11th Grade Anatomy January 2007 Functions of the Cardiovascular System • Main transportation system of the body. – Transports nourishment from digestion – Transports hormones – Transports red blood cells that carry oxygen – Transports white blood cells that fight disease • Helps regulate body temperature Blood • Blood is considered the fluid of life • A type of connective tissue • The average adult has 5 liters of blood in their body What Makes up Blood? • Fluid = 55% – Plasma • Cells = 45% – Red Blood Cells – White Blood Cells – Platelets What Do They Do? • Plasma – Consist of 90% water – Consists of 10% dry mass •Glucose •Fats •Proteins •Hormones •Vitamins •Minerals What Do They Do? • Red Blood Cells – Also called erythrocytes – Shape is biconcave – They have a protein called hemoglobin which carries oxygen What Do They Do? • White Blood Cells – Also called leukocytes – WBC’s are responsible for the defense of an organism – WBC’s are less numerous – Unlike RBC’s, leukocytes have a nucleus that is used to help identify what type of WBC it is • WBC’s are broken into two categories: – Granulocytes – have granules and a distinclty shapen nucleus •Neutrophil •Eosinophil •Basophil – Lymphocytes – single, large nucleus •Lymphocyte •Monocyte • Platelets – Also called thrombocytes – The main function of platelets is to stop the loss of blood from wounds. Blood Types • There are two chemicals that can be found on the surface of RBC’s: A & B – Type A: has A chemical – Type B: has B chemical – Type AB: has both A & B chemicals • “Universal Acceptor” – Type O: has neither chemical • “Universal Donor” The Heart • The heart is a muscular pump that is located between the lungs. • The heart pumps 7000 liters of blood a day • Humans have a closed circulatory system – meaning that blood is always enclosed by vessels. • The heart is composed of cardiac muscle Heart • The heart is composed of three layers: – Endocardium – Myocardium – Epicardium • The heart is divided into four hollow chambers: 2 on the left & 2 on the right – Right Atrium and Right Ventricle – Left Atrium and Left Ventricle Anatomy of the Heart Blood Flow • Deoxygenated blood enters the heart into the right atrium from two large veins: – Superior Vena Cava – Inferior Vena Cava • From the right atrium the blood will flow into the right ventricle. The valve that separates these two is called the tricuspid valve. This valve prevents blood from going back into the right atrium. • From the right ventricle the blood will exit the heart through the pulmonary valve into the pulmonary arteries into the lungs. • Once the blood is in the lungs it becomes oxygenated and will return back to the heart though the pulmonary veins. • Each lung has two pulmonary veins that bring blood to the left atrium. • Blood exits the left atrium and passes through the mitral valve, (which is a bicuspid), into the left ventricle. • From the left ventricle blood will pass through the aortic valve into the aorta. • The aortic valve prevents blood from flowing back into the heart. • The aortic arch will then send blood to the rest of the body. – Arteries = away from heart Veins = to heart Heart Actions • Systole- heart contraction • Diastole- heart relaxation • Sinoatrial (SA) and Atrioventricular (AV) Nodes are specialized masses of cells that are responsible for initiating the myocardium of the heart to contract. • This information is passed through the Purkinje Fibers of the heart and cause the heart to contract. Gases are Exchanged in Capillary Beds • Oxygenated blood leaves the heart and returns through this process: – – – – – – Arteries Arterioles Capillaries Venules Veins p. 339 Factors that influence Blood Pressure Stroke volume – the total blood discharged from the left ventricle with each contraction (usually around 70mL) Heart Rate – the rate at which your heart beats. (usually measured at beats/min) Cardiac output = stroke volume x heart rate if stroke volume = 70 ml and heart rate is 72 beats/min CO = 70 x 72 = 5,040 mL/min BP varies with Cardiac Output • If the stroke volume or heart rate increases, the cardiac output will increase. • Blood pressure is directly proportional to cardiac output • Meaning, as CO increase, BP increases • As CO decreases, BP decreases Blood Volume • Blood volume – is the total amount of blood in the vascular system • Blood volume varies depending on age, gender, and weight, but is usually around 5 liters • Blood volume and blood pressure are also directly proportional. As BV increases, BP increases, if BV decreases, BP decreases Peripheral Resistance • Peripheral Resistance – friction between the walls of blood vessels and the blood. • Periphereal resistance is inversely proportional to blood pressure. • This means as the blood vessels get smaller, vasoconstriction, blood pressure increases. • As peripheral resistance decreases, vasodialation, blood pressure decreases Blood Viscosity • Ease at which blood flows. • Blood cells and plasma proteins increase blood viscosity • Blood viscosity is directly proportional, meaning that as viscosity increases, blood pressure increases • As blood viscosity decreases, blood pressure decreases