CANCER:COLORECTAL
CASE REPORT:
1. Fadli A, Azmi M, David O, et al. Isolated metacarpal bone metastasis from advanced rectosigmoid carcinoma.
International Medical Journal (IIUM) 2012;11(1):52-62 http://iiumedic.net/imjm/v1/download/Volume%2011%20No%201/IMJM%20Vol11No1-2012-p59-62.pdf.
HEALTH SYSTEMS:
2. Magaji BA, Moy FM, April Camilla R, et al. Health-related quality of life among colorectal cancer patients in
Malaysia: a study protocol. BMC Cancer 2012;12:384-2407-12-384 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443003/.
PUBLIC HEALTH:
3. Rajendra S, Ho JJ. Colonic diverticular disease in a multiracial Asian patient population has an ethnic predilection. Eur J Gastroenterol Hepatol 2005;17(8):871-875.
CLINICAL:
4. Azmi MN, Zailani MA, Norashikin MN, et al. Five-year review of histopathological findings of colorectal cancer patients operated in Hospital Tengku Ampuan Afzan, Kuantan, Pahang, Malaysia. International Medical Journal
(IIUM) 2007;6(1) http://www.e-imj.com/Vol6-No1/Vol6-No1-B3.htm.
HEALTH MANAGEMENT:
5. Mohamed AQ. Consensus/Clinical Practice Guidelines on Screening for Colorectal Cancer in Malaysia.
Malaysian Society of Gastroenterology & Hepatology, College of Surgeons of Malaysia, Academy of Medicine of
Malaysia 2001;.
6. Qureshi MA. Consensus/Clinical Practice Guidelines on Screening for Colorectal Cancer in Malaysia. 2001;.
LAB BASED STUDY – GENETIC EPIDEMIOLOGY:
7. Chew MF, Teoh KH, Cheah PL. CD133 marks for colorectal adenocarcinoma. Malays J Pathol 2012;34(1):25-28 http://www.mjpath.org.my/2012.1/CD133.pdf.
HEALTH SYSTEMS:
8. Sharifa Ezat WP, Natrah MS, Syed Mohd A, et al. Quality of life in Malaysian colorectal cancer patients. Asia
Pac Psychiatry 2013;5 Suppl 1:110-117 http://onlinelibrary.wiley.com/doi/10.1111/appy.12055/pdf.
PUBLIC HEALTH:
9. Loh KW, Hazreen AM, Maznah D, et al. Sociodemographic predictors of recall and recognition of colorectal cancer symptoms and anticipated delay in help- seeking in a multiethnic asian population. Asian Pac J Cancer
Prev 2013;14(6):3799-3804

http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No6/3799-
804%205.19%20Kwong%20Weng%20Loh.pdf.
10. Yunus AG. Surgical management of rectal cancer - no room for error. Malaysian Journal of Medicine and
Health Sciences 2008;4(1):iii-iv http://medic.upm.edu.my/images/stories/journal/VOL4NO1_JANUARY2008.pdf;;.
HEALTH BEHAVIOUR
11. Al-Naggar RA, Bobryshev YV. Knowledge of colorectal cancer screening among young Malaysians. Asian Pac J
Cancer Prev 2013;14(3):1969-1974 http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No3/%201969-
74%202.21%20Redhwan%20A%20Al-Naggar.pdf.
LAB BASED – GENETIC EPID
12. Zahary MN, Ahmad Aizat AA, Gurjeet Kaur, et al. Contribution of the MLH1 -93G>a promoter polymorphism in modulating susceptibility risk in Malaysian colorectal cancer patients. Asian Pac J Cancer Prev 2013;14(2):619-
624 http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No2/619-
624%208.13%20Zahary%20Mohd%20Nizam.pdf.
HEALTH BEHAVIOUR
13. Harmy MY, Norwati D, Norhayati MN, et al. Participation and barriers to colorectal cancer screening in
Malaysia. Asian Pac J Cancer Prev 2012;13(8):3983-3987 http://www.apocpcontrol.org/paper_file/issue_abs/Volume13_No8/3983-
87%207.24%20Harmy%20Mohamed%20Yusof.pdf.
