Cell Division Chapter 14 Intro worksheet Why do cells divide in organisms? What are chromosomes? Where are chromosomes found? In pairs discuss 1. Why do cells divide in organisms? 2. What are chromosomes? 3. Where are chromosomes found? Aidhm Explain the terms: cell continuity & chromosomes. 2. Define the terms: haploid number & diploid number. 3. Describe the cell cycle in the state of non-division (Interphase) and division (mitosis). 1. Cell Cycle – flow chart 4 Cell Continuity Cell continuity: All cells develop from pre-existing cells It involves growth, synthesis and reproduction. Chromosome Structure 6 Chromosomes contain genes composed of DNA and proteins Chromosomes occur in pairs in most plant and animal cell nucleii. A gene is a short section of DNA. It is the unit of inheritance. It controls the development of a particular characteristic A gene has a particular locus (position) on a chromosome 7 Chromosomes When not dividing = Chromatin (long thin threads) When dividing = Chromatin forms a numbers of clearly distinguishable Chromosomes Each species has a definite no. of Chromosomes, Humans= 46 chromosomes Each Chromosomes has 1000s of genes How many chromosomes? Each species has a characteristic number of chromosomes. Humans have 46 23 from their mother 23 from the father A human has 23 pairs You have two of each type of chromosome. 12 Haploid A Haploid cell has one set of chromosomes has only one set of each type of chromosomes in the nucleus. Haploid is symbolised by letter ‘n’ and number of chromosomes in the cell is n=23 In humans, eggs and sperm are haploid n=23 Diploid A Diploid has pairs of chromosomes It has two of each type of chromosome in the nucleus These pairs of chromosomes in diploid cell are called homologous pairs. Diploid is symbolised as ‘2n’ and total no. of chromosomes in cell is 2n=46 • In diploid cells, 1 chromosome from the homologous pair comes from the mother and the other comes from the father. Cell Cycle Describes the life of a cell. Interphase = when cell is not dividing Mitosis = when cell divides Interphase Mitosis or Meiosis Interphase When cells are not dividing Longest phase in cell cycle Chromosomes elongated = chromatin What occurs during interphase New mitochondria Chloroplasts are produced Duplication of chromosomes occurs Learning Check 1. 2. 3. What 2 stages are involved in cell continuity, which is longest? What is meant by haploid and diploid? What is a chromosome, what is it made up of, what is it known as when not dividing ? How many chromosomes are found in a typical human cell, how many found in a gamete, what are the chromosomes for a male and a female? Can you….. Explain the terms: cell continuity & chromosomes. 2. Define the terms: haploid number & diploid number. 3. Describe the cell cycle in the state of non-division (Interphase) and division (mitosis). 1. 5-5-1 Deluxe! Back to Plenaries Now reduce that to 5 key words… Write 5 sentences summarising today’s topic… And finally to one word…. Use shapes and pictures to deluxe-ify 5-5-1 Aidhm 1. 2. 3. Define the term: mitosis. Explain the process of mitosis in simple terms, with the aid of diagrams to show chromosome behaviour. State the primary function of mitosis for single-celled and multicellular organisms. https://www.youtube.com/watch?fea ture=player_embedded&v=VlN7K19QB0 Mitosis Mitosis is a form of nuclear division in which one nucleus divides to form two nuclei. Each nucleus contains identical sets of chromosomes. Two new cells called daughter cells and they are IDENTICAL to each other. Mitosis A sentence to help you remember the 4 stages of mitosis I Interphase Party Prophase Monday Metaphase And Anaphase Tuesday Telophase THE CELL CYCLE Stages of Mitosis Stages of Mitosis Prophase • Spindle fibres begin to appear • Chromosomes contract and duplicate. The point where the strands are held together is called a centromere HL • The nucleolus (part of nucleus where ribosomes are made) breaks down • Nuclear membrane starts to break down Stages of Mitosis Metaphase • Nuclear membrane breaks down completely • Chromosomes contract even more • Chromosomes line up across the equator of the cell • Spindle fibres attach to the centromere of each chromosome. One fibre attaches from each end to every