11.3 KARYOTYPE ACTIVITY
NAME___________________________HR_____
-In this activity, you will use a computer model to look at chromosomes and prepare a karyotype.
-You will diagnose patients for abnormalities and learn the correct notation for characterizing karyotypes.
SITE 1- http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html
READ INTRO
1. What causes a dark band on the chromosome? _______________
2. What is a centromere? ________________
-when you have completed the background reading:
-CLICK PT. HISTORY
COMPLETE KARYOTYPE for patient A, B, and C.
INTERPRET each karyotype
Patient A (Click on the link to "Complete Patient A's Karyotype" )
1. What is patient A's history (summarize) ______________________________________________
2. How many total chromosomes are in your karyotype - count them _________
3. What sex chromosomes does your patient have ________
4. Which chromosome set has an extra + _______
5. Write out the correct notation for this karyotype. ________
6. What is the diagnosis? ___________________________________________________________
Patient B - click on the link to go to Patient B and repeat the above process.
1. What is Patient B's history (summarize) _______________________________________________
2. How many total chromosomes are in your karyotype - count them _________
3. What sex chromosomes does your patient have ________
4. Which chromosome set has an extra + _______
5. Write out the correct notation for this karyotype. ________
6. What is the diagnosis? ____________________________________________________________
Patient C - click on the link to go to Patient C and repeat the above process.
1. What is patient C's history (summarize)? _________________________________________
2. How many total chromosomes are in your karyotype - count them _________
3. What sex chromosomes does your patient have ________
4. Which chromosome set has an extra + _______
5. Write out the correct notation for this karyotype. ________
6. What is the diagnosis? ____________________________________________________________
SITE 2- http://www.biology.arizona.edu/human_bio/current/new_karyotyping/new_karyotyping.html
READ: about new methods in karyotyping
SUMMARY: provide a 17 word sentence summary of the reading
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SITE 3- Genetic Science Learning Center
http://learn.genetics.utah.edu/content/chromosomes/
-CLICK KARYOTYPES / How do Scientist Read Chromosomes
READ: each section
SUMMARY: provide a summary / picture for each topic
HOW DO SCIENTIST READ CHROMOSOMES?
WHAT ARE CENTROMERES FOR?
CENTROMERE POSITION
SITE 3- Genetic Science Learning Center
http://learn.genetics.utah.edu/content/chromosomes/
-CLICK KARYOTYPES / Using Karyotypes to Predict Genetic Disorders
READ: each section
ANSWER: provided questions
1. What is trisomy?
____________________________________
2. What is monosomy?
____________________________________
3. What is a terminal deletion? ____________________________________
SITE 3- Genetic Science Learning Center
http://learn.genetics.utah.edu/content/chromosomes/
-CLICK SEARCH BOX [type each into the search box - top right corner]
DESCRIBE the chromosome abnormality and the symptoms.
1.Cri Du Chat
-______________________________________________________________
-______________________________________________________________
2.Williams Syndrome
-______________________________________________________________
-______________________________________________________________
SITE 3- Genetic Science Learning Center
http://learn.genetics.utah.edu/content/chromosomes/
-CLICK CHROMOSOMES / Are telomeres the key to aging and cancer
READ: each section
ANSWER: provided questions
1.What are telomeres?
2.Why do chromosomes have telomeres?
3.Why do telomeres get shorter each time a cell divides?
4.How can telomeres be used to detect cancer?
5.How big is the role of telomeres in aging?