CRYDER’S QUIZ #1 MAJOR TOPIC ANSWERS: #1. Define and describe homeostasis as it relates to the three part control loop we discussed, including a discussion of negative feedback as it relates to one example covered in class. Observe the following diagram. 1. Receptors -> 2. Control center -> 3. Effector Homeostasis and Control Loop Homeostasis is the body’s ability to use the nervous and endocrine systems to maintain a stable internal environment regardless of external/internal changes. At the center of this lifesaving process is a three part control loop which includes (1) receptors that monitor the body and, when conditions change enough to disrupt the body’s dynamic balance, will send the appropriate sensory impulses into (2) the control center (the CNS). The control center of the body, which includes the brain and spinal cord, then analyzes this input, interprets its message and determines the appropriate motor response necessary to stabilize the body and return it to equilibrium. As the motor impulses round out and complete this loop by targeting and activating (3) effectors (muscles and glands) which will immediately reverse the specific imbalance and reestablish homeostasis. Negative Feedback Homeostasis, which refers to our body’s life-saving ability to maintain its internal balance by utilizing a wide array of negative feedback mechanisms, requires specific and continuous nervous and endocrine system detection, analysis, and effector targeting in order to appropriately respond to potentially life-threatening changes and imbalances and to effectively re-establish stability before the “equilibrium stimulus” is diminished and subsequently turned off. One example of this process occurring in the body is seen as the body maintains its desired internal temperature of 98.6o F. When a human goes from a 700F room to the outdoors where it’s a scorching 1100 F, a negative feedback loop would be initiated in order to maintain homeostatic balance and prevent any wide variation in body temperature from occurring. As we heat up internally; the body’s receptors would recognize the temperature change, send a sensory nerve impulse to the CNS (control centers within the brain and spinal cord) for analysis and interpretation, and then it would determine which specific effector (muscles or glandular secretion) is appropriate and which specific impulse would reverse the imbalance efficiently and quickly enough to completely stabilize the body’s systems and cool us down. In this case, the best effectors are in the form of sweat glands (embedded within the dermal layer of the skin and covering our entire outer surface) which will immediately activate, release sweat onto our external surface, and quickly cool our core back toward 98.60 F. As balance of temperature is reestablished, the same receptor that initiated the loop will no longer detect imbalance and will stop sending the sensory signal that started the negative feedback mechanism to begin with; the stimulus is diminished and shuts off (as quickly as it was initiated). (Courtesy of Ian Dettman) #1. Define and describe the three most important organ systems and explain why you’ve chosen them. The nervous system and the endocrine system both serve as means of maintaining homeostasis, which is vital to life. The first, which is composed of the brain, spinal cord, and peripheral nerves, allows the body to detect changes in the environment and react accordingly. The endocrine system, on the other hand, consists of a system of glands responsible for hormone secretion that prolongs the nervous response to the given change in the environment. They each work together, therefore, to maintain the balance of homeostasis necessary to life. A third essential body system is the ___________ system, which is made up of the ________________. It is essential on a minute-by-minute basis to life because its function includes ________________________________________________________________. #2. Define and describe the structural levels of organization in the body and circle the basic living unit. On the minutest level, the basic building blocks of matter, called atoms, come together to form molecules, which in turn can combine into macromolecules such as DNA. Macromolecules form organelles, many and varied types of which act in tandem to maintain the cell, the most basic living unit. Multiple cells form tissues, and a combination of tissues will work together in an organ to perform a given function that will complement other organs in an organ system. Finally, an organism survives by maintaining balance between the multiple organ systems that make it up. #3. Define and describe homeostasis as it relates to the three part control loop we discussed, including a discussion of negative feedback as it relates to one example covered in class. The body is able to detect changes in the environment that threaten dangerous imbalances, such as high temperature, through sensory receptors. This information is sent to the control center, i.e., the central nervous system, which interprets and analyzes the data, sensing in this scenario a rising body temperature. An appropriate motor response is initiated by the CNS to address the imbalance and the effectors produce corrective action; the sweat glands go off and evaporation cools the body in an attempt to re-establish/maintain the ideal 98.60 F. Negative feedback in the form of constant reevaluation of the situation (e.g., body temperature detection) controls the intensity of the effector response and serves as a shutoff mechanism once equilibrium is reachieved.