Kaan Yücel M.D., Ph.D. 20.March.2012 Tuesday Enlargement of Axillary Lymph Nodes Lymphangitis (inflammation of lymphatic vessels) Cause: An infection in the upper limb Humeral group – first to be involved Enlargement of Axillary Lymph Nodes Metastatic cancer of the apical group adhere to axillary vein excision of part of the axillary vein Enlargement of the apical nodes obstruction of the cephalic vein superior to pectoralis minor Enlargement of Axillary Lymph Nodes Arterial Innervation and Raynaud’s Disease o The arteries of the upper limb are innervated by sympathetic nerves through the brachial plexus. o Vasospastic diseases involving digital arterioles, such as Raynaud’s disease, may require a cervicodorsal preganglionic sympathectomy to prevent necrosis of the fingers. o The operation is followed by arterial vasodilatation, with consequent increased blood flow to the upper limb. Aneurysm of Axillary Artery The first part of the axillary artery may enlarge (aneurysm of the axillary artery) and compress the trunks of the brachial plexus, causing pain and anesthesia (loss of sensation) in the areas of the skin supplied by the affected nerves. Spontaneous Thrombosis of the Axillary Vein Spontaneous thrombosis of the axillary vein occasionally occurs after excessive and unaccustomed movements of the arm at the shoulder joint. Dermatomes and Cutaneous Nerves of the Upper Limb Checking the integrity of the spinal cord segments on the skin Dermatome: Skin area supplied by a spinal segment C3-C6 lateral margin of the limb C7 middle finger C8-T2 medial margin of the limb Shoulder Pain The skin over the point of the shoulder and halfway down the lateral surface of the deltoid muscle is supplied by the supraclavicular nerves (C3 and 4) The afferent stimuli reach the spinal cord via the phrenic nerves (C3, 4, and 5). Differential diagnosis time Inflammatory lesions involving the diaphragmatic pleura or peritoneum Pleurisy Peritonitis Subphrenic abscess Gallbladder disease Complete lesions involving all the roots of the plexus are rare. Incomplete injuries are common and are usually caused by traction or pressure; individual nerves can be divided by stab wounds. Upper Lesions of the Brachial Plexus (Erb-Duchenne Palsy) Excessive displacement of the head to the opposite side & depression of the shoulder on the same side. Result-Excessive traction or even tearing of C5 and 6 roots Infants during a difficult delivery In adults after a blow to or fall on the shoulder The actor Martin Sheen, however, is on record as mentioning a birth accident in which forceps "mangled" his shoulder. shoulder dystocia Nerves derived from C5 & C6 roots affected Suprascapular nerve Nerve to the subclavius MusculocutaneousMuscles nerve Axillary nerve paralyzed • • • • • • • • Supraspinatus (abductor of the shoulder) Infraspinatus (lateral rotator of the shoulder) Subclavius (depresses the clavicle) Biceps brachii (supinator of the forearm, flexor of the elbow, weak flexor of the shoulder) Greater part of the brachialis (flexor of the elbow) Coracobrachialis (flexor of the shoulder) Deltoid (abductor of the shoulder) Teres minor (lateral rotator of the shoulder) Limb hanging by the side Medially rotated [unopposed sternocostal part of pectoralis major] Forearm pronated loss of biceps brachii action Waiter’s tip position Loss of sensation down the lateral side of the arm Lower Lesions of the Brachial Plexus (Klumpke Palsy) Usually traction injuries caused by excessive abduction of the arm First thoracic nerve Median & ulnar nerves Hand- Clawed appearance Hyperextension of metacarpophalangeal joints Flexion of interphalangeal joints Loss of sensation medial side of the arm C8 nerve damaged, medial side of the forearm, hand, and medial two fingers. Long Thoracic Nerve Injuries Serratus anterior muscle Blows to or pressure on the posterior triangle of the neck During the surgical procedure of radical mastectomy Difficulty in raising the arm above the head. Winged scapula The vertebral border & inferior angle of the scapula will no longer be kept closely applied to the chest wall and will protrude posteriorly Axillary Nerve Injuries Posterior cord of the brachial plexus (C5 & 6) Pressure of a badly adjusted crutch pressing upward into the armpit Vulnerable @ quadrangular space Downward displacement of