Vincent Van Gogh – Skull with Cigarette (1886) 1 Mod. L. middle septum, L, mediastinus, midway 2 3 4 5 6 7 8 Nose is divisible into : External nose Nasal cavity 9 Extends the nasal cavities onto the front of the face Pyramidal in shape 10 External nose has bony & cartilaginous parts. Bones Nasal bones Frontal process of maxilla Nasal part of frontal bone Cartilages Lateral cartilages (paired) Alar cartilages (paired) Septal cartilage (single) 11 uppermost parts of the respiratory tract olfactory receptors separated from: each other by a midline nasal septum oral cavity below by the hard palate cranial cavity above by parts of the frontal, ethmoid, &sphenoid bones. Posteriorly, each nasal cavity communicates with the nasopharynx through two openings choana. 12 Each nasal cavity consists of 3 regions. 1) nasal vestibule internal to the naris 2) respiratory region largest , rich neurovascular supply 3) olfactory region @ apex of each nasal cavity, olfactory receptors 3 2 1 13 the most anterior part of the nasal cavity. Olfaction (sense of smell) Respiration Filtration of the dust in the inspired air Humidification and warming of the inspired air (cooling the internal carotid artery for brain) Reception of the secretions from the paranasal sinuses and nasolacrimal ducts 15 2. PARANASAL SINUSES air filled spaces lying within the bones around the nasal cavity lined by respiratory mucosa. open into the nasal cavities innervated by branches of the trigeminal nerve [V]. 1) 2) 3) 4) Frontal sinuses Ethmoid sinuses Sphenoid sinuses Maxillary sinuses 16 between C3- C6 3. LARYNX organ of phonation (vocalization) continuous below with the trachea above opens into the pharynx immediately posterior & slightly inferior to the tongue Cartilage Muscles Connective tissue 17 Unpaired cartilages 1) Thyroid cartilage (biggest) 2) Cricoid cartilage 3) Epiglottic cartilage Paired cartilages 1) Arytenoid 2) Corniculate 3) Cuneiform 18 largest cartilage of the larynx 2 laminae which fuse anteriorly at the thyroid angle & form laryngeal prominence (Adam’s apple) 19 a ring shaped cartilage, most inferior of the laryngeal cartilages Inferiorly attaches to 1st tracheal ring via cricotracheal ligament. Completely encircles the airway Broad lamina of cricoid cartilage posteriorly Narrower arch of cricoid cartilage anteriorly 20 pyramidal in shape 3 processes Apex (superior) articulation w/corniculate cartilage Vocal process (anterior) vocal ligament attaches here Muscular process (lateral) posterior & lateral crico-arytenoid muscles 21 a leaf-shaped cartilage attached by its stem to the posterior aspect of the thyroid cartilage @ the angle Most superior end is free. 22 corniculate cartilages two small conical cartilages Located on the arytenoid cartilages cuneiform cartilages small cartilages anterior to corniculate cartilages lie in the posterior part of the aryepiglottic fold. 23 . Thyrohyoid membrane Below superior margin of the thyroid cartilage, above hyoid bone lateral thyrohyoid ligament (posterior thickening), triticeal cartilage median thyrohyoid ligament (midline thickening) Hyo-epiglottic ligament from the midline of the epiglottis to the body of hyoid bone Cricotracheal ligament between lower border of cricoid cartilage & upper border of 1st tracheal cartilage 24 . lies under the mucosa of the larynx links together the laryngeal cartilages completes the architectural framework of the laryngeal cavity forms some of the ligaments between the cartilages. 25 . 2 parts 1) lower conus elasticus 2) upper quadrangular membrane 26 Conus elesticus cricothyroid ligament, cricovocal membrane, cricothyroid membrane Free upper margin thickens & forms vocal ligament vocal fold opening between the 2 vocal folds (rima) glottis median cricothyroid ligament anterior midline thickening of conus elasticus Conus elasticus cricothyroid ligament, cricovocal membrane, cricothyroid membrane Each vocal ligament free upper margin attaches to anterior part of inner surface of thyroid cartilage @ thyroid angle posteriorly attach to vocal processes of the arytenoid cartilages. 28 Rima glottis Inspiration Widens Phonation Narrows- 2 vocal fold come together Pitch increases with tensing, decreases by relaxation. Intensity of expiration determines the loudness of sound. 29 . Quadrangular membrane vestibular ligament attached posteriorly arytenoid cartilage anteriorly thyroid angle superior to the attachment of the vocal ligament. free lower margin is thickened lateral margin of epiglottis anterolateral surface 30 . Quadrangular membrane vestibular ligament attached posteriorly arytenoid cartilage anteriorly thyroid angle superior to the attachment of the vocal ligament. 31 tubular architectural support fibro-elastic membrane of the larynx laryngeal cartilages . 32 1) opens into anterior aspect of pharynx just below and posterior to the tongue continuous with the lumen of trachea completely encircled by cricoid cartilage 33 2) oblique and points posterosuperiorly into the pharynx horizontal in position 34 3) can be closed by downward movement of the epiglottis. continuously open 35 vestibular and vocal folds divide into three major regions Vestibule between laryngeal inlet & vestibular folds Middle part between vestibular folds & vocal folds Infraglottic space between the vocal folds & inferior opening of the larynx 36 . Rima glottidis between vocal folds separates middle chamber from infraglottic cavity. base formed by interarytenoid fold @ bottom of interarytenoid notch. 