Psychology Today What my Weekend Told Me…… The Cerebrum Some Sweet You Tube Clips The Human Brain Master Watermark Image: http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif Part I: Lobes, the Cerebral Cortex, and Cortical Regions of the Brain Objectives: • Students will be able to describe the general structure of the Cerebrum and Cerebral Cortex. • Students will be able to identify the Cerebrum, the Lobes of the Brain, the Cerebral Cortex, and its major regions/divisions. • Students will be able to describe the primary functions of the Lobes and the Cortical Regions of the Brain. * The Brain has three main parts… 1. The Cerebrum 2. The Brain Stem 3. The Limbic System •Cerebrum -The largest division of the brain. - Divided into two hemispheres, each of which is divided into four lobes. Cerebrum Cerebrum Cerebellum http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif Cerebral Cortex – The outermost of the cerebrum. Cerebral Cortex Cerebral Cortex http://www.bioon.com/book/biology/whole/image/1/1-6.tif.jpg Cerebral Features: • Gyri – Elevated ridges “winding” around the brain. • Sulci – Small grooves dividing the gyri – Central Sulcus – Divides the Frontal Lobe from the Parietal Lobe • Fissures – Deep grooves, generally dividing large regions/lobes of the brain – Longitudinal Fissure – Divides the two Cerebral Hemispheres – Transverse Fissure – Separates the Cerebrum from the Cerebellum – Sylvian/Lateral Fissure – Divides the Temporal Lobe from the Frontal and Parietal Lobes Gyri (ridge) Sulci (groove) Fissure (deep groove) http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif Specific Sulci/Fissures: Central Sulcus Longitudinal Fissure Sylvian/Lateral Fissure Transverse Fissure http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg http://www.dalbsoutss.eq.edu.au/Sheepbrains_Me/human_brain.gif Lobes of the Brain (4) • • • • Frontal Parietal Occipital Temporal http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg * Note: Occasionally, the Insula is considered the fifth lobe. It is located deep to the Temporal Lobe. Lobes of the Brain - Frontal • The Frontal Lobe – located deep to the Frontal Bone of the skull. • It plays an integral role in the following functions/actions: - Memory Formation - Emotions - Decision Making/Reasoning - Personality (Investigation: Phineas Investigation (PhineasGage) Gage) Modified from: http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg Frontal Lobe - Cortical Regions • Primary Motor Cortex – site involved with controlling movements of the body. Primary Motor Cortex/ Broca’s Area •Broca’s Area – •Controls speech and language comprehension. • Located on Left Frontal Lobe. •Broca’s Aphasia – Results in the ability to comprehend speech, but the decreased motor ability (or inability) to speak and form words. Lobes of the Brain - Parietal Lobe • The Parietal Lobe – located atop the brain behind the frontal lobe . • It plays a major role in the following functions/actions: - Sensory processing center - Spatial awareness and perception (Proprioception - Awareness of body/ body parts in space and in relation to each other) Modified from: http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg Parietal Lobe - Cortical Regions • Somatosensory Cortex – receives messages of touch, temperature, and certain other bodily sensations. Lobes of the Brain – Occipital Lobe • The Occipital Lobe – located deep to the Occipital Bone of the Skull. •function is the interpretation of VISION and visual stimuli. Modified from: http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg Occipital Lobe – Cortical Regions • Primary Visual Cortex – This is the primary area of the brain responsible for sight -recognition of size, color, light, motion, dimensions, etc. Damage to Visual Cortex results in Visual Agnosia • Visual Association Area – Interprets information acquired through the primary visual cortex. Lobes of the Brain – Temporal Lobe • The Temporal Lobes – located on the sides of the brain, deep to the Temporal Bones of the skull. • They play an integral role in the following functions: - Hearing -Organization/Comprehension of language - Information Retrieval (Memory and Memory Formation) Modified from: http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg Temporal Lobe – Cortical Regions • Primary