the humeral head in shoulder dislocations Fractures of the surgical neck of the humerus Axillary Nerve Injuries Deltoid & teres minor paralysis Loss of skin sensation over the lower half of the deltoid muscle Radial Nerve Injuries @Axilla • Badly fitting crutch pressing up into the armpit • Drunkard falling asleep with one arm over the back of a chair • Fractures and dislocations of the proximal end of the humerus Motor Triceps,anconeus, extensors of the wrist paralyzyed No extension of elbow, wrist & fingers Wristdrop- flexion of the wrist Supination ok intact biceps brachii (musculocutaneous nerve) Radial Nerve Injuries @ Axilla Sensory A small loss of skin sensation Down posterior surface of lower part of the arm Down a narrow strip on the back of the forearm Variable area of sensory loss on the lateral part of the dorsum of the hand &on the dorsal surface of the roots of the lateral 3 ½ fingers. Area of total anesthesia relatively small because of the overlap of sensory innervation by adjacent nerves Radial Nerve Injuries @ Spiral Groove of Humerus Fracture of the shaft of the humerus The pressure of the back of the arm on the edge of the operating table Most common@ distal part of the groove Motor Wristdrop Sensory Variable small area of anesthesia over the dorsal surface of the hand & dorsal surface of the roots of 3 ½ fingers Radial Tunnel Syndrome o Tenderness & pain the forearm just below the elbow oWatch out for lateral epicondylitis (tennis elbow) o Differential diagnosis made on history & physical exam oThe difference between these two conditions: where the elbow is most tender oLateral to the elbow the radial nerve travels below the supinator muscle Tennis Elbow (Lateral epicondiylitis) o Small area of chronic pain @ lateral elbow o Pain on wrist extension, pain when shaking hands, weakened grip o More common 30 -50 yrs of age o Many conditions for the cause; not only tennis o Repeated use of of the forearm extensor muscles extensor carpi radialis brevis lateral epicondyle to 2nd metacarpal Injuries to the Deep Branch of the Radial Nerve Motor nerve to the extensor muscles in the posterior compartment of the forearm Fractures of the proximal end of the radius Dislocation of the radial head No sensory loss- Motor nerve Supinator (posterior interosseus nerve continuation of deep branch) & extensor carpi radialis longus (radial nerve) undamaged, and because the latter muscle is powerful, it will keep the wrist joint extended, and wristdrop will not occur. Injuries to the Superficial Radial Nerve Sensory As in a stab wound; A variable small area of anesthesia over the dorsum of the hand & dorsal surface of the roots of the lateral 3 ½ fingers Musculocutaneous Nerve Injuries o Rarely injured o Protected beneath the biceps brachii muscle o Injured high up in the arm; o Biceps & coracobrachialis paralyzed brachialis muscle is weakened (also supplied by radial nerve). o Flexion of the forearm at the elbow produced by the remainder of the brachialis & flexors of the forearm. Musculocutaneous Nerve Injuries Sensory loss along the lateral side of the forearm lateral cutaneous nerve of the forearm continuation of the musculocutaneous nerve beyond the cubital fossa Median Nerve Injuries Occasionally in the elbow in supracondylar fractures of the humerus Most commonly injured by stab wounds or broken glass proximal to the flexor retinaculum: Here it lies in the interval between the flexor carpi radialis & flexor digitorum superficialis tendons, overlapped by the palmaris longus. Median Nerve Injuries @ the Elbow Motor o Pronator muscles of the forearm o Long flexor muscles of the wrist & fingers paralyzed Exception flexor carpi ulnaris & medial half of flexor digitorum profundus Forearm in supine position; weak wrist flexion accompanied by adduction No flexion @ interphalangeal joints of the index & middle fingers Median Nerve Injuries @ the Elbow Ask the patient to make a fist o Index finger, lesser extent middle finger straight o Ring & little fingers flex o No flexion @ thumb’s terminal phalanx flexor pollicis longus paralysis Thenar eminence flattened thenar muscles wasted Thumb laterally rotated & adducted Hand flattened «ape-like» hand Orator’s hand posture Median Nerve Injuries @ the Elbow Sensory Skin sensation loss Lateral half or less of the palm of the hand