CLINICAL
14. Ulaganathan V, Kandiah M, Zalilah MS, et al. Colorectal cancer and its association with the metabolic syndrome: a Malaysian multi-centric case-control study. Asian Pac J Cancer Prev 2012;13(8):3873-3877 http://www.apocpcontrol.org/paper_file/issue_abs/Volume13_No8/3873-
77%207.16%20Vaidehi%20Ulaganathan.pdf.
LAB BASED
15. Ashwaq Hamid Y, Narazah MY, Imran AK, et al. Pilot study of the sensitivity and specificity of the DNA integrity assay for stool-based detection of colorectal cancer in Malaysian patients. Asian Pac J Cancer Prev
2012;13(5):1869-1872 http://www.apocpcontrol.org/paper_file/issue_abs/Volume13_No5/1869-
72%204.1%20Ashwaq%20Hamid%20Yehya.pdf.

PUBLIC HEALTH:
16. Al-Jashamy K, Murad A, Zeehaida M, et al. Prevalence of colorectal cancer associated with Streptococcus bovis among inflammatory bowel and chronic gastrointestinal tract disease patients. Asian Pac J Cancer Prev
2010;11(6):1765-1768 http://www.apocpcontrol.org/paper_file/issue_abs/Volume11_No6/c%201765-68%2010.20%20Al-
Jashamy%20Karim.pdf.
17. Kong C, April Camilla R, Law C, et al. Impact of socio-economic class on colorectal cancer patient outcomes in
Kuala Lumpur and Kuching, Malaysia. Asian Pac J Cancer Prev 2010;11(4):969-974 http://www.apocpcontrol.org/paper_file/issue_abs/Volume11_No4/c%20969-74%20Kong.pdf.
18. Nor Hayati O, Anani Aila MZ. Association of colorectal carcinoma with metabolic diseases; experience with
138 cases from Kelantan, Malaysia. Asian Pac J Cancer Prev 2008;9(4):747-751 http://www.apocpcontrol.org/paper_file/issue_abs/Volume9_No4/747%20c%20Othman.pdf.
19. Mohd Radzniwan AR, Aznida Firzah AA, Saharuddin A, et al. Colorectal cancer patients in a tertiary referral centre in Malaysia: a five year follow-up review. Asian Pac J Cancer Prev 2009;10(6):1163-1166 http://www.apocpcontrol.org/paper_file/issue_abs/Volume10_No6/1163_c_Rashid.pdf.
20. Mirnalini K, Amutha R, Zalilah MS, et al. Diet and lifestyle intervention among patients with colorectal adenomas: rationale and design of a Malaysian study. Asian Pac J Cancer Prev 2005;6(4):553-560 http://www.apocpcontrol.org/paper_file/issue_abs/Volume6_No4/Mirnalini%20Kandiah.pdf.
HEALTH BEHAVIOUR
21. Husna AA, Loh SY, Low WY, et al. Quality of life of multiethnic adolescents living with a parent with cancer.
Asian Pac J Cancer Prev 2012;13(12):6289-6294 http://www.apocpcontrol.org/paper_file/issue_abs/Volume13_No12/6289-
94%2011.10%20Husna%20A%20Ainuddin.pdf.
HEALTH BEHAVIOUR
22. Afzaninawati Suria Y, Zaleha MI, Shamsul Azhar Shah. Perceptions of Malaysian colorectal cancer patients regarding dietary intake: a qualitative exploration. Asian Pac J Cancer Prev 2013;14(2):1151-1154 http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No2/1151-
54%201.4%20Afzaninawati%20Suria%20Yusof.pdf.
PUBLIC HEALTH
23. Afzaninawati Suria Y, Zaleha MI, Shamsul Azhar Shah. Dietary patterns and risk of colorectal cancer: a systematic review of cohort studies (2000-2011). Asian Pac J Cancer Prev 2012;13(9):4713-4717 http://www.apocpcontrol.org/paper_file/issue_abs/Volume13_No9/4713-
7%208.16%20Afzaninawati%20Suria%20Yusof.pdf.

