Cell Structure and Function Cells Smallest living unit Most are microscopic Discovery of Cells Robert Hooke (mid-1600s) Observed sliver of cork Saw “row of empty boxes” Coined the term cell Cell theory (1839)Theodor Schwann & Matthias Schleiden “ all living things are made of cells” (50 yrs. later) Rudolf Virchow “all cells come from cells” Cell Structure Reflects Function Cellular structures have evolved because of a need for a particular function, for example: Neurons have axons to transfer information to other cells Sperm have whiplike tails to enable them to swim Eggs have large quantities of nutrients to aid early embryonic development Principles of Cell Theory All living things are made of cells Smallest living unit of structure and function of all organisms is the cell All cells arise from preexisting cells (this principle discarded the idea of spontaneous generation) Cells are Small! Characteristics of All Cells A surrounding membrane Protoplasm – cell contents in thick fluid Organelles – structures for cell function Control center with DNA Cell Types Prokaryotic Eukaryotic Prokaryotic Cells First cell type on earth Cell type of Bacteria and Archaea Prokaryotic Cells No membrane bound nucleus Nucleoid = region of DNA concentration Organelles not bound by membranes Eukaryotic Cells Nucleus bound by membrane Include fungi, protists, plant, and animal cells Possess many organelles Protozoan Representative Animal Cell Representative Plant Cell Organelles Cellular machinery Two general kinds Derived from membranes Bacteria-like organelles Bacteria-Like Organelles Derived from symbiotic bacteria Ancient association Endosymbiotic Evolution theory of modern cells from cells & symbiotic bacteria Distinguishing Features of the Two Major Cell Types Prokaryotes Eukaryotes No nucleus; nucleoid Nucleus surrounds genome/DNA Very small (~1-10 m) Larger (~10-1000 m) Few internal membranes Many internal membranes No cytoskeleton Extensive cytoskeleton intracellular filaments Corkscrew flagellum made of a single protein Complex flagella made of >300 proteins! Peptidoglycan cell wall Cellulosic cell walls if present Small ribosomes (70S) Big ribosomes (80S) Homeostasis All organisms must maintain a balance regardless of internal and external conditions This task is controlled by the plasma membrane Plasma Membrane Contains cell contents Double layer of phospholipids & proteins Phospholipids Polar Hydrophylic head Hydrophobic tail Interacts with water Movement Across the Plasma Membrane A few molecules move freely Water, Carbon dioxide, Ammonia, Oxygen Carrier proteins transport some molecules Proteins embedded in lipid bilayer Fluid mosaic model – describes fluid nature of a lipid bilayer with proteins Membrane Proteins 1. Channels or transporters Move molecules in one direction 2. Receptors Recognize certain chemicals Plasma Membrane The plasma membrane serves as the boundary between the cell and its environment Allows specific amount of nutrients to enter and allow waste to exit Characteristics of cell membrane permeable – allows some molecules to enter and keeps others out Selectively Like a screen door Plasma Membrane Made up of two layers of phospholipids Controls what moves into and out of the cell Selectively permeable AKA: Lipid Bilayer, Fluid Mosaic, Cell Membrane Capsule Found on some prokaryotic bacterial cells. Layer that lies outside the cell wall Usually composed of polysaccharides It enhances the ability of bacteria to cause disease (ie. E. coli) Slippery Contains water (protection from desiccation) Helps cells stick to surfaces (other cells) Cell Wall Rigid structure Located outside of plasma membrane Found in plant cells, fungi, some bacteria and protists Provides support and protection Composed of cellulose (carbohydrate) Nucleus Control center of the eukaryotic cell Contains directions to make proteins Chromatin – strands of genetic material (DNA) Nucleolus Structure within the nucleus Produces ribosomes Ribosomes The site of protein synthesis Found in the cytoplasm or on the Endoplasmic Reticulum Cytoplasm Clear, gelatinous fluid inside the cell Helps suspend organelles Endoplasmic Reticulum Site of cellular chemical reactions Series of highly folded membranes Rough Endoplasmic Reticulum – have ribosomes attached Smooth Endoplasmic Reticulum – does not have ribosomes attached Golgi Apparatus AKA: Golgi Body Flattened system of tubular membranes Modifies and packages proteins Sort proteins to be sent to appropriate destination Vacuoles Temporary storage of materials Store food, enzymes, other materials needed by the cell, and waste Plant cells usually have one large vacuole, animal cells usually contain many smaller vacuoles Lysosomes Contain digestive enzymes that digest excess or worn out organelles, food particles, viruses and bacteria Chloroplasts Found in the cells of green plants Organelle that captures light energy and produces food to store for later use Contains chlorophyll – gives plants their green color Mitochondria Organelles that transform energy for the cell Double membrane structure with highly folded inner membrane Cytoskeleton Support structure for the cell Composed of microtubules and microfilaments Helps cell to maintain shape Cilia and Flagella Aid in locomotion or feeding May move the entire cell, or aid in movement of substances across the cell surface Cilia and Flagella video Pseudopodia Means fake or false feet Temporary projections of eukaryotic cells. This is how amoebas move, as well as some cells found in animals, such as white blood cells Pseudopodia extend and contract by the reversible assembly of actin subunits into microfilaments. Filaments near the cell's end interact with myosin which causes contraction. Amoeboid movement More on the Cytoskeleton Mitosis Specific cellular forms Muscle Nerve cells Video link Plant and Animal Cells Animal Cells - Don’t have a cell wall - Contain centrioles - Contain many small vacuoles Plant Cells - Generally larger than animal cells - Have a cell wall - Contain chloroplasts - Have one large central vacuole Critical Thinking : Why are plant and animal cells similar? Identify the Following Cellular Structures Advantages of highly folded Membranes Folded membranes are an advantage to a cell because Cell processes can be more efficient Membranes provide a larger surface area for cell process to take place Remember all cell membranes are made up of phospholipids Examples: folded membranes in organelles like mitochondria Microvilli Endomembrane System The endomembrane system is composed of a number of inter-related membrane sacs within the cytoplasm of the cell Rough and smooth ER, Golgi apparatus, Vessicles, Lysosomes The endomembrane system functions in protein synthesis, protein modification, sorting and transport Animation Inner Life of the Cell Long Version Short Version