INTEGRATION OF NUTRITION INTO HIV AND OTHER INFECTIOUS DISEASES :THE NACS APPROACH Serigne M. DIENE, PhD, Senior Nutrition and HIV Advisor AIDS 2012 Communications-Hosted Satellite Session July, 22, 2012 Food and Nutrition Technical Assistance III Project (FANTA) FHI 360 1825 Connecticut Ave., NW Washington, DC 20009 Tel: 202-884-8000 Fax: 202-884-8432 Email: fantamail@fhi360.org Website: www.fantaproject.org III Presentation Outline • Evidence Supporting NACS • NACS’s overview • Elements of the NACS approach III Emerging evidence • Evidence is emerging on the impact of various nutrition interventions on the health and wellbeing of PLHIV. • Opportunities for randomized controlled trials were limited in the past but are expanding with the increased adoption of NACS. III EVIDENCE SUPPORTING NACS III Supplementary Feeding and Nutritional Status Outcome Findings Other Comments Kenya - Food Supplementation v Control (n=1058)1 ART Group 1.9kg v 1.0kg at 1/12 4.6kg v 3.4kg at 3/12 Pre-ART Group Food Supp significant in change in BMI at 3/12 & 6/12 * CD4 ↑ int. at 3/12 and CD4 ↓ control at 3/12. Not signif. at 6 or 12/12 * Food predictor of attendance at 6/12 in both Malawi - Fortified Spread (FS) v Corn Soy Blend (CSB) (n=491) 2 Greater anthropometric ↑ FS group v CSB group at 14/52 BMI change (2.2 v 1.7), weight change (5.6kg v 4.3kg), FFM (2.9kg v 2.2kg), and MUAC (2.2cm v 1.6cm) * BMI at enrollment 16.5. * Mortality rate 27% for FS and 26% for CSB * Spread 3x more expensive * No differences in CD4 count, VL, QoL, or adherence Zambia – CSB/Oil/Beans v Control (n=636)3 No differences were not found for weight gain *Food supplementation assoc. with better adherence * No difference in CD4 change India – Fortified Blended Food (Indiamix) v Control (n=636)4 Food supplementation did not result in increased weight compared with nutrition counseling and standard care * ↑ in weight, BMI, MUAC, FFM, and BCM in both groups All results reported in findings are significant unless indicated III 1. 2. 3. 4. KEMRI, FANTA Project - Report June 2011 Ndekha MJ et al.. BMJ. 2009 May 22;338:b1867 Cantrell RA,. J Acquir Immune Defic Syndr. 2008 Swaminathan S,et al. Clin Infect Dis. 2010 Jul 1; Micronutrient Supplementation and Disease Progression Outcome Findings Other Comments Tanzania – MMVM v MMVM/Vit A v Vit A v Placebo (n=1078)1 •24.7% MMVM progressed to WHO stage 4 or died •31.1% placebo progressed to WHO stage 4 or died •MMVM group had reduced risk of AIDS related death •MMVM and MMVM/Vit A group had fewer people progress HIV stage 3 or higher. •The MMVM and MMVM/Vit A had slight increases in CD4+ •MMVM group had slight reduction in viral loads. USA – MMVM v Placebo (n=40)2 • MMVM group – CD4 ↑ 65 cells/mL (↑ 24%) at 12/52 •Placebo group - CD4 ↓ 6 cells/mL (↓ 0%) at 12/52 •Study period was over 6 years •>1000 pregnant women enrolled •Vit A group had similar results to placebo •MVM group also had reduced incidence of complications •No change in any other biochemical parameters e.g. blood lipids and glucose •42% improvement in neuropathy symptoms in MMVM group, •33% improvement in neuropathy symptoms in placebo group – result not statistically significant but clinically significant. All results reported in findings are significant unless indicated III 1. 2. Fawzi WW, et al. A N Engl J Med. 2004 Jul Kaiser, JD.. J Acquir Immune Defic Syndr. 2006 Aug 15 OVERVIEW OF NACS III What is NACS? • Nutrition assessment, counseling, and support (NACS) is an approach that aims to improve the nutritional status of individuals and populations by integrating prevention and treatment of malnutrition into policies, programs, and health service delivery infrastructure. • The NACS approach strengthen the capacity of facility- and community-based health care providers to deliver nutritionspecific services while linking clients to nutrition-sensitive interventions provided by the health, agriculture, food security, social protection, education, and rural development sectors. III III N A C S Nutrition Assessment, Counseling, & Support N A C S NACS Establishing a Nutrition Standard of Care III GOAL: Improved health and quality of life • • • • Nutrition care & support OBJECTIVES: Improve nutritional status Improve infant survival Reduce food insecurity Strengthen health systems HIV-Free Survival Economic strengthening, livelihoods & food security Health system strengthening NACS: A platform for integrating nutrition into the continuum of care III NACS: A Life Cycle Approach NACS III C&T ART & ARV Prophylaxis Tx of Malnutrition Maternal Nutrition & IYCF Counseling Photos: Wendy Hammond Pregnancy Birth III Infancy Childhood Adolescence Photo: Wendy Hammond Adulthood ART & ARV Prophylaxis Peri-/Postnatal Care Maternal Nutrition & IYCF Counseling Pregnancy Birth III Infancy Photo: Wendy