CLINICAL
24. Syahnaz MH, Khairani O, Tong SF, et al. Factors influencing late consultation among patients with rectal bleeding in University Kebangsaan Malaysia Medical Centre. Asian Pac J Cancer Prev 2010;11(5):1335-1339 http://www.apocpcontrol.org/paper_file/issue_abs/Volume11_No5/c%201335-
39%209.27%20Ismail%20Sagap.pdf.
HEALTH BEHAVIOUR
25. Syahnaz MH, Tong SF, Khairani O, et al. Knowledge of colorectal cancer among patients presenting with rectal bleeding and its association with delay in seeking medical advice. Asian Pac J Cancer Prev
2011;12(8):2007-2011 http://www.apocpcontrol.org/paper_file/issue_abs/Volume12_No8/2007-11%20c7.28%20Hashim.pdf.
CLINICAL
26. Ahmed SA, Rand RH, Layla KM, et al. Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma. BMC Cancer 2009;9:403-2407-9-403 http://www.biomedcentral.com.ezp.imu.edu.my/content/pdf/1471-2407-9-403.pdf.
LAB STUDIES
27. Abdul Aziz AA, Siti Nurfatimah MS, Mohd Aminudin M, et al. Association of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population. Asian Pac J Cancer Prev 2011;12(11):2909-
2913 http://www.apocpcontrol.org/paper_file/issue_abs/Volume12_No11/2909-13%20c10.19%20Aizat.pdf.
CLINICAL
28. Ahmed SA, Rand RH, Fatimah AB. The association of Streptococcus bovis/gallolyticus with colorectal tumors: the nature and the underlying mechanisms of its etiological role. J Exp Clin Cancer Res 2011;30:11-9966-30-11 http://www.jeccr.com/content/pdf/1756-9966-30-11.pdf.
LAB STUDIES
29. Ahmed SA, Rand RH, Fatimah AB. Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-
2, and IL-8. Mol Cancer 2010;9:249-4598-9-249 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946291/pdf/1476-4598-9-249.pdf.
30. Mohamed KA, Abdalrahim FAA, Zeyad DN, et al. Cat's whiskers tea (Orthosiphon stamineus) extract inhibits growth of colon tumor in nude mice and angiogenesis in endothelial cells via suppressing VEGFR phosphorylation. Nutr Cancer 2012;64(1):89-99 http://ezproxy.upm.edu.my:2085/doi/pdf/10.1080/01635581.2012.630160.
31. Balraj P, Ruhana S. PTEN mutation studies in Malaysian colorectal cancer patients. Asia Pacific Journal of
Molecular Biology and Biotechnology 2007;15(1):23-25

http://www.msmbb.org.my/apjmbb/html151/151d.pdf.
32. Fatemeh A, Maznah I, Hosseinkhani H, et al. Effects of CXCR4 siRNA/dextran-spermine nanoparticles on
CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver. Cancer
Manag Res 2011;3:301-309 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173020/pdf/cmr-3-301.pdf.
33. Chandramathi S, Suresh KG, Anita ZB, et al. Attenuation of hydrogen peroxide and ferric reducing/antioxidant power serum levels in colorectal cancer patients with intestinal parasitic infection. Malays
J Med Sci 2009;16(2):15-20 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336169/pdf/mjms-16-2-015.pdf.
34. Lim SR, Gooi BH, Singh M, et al. Analysis of differentially expressed proteins in colorectal cancer using hydroxyapatite column and SDS-PAGE. Appl Biochem Biotechnol 2011;165(5-6):1211-1224.
PUBLIC HEALTH
35. Hilmi I, Goh KL. Commentary: adherence and detection rates in colorectal cancer screening. Aliment
Pharmacol Ther 2013;37(1):156-7; discussion 157-8.
HEALTH BEHAVIOUR
36. Koo JH, Leong RW, Ching J, et al. Knowledge of, attitudes toward, and barriers to participation of colorectal cancer screening tests in the Asia-Pacific region: a multicenter study. Gastrointest Endosc 2012;76(1):126-135.
CLNICAL
37. Wendy L, Radzi M. New registry: National Cancer Patient Registry--Colorectal Cancer. Med J Malaysia
2008;63 Suppl C:57-58.
