1 2 What is Biology? •Bios- =life •-logy = study of •Study of Life 3 Major Branches of Biology: 1. Botany • Plant Biology 2. Zoology • Study of animals Cytology: Genetics: Ecology: What makes something alive? (What do all living things have in common?) Think/Pair/Share Characteristics of Living Things 4 Made up of Cells -Multi- or uni2. Can reproduce Metabolism 3. Grow and Develop 4. Obtain & use material Homeostasis for energy 5. Maintain a stable internal environment 1. Textbook pgs 1519 Characteristics of Living Things 5 DNA Evolution 6. Based on a universal genetic code 7. Change over time 8. Response to their Environment 6 Cells 7 Reproduction Asexual Reproduction Sexual Reproduction Asexual reproduction is the formation of new individuals from the cell(s) of a single parent. It is very common in plants; less so in animals. Sexual reproduction is the formation of new individuals from the fusion of gametes. Two parents 8 Metabolism • Sum of all of the chemical reactions in the body. • Breakdown and build up. 9 Universal Genetic Material • DNA • Information passed from parent to offspring 10 Characteristics of Living Things 1. Made Up of Cells 2. Reproduce 3. Are Based on a Genetic Code 4. Growth and Development 5. Need for Materials and Energy 6. Response to the Environment 7. Maintaining Internal Balance 8. Evolution (change over time) 11 12 Organic Chemistry 13 • Study of Compounds that All living things contain Carbon. contain the element Carbon. • Why is carbon so interesting? 1-Carbon has 4 valence electrons. 2-Carbon has the ability to form more compounds than any other element. Organic Compounds contain Carb CARBON SKELETONS 14 CREATES DIVERSITY Organic Compounds contain Carb What are we composed of? -We have structure- Nucleus Cell DNA Ribosomes Endomembrane make up Organelles Proteins Macromolecules make up Compounds make up Atoms Lipids Carbohydrates Nucleic acid Carbon compounds Functional groups Elements Covalent bonds Organic Compounds contain Carbon. 15 16 Macromolecules of Life 4 basic Molecules 1.Carbohydrates 2.Lipids 3.Proteins 4.Nucleic Acids arbohydrates=energy 17 Carbohydrates = Sugars arbohydrates=energy 18 Carbohydrates arbohydrates=energy 2 main functions 1) Provide energy to living cells. – Main Source of energy. 2) Structural Components -cell walls • Elements: CHO (1:2:1 ratio) – The name carbohydrate means "watered carbon" or carbon with attached water molecules. 19 arbohydrates=energy Vocabulary Check • Monomer- Single unit • Polymer- many units One Monomer + One Monomer = Polymer 20 Many molecules are made of up one or more smaller units. 21 arbohydrates=energy JOKE BREAK This is PAUL LEMUR. He's a lemur named Paul. arbohydrates=energy Simple sugars Monosaccharides C6H12O6 one sugar unit •Glucose- plants make during photosynthesis •Galactose-milk RNA Apple Juice 22 arbohydrates=energy Disacchrides •two sugars What molecule will this make? 23 Sucrose • Table Sugar • Plant transport Disacchrides 24 Carbohydrates=energ Polysaccharides •“Many sugars” 25 • Glycogen (pictured) • Glycogen functions as a fuel store in animals. -Large amounts are stored in liver and muscle and maintain circulating blood glucose levels between meals. Carbohydrates=energ Polysaccharides •“Many sugars” 26 Carbohydrates=energ •Starchplants store sugars in this form. arbohydrates=energy 27 Polysaccharide Viewed under a microscope, the starch grains in these plants cells are visible as small dots. Energy 28 • Carbohydrates store energy in their chemical bonds. • Your body breaks down the sugars to get energy. Polysaccharide Animation Carbohydrates=energ Plant Cell Walls Structure •Cellulose arbohydrates=Structure Polysaccharide 29 30 Carbohydrates=energy & struct storage storage structure Carbohydrates Review 31 Used for: • Carbohydrates are the major source of energy for most living things and include sugars, like glucose and sucrose, and starches. – Starches are long chains of sugars. • Plants and some animals use carbohydrates for structural purposes. – An example of this is cellulose, which is found in plant cell walls, and chitin found in the exoskeleton of arthropods. Made of: • Carbohydrates are made up of carbon, hydrogen, oxygen, with a 2:1 ratio of hydrogen to oxygen. and Carbohydrate Review Clip (Std Dev Lipids=Store energy & membranes Lipids Overview Long-term Energy Storage Elements 32 : C, H, O More carbon-hydrogen (C-H) bonds than carbohydrates. Commonly called fats, oils, and waxes. They are insoluble in water due to the nonpolarity of the molecules. Make good cell membranes. Cells use lipids for: Long-term energy storage. Cushions & Insulation. Protective coatings & Waterproofing Cell membranes (Phospholipids). Examples: Fats, oils, waxes Cutin in plants. It helps plants retain water (waterproofing). Lipids=Store energy & 33 Structure of Lipids 34 ENERGY stored in the C-H bonds! •Glycerol backbone w/ 3 fatty acid chains Lipids=Cushions & Protects Glycerol fatty acid chains Phospholipids & Membrane Structure • Lipids “don’t like” water. Lipids=Store energy & 35 36 Saturated Fat -No double bonds, so they lay flat. "the enemy" -Solid at room Temperature Lipids=Cushions & Protects Unsaturated Fat -Double bonds, so they DO NOT lay flat. "the good guys"! -Liquid at room Temperature Lipids Review Used for: • Lipids provide insulation, store energy, cushion internal organs, and are found in biological membranes. • The waterproof, waxy surface of some leaves contains lipids. – Examples of lipids include fats and oils. Made of: • Lipids are made up of oxygen. carbon, hydrogen, & • The structural building block of a lipid is the fatty acid combined with glycerol (a type of alcohol). 