Palmar aspect of lateral 3 ½ fingers Vasomotor Changes Warmer & drier skin arteriolar dilatation and absence of sweating resulting from loss of sympathetic control Trophic Changes Dry skin and scaly Nails crack easily Atrophy of the pulp of the fingers Median Nerve Injuries @ the Wrist Motor Thenar muscles paralyzed Thenar eminence flattened Thumb laterally rotated & adducted No opposition of the thumb «ape-like» hand First two lumbricals paralyzed When the patient is asked to make a fist slowly, index & middle fingers tend to lag behind the ring & little fingers. Median Nerve Injuries Perhaps most serious disability of all in median nerve injuries : Loss of ability to oppose the thumb to the other fingers Loss of sensation over the lateral fingers Delicate pincer-like action of the hand is no longer possible. Ulnar Nerve Injuries Most commonly injured at the elbow where it lies behind the medial epicondyle usually associated with fractures of the medial epicondyle Most commonly injured at the wrist where it lies with ulnar artery in front of flexor retinaculum Ulnar Nerve Injuries @ the Elbow Motor Flexor carpi ulnaris & medial half of the flexor digitorum profundus paralyzed ASK YOUR PATIENT TO MAKE A FIST o No observation/thightening of the flexor carpi ulnaris tendon passing to the pisiform bone o No fxn of the profundus tendons No flexion of ring & little fingers’ terminal phalanges Flexion of the wrist joint will result in abduction, owing to paralysis of the flexor carpi ulnaris. Ulnar Nerve Injuries @ the Elbow Medial border of the front of the forearm flattens wasting of underlying ulnaris & profundus muscles Small muscles of the hand paralyzed except thenar muscles & first 2 lumbricals -median nerve- Ulnar Nerve Injuries @ the Elbow Unable to grip a piece of paper placed between the fingers No adduction & abduction of fingers No adduct the thumb Paralyzed adductor pollicis Extensor digitorum abduct fingers to a small extent, when metacarpophalangeal joints hyperextended FROMENT’S SIGN Ask your patient to grip a piece of paper between the thumb & index finger: S/he does so by strongly contracting flexor pollicis longus & flexing the terminal phalanx Ulnar Nerve Injuries @ the Elbow Metacarpophalangeal joints hyperextended Interphalangeal joints flexed Lumbrical & interosseous muscles paralysis 4th & 5th fingers Ulnar Nerve Injuries @ the Elbow In longstanding cases the hand assumes the characteristic “claw” deformity (Main en griffe). Flattening of the hypothenar eminence Loss of the convex curve to the medial border of the hand Examination of the dorsum of the hand: Hollowing between the metacarpal bones caused by wasting of the dorsal interosseous muscles. Ulnar Nerve Injuries @ the Elbow Sensory Loss of skin sensation o Anterior & posterior surfaces of the medial third of the hand o Medial 1 ½ fingers Vasomotor Changes Warmer and drier skin arteriolar dilatation & absence of sweating resulting from loss of sympathetic control Ulnar Nerve Injuries @ the Wrist Motor Small muscles of the hand-except thenar & first 2 lumbricals Clawhand more obvious flexor digitorum profundus not paralyzed, marked flexion of terminal phalanges Ulnar Nerve Injuries @ the Wrist Sensory Main ulnar nerve & its palmar cutaneous branch usually severed Posterior cutaneous branch, arises from the ulnar nerve trunk about 2.5 in. (6.25 cm) above the pisiform bone usually unaffected Sensory loss confined to o Palmar surface of medial 1/3 of the hand o Medial 1 ½ fingers o Dorsal aspects of middle & distal phalanges of the same fingers Ulnar Nerve Injuries o With ulnar nerve injuries, the higher the lesion is the less obvious is the clawing deformity of the hand. o Unlike median nerve injuries, lesions of the ulnar nerve leave a relatively efficient hand. Sensation over the lateral part of the hand is intact, pincer-like action of the thumb and index finger is reasonably good, although there is some weakness, owing to loss of the adductor pollicis. Quadrangular Space Syndrome Compression of axillary nerve & posterior circumflex humeral artery @ quadrilateral space o Downward displacement of the humeral head in shoulder dislocations o Fractures of the surgical neck of the humerus Deltoid & teres minor paralysis Loss of skin sensation lower half of deltoid muscle Rotator Cuff Tendinitis