LAB STUDIES
38. Mirakhorli M, Rahman SA, Abdullah S, et al. Multidrug resistance protein 2 genetic polymorphism and colorectal cancer recurrence in patients receiving adjuvant FOLFOX-4 chemotherapy. Mol Med Rep
2013;7(2):613-617.
39. Ho K, Yazan LS, Ismail N, et al. Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin. Cancer Epidemiol 2009;33(2):155-160.
CLINICAL
40. Tan YM, Rosmawati M, Ranjeev P, et al. Predictive factors by multivariate analysis for colorectal cancer in
Malaysian patients undergoing colonoscopy. J Gastroenterol Hepatol 2002;17(3):281-284.
41. Roslani AC, Abdullah T, Arumugam K. Screening for colorectal neoplasias with fecal occult blood tests: falsepositive impact of non-dietary restriction. Asian Pac J Cancer Prev 2012;13(1):237-241.
42. Ghazali AK, Musa KI, Naing NN, et al. Prognostic factors in patients with colorectal cancer at Hospital
Universiti Sains Malaysia. Asian J Surg 2010;33(3):127-133.
43. Goh KL. Changing trends in gastrointestinal disease in the Asia-Pacific region. J Dig Dis 2007;8(4):179-185.

LAB STUDIES
44. Tan LP, Ng BK, Balraj P, et al. No difference in the occurrence of mismatch repair defects and APC and
CTNNB1 genes mutation in a multi-racial colorectal carcinoma patient cohort. Pathology 2007;39(2):228-234.
45. Yip WK, Choo CW, Leong VC, et al. Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala
Lumpur, Malaysia. APMIS 2013;121(10):954-966.
46. Abdul Murad NA, Othman Z, Khalid M, et al. Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia. Dig Dis Sci 2012;57(11):2863-2872.
47. Davoodi H, Seow HF. Variant Toll-like receptor4 (Asp299Gly and Thr399Ile alleles) and Toll-like receptor2
(Arg753Gln and Arg677Trp alleles) in colorectal cancer. Iran J Allergy Asthma Immunol 2011;10(2):91-99.
48. Zulhabri O, Rahman J, Ismail S, et al. Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer. Singapore Med J 2012;53(1):26-31 http://www.ncbi.nlm.nih.gov/pubmed/22252179.
49. Yam YY, Hoh BP, Othman NH, et al. Somatic copy-neutral loss of heterozygosity and copy number abnormalities in Malaysian sporadic colorectal carcinoma patients. Genet Mol Res 2013;12(1):319-327.
50. Ching-Shian Leong V, Jabal MF, Leong PP, et al. PIK3CA gene mutations in breast carcinoma in Malaysian patients. Cancer Genet Cytogenet 2008;187(2):74-79.
HEALTH BEHAVIOUR
51. Harmy MY, Norwati D, Noor NM, et al. Knowledge and attitude of colorectal cancer screening among moderate risk patients in West Malaysia. Asian Pac J Cancer Prev 2011;12(8):1957-1960.
52. Hilmi I, Hartono JL, Goh K. Negative perception in those at highest risk--potential challenges in colorectal cancer screening in an urban asian population. Asian Pac J Cancer Prev 2010;11(3):815-822.
CLINICAL
53. Gul YA. Management of colorectal cancer--can we do better? Med J Malaysia 2008;63(2):89-90 http://www.e-mjm.org/2008/v63n2/Colorectal_Cancer.pdf.
LAB STUDIES
54. Chandramathi S, Suresh K, Anita ZB, et al. Infections of Blastocystis hominis and microsporidia in cancer patients: are they opportunistic? Trans R Soc Trop Med Hyg 2012;106(4):267-269.
CLINICAL
55. Kamil M, Haron M, Yosuff N, et al. High frequency of hand foot syndrome with capecitabine. J Coll Physicians
Surg Pak 2010;20(6):421-422.
CASE REPORT
56. Ng CV. Hypersensitivity reactions to oxaliplatin in two asian patients. Ann Pharmacother 2005;39(6):1114-
1118.