chromosome. Stages of Mitosis Anaphase • Spindle fibres contract • Centromere splits • One strand from each chromosome is pulled to either end of the cell. • The chromosomes at each end of the cell have identical set of genes • Shortest phase Stages of Mitosis: Telophase OL HL • Spindle fibres break down • Chromosomes elongate to from chromatin • When mitosis is complete, the cell divides into 2 cells which are identical. HL • One or more nucleolus begin to reform • Nuclear membrane forms around each of the 2 sets of chromatin Functions of Mitosis Unicellular Organisms Reproduction for Amoeba (Asexual reproduction). In Multicellular Organisms Produces new cells, not new individuals Responsible for growth Responsible for renewal and repair of cells Found in root and shoot tips of plants, buds Root tip of onion Can you…. 1. 2. 3. Define the term: mitosis. Explain the process of mitosis in simple terms, with the aid of diagrams to show chromosome behaviour. State the primary function of mitosis for single-celled and multicellular organisms. Aidhm Explain cell division in plants and animals in more detail 2. Define cancer and state two possible causes. 3. Define the term: meiosis. 4. State the functions of meiosis. 1. Cell Division HL 1. Animal Cells • Cell division occurs by cleavage • A cleavage furrow appears along the equator of the cell • It deepens and splits the cytoplasm 2. Plant Cells • Cell wall prevents cleavage furrow forming • Vesicles containing cellulose gather in the area between the 2 nuclei • The vesicles form a cell plate • The membrane of the cell plate joins the plasma membrane of the original cell • 2 cell walls form • Middle lamella = region between the 2 cell walls www.edcodigital.ie Animations of stages on chapter 14 Cancer A cell or group of cells lose the ability to control the rate of mitosis or cell division. They form a mass of cells called a tumour which can be benign or malignant. Cancer Benign tumours Benign means kind, not life threatening and do not invade other tissues. Eg warts, skin tags. Cells stop dividing after some time Malignant tumours Uncontrolled multiplication of abnormal cells Malignant tumours (cancers) invade other cells and move around the body Movement of these cells called Metastasis. Cancer cells divide indefinitely. Causes of Cancer Oncogenes: When normal genes are altered to form cancer-causing genes 1. Carcinogens (cancer causing): cigarette smoke, asbestos fibres, uv 2. Some viruses Learning Check 1. 2. 3. 4. 5. 6. What is the function of mitosis in multicellular organisms? What is the function of mitosis in unicellular organisms? How do tumours form? What is the difference between benign and malignant tumours? When cancer cells spread it is called m......................? Can you name 3 possible causes of cancer? Meiosis Meiosis A form of nuclear division in which the daughter nuclei contain half the number of chromosomes of the parent nucleus. Human cells have 46 chromosomes Meiosis occurs in the ovaries and testes to produce gametes called eggs and sperm so there are 23 chromosomes in each egg and sperm Meiosis in a diploid (2n) cell produces 4 haploid (n)cells Functions of Meiosis 2 functions in Multicellular Organisms Allows sexual reproduction without increasing the number of chromosomes in the offspring Allows new combinations of genes Meiosis Products of Mitosis & Meiosis compared Mitosis Meiosis 56 Mitosis Vs Meiosis (1/2) Resulting nuclei not identical – variation Daughter cells have half the no. of chromosomes as parent. Resulting nuclei identical No reduction in chromsomes One cell divides to form 2 One cell divides to form 4 57 4. 9 +8 +3(1) Example: The cells produced by meiosis are haploid T The cells produced by mitosis are identical T Meiosis gives rise to variation T Mitosis always produces four new cells F Meiosis is never involved in gamete formation F Single-celled organisms use mitosis for reproduction T Can you…. Explain cell division in plants and animals in more detail 2. Define cancer and state two possible causes. 3. Define the term: meiosis. 4. State the functions of meiosis. 1. WWTBM 1 END As easy as 1 2 3 Most human cells have 46 chromosomes There are 4 stages of mitosis Interphase is the longest part of a cell cycle