http://www.scientistsatwork.be/files/imagecache/foto_group/files/mitosis_cartoon_1.jpg Amy Yu Biology Honours Specialist AQ Mentor: Andrew Smereczynsky “Quiz-Quiz-Swap!” Uses Benefits ◦ Find a partner, quiz each other, and then SWAP! ◦ As a social, enjoyable activity to review unit vocabulary ◦ To supplement Unit Test Review ◦ ◦ ◦ ◦ Engages variety of learners (visual, verbal, kinesthetic) Opportunities for student peer feedback Excellent formative assessment Empowers students to familiarize with accurate terms 10 Applied 10 Academic Cell cycle, Cell cycle including mitosis Mitosis in detail No meiosis covered No meiosis covered 11 College Differentiating between mitosis & meiosis Function of meiosis Including phases of mitosis 11 University No mitosis Meiosis in detail Including phases, random assortment, crossing over, and non-disjunction 1. Differentiating between mitosis and meiosis • Sex cells vs. somatic cells vs. body cells What are gametes and when are they created? • haploid vs. diploid cells • 2. Accurate vocabulary is required for accurate description of processes • • “allele” and “gene” are used interchangably “homologous pairs” often confused with “sister chromatids” or the ambiguous term “chromosomes” 3. Resources often do not depict a process, just a static picture of isolated stages /events •Does not depict mitosis or meiosis as a dynamic, ongoing process •Observing dead mitotic cells under a microscope presents similar problems http://www.le.ac.uk/ge/genie/vgec/images/mitosis_meiosis.png •Reinforces the misconception that cell division occurs in defined, isolated “stages” •Does not follow location of genes at different loci MISS!?!? I can’t see anything! http://www.biologycorner.com/resources/onionmitosis.jpg Bajema Strategy (Mertens & Walker, 1992) •Students use coloured pencils and draw 2 pairs of chromosomes •Genes (e.g. A/a or B/b) may be placed on them to trace their movement (great alternative to the Mendelian punnett square algorithm) •Sequence of events in meiosis is traceable Computer Animations The Stages of Mitosis http://www.youtube.com/watch?v=nPG6480RQo0&feature=related Meiosis http://www.youtube.com/watch?v=D1_-mQS_FZ0 Computer Simulations Cell Division Gizmo www.explorelearning.com Variety of manipulatives (pipe cleaners, magnetized chromosomes, etc.) Poor conceptual organization can impede grasp of future, related concepts ◦ Confusion about mitosis (Grade 10) can discourage students from learning meiosis in Grade 11 ◦ Meiosis and genetic inheritance should be taught together to emphasize their relatedness Isolated conceptual relationships are taught ambiguously and without connection to the overall picture ◦ Where do homologous chromosomes come from? (one comes from maternal gamete, other from paternal gamete) ◦ How are chromatid pairs formed? (DNA replication – Grade 12 concept) ◦ How are chromsomal reduction, allelic segregation, and gene assortment related? (these are often depicted separately with separate diagrams, leading students to believe these are isolated events) 4 stations = 4 “Tasks” 1 sock = 1 chromosome black clips = centromeres As you move through the 4 different “Tasks,” consider: ◦ ◦ ◦ ◦ grade/ level where “Task” could be used where student misconceptions could present themselves possible extensions how each “Task” differs from another Addresses 3 key events of cell division with which students often have errors: chromosome doubling, pairing, and separating Clarifies confusion between ploidy (# of sets of chromosomes) with chromosome structure, emphasizes the precision of the meiotic process A kinesthetic, verbal activity which can help both students and teachers identify early misconceptions before they survive and are reinforced Chinnici, Neth, and Somalin. “Using ‘Chromsomal Socks’ To Demonstrate Ploidy In Mitosis and Meiosis.” The American Biology Teacher (2006). 68(2):107. Individual or group activities that ask students to compare and contrast , differentiate, or make associations are excellent ways to catch early misconceptions and build each student’s confidence with genetics • • • Venn diagrams, T-charts Scrambled terms: place on “mitosis” wall or “meiosis” wall Students are given a term/ event and organize themselves into “Team Mitosis”, “Team Meiosis,” or both Teacher: Student: “Notice how during Metaphase I [in meiosis], the homologous pairs match up at the equator. This differs from metaphase in mitosis, where the sister chromatids line up at the equator.” (confused) “Aren’t homologous chromosomes and sister chromatids the same thing?” [After backtracking for the 3rd time this week, this lesson goes over time and/or is unfinished, much to the teacher’s delight] Foldables ABC’s Activity: Vocabulary Brainstorm Quiz-Quiz-Swap Word Walls Picture Cards Materials ◦ jerseys/ T-shirts of different colours (4 each) ◦ stockcards with terms or concepts to be covered Benefits ◦ low-cost materials ◦ engages all of the senses – appeals to auditory, kinesthetic, interpersonal and visual learners ◦ concrete learning of an abstract concept Extensions or Applications ◦ can be extended to demonstrate meiosis, mistakes in meiosis leading to polyploidy Causes of cancer, cancer treatments Stem cell research Cloning Genetic diseases arising from mistakes in meiosis (polyploidy), sex-linked diseases Fertility and other reproductive issues graphic organizers, collaborative learning activities, microscope labs Listen/watch for misconceptions, catch them early! Bajema strategy pencil-and-paper check Role Play Summary to ensure connection between physical activity and mental images of mitosis Possible Criteria to Evaluate Student Understanding of Cell Division • vocabulary • drawing or interpretation of phases • accurate labeling of structures • accurate depiction of sequential events Give students choice, differentiate possible products: • “Mitosis Booklet” or “Meiosis Booklet” • Comic strip – using Comic Life Technology • TV Script – TV skit • Animations • Poem or Song Hopefully this can be added to your teacher toolbox! Thank You!