CLINICAL
57. Dranitsaris G, Truter I, Lubbe MS. The development of a value based pricing index for new drugs in metastatic colorectal cancer. Eur J Cancer 2011;47(9):1299-1304.
LAB STUDIES
58. Tan BS, Tiong KH, Muruhadas A, et al. CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5fluorobenzothiazole (GW-610, NSC 721648) sensitivity in breast and colorectal cancer cells. Mol Cancer Ther
2011;10(10):1982-1992.
CLINICAL
59. Amutha R, Mirnalini K. Food intake and colorectal adenomas: a case-control study in Malaysia. Asian Pac J
Cancer Prev 2009;10(5):925-932 http://www.apocpcontrol.org/paper_file/issue_abs/Volume10_No5/925%20Ramadas.pdf.
LAB STUDIES
60. Khor TO, Gul YA, Ithnin H, et al. Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma. Cancer Lett 2004;210(2):139-
150.
61. Khor TO, Gul YA, Ithnin H, et al. A comparative study of the expression of Wnt-1, WISP-1, survivin and cyclin-
D1 in colorectal carcinoma. Int J Colorectal Dis 2006;21(4):291-300.
62. Chan KH, Chandramathi S, Suresh K, et al. Effects of symptomatic and asymptomatic isolates of Blastocystis hominis on colorectal cancer cell line, HCT116. Parasitol Res 2012;110(6):2475-2480.
63. Chandramathi S, Suresh K, Kuppusamy UR. Solubilized antigen of Blastocystis hominis facilitates the growth of human colorectal cancer cells, HCT116. Parasitol Res 2010;106(4):941-945.
64. Jada SR, Lim R, Wong CI, et al. Role of UGT1A1*6, UGT1A1*28 and ABCG2 c.421C>A polymorphisms in irinotecan-induced neutropenia in Asian cancer patients. Cancer Sci 2007;98(9):1461-1467.
65. Yaacob NS, Darus HM, Norazmi MN. Modulation of cell growth and PPARgamma expression in human colorectal cancer cell lines by ciglitazone. Exp Toxicol Pathol 2008;60(6):505-512.
CLINICAL
66. Hilmi I, Goh KL. Chemoprevention of colorectal cancer with nonsteroidal anti-inflammatory drugs. Chin J Dig
Dis 2006;7(1):1-6.
LAB STUDIES
67. Hong SK, Gul YA, Ithnin H, et al. Expression of beta-catenin, COX-2 and iNOS in colorectal cancer: relevance of COX-2 adn iNOS inhibitors for treatment in Malaysia. Asian J Surg 2004;27(1):10-17.
CLINICAL
68. Teoh CM, Gunasegaram T, Chan KY, et al. Review of risk factors associated with the anastomosis leakage in anterior resection in Hospital Universiti Kebangsaan Malaysia. Med J Malaysia 2005;60(3):275-280 http://www.e-mjm.org/2005/v60n3/Anastomosis_Leakage.pdf.

LAB STUDIES
69. Naik VR, Jaafar H, Seng CE. Lymphatic channel density in colorectal adenocarcinoma. Indian J Pathol
Microbiol 2010;53(1):12-14.
CLINICAL
70. bin Sabir Husin Athar PP, bte Ahmad Norhan N, bin Saim L, et al. Metastasis to the sinonasal tract from sigmoid colon adenocarcinoma. Ann Acad Med Singapore 2008;37(9):788-783.
LAB STUDIES
71. Rajendra S, Ho JJ, Arokiasamy J. Risk of colorectal adenomas in a multiethnic Asian patient population: race does not matter. J Gastroenterol Hepatol 2005;20(1):51-55.
72. Goh KS, Ong TA, Peh SC, et al. P53 expression in colorectal carcinoma: the University of Malaya Medical
Centre's experience. Med J Malaysia 2004;59(4):515-521 http://www.e-mjm.org/2004/v59n4/Colorectal_Carcinoma.pdf.
HEALTH BEHAVIOUR
73. Natrah MS, Ezat S, Syed MA, et al. Quality of life in Malaysian colorectal cancer patients: a preliminary result.
Asian Pac J Cancer Prev 2012;13(3):957-962.
