P16081: SYSTEMIC CIRCULATION MODEL
SUBSYSTEM DESIGN REVIEW
John Ray
Fabian Perez
Robert Kelley
Mallory Lennon
Jacob Zaremski
Agenda


Our goals for this review
Updates from Phase II Review
(10 minutes)

CAD Schematic Analysis
Subsystem Analysis
(25 minutes)
Risk Analysis
Bill of Materials (BoM)
Project Plans
(5 minutes)
(5 minutes)
(5 minutes)




Goals
1. Introduce progress in engineering analysis
2. Address budget concerns
3. Demonstrate efforts to design for modification
4. Receive feedback
5. Create action plan
Finalized Objective
Our goal is to deliver a functioning physical model of systemic circulation which, when
used in conjunction with P16080’s heart pump, will be used as a teaching tool, allowing
students to validate mathematical models of the circulatory system from Chapter 5 of
“Quantitative Human Physiology” An Introduction by Joseph Feher. The model will
ultimately enhance students' understanding of the circulatory system by enabling
them to analyze the circulatory system under normal, exercise, and pathological conditions
through the measurement of pressure and flow.
Updated Use Case
ER Metrics of Quality (1 of 3)
ER Metrics of Quality (2 of 3)
ER Metrics of Quality (3 of 3)
ER mapping to F.D. (1 of 2)
ER mapping to F.D. (2 of 2)
Functional Decomposition
Morph Chart (1 of 3)
Morph Chart (2 of 3)
Morph Chart (3 of 3)
Undecided Concepts
Pressure
• PASCO versus Honeywell
• LabVIEW versus DataStudio
Resistance
• External Clamp vs. Valve
Updated System Architecture
CAD
Schematic
Main Components
Barb tube fitting:
cheapest, easiest
connection
Ball pump:
cheapest,
easiest way to
add air pressure
Pressure tap into
tubing
Pressure release value:
easy release valve
Drill and screw
into acrylic
7
9
8
1
Pressure, PA
Flow
P16081 Pump
Arterial
Compliance,
CA
4
5
Venous
Compliance,
CV
Pressure, PV
2
3
Resistance
Pressure,
v PC 6
LabVIEW
Subsystems Agenda
1 & 5 - Pressure
2 & 4 - Compliance
3 - Resistance
6 - Labview
7, 8 & 9 - Consult with P16080
Pressure Sensor Analysis
1. Flow Diagram
2. PASCO Sensors
3. Honeywell Sensors
4. Bill of Materials
5. Test Plan
6. Risks
Energy
Pressure Flow Diagram
Analog Pressure
Signal
Information
Digital Pressure
Signal
Amplifier Board
DAQ
Pressure vs.
Time Graph
LabView
Program
Computer
AC Power
PASCO Sensors
Pros
Already Owned
Differential Pressure
Capabilities
Cons
http://www.pasco.com/file_downloads/product_
manuals/PASPORT-Dual-Pressure-SensorManual-PS-2181.pdf
No integration with LabView
Special Pressure Taps
Needed
User Friendly
Will need more than one computer for real
time system analysis
• LabView for heart, DataStudio for
circulatory pressures
• LabView needed for automatic
resistance control
Maximum Sampling
Rate
1000 Hz
Absolute Pressure
Range
0-1500 mmHg
Differential Pressure
Range
-750-750 mmHg
Resolution
0.075 mmHg at 10 Hz
Repeatability
7.5 mmHg
Tubing (Type)
Polyurethane
Tubing Size
(Diameter)
3.2 mm
Tubing Length
2.4 m
Interface
Data Studio (New one coming
soon?)
Source:
PasPort Instruction Sheet (01209969A)
Honeywell Sensors
Pros
Cons
Integration With
LabView
More Expensive than
PASCO
Accuracy
Will need a Sensor
Board/DAQ
Liquid Friendly
Only one computer program needed for
both heart and circulatory
• DAQ is already provided, but would
need to build the circuit
board/LabView Program
http://www.mouser.com/ProductDet
ail/Honeywell/HSCMRNT005PGAA
5/?qs=%2fha2pyFaduhkciXVz6btF
HLY3u79xkDhknp39AuPvmffYIGgr
Gx0aQ%3d%3d
TruStability Board Mount Pressure Sensors: HSC Series
(HSCMRNT005PGAA5)
Operating Gage Pressure Range
0-258 mmHg
Output Type
Analog
Pressure Type
Gauge
Operating Supply Voltage
5V
Operating Temperature
-40-85 C
Operating Supply Current
20 mA
Accuracy
0.25%
Liquid Media Capable?