37 38 Nucleic Acid=Store & Transmit Genetic 39 NUCLEIC ACIDS Function: C, H, O, N, P Stores and transmits genetic information •Two TYPES of nucleic acids – 1. DNA (deoxyribonucleic acid) – double strand of genetic information 2. RNA (ribonucleic acid) – single strand copy of DNA used to build Nucleic proteins Acid=Store & Transmit Genetic • Nucleotides Polymers of nucleotides (monomers) have 3 parts: 1. A phosphate group 2. A sugar 3. A base. 40 Stores and transmits genetic informatio Nucleic Acids Review Used for: • Nucleic acids contain all the information that an organism needs to live. • Nucleic acids direct the construction of proteins. The genetic information an organism receives from its parents is in the form of nucleic acids. Made of: • The two types of nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are composed of chains of nucleotides. • Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. 41 Proteins Functions • Transport molecules 42 C, H, O, N, S • Hemoglobin transports oxygen • Storage molecules • Iron stored in the liver in a protein complex • Mechanical support • Skin, bones, hair, & nails contain collagen • Hormones • Enzymes • Speed up chemical reactions • Helps control metabolism. • Immune System • Antibodies in the immune system Proteins-Structure • Elements: CHONS • Made of small units called Amino Acids Amino Acids •Amino Acids are the building blocks of proteins. 43 44 Bonds that holds Amino Acids together is called a Peptide Bond. JOKE BREAK….. 45 • Protein can be large complex molecules. Function of a protein depends on the Amino Acid sequence, shape and its ability to recognize and bind to some other molecule. Denaturing Proteins 46 • pH, salt, temp, etc. are altered, protein may unravel and lose its conformation and no longer works. When the amino acid sequesnce is wrong: Sickle Cell Anemia: •Can have fatal consequences. •Ex: Inherited disease, sickle cell anemia, results from a single incorrect amino acid at the 6th position of a protein chain out of 146. 47 Proteins Review Used for: • Proteins include: enzymes, some hormones, antibodies, and various structural parts of organisms are proteins. – These protein molecules differ in the number, kinds, and sequence of amino acids they contain. Made of: • Proteins are made up of chains of amino acids. The 20 amino acids can be combined to form a great variety of protein molecules in living things. 48 49 Enzymes are proteins • Enzymes speed up chemical Enzymes are reaction. biological • These reaction catalysts would take place anyway… -A catalyst is a enzymes just substance that speeds up a speed them up! chemical reaction, but is not Examples of an Enzyme Examples of an Enzyme 50 Without an enzyme! With an enzyme! How do ENZYMES work? 1. The enzyme attaches to one or more of the reactants in a reaction. 2. The reactants that bind to the enzyme are known as the substrates. 3. The part of the enzyme where the substrate attaches to the enzyme is called the active site. 4. The shape of the active site only fits the shape of the substrate, somewhat like a lock fits a key. In this way only the correct substrate binds to the enzyme. 51 52 Active Site Animation 53 Reactants/ Substrates Enzyme Enzymes can only bind to certain substrates this is known as the Lock-and-Key Mechanism. When the reaction is over the Enzyme is left as it was. Animation •Once the enzyme and substrate are together, the enzyme holds the substrate so the reaction can occur. •Once the reaction is over, the enzyme unlocks the product and the enzyme can start a new reaction with an identical substrate. •Enzymes are not permanently changed or used up in reactions Animation 54 Effect of Enzymes Enzymes work by LOWERING the amount of energy required for the reaction to proceed. Reaction pathway without enzyme 55 Activation energy without enzyme Reactants Reaction pathway with enzyme Activation energy with enzyme Products Go to Section: How do you speed up enzymes? 1. Add more of the enzyme. • Warm up the enzyme! Don’t warm it too much or it may denature and stop working. 56 57 A change in the pH of the enzyme can cause a change in the shape of the active site, therefore changing the activity of the enzyme. Animation 53 Each Chemical reaction in your body is helped along by a different enzyme. 54 Enzymes have 4 special features in common 1. They do not make processes happen that would not take place on their own. They just make the processes take place faster! 2. Enzymes are not permanently altered or used up in reactions. 3. The same enzyme works for the forward and reverse directions of a reaction. 4 Each enzyme is highly selective about its substrate. Enzyme pH and Conc lab animation From the EOCT study guide: EOCT Practice Question #1: Which of these molecules are used to store energy in living things? A) carbohydrates and lipids B) carbohydrates and proteins C) lipids and proteins D) lipids and nucleic acids EOCT Practice Question #2: Hereditary information is determined by molecules of… A) carbohydrates B) lipids C) nucleotides SMARTBOARD Review….. Now it’s your turn!