Period 1 HAP GI NA KIM, JENNA OAK & SALONI SAXENA Function The endocrine system Extracellular communication Uses chemicals (hormones) to regulate body functions Glands Hypothalamus Gland Thymus Gland Location • Thymus gland- behind your sternum and between your lungs • Hypothalamus gland - In the middle of the base of the brain and encapsulates the ventral portion of the third ventricle Roles Thymus gland It ensures that the body is able to distinguish disease organisms from body tissues Hypothalamus Gland Control center for many autonomic functions of the peripheral nervous system Plays a vital role in maintaining homeostasis Hormones Thymus: 1. Thymosin 2. Thymopoietin Hypothalamus: 1. Dopamine 2. Somatostatin Thymosin and Thymopoietin Thymosin Correct immunological deficiencies Thymopoietin Induces differentiation of precursor lymphocytes in thymocytes Dopamine Function- inhibit the release of prolactin (PRL) from the pituitary Prolactin- helps for the preparation of breast for milk production during pregnancy Somatostatin Secreted by the cells in the pancreas and intestines Mixture of 2 peptides Inhibits the release of growth hormones Supports body growth by Binding to receptors on liver cells which stimulates Insulinlike growth factor-1 that promotes long bones to grow thyroid stimulating hormones DiGeorge Syndrome THYMUS A rare congenital defect that causes dysfunction of a number of different tissues Weak immune system and proneness to infections Symptoms: shortness of breath, weakness, failure to gain weight, bluish skin, delayed speech Severe Combined Immunodeficiency THYMUS A genetic disease which results in a weakened immune system Patients often have an atrophied thymus Symptoms: proneness to infections Hypothalamic Disease Disorder of the Hypothalamus Physical injury to the head Symptoms: appetite and sleep problems Hypothalamic Dysfunction Abnormal function of the thalamus located in the brain. Symptoms: delayed puberty, impaired vision, fatigue Interesting Facts -The thymus gland is the main part of your body that makes t cells. In fact, the "t" in "t cells" stands for the word "thymus." -The endocrine system contains over thirty different types of hormones. Concept Check 1. The thymus gland is located… a. In the brain b. Behind the sternum c. Near the intestines 2. DiGeorge Syndrome is… a. Inherent b. A disease of the hypothalamus b. c. A cause for an atrophied thymus 3. What is secreted by cells in the pancreas and intestines? a. Somatostatin c. Dopamine c. Thymosin 4. Describe the function of the hormones of the hypothalamus. Concept Check Answers 1. The thymus gland is located… a. In the brain b. Behind the sternum c. Near the intestines 2. DiGeorge Syndrome is… a. Inherent b. A disease of the hypothalamus b. c. A cause for an atrophied thymus 3. What is secreted by cells in the pancreas and intestines? a. Somatostatin c. Dopamine c. Thymosin 4. Describe the function of the hormones of the hypothalamus. Dopamine inhibits the release of prolactin (PRL) from the pituitary. Somatostatin Inhibits the release of growth hormones and supports body growth by binding to receptors on liver cells which stimulates Insulin-like growth factor-1 that promotes long bones to grow. Bibliography "About the Thymus Gland." LiveStrong. Ed. Franchesca Vermilliion. N.p., n.d. Web. 10 Mar. 2013. <http://www.livestrong.com/article/119569-thymus-gland/>. Applied Anatomy & Physiology. N.p.: n.p., n.d. Print. Cloe, Adam. "Disorders of the Thymus Gland." LiveStong. N.p., 13 Mar. 2011. Web. 10 Mar. 2013. <http://www.livestrong.com/article/185768-disorders-of-the-thymus-gland/>. Hormones of the Hypothalamus. N.p., n.d. Web. 10 Mar. 2013. <http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/H/HormoneTable.html>. Mayo Clinic Staff. "Digeorge Syndrome." Mayo Clinic. N.p., n.d. Web. 10 Mar. 2013. <http://www.mayoclinic.com/health/digeorge-syndrome/DS00998/DSECTION=symptoms>. Organs of the Immune System. N.p., n.d. Web. 10 Mar. 2013. <http://www.ufrgs.br/imunovet/molecular_immunology/organsimmune.html#thymus>. Rehan, Kelly M. "An Overview of the Hypothalamus." Endocrine Web. N.p., n.d. Web. 10 Mar. 2013. <http://www.endocrineweb.com/endocrinology/overview-hypothalamus>. - - -. "An Overview of the Thymus." Endocrine Web. N.p., n.d. Web. 10 Mar. 2013. <http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/H/HormoneTable.html>. "Severe Combined Immunodeficiency." Learn.Genetics. N.p., n.d. Web. 10 Mar. 2013. <http://learn.genetics.utah.edu/content/disorders/whataregd/scid/>.