HIV in Brazil Ana Paula Pfitscher Cavalheiro Infectious Disease Resident at Hospital de Clínicas de Porto Alegre HIV in Brazil • Population:192 million – 85% urban – Life expectancy: 66.7 y – 1/3 poor (family income < 160 €/m) • 1988 Constitution: “Health is a right for all and a obligation of the state” – 1985: Civil society + Government -> the National AIDS Program • 80s: Spread information about STD-AIDS • 1991: AZT free access • 1996: HAART free access • Present: HAART, CD4/VL, genotyping in cases of viral failure, drugs for treatment of HAART side effects HIV in Brazil • HIV – Estimated prevalence: 630,000 people (<1% of adult population) • Half of predicted in the early 90s by the World Bank • AIDS – Prevalence: 0.6% of total population • + 25-49y – Increasing between women, heterosexuals, socially excluded and older than 50 y – 190,580 on HAART treatment • By 2002 ARVs had prevented ~358,000 HIV-related hospitalisations, resulting in a saving of more than US$1.1 billion Source of HIV acquisition HIV in Brazil • HIV test is free of charge and can be done in primary care units, hospitals or and STD/AIDS counseling testing centers – 38% of sexually active population has already been tested at least once – Mean first CD4 (without HAART): 316 • 35% less than 200 • Pregnant women are usually tested for STDs and HIV as part of their regular follow-up – But in 2007 only 62% had been tested for HIV before labour – Recommendation not to breastfeed • Provision of infant formula to all children born from HIV + mothers – Reduction of vertical transmission • 581 in 2004 and 320 in 2006 Brazilian Guideline • When start treatment: • Symptomatics • Asymptomatics – CD4 > 500: no ART – CD4 350-500: ART if • Nephropaty, HCV or HBV coinfection, VL >100.000, > 55y, high risk of CVD, any cancer – CD4 <350: ART • AZT, 3TC, TNF, ddI, ABC • EFZ, NVP • ATV, LOP/r, SQV, /r, DRV , IDV • T20 • Raltegravir • Etravirine HIV in Brazil • Key points of National AIDS Program • Prevention: – promote frank talk about safe sex – focus on condom promotion • Brazil is the world’s largest condom importer buying 1.2 billion in 2009 • state-run factory produces 100 million condoms a year – focus on preventing HIV among sex workers • Treatment: – ARV drugs are provided free to everybody who needs; – aggressive efforts to minimise the cost of ARVs Show that you´ve grown up and know what you want. In this Carnival use condom. Living with AIDS is possible, living with prejudice is not. Thank you! Sources: aids.gov.br, avert.org datasus.gov.br, ioc.fiocruz.br Condoms after 50: Try it!