NATIONAL RESEARCH PROGRAM AW ARDS FOR 2014-2016 CYCLE Granting period 1 July 2014 – 30 June 2016 Researcher Project Title Institution Amount Year 1 Amount Year 2 Total Award Pilot Project Grants Prof. Mohan Babu Mapping the Systems Properties of the Mitochondrial Interactome in Parkinson’s Disease University of Regina $45,000 N/A $45,000 Dr. Eric Dumont Neurophysiological trace of L-DOPA-induced dyskinesia in the bed nucleus of the stria terminalis of 6-OHDA-lesioned rats Queen’s University $45,000 N/A $45,000 Dr. Patrick Flood A novel Anti-Inflammatory Therapeutic Approach to Parkinson's disease University of Alberta $44,101 N/A $44,101 Dr. Jessica Grahn Individual differences in response to auditory cues in Parkinson's disease University of Western Ontario $44,987 N/A $44,987 Dr. Suneil Kalia Inhibition of BAG5 to mitigate alpha-synuclein oligomerization and neurodegeneration in Parkinson's Disease University Health Network $45,000 N/A $45,000 A novel fMRI approach to investigating the pathophysiology of postural instability in Parkinson's Disease University of British Columbia $45,000 N/A $45,000 Porridge for Parkinson’s (Toronto) Pilot Project Grant Dr. Mark Carpenter Pilot Project Grants – Funded by Quebec Research Fund on Parkinson* Dr. Frederic Calon Can exercise and omega-3 fatty acids synergize to restore dopamine neurons in Parkinson’s disease? Laval University $45,000 N/A $45,000 Dr. Francesca Cicchetti Microvesicles: biomarkers and vehicles for the propagation of alpha synuclein Laval University $45,000 N/A $45,000 Dr. Julien Doyon Effects of aerobic exercise training with or without preferred rhythms on learning new motor skills in patients with Parkinson's disease synucleinopathy Montreal Geriatric Institute – University of $44,725 Montreal N/A $44,725 Dr. Ron Postuma Association of Cognitive dysfunction with Orthostatic Hypotension in patients with Parkinson’s disease. The Research Institute of the McGill University $40,620 Health Centre N/A $40,620 Pilot Project Grants – Funded by Quebec Research Fund on Parkinson and Parkinson Society British Columbia Prof. Alex MacKay Assessment of "normal appearing" white matter in Parkinson's disease and its association with cognitive dysfunction University of British Columbia $45,000 N/A $45,000 “She will drive the ___”: Predictive language comprehension in persons with Parkinson disease University of Western Ontario $40,915 N/A $40,915 mGlu2 receptors and psychosis in Parkinson’s disease University of Montreal $44,995 $44,989 $89,984 Targeting mitochondrial defects in an isogenic human stem cell model of Parkinson's Disease University of Guelph $45,000 $45,000 $90,000 Structural basis of PINK1 kinase activation McGill University $45,000 $45,000 $90,000 Pilot Project Grant – Funded by Garden Centre Group Co-op Dr. Ken McRae New Investigator Awards Dr. Phillippe Huot Pedaling for Parkinson’s New Investigator Award Dr. Scott Ryan Dr. Jean-Francois Trempe 1 Fellow Project Title Institution Amount Year 1 Amount Year 2 Total Award Basic Research Fellowships Dr. Kwang-Soo Kim Neurodegeneration, Parkinson's disease, LRRK2, immune system. University of Ottawa $50,000 $50,000 $100,000 Dr. Mattia Volta The role of LRRK2 in the development and transmission of acute alpha-synuclein neuropathology University of British Columbia $50,000 $50,000 $100,000 Basic Research Fellowships - Funded in partnership by Quebec Parkinson Network, Quebec Research Fund on Parkinson’s and Parkinson Society Canada Mr. Alexandru Hanganu Evolution of Mild Cognitive Impairment in Patients with Parkinson's disease Montreal Geriatric Institute – University of Montreal $40,000 $40,000 $80,000 Mr. Omid Tavassoly Molecular Mechanism of Alpha-Synuclein Propagation in Parkinson's disease McGill University $40,000 $40,000 $80,000 Toronto Western Hospital $50,000 N/A $50,000 $50,000 N/A $50,000 Clinical Movement Disorder Fellowship (1 Year) Pedaling for Parkinson’s Clinical Movement Disorders Fellowship Improving Phase IIa clinical studies of new treatments for Parkinson’s disease; using the intravenous levodopa paradigm Dr. Camila Henriques de Aquino Dr. Daryl Wile Student Genetic and Neuroimaging Markers for Parkinson Disease: Correlation with Clinical Phenotype and Outcomes Project Title University of British Columbia Institution Amount Year 1 Amount Year 2 Total Award Graduate Student Awards Miss Leigh Christopher Identifying the role of amyloid deposition in cognitive decline in Parkinson’s disease Centre of Addiction and $15,000 Mental Health $15,000 $30,000 Mr. Paul Cocker Investigating the potential efficacy of Dopamine D4 receptors in alleviating compulsive gambling in Parkinson's Disease. University of British Columbia $15,000 $15,000 $30,000 Miss Nalia Kuhlmann Morphological and electrophysiological investigation of the role of LRRK2 in activitydependent striatal synaptic plasticity. University of British Columbia $15,000 $15,000 $30,000 Graduate Student Awards – Funded by Quebec Parkinson Network Mr. Nadhir Litim Effects of gonadal medications for neuroprotection of the brain in an animal model of Parkinson’s Disease Le Centre Hospitalier Universitaire de Québec $15,000 $15,000 $30,000 Miss Jessica Trung Effects of transcranial magnetic stimulation on the cognitive profile of Parkinson's patients with mild cognitive impairment Montreal Geriatric Institute – University of $15,000 Montreal $15,000 $30,000 University of British Columbia $15,000 $30,000 Graduate Student Award – Funded by Garden Centre Group Co-op Mr. Matthew Sacheli Investigating the therapeutic mechanisms of exercise interventions for the treatment of Parkinson’s disease $15,000 * Quebec Research Fund on Parkinson is funded notably, by the Saucier–van Berkom Parkinson Quebec Research Fund and Parkinson Society Saskatchewan. 2