Yes
Source:
HSCMRNT005PGAA
5 Datasheet
(Mouser.com)
Honeywell Sensors
Dimensions
http://www.mouser.com/ProductDetail/Honeywell/HSCMRNT005PGAA5/?qs=%2fha2pyF
uPvmffYIGgrGx0aQ%3d%3d
Pressure BOM
Component Componen
ID
t
Supplier
Supplier ID
Quanitity/Dimensions
Price/Unit
P1
Honeywell Mouser
HSCMRNT005PGAA5
Board
Electronic
Mount
Pressure
Sensor
2
P2
PASCO
Sensor
PASCO
PS-2181
2 Free
P3
Pressure
Taps
PASCO
ME-2224
6
Total
Cost
Notes
$45.78 $91.56 May only
need 1
(48.85)
-
Already
Owned
$16.00 $96.00 Comes as
a set of 6
Might be able to
borrow for free (Rep
mentioned it)
Pressure Risks
5
Technical
Not being able to generate required values
6
Technical
Seal on the pressure tap leaks
7
Technical
Not being able to calibrate within time constraints
9
Resource
System components will be expensive
11
Safety
Electricity and water combination can cause
dangerous conditions
Owner: Jack
PRESSURE TEST PLAN
1. Prove Sensor Functionality
a. Flow through a pipe with decreased diameter in the center
b. Pressure taps at two points
c. Measure the pressure drop
2. Calibration of the Sensors
a. Obtain a full tank of known pressure
b. Measure the pressure and correct accordingly
Subsystem - Compliance Tank
1. Flow Diagram
a. Energy, Material, and Information I/O
b. Interfaces
2. Cylinder or rectangular prism?
a. Pros and cons
b. Feasibility
3. Bill of Materials (Draft)
4. Subsystem Risks
5. Preliminary Ideas for Testing Plans
Forced Air
Air
Height
Pressure
Compliance
Pressure
Flow
Flow
Energy
LabVIEW
Pressure vs. Time
Pressure Transducer
AC Power
Information
Material
Cylindrical Tanks
Pros
Fewer pieces
Less interfaces to seal
Cons
Price limits diameter
Interfacing with tubing and pressure taps
Rectangular Tanks
Pros
Flat surfaces easier to machine and
interface
Cons
More pieces that need to be machined
and sealed
Compliance (mL/mmHg)
Cylindrical Arterial Compliance Tank
Polycarbonate 5.75ID
[in]
Acrylic 5ID [in]
5
4.5
4
3.5
3
2.5
2
1.5
1
0.5
0
0
2
4
6
Height (inches)
8
10
12
Cylindrical Venous Compliance Tank
35
Acrylic 9.75ID [in]
Compliance (mL/mmHg)
30
Polycarbonate 5.75ID
[in]
25
20
15
10
5
0
0
5
10
15
Height (inches)
20
25
Rectangular Arterial Compliance Tank
Compliance (mL/mmHg)
9
8
4x4x12 [in]
7
4x8x16 [in] (Donovan)
6
5
4
3
2
1
0
0
2
4
6
8
10
Height (Inches)
12
14
16
Rectangular Venous Compliance Tank
40
Compliance (mL/mmHg)
35
12x12x16 [in]
30
12x8x16 [in] (Donovan)
25
20
15
10
5
0
0
2
4
6
8
Height (inches)
10
12
14
16
Technical Risks - Compliance Tank
Resource & Safety Risks - Compliance
Tank
Compliance BOM - Cylindrical
Compliance BOM - Rectangular
• 6-sided tank would be around $200
Compliance - Preliminary Testing Plans
1. Air tight seal
a. pressurize, use soap, and look for bubbles
2. Generate chart to allow students to know which height
corresponds to a desired condition - scale on box
3. Excel spreadsheet for liquid height and corresponding
compliance values
Resistance Agenda
1. Flow Diagram
2. Valve and Resistance Analysis
3. Bill of Material and Alternative Bill of Materials
4. Risks
5. Test Plans
Resistance Flow
Valve and Resistance Analysis
Resistance can be modeled after Ohm’s Law in that: R=ΔP/F where ΔP is
the height difference and F is the mean flow rate.
