Anaerobic Respiration:
“Oxidation without Molecular Oxygen”
(Is this an Oxi(gen)-Moron?)
Fermentation: Anaerobic Respiration
Questions
C6H12O6
ATP
H
Pyruvate
Where does the NAD+ come from?
What would happen if the bucket was empty?
How does the bucket normally stay full?
NADH
Mitochondria:
Oxidative
Phosphorylation
With O2
ATP
NAD+
NAD+
Bucket O’
NAD+
Fermentation: Anaerobic Respiration
Without O2 all that is left is NADH, Pyruvate, and
Glucose with nowhere to go.
C6H12O6
ATP
NADH
H
Mitochondria:
Oxidative
Phosphorylation
With
O2O2
Pyruvate
ATP
NAD
NAD
NAD
Types of Fermentation
1. Lactic Acid
Lactic Acid Fermentation
(Muscle cells, Bacteria)
2. Ethyl Alcohol + CO2
Alcoholic Fermentation
(Bacteria, Yeasts)
3. Acetic Acid (vinegar) + CO2
(Bacteria)
Bucket O’ NADA
Why Cells Do “Fermentation”
1. NADH (energy rich) can be used to
convert pyruvate into another molecule
2. Fermentation allows NADH to
recycle to NAD in order to continue
to make ATP without oxygen
3. ATP can still be made as long as
the pyruvate is “going somewhere”
Lactic Acid Fermentation
Alcohol Fermentation
Slide 3
Catabolism / Anabolism
Metabolic Controls
Allosteric Enzyme
“Metabolism is like a river, when one stream
is blocked the flow must go elsewhere”
Little Known Quotes About Cell Respiration
Match the quotes with the person
3
_____Coach
Buesing
4
_____Hans
Krebs
_____Johnny
Storm
7
5
_____Stimpy
(not Ren)
2
_____Mario
and Luigi
_____Michael
Jackson
8
9
_____
Officer McGruff
6
_____
A. Busch III
_____William
Shakespeare
1
1. “Glucose is really the ultimate tragic hero…. Hamlet would have been proud”
2. “Its hard to save the Princess underground. Not having oxygen for your ETC
is like trying to fix a plugged up sewer”
3. “Your lactic acid is your opponent’s best friend”
4. “My cycle is the cycle of life, and the cycle of death”
5. “Wow!!! My food really does come out my nose”
6. “You will never have a Miller time unless the NADH is invited first”
7. “You think I’m hot now, wait until my mitochondrial membranes start leaking”
8. “They told the Twinkie don’t come around here
Don’t wanna see your face, you better disappear
The fire’s in the Kreb’s, and the enzymes are really clear,
So eat it…..just eat it
Just eat it…eat it
Just eat it…eat it”
9. “Stay away from Coenzyme A, it’s a very bad friend”
Allorsteric Enzyme Review
Feedback Inhibition Review
Slide 5
Slide 5