternative methods are to heat up an item to a ____ temperature for long enough to ____ the microbes. Bleach, rot, kill, high, microbes, infect, disease. Microbes 22/03/2016 Microbes are micro organisms that are too small to be seen. A pathogen is a microbe that can cause diseases if it enters the body: They can be breathed in through the mouth or nose …or other natural openings… They can be ingested (eaten) through the mouth They can enter through cuts or bites in the skin or just by touching something Microbes: our defence against them 22/03/2016 Our bodies have many defence mechanisms against invading microbes: The skin acts as a barrier Stomach produces stomach acid If our skin is cut platelets seal the wound by clotting Tears contain an enzyme that kills bacteria The breathing organs produce mucus to cover the lining of these organs and trap the microbes