Auditory Cortex – Responsible for hearing • Wernicke’s Area – Language comprehension. Located on the Left Temporal Lobe. - Wernicke’s Aphasia – Language comprehension is inhibited. Words and sentences are not clearly understood, and sentence formation may be inhibited or nonsensical. Match That Brain Function: Word Bank 1 • 1. Stimulates muscle movements • 2. Reward and Pleasure Chemical • 3. Pain control chemical • 4. Inhibitory chemical • 5. Excitatory chemical • 6. Fight or flight associated with anger • 7. Fight or flight associated with fear • 8. Mood regulator “happy chemical” • 9. Circadian Rhythm “sleep chemical” • Arcuate Fasciculus - A white matter tract that connects Broca’s Area and 1 4 Wernicke’s Area through the Temporal, Parietal and Frontal Lobes. Allows for coordinated, comprehensible speech. Damage may result in: - Conduction Aphasia - Where auditory comprehension and speech articulation are preserved, but people find it difficult to repeat heard speech. 2 3 6 5 7 Modified from: http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg Match that Brain Function Word Bank 2 • 1 The Nervous systems central computer • 2. The body’s automatic System • 3. The body’s arousal system • 4. The body’s voluntary movement System • 5. The part that relays info from the body to the brain • 6. The system that includes the brain and spinal cord • 7. The System that includes everything outside the brain and spinal cord • 8. The system that calms the body down The Cerebral Cortex 2 3 1 4 5 6 Broca’s Area 10 7 9 8Wernicke’s Area Match That Brain Part Word Bank 3 • 1. Thinking and Reasoning • 2. Touch and Physical Sensation • 3. Vision • 4. Hearing/Memory • • • • • 5. Grammar 6. Object Recognition 7. Movement 8. Sound formation 9. Language Comprehension • 10. Changes in touch and temperature The Cerebral Cortex Broca’s Area Wernicke’s Area Specialization and Integration • Brain activity when hearing, seeing, and speaking words B. Lobes and Structures of the Brain A. J. I. H. C. G. G. D. E. http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif F. Wernicke’s Aphasia • http://www.youtube.com/wa tch?v=dKTdMV6cOZw&fe ature=related Broca’s Aphasia • http://www.youtube.com/wa tch?v=NUTpel04Nkc&featu re=related Object Agnosia http://www.youtube.com/watch?v =rwQpaHQ0hYw Lobes and Structures of the Brain A Primary Motor Cortex B. Frontal Lobe C. Broca’s Area D. Wernicke’s Area E. Temporal Lobe A. (groove) G. B. F. F. Visual Association Area G. Primary Visual Cortex H. Occipital Lobe I. Parietal Lobe C. (groove) D. E. (groove) J. Somatosensory Cortex http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif Copyright: Gary Larson Q: Assuming this comical situation was factually accurate, what Cortical Region of the brain would these doctors be stimulating? Further Investigation Phineas Gage: Phineas Gage was a railroad worker in the 19th century living in Cavendish, Vermont. One of his jobs was to set off explosive charges in large rock in order to break them into smaller pieces. On one of these instances, the detonation occurred prior to his expectations, resulting in a 42 inch long, 1.2 inch wide, metal rod to be blown right up through his skull and out the top. The rod entered his skull below his left cheek bone and exited after passing through the anterior frontal lobe of his brain. Frontal Remarkably, Gage never lost consciousness, or quickly regained it (there is still some debate), suffered little to no pain, and was awake and alert when he reached a doctor approximately 45 minutes later. He had a normal pulse and normal vision, and following a short period of rest, returned to work several days later. However, he was not unaffected by this accident. http://www.sruweb.com/~walsh/gage5.jpg Learn more about Phineas Gage: http://en.wikipedia.org/wiki/Phineas_Gage Frontal Q: Recalling what you have just learned regarding the frontal lobe, what possible problems or abnormalities may Gage have presented with subsequent to this type of injury (remember the precise location of the rod through his brain)? A: Gage’s personality, reasoning, and capacity to understand and follow social norms had been diminished or destroyed. He illustrated little to no interest in hobbies or other involvements that at one time he cared for greatly. ‘After the accident, Gage became a nasty, vulgar, irresponsible vagrant. His former employer, who regarded him as "the most efficient and capable foreman in their employ previous to his injury," refused to rehire him because he was so different.’ Q: It is suggested that Gage’s injury inspired the development of what at one time was a widely used medical procedure. What might this procedure be, and how does it relate to Gage’s injury? A: The frontal lobotomy. This has been used with the intention to diminish aggression and rage in mental patients, but generally results in drastic personality changes, and an inability to relate socially. This procedure is largely frowned upon today, with the development of neurological drugs as treatments. Frontal Psychology Today A Simple Survey The Amazing Brain Left v Right Beautiful Spinning Lady Did You Know • Your brain is also split into 2 different sides. – Known as your cerebral hemispheres. • It contains your left and right “cerebral hemispheres” or brains • I’m sure you’ve heard before, the left side of the brain controls the right side of your body, while the right side of the brain controls the left side of your body. Our Divided Brain • The information highway from the eyes to the brain If you Didn’t Already Know • The left brain and right brain differ in abilities. – Each ability makes it’s own hemisphere unique. – Without 1 hemisphere we would lack important skills we seem to take for granted. – Each Hemisphere works together to balance one another out – So, who are you? Are you right brainer, or a left brainer? The Glue of It All – Corpus Callosum • thick band of nerve fibers that divides the cerebrum into left and right hemispheres. • It connects the left and right sides of the brain • allowing for communication between both hemispheres. Splitting The Corpus Callosum • What would happen if the corpus callosum were cut in half? • It’s called having split brains – Your left and right brain could work opposite each other because communication would be lost – Think of it like this • What the left brain learns and thinks is unknown to the right brain, and vice versa What Happens When One Is Damaged • Well, think of it this way – If one hemisphere of your brain is damaged, the ability to practice certain skills can be accounted for by the other brain. – Brain damage is rarely ever reparable but possible • If the right brain is damaged, the ability to understand jokes, spatial skills, and simple language comprehension could be lost • If the Left is damaged, higher order thinking such as the use of language, speech, calculations, and rhythm may be lost or destroyed Brain Plasticity Jodi Millerhttp://www.youtube.com/watch?v=rDTiZpPyqRk Damage to the Right Side • Causes Spatial Neglect: ignoring one side of vision of the body after damage to a brain hemisphere. Left Brain v Right Brain The Match of the Century The Left Brain Did You Know • 95% of adults use this side for language(speaking, writing, and understanding) The Left Brain • 3 Man Functions: – Be more Detail Oriented • Uses as much information provided to analyze EVERY part that makes up something – See problems as individual Parts • Left brain people break problems down into smaller parts. This allows a combination of answers to complete the whole – Logic based • Using what is known based on facts and observation to answer questions Characteristics of a Left Brain: Who are You? • Lefts also naturally evaluate • When a new concept is what's wrong and why it won't mentioned, they are likely to say, work. "Why change things? What's wrong with the way we are doing • They tend to not see the whole things?“ person but the flaw(s). • Lefts are skeptical of anything • These are the people that come home from work and get upset new. It can be a new invention, that the furniture has been work schedule, or a new rearranged. appliance. They resist anything new and untried. • They enjoy classical music . Of course, it has a predictable beat • They enjoy math, primarily and rhythm. No surprising because numbers never change syncopation to catch them off and they promote a challenge guard. The Right Brain • Can produce only the simplest language and numbers. The other 5% – Non verbal responses, such as pointing at objects, to answer questions The Right Brain • 3 Main Functions: – Be more creative • “combining multiple parts into one large piece” – See problems as a whole • “rather then analyzing what went wrong, the right brain sees the problem and attempts a solution based on the problem – Less detail oriented • “it doesn’t matter what combines to make up the picture, it’s the picture itself that matters.” See What I Mean? Left Brain Right Brain • • • • • • • • • • • • • • • • • • • • • • • • Uses logic detail oriented facts rule words and language present and past math and science can comprehend knowing knows object name reality based forms strategies Practical safe uses feeling "big picture" oriented imagination rules symbols and images present and future philosophy & religion can "get it" (i.e. meaning) knows object function fantasy based presents possibilities Impetuous risk taking Characteristics of a Right Brain: Who are You? • Rights think and learn in visual, kinesthetic and audio images. • They don't memorize well and need to visualize a picture so they can recall the facts. • When right brains talk to you, they look at you while listening and look away to the left when answering a question. • Right brains embrace new ideas. They are future thinkers and enjoy introducing controversial ideas • They believe that everything is possible, What Happens When One Is Damaged • Well, think of it this way – If one hemisphere of your brain is damaged, the ability to practice certain skills can be accounted for by the other brain. – Brain damage is rarely ever reparable. • If the right brain is damaged, the ability to understand jokes, spatial skills, and simple language comprehension could be lost • If the Left is damaged, higher order thinking such as the use of language, speech, calculations, and rhythm may be lost or destroyed The Corpus Callosum • Allows information from right brain and left brain to be passed to one another. – Both brains do opposite things but work together – It’s like having two brains that communicate and work together • Remember: – The right side of your brain controls the left side of your body – The left side of your brain controls the right side of your body Right Brain – Clockwise Left Brain- Counter clockwise Can you make her switch? Resources Images: • • • • • • http://www.dalbsoutss.eq.edu.au/Sheepbrains_Me/human_brain.gif http://www.bioon.com/book/biology/whole/image/1/1-8.tif.jpg http://www.bioon.com/book/biology/whole/image/1/1-6.tif.jpg http://williamcalvin.com/BrainForAllSeasons/img/bonoboLH-humanLH-viaTWD.gif http://www.math.tu-dresden.de/~belov/brain/motorcor2.gif Larson, Gary. The Far Side. Phineas Gage: • • • • http://www.sruweb.com/~walsh/gage5.jpg http://soma.npa.uiuc.edu/courses/bio303/Image7.jpg http://en.wikipedia.org/wiki/Phineas_Gage http://scienceeducation.nih.gov/nihHTML/ose/snapshots/multimedia/ritn/Gage/Broken_brain1.html History of Studying the Brain • Franz Joseph Gall (1758 – 1828) – Phrenology • The study of the structure of the skull to determine a person’s character and mental capacity • 26 ‘organs’ on the surface of the brain History of Studying the Brain Phrenological Map of the Skull History of Studying the Brain • Flourens (1794 – 1867) – Emphasized the importance of experimental research of the brain – Carefully controlled experiments on animals to determine localities of brain and their functions – Moved the field of brain research into a more scientific arena The Brain • Three main parts – Brain Stem – Limbic System – Cerebral Cortex Areas of the Brain Forebrain/ Cerebrum Midbrain/Limbic System Hind Brain/ Brain Stem The Brain Stem The Brain Stem • Brainstem – the oldest part and central core of the brain, beginning where the spinal cord swells as it enters the skull – responsible for automatic (autonomic nervous system)survival functions • Medulla [muh-DUL-uh] – base of the brainstem – controls heartbeat and breathing The Brain Stem • Thalamus [THAL-uh-muss] – the brain’s sensory switchboard, located on top of the brainstem – it directs messages to the sensory receiving areas in the cortex – Relay center • Filters & organizes information from senses • Pons – Connects the cerebrum to the spinal cord – Transfers messages from brain to spine The Brain Stem • Reticular Formation – Stimulating the sympathetic and parasympathetic branch – Sleep and Attention The Brain Stem • Cerebellum [sehr-uhBELL-um] – the “little brain” attached to the rear of the brainstem – It helps coordinate voluntary movement and balance • From motor cortex to cerebellum to spine to body to body part The Limbic System Limbic System a doughnut-shaped system of neural structures at the border of the brainstem and cerebral hemispheres associated with emotions such as fear and aggression and drives such as those for food and sex includes the hippocampus, amygdala, and hypothalamus. The Limbic System • Amygdala [ah-MIG-dah-la] – two almond-shaped neural clusters – Linked fear, aggression, drive, motivation, guilt – Allows us to recognize emotions in others The Limbic System • Hippocampus – memory forming, organizing, and storing. – connecting emotions and senses, such as smell and sound, to memories. The Limbic System • Hypothalamus – neural structure lying below (hypo) the thalamus – Directs several maintenance activities • eating • drinking • body temperature – helps govern the endocrine system via the pituitary gland – is linked to emotion The Endocrine System • Controls many body functions – exerts control by releasing special chemical substances into the blood called hormones – Hormones affect other endocrine glands or body systems • Derives its name from the fact that various glands release hormones directly into the blood, which in turn transports the hormones to target tissues via ducts. The Endocrine System • Consists of several glands located in various parts of the body. • Pituitary gland: a small gland located on a stalk hanging from the base of the brain • “The Master Gland” – Primary function is to control other glands. – Produces many hormones. – Secretion is controlled by the hypothalamus in the base of the brain. The Endocrine System • The Thyroid Gland – lies in the anterior neck just below the larynyx. – Two lobes, located on either side of the trachea, connected by a narrow band of tissue called the isthmus. – Sacs inside the gland contain colloid • Within the colloid are the thyroid hormones: – thyroxine (T4) – triiodothyronine (T3) • When stimulated (by TSH or by cold), these are released into the circulatory system and the metabolic rate. – “C” cells within the thyroid produce the hormone calcitonin. The Endocrine System • Increased thyroid hormone release causes hyperthyroidism, commonly called Graves’ disease. – Signs and symptoms: • insomnia, fatigue • tachycardia • hypertension • heat intolerance • weight loss – Long term hyperthyroidism: • Exopthalmos – bulging of the eyeballs (picture Barbara Bush) • In severe cases - a medical emergency called thyrotoxicosis can result. The Endocrine System • Parathyroid Glands – small, pea-shaped glands, located in the neck near the thyroid – usually 4 - number can vary – regulate the level of calcium in the body – produce parathyroid hormone - level of calcium in blood – Hypocalcemia can result if parathyroids are removed or destroyed. The Endocrine System • Pancreas – a key gland located in the folds of the duodenum – has both endocrine and exocrine functions – secretes several key digestive enzymes • Islets of Langerhans – specialized tissues in which the endocrine functions of the pancreas occurs – include 3 types of cells: • alpha ( ) • beta () • delta () – each secretes an important hormone. The Endocrine System • Adrenal Glands – 2 small glands that sit atop both kidneys. – Each has 2 divisions, each with different functions. • the Adrenal Medulla secretes the catecholamine hormones norepinephrine and epinephrine (closely related to the sympathetic component of the autonomic nervous system). The Endocrine System • Gonads and Ovaries: – the endocrine glands associated with human reproduction. – Female ovaries produce eggs – Male gonads produce sperm • both have endocrine functions. • Ovaries: – located in the abdominal cavity adjacent to the uterus. – Under the control of LH and FSH from the anterior pituitary they manufacture • estrogen • protesterone The Endocrine System • Estrogen and Progesterone have several functions, including sexual development and preparation of the uterus for implantation of the egg. • Testes: – located in the scrotum – produce sperm for reproduction – manufacture testosterone • promotes male growth and masculinization – Controlled by anterior pituitary hormones FSH and LH.