Cell Structure & Function Cell Theory 1. All living things are made of cells 2. Cells are the basic unit of life 3. All cells come from pre-existing cells What do all cells have in common? 1.Genetic information (DNA) 2.Cytoplasm – fluid-filled region between center and cell membrane What do all cells have in common? 3. Cell membrane (plasma membrane) – surrounds cell ◦ Function: regulates what enters and leaves cell 4. Ribosomes – make proteins using instructions from DNA How big is a cell? Animation – Cell Size Surface Area to Volume Ratio •Why are cells so small? •Ratio of surface area to volume • Much greater for small cells •Space is important for cells to receive nutrients, oxygen, and to remove waste •Volume increases faster than surface area as cells grow •Greater volume= more metabolic reactions BUT more difficult to transport wastes and nutrients •The smaller the cell, the more efficient it is to transport materials across it Organisms can be: o Unicellular o Consist of only 1 cell o Multicellular o Consist of multiple cells 2 Basic Cell Types PROKARYOTIC EUKARYOTIC Prokaryotic •Smaller/unicellular •Simple •No organelles •No nucleus •Ex: Bacteria Eukaryotic •Larger-multi or unicellular •More complex •Many organelles • Structures that have a specific function; “miniorgans” •Nucleus – encloses DNA • Control center of the cell Eukaryotic oEx: Plants, animals, fungi, protists oUnicellular eukaryotes = Protists Unicellular Eukaryote Protists Why are protists eukaryotes if they are only made up of ONE cell? Amoeba Paramecium Dinoflagellates Prokaryote vs. Eukaryote -What is different between the two types of cells? Prokaryotes •Simple internal structure •Nucleoid Region (no nucleus) •Flagellum → whiplike tail used for movement Prokaryotes oPili – short projects that help bacteria attach to surfaces oMost primitive organisms Bacteria E. Coli Strepococcus mutans Bacteria Staphylococcus aureus Mycobacterium tuberculosis Cell Organelles and Functions EUKARYOTIC CELLS INTERNAL STRUCTURE Eukaryotes CAN BE SPLIT INTO PLANT AND ANIMAL CELLS Animal Cell Animal Cell Plant cell Nucleus oFunction: Control center of the cell oEukaryotic cells ONLY!!! Nucleus 3 parts: ◦1.Contains DNA ◦A. Chromosome – DNA coiled around proteins called histones ◦Humans contain 46 chromosomes in nucleus of all cells ◦ Exceptions: Red blood cells (no nucleus), sex cells ◦B. Chromatin – uncoiled DNA; DNA usually found in this form Nucleus 2. Nuclear envelope (nuclear membrane) – membrane w/ pores to allow materials in and out of the nucleus 3. Nucleolus – inside the nucleus; makes ribosomes Cytoplasm oOrganelles can be found in the cytoplasm oCytoplasm- portion of the cell outside of the nucleus Endoplasmic Reticulum(ER) Folded membranes attached to nucleus Smooth ER → ◦Not lined with ribosomes ◦Synthesizes lipids ◦Detoxifies chemicals (i.e. liver) Rough ER ◦Lined with ribosomes ◦Function: Modifies proteins that are being transported Ribosomes- made of RNA & protein - Function: Assemble proteins based on instructions from DNA C4U Difference between Rough and smooth ER What are ribosomes? Where can they be found? Golgi apparatus (golgi body) Looks like a flattened stack of pancakes Functions: ◦Receives vesicles (sacs) from the ER and finishes, sorts, and ships protein ◦“Packages protein” One side = receiving; other side = shipping Lysosomes •Lysosome – Function: Contains powerful digestive enzymes •Digests food particles to release nutrients to cell Fun Fact enzyme in lysosome destroys skin between fingers/toes during embryo development Lysosomes ◦“Demolition/cleanup crew” ◦Destroys damaged organelles ◦Ex: neutrophils (WBC) engulf bacteria ◦Produced by the Golgi Peroxisomes • Functions: • Breakdown fatty acids, H2O2 (catalase), synthesis of myelin (for nerve cells) • Produced by the ER • Disease: ALD – caused by peroxisome not functioning properly Inside the cell WORKING AS A TEAM Vacuoles Function: Storage “containers” ◦ store various substances Animals = small and numerous Plants = one large central vacuole ◦ Stores mostly water ◦ Helps with the structure of a plant cell Central Vacuole •Also functions as a large lysosomecontains enzymes which break down materials •Increases turgor pressure (internal cell pressure) Turgor Pressure Cell swells due to influx of water Cell shrinks due to water loss Vacuoles Contractile vacuole → gets rid of excess water; found in some protists ◦Prevents bursting of cell & dilution Energy Organelles CHLOROPLAST •Plants only •Some protists and algae •Function: •Site of photosynthesis •Use sun energy to make food energy Energy Organelles MITOCHONDRIA •All eukaryotes •Function: •Site of cellular respiration •Creates energy for cell (ATP) from food Mitochondria •Contain 2 membranes •Outer membrane •Inner membranefolded up inside the organelle Plant cells ONLY! oCell Wall oFunction: Rigid layer to protect and support cell oKeeps cell from bursting oMade of cellulose (carbohydrate) oChloroplasts – used for photosynthesis oLarge central vacuole Plant Cell Cytoskeleton - network of protein filaments (fibers) that help the cell maintain its shape • Function: Helps with support/internal structure and movement • Like wood and nails of house Cytoskeleton Cytoskeleton • Made up of microfilaments and microtubules Microfilaments ◦Made of solid globular protein called actin ◦Used for movement and supports shape ◦Ex: Muscle contractions Intermediate Filaments ◦Made of fibrous proteins ◦They reinforce cell shape and anchor organelles ◦Ex: Holds nucleus in place Microtubules ◦Hollow tubes of protein called tubulin ◦They often disassemble and reassemble ◦Helps with movement) ◦Ex: lysosome may slide along to reach food ◦Ex: movement of chromosomes when cells divide Movement Both made of microtubules wrapped in membrane Cilia → short and numerous; beat together ◦ Ex: Cells of human windpipe sweep pollen & mucous containing debris from lungs Flagella → few; long and whip-like ◦ Ex: sperm cells Centrioles •Type of microtubule •Function: Organize DNA during cell division •ONLY IN ANIMAL CELLS PLANT BOTH ANIMAL Use these terms to fill in your Venn Diagram Cell membrane Golgi body Rough & smooth ER Mitochondria Nucleus Cytoskeleton Ribosomes Central vacuole Chloroplast Lysosome Centrioles Cell Wall Small vacuoles