[http://circ.ahajournals.org/content/89/2/893.full.pdf]
Valve and Resistance Continued
For Valves resistance and friction can be modeled as:
hf=(Kv^2)/2g
Where K is the resistance coefficient, f is the Darcy friction
factor, V is the velocity and hf is the Frictional Loss or
Head Loss.
Considering using a Gate valve for purposes of the
design.
● Resistance will have to be tested manually
○ Test each resistor position and correlate them to the
pressure output seen
■ Create a graph of resistor position vs pressure output
Valve Considerations
Other potentials: Linear Actuator and Globe Valve
Resistance BOM
Current BOM
Subsystem Component ID
Valve
Component
Bronze Gate ValveClass 125, 3/4" NPT
Female, Non-rising
Stem
V1
Supplier
Supplier
ID
Quanitity /
Dimensions Price/Unit Total Cost
McMaster
Carr
4619K14
1
$27.96
Notes
May be alternated for linear
$27.96 actuator
Alternative BOM
Subsystem
Linear
Actuator
Globe Valve
Component ID
Component
Supplier
Supplier
ID
LA1
25mm Diamter Actuator Anaheim TSFCA25
Exteded strew with
Automatio -150-21motor
n
023-LW4
GV
Low-Pressure Bronze
Globe Valve, 3/4" NPT
Female, EPDM Disc
McMaster
Carr
4695K65
Quanitity /
Dimensions Price/Unit Total Cost
11
1
Notes
$39.00
Can only apply 10 Newtons
$39.00 of Force.
$37.44
Meant for low pressure
flows, overall length of 2
$37.44 5/16”
Resistance Risks
Resistance - Preliminary Testing Plans
1. Calibration
a. Make sure when impedance is 0 R=ΔP/F is obeyed.
b. Make sure when impedance is at max there is no flow through the
system after this point.
2. Calculate theoretical head loss through circuit and
perform head loss experiment on the pipe and valve to
confirm compliance to the theoretical model (initial set up
for MSD)
LabVIEW
LabVIEW Considerations
F. M. Donovan (1975) Design of a Hydraulic Analog of the Circulatory System
for Evaluating Artificial Hearts, Biomaterials, Medical Devices, and Artificial
Organs, 3:4, 439-449
Venous
• Waveform consistency
• Same parameters give
same waveforms each time
• Interfacing with pressure
sensors
• One program for both
teams
Arterial
Preliminary Life Span Calculation
Considerations:
What will likely fail first?
Is that part expensive?
Is that part easy to replace?
New risks
Mitigated Risks
Risk Chart
Draft System Bill of Materials (1 of 2)
Draft System Bill of Materials (2 of 2)
Project Plan - what we achieved
Project Plan - deliverables for next phase
End of MSD I Deliverables
1.
2.
3.
4.
5.
6.
7.
“Working” theoretical model
Finalized, completed and accurately priced Bill of Materials
CAD drawing 100% done
Test plan for design 90% complete
Theoretical risk list complete with ideas as to how to minimize
potential effects
Understanding of deliverables for MSD II
Short list of contests this design could enter
Ways to Improve Efficiency
1. More organized direction for research of parts and
materials
2. Better collaboration with P16080
3. More organized group meetings
Goals for Phase IV
1. Choose the most efficient pressure sensor
2. Decide on dimensions for compliance tanks
3. Decide on internal versus external resistances
4. Interactions with P16080
• LabVIEW
• Flow meter
• Interfacing
ASEE 123rd Annual Conference & Exposition
• Abstract submitted on October 20th, 2015
• Abstract decision deadline: November 9, 2015