Interventions for Clients with Renal Disorders Pyelonephritis Bacterial infection in the kidney (upper urinary tract) Key features include: Fever, chills, tachycardia, and tachypnea Flank, back, or loin pain Abdominal discomfort Turning, nausea and vomiting, urgency, frequency, nocturia General malaise or fatigue Key Features of Chronic Pyelonephritis Hypertension Inability to conserve sodium Decreased concentrating ability Tendency to develop hyperkalemia and acidosis Acute Pain Interventions Pain management interventions Lithotripsy Percutaneous ultrasonic pyelolithotomy Diet therapy Drug therapy Antibiotics Urinary antiseptics Surgical Management Preoperative care Antibiotics Client education Operative procedure: pyelolithotomy, nephrectomy, ureteral diversion, ureter reimplantaton Postoperative care for urologic surgery Potential for Renal Failure Interventions include: Use of specific antibiotics Compliance with therapies and regular follow-up Blood pressure control Fluid therapy Diet therapy Other interventions Potential for Renal Failure Interventions include: Use of specific antibiotics Compliance with therapies and regular follow-up Blood pressure control Fluid therapy Diet therapy Other interventions Renal Abscess A collection of fluid and cells caused by an inflammatory response to bacteria Manifestations: fever, flank pain, general malaise Drainage by surgical incision or needle aspiration Broad-spectrum antibiotics Renal Tuberculosis Diagnosis Antitubercular therapy with rifampin, isoniazid, and pyrazinamide Complications renal failure, kidney stones, obstruction, and bacterial superinfection of the urinary tract Surgical excision possible Acute Glomerulonephritis Assessment Management of infection Prevention of complications Diuretics Sodium, water, potassium, and protein restrictions Dialysis, plasmapheresis Client education Chronic Glomerulonephritis Develops over a period of 20 to 30 years or longer Assessment Interventions include: Slowing the progression of the disease and preventing complications Diet changes (Continued) Chronic Glomerulonephritis (Continued) Fluid intake Drug therapy Dialysis, transplantation Nephrotic Syndrome Condition of increased glomerular permeability that allows larger molecules to pass through the membrane into the urine and be removed from the blood Severe loss of protein into the urine (Continued) Nephrotic Syndrome (Continued Treatment involves: Immunosuppressive agents Angiotensin-converting enzyme inhibitors Heparin Diet changes Mild diuretics Nephrosclerosis Thickening in the nephron blood vessels, resulting in narrowing of the vessel lumen Occurs with all types of hypertension, atherosclerois, and diabetes mellitus Collaborative management: control high blood pressure and preserve renal function Renovascular Disease Profoundly reduces blood flow to the kidney tissue Causes ischemia and atrophy of renal tissue Diagnosis Interventions: drugs to control high blood pressure and procedures to restore the renal blood supply Diabetic Nephropathy Diabetic nephrophathy is a microvascular complication of either type 1 or type 2 diabetes. First manifestation is persistent albuminuria. Avoid nephrotoxic agents and dehydration. Assess need for insulin. Cysts and Benign Tumors Thorough evaluation for cancer is needed. Cyst can fill with fluid and cause local tissue damage as it enlarges. Many cysts cause no symptoms. Cysts are a structural birth defect that occur in fetal life. Simple renal cysts are drained by percutaneous aspiration. Renal Cell Carcinoma Paraneoplastic syndromes include anemia, erythrocytosis, hypercalcemia, liver dysfunction, hormonal effects, increased sedimentation rate, and hypertension. (Continued) Renal Cell Carcinoma (Continued) Nonsurgical management includes: Radiofrequency ablation, although effect is not known Chemotherapy: limited effect Biological response modifiers and tumor necrosis factor: lengthen survival time Surgical Management Preoperative care Operative procedure Postoperative care: monitoring, pain management, and prevention of complications Renal Trauma Minor injuries such as contusions, small lacerations Major injuries such as lacerations to the cortex, medulla, or branches of the renal artery Collaborative management Nonsurgical management: drug therapy and fluid therapy Surgical management: nephrectomy or partial nephrectomy Polycystic Kidney Disease Inherited disorder in which fluid-filled cysts develop in the nephrons Key features include: Abdominal or flank pain Hypertension Nocturia Increased abdominal girth Polycystic Kidney Disease (Continued) Constipation Bloody or cloudy urine Kidney stones Interventions Pain management Bowel management Medication management Energy management Fluid monitoring Urinary retention care Infection protection Interventions/Complicatio ns Acute and chronic pain Constipation Hypertension and renal failure Nursing interventions to promote selfmanagement and understanding Fluid therapy Drug therapy Measure and record blood pressure Diet therapy Hydronephrosis, Hydroureter, and Urethral Stricture Provide privacy for elimination. Conduct Credé maneuver as necessary. Apply double-voiding technique. Apply urinary catheter as appropriate. Monitor degree of bladder distention. (Continued Hydronephrosis, Hydroureter, and Urethral Stricture (Continued) Catheterize for residual. Intermittently catheterize as appropriate. Follow infection protection measures. Nephrostomy Client preparation Procedure Follow-up care including: Assess for amount of drainage. type of urinary damage expected. manifestations of infection. Monitor nephrostomy site for leaking urine. Interventions for Clients with Acute and Chronic Renal Failure Acute Renal Failure Pathophysiology Types of acute renal failure include: Prerenal Intrarenal Postrenal Phases of Acute Renal Failure Phases of rapid decrease in renal function lead to the collection of metabolic wastes in the body. Phases include: Onset Diuretic Oliguric Recovery Acute syndrome may be reversible with prompt intervention. Assessment History Clinical manifestations Laboratory assessment Radiographic assessment Other diagnostic assessments such as renal biopsy Drug Therapy Cardioglycides Vitamins and minerals Biologic response modifiers Phosphate binders Stool softeners and laxatives Monitor fluids Diuretics Calcium channel blockers Treatment Diet therapy Dialysis therapies Hemodialysis Peritoneal dialysis Continuous Renal Replacement Therapy Standard treatment Dialysate solution Vascular access Continuous arteriovenous hemofiltration Continuous venovenous hemofiltration Posthospital Care If renal failure is resolving, follow-up care may be required. There may be permanent renal damage and the need for chronic dialysis or even transplantation. Temporary dialysis is appropriate for some clients. Chronic Renal Failure Progressive, irreversible kidney injury; kidney function does not recover Azotemia Uremia Uremic syndrome Stages of Chronic Renal Failure Diminished renal reserve Renal insufficiency End-stage renal disease Stages of Chronic Renal Failure Changes • Kidney • Metabolic – Urea and creatinine • Electrolytes – Sodium – Potassium • Acid-base balance • Calcium and phosphorus Stages of Chronic Renal Failure Changes (Continued) • Cardiac – – – – Hypertension Hyperlipidemia Congestive heart failure Uremic pericarditis • Hematologic • Gastrointestinal Clinical Manifestations Neurologic Cardiovascular Respiratory Hematologic Gastrointestinal Urinary Skin Hemodialysis Client selection Dialysis settings Works using passive transfer of toxins by diffusion Anticoagulation needed, usually heparin treatment Hemodialysis Nursing Care Postdialysis care: Monitor for complications such as hypotension, headache, nausea, malaise, vomiting, dizziness, and muscle cramps. Monitor vital signs and weight. Avoid invasive procedures 4 to 6 hours after dialysis. Continually monitor for hemorrhage Complications of Hemodialysis Dialysis disequilibrium syndrome Infectious diseases Hepatitis B and C infections HIV exposure—poses some risk for clients undergoing dialysis Peritoneal Dialysis Procedure involves siliconized rubber catheter placed into the abdominal cavity for infusion of dialysate. Types of peritoneal dialysis: Continuous ambulatory peritoneal Automated peritoneal Intermittent peritoneal Continuous-cycle peritoneal Complications Peritonitis Pain Exit site and tunnel infections Poor dialysate flow Dialysate leakage Other complications Nursing Care During Peritoneal Dialysis Before treating, evaluate baseline vital signs, weight, and laboratory tests. Continually monitor the client for respiratory distress, pain, and discomfort. Monitor prescribed dwell time and initiate outflow. Observe the outflow amount and pattern of fluid. Renal Transplantation Candidate selection criteria Donors Preoperative care Immunologic studies Surgical team Operative procedure Postoperative Care Urologic management Assessment of urine output hourly for 48 hours. Complications include: Rejection Acute tubular necrosis Postoperative Care Thrombosis Renal artery stenosis Other complications Immunosuppressive drug therapy Psychosocial preparation