Stabilizing the shoulder joint Common cause of pain in the shoulder Excessive overhead activity of the upper limb may be the cause of tendinitis, although many cases appear spontaneously. Rotator Cuff Tendinitis Subacromial bursa-Supraspinatus Good for the ease of friction during abduction of the shoulder Subacromial bursitis, supraspinatus tendinitis, or pericapsulitis Characterized by the presence of a spasm of pain in the middle range of abduction, when the diseased area impinges on the acromion. Rupture of the Supraspinatus Tendon o In advanced cases of rotator cuff tendinitis, the necrotic supraspinatus tendon can become calcified or rupture. o Inability to initiate abduction of the arm o However, if the arm is passively assisted for the first 15° of abduction, the deltoid can then take over and complete the movement to a right angle. Communications Between Median & Ulnar Nerves o Important clinically o Even with a complete lesion of the median nerve, some muscles may not be paralyzed. o Erroneous conclusion that the median nerve has not been damaged. Measuring Pulse Rate The common place: o Where radial artery lies on the anterior surface of distal end of the radius, proximal to the wrist, between flexor carpi radialis & brachioradialis tendons. o Here the artery is covered by only fascia and skin. o Anatomical snuff box between extensor pollicus longus & brevis. Venipuncture For straightforward blood tests antecubital vein it may not always be visible, but it is easily palpated. Cephalic vein for short-term intravenous cannula Anatomical snuffbox Why an important clinical region? 1) Palpating the scaphoid bone to asses a fracture – when hand is in ulnar deviation 2) Pulse of the radial artery Anatomical snuffbox Lateral border Abductor pollicis longus & Extensor pollicis brevis tendons Medial border Extensor pollicis longus tendon Floor Scaphoid & trapezium, distal ends of the extensor carpi radialis longus &extensor carpi radialis brevis tendons Radial artery passes via anatomical snuffbox, deep to extensor tendons of the thumb adjacent to scaphoid & trapezium Peripheral mononeuropathy of the upper limb Compression of the median nerve as it passes through the carpal tunnel into wrist Lies immediately beneath palmaris longus tendon and anterior to the flexor tendons Conditions Diabetes mellitus Rheumatoid arthritis Acromegaly Hypothyroidism Pregnancy Tenosynovitis Gradual onset of numbness and tingling in the median nerve distribution of the hand Breast Quadrants For the anatomical location and description of tumors and cysts, the surface of the breast is divided into four quadrants. Mammography o Radiographic examination of the breasts, mammography, is one of the techniques used to detect breast masses. o A carcinoma appears as a large, jagged density in the mammogram. o Surgeons use mammography as a guide when removing breast tumors, cysts, and abscesses. Mastectomy –breast excisionSimple mastectomy Breast is removed down to the retromammary space. Radical mastectomy More extensive surgical procedure Removal of the breast, pectoral muscles, fat, fascia, and as many lymph nodes as possible in the axilla and pectoral region. Gynecomastia Breast hypertrophy in males after puberty Relatively rare (<1%) • Age or drug related • Imbalance between estrogenic and androgenic hormones • A change in the metabolism of sex hormones by the liver Rule out important potential causes, e.g. suprarenal or testicular cancers Polymastia (supernumerary breasts) Only a rudimentary nipple & areola mistaken for a mole (nevus) Polythelia (accessory nipples) Amastia No breast development @ Axillary fossa or anterior abdominal wall Extra breasts along a line from axilla to groin embryonic mammary crest milk line Auscultatory Triangle Site on the back where breath sounds may be most easily heard with a stethoscope Boundaries Latissimus dorsi Trapezius Medial border of the scapula Stiff Neck Levator scapulae connects the neck and shoulder Pain when trying to turn the head to the side where it hurts, often turning the body instead of the neck to look behind Common causes • Turning the head to one side while typing • Long phone calls without a headset • Sleeping without proper pillow support with the neck tilted or rotated • Activities such as vigorous tennis, swimming the crawl stroke