THE ILEUM The ileum is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may be used instead of ileum. The ileum follows the duodenum and jejunum and is separated from the cecum by the ileocecal valve (ICV). In humans, the ileum is about 2–4 m long, and the pH is usually between 7 and 8 (neutral or slightly alkaline). Differences between jejunum and ileum There is no line of demarcation between the jejunum and the ileum. There are, however, subtle differences between the two. The ileum has more fat inside the mesentery than the jejunum The ileum has a mesenteric and an anti-mesenteric vascular supply, while the jejunum has only a mesenteric vasculature BILE Liver in the upper abdomen secretes bile a. Liver detoxifies blood by removing poisonous substances , destroys old red blood cells, converts Hb bilirubin (present in bile), produces bile , produces urea from amino groups and ammonia b. Gall bladder stores bile c. Secreted into small intestine by bile duct RESPONSIBILITY The ileum is responsible for absorption of fats, and bile salts. The pores in the ileum are slightly bigger than those in the jejunum and allow vitamin B12, vitamins dissolved in fatty liquids, electrolytes, bile salts and water to soak through the walls and into the blood stream. Where the ileum joins the large intestine is a valve, called the ileocecal valve, which prevents the back flow of materials into the small intestine. By the time material reaches this point, it has a rather pasty consistency. STRUCTURE OF THE ILEUM The villi increase the surface area of the ileum for the absorption. The villi are finger like projections into the lumen of the gut. The villi increase the available surface area by ten times. The crypts contain the secretory cells of intestinal secretion. Mucosa is a mucus secreting membrane. The circular and longitudinal muscles combine to create the contractions known as peristalsis that maintains the movement of chyme along the alimentary canal. The serosa is a tough outer membrane composed of collagen. DIAGRAMS OF THE ILEUM