37 EXTRINSIC LARYNGEAL MUSCLES INTRINSIC LARYNGEAL MUSCLES MOVE THE LARYNX AS A WHOLE MOVE THE LARYNGEAL COMPONENTS ALTERING THE LENGTH AND TENSION OF THE VOCAL FOLDS AND THE SIZE AND SHAPE OF THE RIMA GLOTTIDIS 38 *Superior . laryngeal nerve Pulls the thyroid angle anteriorly/inferiorly 39 . pulls the arytenoid cartilages anteriorly, toward the thyroid angle relaxes the vocal ligaments to lower the pitch of the voice. 40 . lateral crico-arytenoid muscles muscular processes vocal processes anterior medial transverse and oblique arytenoid muscles Vibration of vocal ligaments Phonation 41 posterior crico-arytenoid muscles 42 Respiration Quiet: laryngeal inlet, rima glottidis open arytenoid cartilages abducted Forced: rima glottidis widens arytenoid cartilages rotated laterally, vocal folds abducted 43 Effort closure occurs when air is retained in the thoracic cavity to stabilize the trunk increasing intra-abdominal pressure Rima glottidis is completely closed. Completely and forcefully shut the airway 44 Phonation arytenoid cartilages & vocal folds adducted rima glottidis closed Air is forced through the closed rima glottidis Vocal folds vibrate against each other and produce sounds. Tension in the vocal folds adjusted by vocalis & cricothyroid muscles 45 Swallowing Rima glottidis closed. Laryngeal inlet narrowed Larynx moves up & forward – opens the esophagus attached to the posterior aspect of the lamina of cricoid cartilage Epiglottis goes down toward the arytenoid cartilages laryngeal inlet narrowed or closed 46 47 recurrent (inferior) laryngeal nerve 48 . from the inferior end of larynx to the level of T5-T6 Terminates by dividing into right & left main bronchi @ sternal angle. Main bronchi give branches inside the lungs & form bronchial tree. 49 formed of tracheal rings which are incomplete posteriorly Posterior parts of the tracheal rings closed by smooth muscle trachealis muscle. . 50 5. PLEURA covers the pulmonary cavities and external surfaces of the lungs in these cavities visceral pleura invests all surfaces of the lungs parietal pleura lines the pulmonary cavities & thorax’s inner surface 51 Visceral pleura insensitive to pain Parietal pleura extremely sensitive to pain Irritation causes local pain or referred pain projecting to the dermatomes supplied by the same spinal nerve. 52 potential space between the layers of pleura contains a capillary layer of serous pleural fluid lubricates the pleural surfaces allows layers of pleura slide smoothly over each other during respiration. lung surface in contact with thoracic wall lung expands fills with air when thorax expands 53 5. LUNGS organs of respiration lie on either side of the mediastinum surrounded by right & left pleural cavities 54 5. LUNGS Air enters and leaves the lungs via main bronchi branches of trachea Inspired air into close relation with venous blood in pulmonary capillaries. 55 5. LUNGS Apex upper pole 3 surfaces costal, mediastinal and diaphragmatic Root of the lung 2 lobes in the left lung oblique fissure 3 lobes in the right lung horizontal & oblique fissures 56 57 TRACHEOBRONCHIAL TREE sublaryngeal airway Trachea @ superior mediastinum TRUNK OF THE TREE Bifurcation @ sternal angle Main bronchi Right main bronchus & Left main bronchus enter hilum of the lung Branches of the tracheobranchial tree 58 TRACHEOBRONCHIAL TREE Main (primary) bronchus Secondary (lobar) bronchi 2 on the left, 3 on the right . Tertiary (segmental) bronchi 59 BRONCHOPULMONARY SEGMENTS largest subdivisions of a lobe o Pyramidal-shaped segments of the lung apices facing the root of the lung. o Separated from adjacent segments by connective tissue septa. 60 BRONCHOPULMONARY SEGMENTS largest subdivisions of a lobe o Segmental bronchus & Tertiary branch of pulmonary artery o Drained by intersegmental parts of the pulmonary veins 61 BRONCHOPULMONARY SEGMENTS largest subdivisions of a lobe o Named according to the segmental bronchi supplying them. o Usually 18-20 in number o Surgically resectable. 62 tertiary segmental bronchi conducting (lobular) bronchioles end as terminal bronchioles respiratory bronchioles pulmonary alveolus basic structural unit of gas exchange in the lung 63 Branching of the bronchial tree • • • • • • • • • Trachea Principal bronchus Lobar bronchi (secondary bronchi) Segmental bronchi (tertiary bronchi) Terminal bronchiol Respiratory bronchiol Alveolar duct Alveolar sac Alveolus 64 65 root of the lung mediastinal pleura reflects off mediastinum a sleeve-like covering for airway, vessels, nerves, lymphatics which pass between the lung and mediastinum 66 hilum of lung The root of the lung joins medial surface of the lung here! mediastinal pleura continuous with visceral pleura @ hilum of the lung. 67 VASCULATURE OF PLEAURA & LUNGS 1 LUNG 1 pulmonary artery (venous blood) 2 pulmonary veins (arterial blood) Each lobe and segment its own artery Branching of the arteries follow the bronchial tree Terminate as capillaries around the alveols. 68 VASCULATURE OF PLEAURA & LUNGS Veins of the parietal pleura drain into systemic veins mainly through the intercostal veins. 69 BRONCHIAL ARTERIES follow bronchial tree as far as respiratory bronchioles. Left bronchial arteries from thoracic aorta paired Right bronchial artery usually arises from 3rd posterior intercostal artery single artery. 70 BRONCHIAL VEINS Right bronchial vein into azygos vein Left bronchial vein into accessory hemiazygos vein. 71 pulmonary plexuses parasympathetic innervation vagus nerve bronchoconstrictor, vasodilator to the lung vessels, secretomotor to the glands sympathetic sympathetic trunk bronchodilator, vasoconstrictor to the lung vessels, inhibitor to glands parietal pleura intercostal & phrenic nerves 72