Respiration & Gas Exchange SBI 3U In memory of William: d.o.d 4.1.08 The needs of All Organisms • To obtain oxygen for cellular respiration • To get rid of carbon dioxide from cellular respiration http://www.lima.ohio-state.edu/academics/biology/images/amoeba.jpg Single celled organisms • Usually live in water (aquatic) • Are very small • Have large surface area relative to their volume • transport O2 and CO2 by diffusion. http://www.planet-pets.com/amoeba1.jpg What about Multi-cellular organisms? • Still need oxygen • Still need to remove carbon dioxide • Need to develop specialized structures to carry out the process of gas exchange. • Sponges and jellyfish use diffusion to exchange gases from the surrounding water. Flatworms and worms use their outer surfaces as gas exchange surfaces. Insects , worms, and fish use gills; land vertebrates use internal lungs. Gas exchange takes place • At a respiratory surface such as: •Cell membrane •Skin surface •Trachea •Gills •lungs Organisms without respiratory systems need to be. • Small • Flattened • Tubular • Aquatic All respiratory surfaces need to be.. • • • • Large Thin Moist Well supplied with blood Gas Exchange in Fish Gas exchange in Insects Human Respiratory System Terminology • • • • • • • • Lungs Larynx (voice box) Trachea (windpipe) Bronchi (sing. Bronchus) Nose Epiglottis Bronchioles Alveoli (air sacs) Terminology continued • • • • • • • • • Ribs Diaphragm Intercostal Muscles Pleural membranes Thorax (chest) Inhalation Exhalation Ventilation Lung capacity http://www.rsdrx.com/images/RespiratorySystemLRes.gif Nasal cavity Pharynx Larynx (voice-box) Trachea - windpipe Bronchus (pl bronchi) Pleural membrane around lung Bronchiole Alveoli Diaphragm How do gases travel in the blood? • Some CO2 in the blood is carried bound to hemoglobin or dissolved in plasma. Most CO2 is transported as bicarbonate ion, generated from carbonic acid that forms when CO2 reacts with water and ionizes. The Enzyme Carbonic anhydrase speeds this reaction. The process reverses in the lungs, releasing CO2 for expiration. What happens during breathing? • Air enters the nose • Air is warmed, moistened and filtered • Air passes behind the pharynx over the voice box • The epiglottis (a flap of skin) stops the food going down the trachea when swallowing • Air passes down the trachea and branches to the two bronchi. http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookRESPSYS.html A. Inhalation The intercostal B. Exhalation The intercostal muscles contract, lifting the rib cage up and out. At the same time, the diaphragm contracts and pulls downward. As the lungs expand, air moves in. muscles relax, allowing the rib cage to return to its normal position. The diaphragm also moves upward, resuming its domed shape. As the lungs contract, air moves out. • The trachea and bronchi are kept open by rings of cartilage. • The lining of the trachea and bronchi are covered with cilia which continually move dirt and mucus upwards towards the nose and mouth • The bronchi divide like the braches of a tree getting smaller and smaller • The bronchioles finally end in small single celled sacs called alveoli (air sacs) • Gas exchange takes place in the alveoli http://webanatomy.net/histology/respiratory/alveoli.jpg In the Alveoli http://www.dannynicholson.co.uk/learningzone/body/organs/Alveoli.jpg CO2 Capillary cell Plasma O2 Alveoli Red blood cell Moisture Exchange of Gases: Composition of inhaled and exhaled air – Gas % Inhaled Air Exhaled air Oxygen 20% 16% Carbon dioxide 0.04% 4.0% Nitrogen 79% 79% Water Vapour Varies Saturated Regulation of Breathing Movement When a child, in a temper tantrum, holds his or her breath, the medulla oblongata in the brain eventually takes over the control of breathing and the child is forced to breathe. Breathing is an involuntary activity. It is controlled by a negative feedback loop that keeps the oxygen and carbon dioxide concentration in the blood relatively constant Oxygen is vital to all parts of the body, but the brain is especially sensitive to a low level of oxygen. If the brain is deprived of oxygen for more than four minutes, irreversible brain damage occurs. Possibly for this reason, the medulla oblongata controls vital mechanisms like breathing and heart rate. The mechanism of breathing is coordinated by chemoreceptors that detect changes in the pH of the blood. These special receptors are sensitive to the levels of gases in the blood, especially the level of carbon dioxide. Levels of CO2 in the blood regulate breathing in the Medulla Oblongata Problems of the Respiratory System Normal Lungs & Heart Fluid in the Lungs Cancer in the left lung Lung Cancer Cystic Fibrosis