Cardiovascular, Lymphatic, & Immune Systems Review Organs of the Cardiovascular System: Blood vessels Heart – cone-shaped muscular pump located in the mediastinum. Pericardium (pericardial sac) – covering that encloses the heart. o fibrous pericardium – outermost covering. o serous membrane (double membrane) visceral pericardium – inner, close-fitting parietal pericardium – outer, loose-fitting Types of Circulation: Systemic circulation Pulmonary circulation Major Parts of the Heart: Chambers o right atrium o right ventricle o left atrium o left ventricle Valves o tricuspid (right A-V) valve o bicuspid or mitral (left A-V) valve o pulmonary valve o aortic valve Chordae tendineae Papillary muscles Walls of the Heart: Endocardium Myocardium Epicardium Major Types of Blood Vessels: Veins – contains valves; serves as a blood reservoir (holds the greatest volume of blood); contains less smooth muscle than arteries. Venules – small veins; connection between capillaries and veins. Capillaries – smallest blood vessels; blood flow through capillaries is controlled by precapillary sphincters. Functions in exchanging gases & nutrients between the blood and tissue cells. Arterioles – small arteries; connection between arteries and capillaries. Arteries – thickest blood vessels; has a thick smooth muscle layer. Aorta is the largest artery. Blood Pressure: Arterial systolic pressure (highest pressure) – occurs during ventricular (systole) contraction. Tricuspid & bicuspid valves close; pulmonic & aortic valves open. Arterial diastolic pressure (lowest pressure) – occurs during ventricular (diastole) relaxation. Tricuspid & bicuspid valves open; pulmonic & aortic valves close. Pulse pressure – calculated by subtracting diastolic pressure from systolic pressure. Cardiovascular Disorders: mitral valve prolapse atherosclerosis myocardial infarction heart murmurs Lymphatic System Functions: Lymphatic Pathways: lymphatic capillaries lymphatic vessels lymph node lymphatic trunk lymphatic duct Lymphatic Tissue: lymph node thymus gland spleen Innate Defenses: species resistance mechanical barriers fever chemical barriers natural killer cells inflammation phagocytosis Adaptive Defenses (Immunity): T cell functions B cell functions Immune Responses: Primary Secondary Classification of Immunity: Naturally acquired active immunity Artificially acquired active immunity Naturally acquired passive immunity Artificially acquired passive immunity