OUTREACH by UNM Pathology ---and--TriCore Reference Labs Presented By: Brian Hjelle, MD, FCAP Medical Director, Genetics and Cytometry Laboratory TriCore Reference Laboratories Int. Chairman, UNM Pathology OUTREACH •Residents/Fellows •TriCore •Hemepath •OMI OUTREACH Pathology Clinical Fellowships Hematopathology Forensic Pathology Cytopath Molecular Genetic Pathology Surgpath Transfusion Medicine Research Fellows Usually about 6 Grad Students Usually 10-12 OUTREACH –resident alumni UNM Department of Pathology •58 faculty members, including 27 MDs 21 PhDs 5 MD-PhDs 5 Others •An MLS (med lab sciences) program Braggin’ Rights •NCI: Comprehensive Cancer Center •Roadmap Initiative/Flow Cytometry •SEER site •33rd highest NIH-funding for Path Depts •T32 Training grant •Office of Medical Investigator •Top-tier residency w/broad training •HTR, microscopy, FISH •TriCore History of TriCore • Created in 1998 • University of New Mexico Hospital Health Sciences Center • Presbyterian Healthcare Services • The Reference Laboratory (TRL) • St. Vincent’s Medical Center (Santa Fe) University of New Mexico Hospital Health Sciences Center • Affiliated with only medical school in New Mexico • Pathologists university employed and faculty at UNM SOM • Diagnostic services • Research • Teaching – medical students and residents; medical technicians • Cancer Center • Level I Trauma Center • Transplant Center TriCore Structure • Independent not-for-profit entity • Sponsors (Presbyterian, University Hospital) comprise Board of Directors • Lab staff to be employed by TriCore • Non-urgent testing consolidated at Core lab • Histology and cytology consolidated at Core lab • Two pathologist groups to be contracted for medical directorship, technical oversight and anatomic path • TriCore-hired CEO and CMO New Building • Consolidated Core lab opened January 2004 • 1,000 TriCore employees at Core lab, in sponsor hospital labs, branch labs, patient draw sites • Service in New Mexico, El Paso, and southern Colorado • National consult service in hemepath, flow cytometry, cytogenetics HISTORY NET REVENUE 1998 - 2007 $100,000,000TriCore ($MM) % YOY Grwth 1998 $29,659,294 1999 $42,984,363 2000 $45,481,206 5.8% 2001 $52,914,181 16.3% 2002 $58,980,552 11.5% 2003 $66,144,265 12.1% 2004 $71,598,294 $50,000,000 2005 $77,182,389 8.2% TriCore ($MM) 7.8% 2006 $87,270,831 13.1% 2007* $95,009,747 8.9% * Jan - Jul Annualized $0 1998 1999 2000 2001 2002 2003 TriCore ($MM) * Jan - Jul Annualized 2004 2005 2006 2007* Hemepath and Related Services HISTORY TEST VOLUME 1998 - 2007 7,000,000 1998 TOTAL 3,339,192 1999 6,000,000 2000 3,298,736 2001 5,000,000 2002 3,618,912 2003 4,000,000 2004 4,692,155 2005 3,000,000 2006 2007* 2,000,000 5,681,886 3,257,094 3,970,069 5,238,953 5,999,368 6,385,776 1,000,000 0 1998 *Jan-Jul Annualized 1999 2000 2001 2002 2003 2004 2005 2006 2007* Flow Cytometry Case Volume 2003-2006 8000 7000 # of flow cases 6000 5000 4000 3000 2000 1000 0 2003 2004 2005 2006 Consult Case Volume 2000-2007 (projected) 4000 3500 3000 # of Cases 2500 2000 1500 1000 500 0 2000 2001 2002 2003 2004 2005 2006 2007* Total Cytogenetics Tests 2000-2007 (projected) 5000 4500 4000 # of cytogenetics tests 3500 3000 2500 2000 1500 1000 500 0 2000 2001 2002 2003 2004 2005 2006 2007* The Players • M Kathy Foucar, MD – Director of HemePath and Vice Chair for Clinical Affairs • John Hozier, PhD – Pioneering cytogenetics/FISH clinical investigator • Kaari Reichard, MD – Helped initiate FISH service • Mohammad Vasef, MD – Seasoned Molecular Onc, started MolPath fellowship • Carla Wilson, MD, PhD – Established leukemia “template” system for efficiency • Qian Zhang, MD, PhD • Kristin Hunt, MD Office of the Medical Investigator (OMI) New Mexico Office of the Medical Investigator • • • • Centralized, statewide, university-based 8 forensic pathologists 10 central and 130 field investigators Administers University Hospital autopsy service • Trains fellows & pathology residents New Mexico Office of the Medical Investigator • Authorized by legislated state statute • Investigates violent, sudden, suspicious, unexplained & unnatural deaths • Determines: condition of body cause/manner of death • Investigates ~5100 of 14000 deaths/year • Performs ~2100 autopsies/year (>95% of NM autopsies) New Mexico Office of the Medical Investigator • Comprehensive autopsy report & computerized database • Retrospective analyses/prospective coding for epidemiology & research • Organization: statewide populationbased surveillance • UNM tie: consultation/collaboration, enhanced diagnostic accuracy, research Participation in National Surveillance Systems • National Violent Death Reporting System – Conjunction with crime lab, vital records, state health dept., & police agencies – Surveillance & granular epidemiology for all homicides, suicides & unintentional firearm fatalities – CDC funded • Drug Abuse Warning Network – Tracks all substance abuse (licit and illicit) deaths – SAMHSA funded Med-X Surveillance Model for Bioterrorism & ID Mortality • Developed model for Medical Examiner ID surveillance with CDC funding • Uses antemortem symptoms to capture potential cases • Pathology-based syndromic reporting standards • Organism & toxin specific diagnoses – SLD NM Dept of Health – CDC - ID Pathology Activity enhanced diagnostic capacity • Now implemented: NH, OR, MN, GA Nolte KB, et al: Hum Pathol, 38:718-725, 2007 Anthrax Some Summary Comments • We have pioneered in regional laboratory models • We have a model ME office • We have strong leadership in forensic path, hemepath, cancer biology • We have steady growth in hemepath, surgpath, molecular, cytogenetics, FISH, many other areas • Good old fashioned leadership and outreach..