CLINICAL
74. Mahadeva S, Rembacken BJ. Standard "inject and cut" endoscopic mucosal resection technique is practical and effective in the management of superficial colorectal neoplasms. Surg Endosc 2009;23(2):417-422.
LAB STUDIES
75. Chandramathi S, Suresh K, Anita ZB, et al. Comparative assessment of urinary oxidative indices in breast and colorectal cancer patients. J Cancer Res Clin Oncol 2009;135(2):319-323.
CLINICAL
76. Primrose JN. Managing liver metastases: myth or reality? Med J Malaysia 2005;60 Suppl B:67-69.
77. Chan SH, Ng C, Looi LM. Intraoperative methylene blue sentinel lymph node mapping in colorectal cancer.
ANZ J Surg 2008;78(9):775-779.
LAB STUDIES
78. Chan TH, Goh KL. Appropriateness of colonoscopy using the ASGE guidelines: experience in a large Asian hospital. Chin J Dig Dis 2006;7(1):24-32.
79. Lim MS, Melich G, Min BS. Robotic single-incision anterior resection for sigmoid colon cancer: access port creation and operative technique. Surg Endosc 2013;27(3):1021-012-2549-0. Epub 2012 Oct 10.
CLINICAL
80. Cheong KL, Roohi S, Jarmin R, et al. The yield for colorectal cancer and adenoma by indication at colonoscopy. Med J Malaysia 2000;55(4):464-466 http://www.e-mjm.org/2000/v55n4/Colonoscopy.pdf.

LAB STUDIES
81. Lim SR, Gooi BH, Gam LH. Identification of low abundance proteins in colorectal cancer tissues. Cancer
Biomark 2012;12(4):185-198.
HEALTH BEHAVIOUR
82. Goh KL, Quek KF, Yeo GT, et al. Colorectal cancer in Asians: a demographic and anatomic survey in Malaysian patients undergoing colonoscopy. Aliment Pharmacol Ther 2005;22(9):859-864.
LAB STUDIES
83. Aisha AF, Abu-Salah KM, Ismail Z, et al. alpha-Mangostin enhances betulinic acid cytotoxicity and inhibits cisplatin cytotoxicity on HCT 116 colorectal carcinoma cells. Molecules 2012;17(3):2939-2954.
84. Nassar ZD, Aisha AF, Idris N, et al. Koetjapic acid, a natural triterpenoid, induces apoptosis in colon cancer cells. Oncol Rep 2012;27(3):727-733.
85. Ashok Kumar P, Norhaizan ME. Dietary non-nutritive factors in targeting of regulatory molecules in colorectal cancer: an update. Asian Pac J Cancer Prev 2013;14(10):5543-5552 http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No10/5543-
5552%207.25%20Ashok%20Kumar%20Pandurangan%20%28REVIEW%29.pdf.
86. Leong BD, Ramu P, Kumar VM, et al. Synchronous adenocarcinoma of caecum, transverse colon and jejunum. Med J Malaysia 2008;63(2):148-149 http://www.e-mjm.org/2008/v63n2/Synchronous_Adenocarcinoma.pdf.
87. Rajendra S, Kutty K, Karim N. Flat colonic adenomas in Malaysia: fact or fancy? J Gastroenterol Hepatol
2003;18(6):701-704.
88. Tan LP, Ng BK, Balraj P, et al. Gene symbol: APC. Disease: colorectal cancer. Hum Genet 2005;118(3-4):545.
89. Venkatesh RN, Jaafar H, Mutum SS. Heterotopic ossification in skeletal muscle metastasis from colonic adenocarcinoma--a case report. Malays J Pathol 2005;27(2):119-121 http://www.mjpath.org.my/past_issue/MJP2005.2/08Heteropic.pdf.
CLINICAL
90. Harris Ngow A, Wan Khairina W. Cardiac mass in a patient with sigmoid adenocarcinoma: a metastasis?
Cardiovasc J Afr 2012;23(7):e10-e12 http://search.ebscohost.com/login.aspx?direct=true&db=mdc&AN=22915057&site=ehost-live.