Hammond Childhood Adolescence Adulthood Postnatal Care Deworming Micronutrients IYCF/GMP CMAM Tracking/Follow-Up of Mother-Infant Pairs Photos: Save the Children Federation Pregnancy Birth III Infancy Childhood Adolescence Adulthood Pediatric Care Nutrition Surveillance/GMP & Referral Micronutrients CMAM Photo of Plumpy’nut® from Valid International; all others: Save the Children Federation Pregnancy Birth III Infancy Childhood Adolescence Adulthood Nutrition Surveillance, Referral, Assessment & Counseling Deworming Micronutrients CMAM Nutrition Surveillance, Referral, Assessment & Counseling Micronutrients Tx of malnutrition Photo: LINKAGES Project Pregnancy Birth III Infancy Childhood Adolescence Adulthood Why NACS? • Evolved in HIV, specifically from model of Food By Prescription • Links vulnerable to clinical services -- reciprocal impact between health & nutrition • Continuum of Care from rehabilitation to chronic nutrition management • Link patients to support groups & community services • Referrals for economic strengthening, livelihood & food security (ES/L/FS) support • Contributed to overall health system strengthening III NACS Hinges on Nutrition Assessment 1. Routine Comprehensive Assessment • Anthropometry • Biochemical • Clinical • Dietary • Household Food security 2. Analyze/interpret data using evidence-based standards 3. Identify nutrition problems 4. Determine causes/contributing risk factors 5. Cluster signs/symptoms and defining characteristics 6. Determine an appropriate Nutrition Care Plan III Nutrition Counseling 1. Understanding of client preferences, constraints & options 2. Nutrition Care Plans 3. Optimal diet 4. Dietary management of symptoms 5. Dietary management of drug side-effects 6. Adherence to medications & clinical visits 7. Chronic disease management 8. Exercise 9. Water, sanitation, and hygiene (WASH) 10. Referral to community services, including household ES/L/FS support III Nutrition Support Treatment of Malnutrition Prevention of Malnutrition Economic Strengthening, Livelihood & Food Security Support Water, Sanitation, & Hygiene (WASH) • Corrective Medical Care & Treatment • Food by Prescription • Provision of MN Supplements • Routine Medical Care & Tx • Provision of MN Supplements • Provision of Complementary Foods/Dietary Supplements • Savings • Microcredit • Incomegenerating activities • Household food production • Food assistance • Distribution of POU water treatment products or vouchers • Latrine construction III NUTRITION SUPPORT NUTRITION COUNSELING Exercise IYCF/GMP Maternal Nutrition Nutrition Care Plan Clinic Food by Prompt Prescription: treatment of Therapeutic, infections Supplementary & Complementary Adherence to medications Foods NUTRITION ASSESSMENT Anthropometry Clinical Dietary Biochemical Support Groups Household food rations Community Community Health Workers Food security Dietary management of symptoms, drug side-effects and drugfood interactions Economic Strengthening, Livelihoods & Food Security WASH Point-of-use water treatment Micronutrient supplements 22 Enabling Environment SUN/ 1000 Days Feed the Future Policies, Strategies & Guidelines Training Supply Chain Management Funding/Financing PEPFAR Research/M&E Community Demand Mapping/ Strengthening Services Referral Links & Tracking NACS Global Health Initiative Human Resources III Quality Improvement Title II COMMUNITY Service Gaps Pre-NACS…. CLINIC Limited linkages and referrals 24 The NACS Approach…. COMMUNITY CLINIC 25 Along the continuum of care, in a way that is client centered that includes assessment, counseling, and support with referrals and effective coordination for optimal quality and impact III Phased Implementation of NACS in HIV Early Planning & Implementation South Africa, Mozambique, Vietnam Program Expansion Côte d’Ivoire, Ghana, Ethiopia, Uganda, Tanzania, Namibia, Zambia, Haiti Implemented at National Scale Malawi and Kenya III Elements of the NACS Approach III Integrating Nutrition into National HIV Responses (1) • National Policy and Coordination – National nutrition and HIV guidelines – National nutrition and HIV strategy – Nutrition incorporated into HIV policies and vice versa – Technical coordinating group – Nutrition focal point in National AIDS Control Program III Integrating Nutrition into National HIV Responses (2) • Capacity Strengthening – In-service and pre-service training of health care providers (linking the two ?) – Job aids – SBCC materials – Anthropometric equipment – Mentoring and supervision – QA/QI – M&E III Integrating Nutrition into National HIV Responses (3) • Service delivery – Nutrition assessment – Nutrition education and counseling – Specialized food products – Micronutrient supplementation – Water , sanitation, and hygiene (WASH) – Food security support III THANK YOU III