Fusionless Correction fro Early Onset Scoliosis (EOS)

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Fusionless Correction for Early

Onset Scoliosis (EOS)

Emma Orton

BME 281

What is EOS?

• Diagnosed before the skeletal age of 10

• There is a lateral curve of the spine

• Causes pulmonary problems later in life

• There are three different types

– Infantile Idiopathic- diagnosed between 0 and 3 years old and the patient is otherwise healthy

– Juvenile Idiopathic-diagnosed between 4 and 10 years old

– Congenital-is developed within the first 6 weeks of embryonic formation and is when vertebrae are not formed correctly

[1]

Cobb Angle

[2]

[3]

Possible Treatments

• Braces

• For older patients with a less severe curve

• will not be helpful for patients aged 2-7 years with curves of 50 to 60 degrees

• VECTR

• Vertical prosthetic titanium prosthetic rib

• Pushes ribs apart widening the thorax and straightening the spine

• Dual Growing Rods

• Growing Rods with Magnetic Expansion Control

• Spinal Fusion

• Many other surgical treatments

Why are Fusionless Treatments Better?

• When fusion is used the curve of the spine is improved but growth stops

• Fusionless treatments are important for children especially those under 10

• Children under 5 still have up to 12.5 cm of vertical growth

• Lungs do not fully develop till about 8 years old

• Fusion does work for patients who are fully grown

[4]

Criteria for Dual Growing Rods

The general criteria is:

• Significant potential axial growth remaining

• A deformity that is continuing to progress

• A deformity that is flexible or can be made flexible

Dual Growing Rods: Experiment 1

• 38 patients

• Followed for anywhere between 2 and 7 years

(on average 3.3 years)

• Patients received lengthenings on average every 6.8 months

• The cobb angle decreased from 74 degrees to

38 degrees on average

• There was axial growth (T1-S1)

[5]

Dual Growing Rod: Experiment 2

• 23 patients

• Cobb angle corrected from 82 degrees to 38 degrees on average

• On average 1.24cm per year of axial spinal growth

• Improvement of space in the thorax

• 13 complications with 11 patients

Dual Growing Rod: Experiment 3

• Group 1 had a single rod with a short apical fusion

• Group 2 had only a single rod

• Group 3 had dual rod implantation

• Group 1 had the worst results with 23% correction (6.4cm of axial growth) while group three had the best with 71% correction (12.1 cm of axial growth)

Pros and Con of Dual Growing Rod

Pros

• One of the most efficient ways of treating EOS

• Opens up the thorax preventing many future pulmonary issues

• Continues to allow for growth

Cons

• Each patient must receive an invasive surgery every six months for a span of a few years (usually till age

10 for girls and age 13 for boys)

• This leads to more opportunities to contract some kind of infection

• Very physically and psychologically grueling

Magnetically Controlled Growing Rods

(MCRG)

• Attached in basically the same way as the dual growing rods

• Lengthened during quick follow-ups in the office without any invasive surgery every 3-4 months

• This allows for the curve to be managed until their skeletal structure has matured enough for spinal fusion

• The EOS is then tracked using radiographs

[6]

[7]

MCGR

• This technique is very new in the United

States so not many hospitals are doing it

• The first one was completed in Washington DC on a ten year old boy

• The requirements are a skeletal age of 10 years old or younger and a Cobb angle of 50 degrees or greater

• Approved by the FDA in February of 2014

[8]

MCGR Experiment

Criteria

• Younger than 11 years old

• Major curve of at least 30 degrees

• Radiographic thoracic height (T1-T12) less then 22cm

• No previous spine surgery

• 2 year follow-up

The Experiment

• 12 MCGR patients

• 12 TGR patients

• All paired by gender number of rods, age, curve and type of EOS

[6]

Results

Major Curve Correction

• Very similar with MCGR and TRG patients

• Overall it was 32% and 33%

Spinal Height(T1-S1)

• MCGR- 8.1mm/year

• TGR- 9.7mm/year

• This is not considered significantly different

Throacic Height(T1-T12)

Height before surgery

MCGR

158mm

Height immediately following surgery 186mm

Growth per year

TRG

166mm

189mm

1.5mm/yr 2.3mm/yr

Results

MCRG

• 16 surgeries

• 137 noninvasive lengthenings

• 8 implant related complications

TRG

• 73 surgeries

• 12 for initial implant

• 56 for lengthening

• 11/12 had complications

• 4 surgical site infection and 13 implant related

NOTE: All of these patient were from different facilities so there could be some variations in results

[6]

Discussion of Results

• MCGR-does not allow for the sagittal plane to contour ideally because of where the actuator has to be located

• TRG-May produce better results when solely looking at numbers but when the surgeries and many complications are added in it is not ideal

• It is possible that the MCRG would have had results even more similar or better than the TRG results had there been a longer follow up

(average follow up for TR patients was 1.6 years longer)

References

[1] "Congenital Scoliosis." - Scoliosis Research Society (SRS). N.p., n.d. Web. 22 Sept. 2015. types of scoliosis

[2] "Anatomy of the Spine." Spine Anatomy : Southern Oregon Neurosurgical & Spine Associates,

PC. N.p., n.d. Web. 26 Sept. 2015.

[3] "MD Lingo." MD Lingo. N.p., n.d. Web. 26 Sept. 2015.

[4] Hershman, Staurt H., Justin J. Park, and Baron S. Lonner. "Fusionless Surgery for Scoliosis."

Fusionless Surgery for Scoliosis (2013): n. pag. Web. 22 Sept. 2015.

[5] "Frequently Asked Questions." Growing Spine

Foundation. N.p., n.d. Web. 22 Sept. 2015.

[6] Pawlek, Jeff B., and Growing Spine Study Group. "Traditional Growing Rods Versus

Magnetically Controlled Growing Rods for the Surgical Treatment of Early-Onset Scoliosis: A Case-

Matched 2-Year Study." 2.6 (2014): 493-97. Web.

[7] Controlled Growing Rods Treat Scoliosis in Children." MedGadget. N.p., n.d. Web. 22 Sept.

2015.

[8] Chueng, and Samartzis. "Management of EOS." N.p., n.d. Web.

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