CASE REPORT
91. Chan KY, Teoh CM, Sukumar N. Chylous ascites after anterior resection for rectal carcinoma: a rare but significant incident. Asian J Surg 2006;29(1):46-48.
LAB STUDIES

92. Hisham RB, Thuaibah H, Gul YA. Mucinous adenocarcinoma of the rectum with breast and ocular metastases. Asian J Surg 2006;29(2):95-97.
CASE REPORT
93. Jasman J, Mayuha R, Imtiaz H, et al. Subcutaneous metastases from rectal carcinoma: A case report. Journal of Surgical Academia 2011;1(2):23 http://journalarticle.ukm.my/2960/1/23-24.pdf.
CLINICAL
94. Law CW, Roslani AC, Ng LL. Treatment delay in rectal cancer. Med J Malaysia 2009;64(2):163-165.
95. Lee WC, Mastura MY, Lau FN, et al. Preoperative long course chemoirradiation in a developing country for rectal carcinoma: Kuala Lumpur Hospital experience. Asian Pac J Cancer Prev 2013;14(6):3941-3944 http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No6/3941-
44%205.27%20Wei%20Ching%20Lee.pdf.
CASE REPORT
96. Ramanathan Y, Rajagopalan R, Rahman NA. Laryngeal metastasis from a rectal carcinoma. Ear Nose Throat J
2007;86(11):685-686.
LAB STUDIES
97. Siti Aisyah AG, Maznah I, Latifah SY, et al. Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon
Dioxide Fluid Extraction towards Human Colorectal Cancer (HT29) Cell Lines. Evid Based Complement Alternat
Med 2013;2013:549705 http://www.hindawi.com/journals/ecam/2013/549705/.
98. Al-Joudi FS. Prognostic value of an index for serum globulin compensation in colon and breast cancers.
Singapore Med J 2005;46(12):710-713 http://www.sma.org.sg/smj/4612/4612a5.pdf.
99. Nazri A, Lio P. Investigating meta-approaches for reconstructing gene networks in a mammalian cellular context. PLoS One 2012;7(1):e28713 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253778/.
100. Ahmad Aizat AA, Siti Nurfatimah MS, Aminudin MM, et al. XPC Lys939Gln polymorphism, smoking and risk of sporadic colorectal cancer among Malaysians. World J Gastroenterol 2013;19(23):3623-3628 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691041/.
CLINICAL
101. Chan KK, Dassanayake B, Deen R, et al. Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: analysis of survival and prognostic markers. World J Surg Oncol 2010;8:82-7819-8-82

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954852/.
LAB STUDIES
102. Ho KL, Chong PP, Yazan LS, et al. Vanillin differentially affects azoxymethane-injected rat colon carcinogenesis and gene expression. J Med Food 2012;15(12):1096-1102 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523249/.
103. Kaur G, Masoud A, Raihan N, et al. Mismatch repair genes expression defects & association with clinicopathological characteristics in colorectal carcinoma. Indian J Med Res 2011;134:186-192 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181019/.
104. Liong MT. Roles of probiotics and prebiotics in colon cancer prevention: Postulated mechanisms and in-vivo evidence. Int J Mol Sci 2008;9(5):854-863 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635701/.
105. Mustapha MA, Shahpudin SN, Aziz AA, et al. Risk modification of colorectal cancer susceptibility by interleukin-8 -251T>A polymorphism in Malaysians. World J Gastroenterol 2012;18(21):2668-2673 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370004/.
CLINICAL
106. Safari A, Shariff ZM, Kandiah M, et al. Dietary patterns and risk of colorectal cancer in Tehran Province: a case-control study. BMC Public Health 2013;13:222-2458-13-222 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605096/.
LAB STUDIES
107. Wasito I, Hashim SZ, Sukmaningrum S. Iterative local Gaussian clustering for expressed genes identification linked to malignancy of human colorectal carcinoma. Bioinformation 2007;2(5):175-181 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241931/.
108. Wong TW, Colombo G, Sonvico F. Pectin matrix as oral drug delivery vehicle for colon cancer treatment.
AAPS PharmSciTech 2011;12(1):201-214 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066368/.
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