MON 4/29 wk-6
OBJECTIVE: 9-10
general/honors
TOPIC: gene mutations
DO NOW: -mutation… A:-permanent change in DNA
ABSENT-daily grade: -12.4 READ-APP/Qs
HANDOUTS:
AGENDA:
-weekly organizer
-13.2 READ Qs
-WK#5 OBJECTIVE QUIZ
-12.4 READ Qs
-12.4 VIDEO: Birth and Death of Genes
COMPLETE & TURN IN:
-GATTACA Qs
-wk #5 ORG/OBJ QUIZ
BEFORE/AFTER SCHOOL:
-DW check—12 materials
WRAP UP: -LIST processes that cause mutations
DW: -13.2 PRE-LAB
DUE: TUES

MON:
-GATTACA Qs
-wk #5 org/OBJ QUIZ
WEEK #5 OBJ QUIZ
WEEK #5 OBJ QUIZ
6- During transcription __________________.
a. DNA is replicated
b. mRNA is produced
c. proteins are synthesized
7-What is the end result of translation?
a. nucleotides form chains to make amino acids
b. mRNA send the message to the ribosomes
c. proteins are created from chains of amino acids
WEEK #5 OBJ QUIZ
8- Which of the following sequences of processes correctly reflects the
central dogma?
a. protein synthesis, transcription, translation
b. transcription, translation, protein synthesis
c. translation, transcription, protein synthesis
WEEK #5 OBJ QUIZ
MATCHING
Match the parts in the diagram with the correct label
____ 9- contains genetic information
____ 10- contains ribose
____ 11- found in nucleus only
a. DNA only
b. RNA only
c. both DNA and RNA
12.4 GENE REGULATIONS and MUTATIONS
WHAT YOU WILL LEARN
-prokaryotic/eukaryotic gene regulation
-types of mutations & results
-mutagens
READING Q’s
1-Like DNA code, the following sentence: “The dog ran”
contains only 3 letter words
-INSERT a “z” after “Th”—rewrite the sentence:
Thz edo gra
-WRITE the sentence again inserting an additional letter
Thz zed ogr
-What happens to the sentences as you add letters?
become nonsense
READING Q’s
2-DESCRIBE point mutation
-single nucleotide/base pair is changed
can cause a genetic disorder
READING Q’s
3-NAME
-what type of mutation occurs when a STOP codon replaces
an amino acid codon
-nonsense mutation
cause translation to terminate early
proteins cannot function normally
READING Q’s
4-EVALUATE
-Would a 3-nucleotide insertion result in a frameshift?
X
 YES  NO
-EXPLAIN
-insertion of a nucleotide shifts an entire 3 code
sequence—shifts amino acid sequence
READING Q’s
5-RECORD
The mRNA sequence/sub A for G
-AUG–AAG–UUU–GGC – ACA – UUG-UAA
READING Q’s
6-COMPLETE table: frameshift / substitution
-substitution
-substitution
-frameshift
READING Q’s
7-EXPLAIN how UV light damages DNA
-links thymines—forms a “kink”
READING Q’s
8-DETERMINE
-what a mutation can do to a body (somatic) cell
-cell death
-cancer cell
READING Q’s
9-DISCUSS why a mutagen can have longer lasting effects
in a sex cell than a body cell
-mutations in sex cells are passed on to their offspring
-mutations in body cells are not inherited