Name:_______________________ Exception to Mendel’s Laws Per:___________ Date:__________ Incomplete Dominance and Codominance In all of Mendel’s experiments, he worked with traits where a single gene controlled the trait and where one allele was always dominant to the other. Although the rules that Mendel derived from his experiments explain many inheritance patterns, the rules do not explain them all. There are in fact exceptions to Mendel’s rules, and these exceptions usually have something to do with the dominant allele. One exception to Mendel’s rules is that one allele is always completely dominant over a recessive allele. Sometimes an individual has an intermediate phenotype between the two parents, as there is no dominant allele. This pattern of inheritance is called incomplete dominance. An example of incomplete dominance is the color of snapdragon flowers. One of the genes for flower color in snapdragons has two alleles, one for red flowers and one for white flowers. A plant that is homozygous for the red allele will have red flowers, while a plant that is homozygous for the white allele will have white flowers. On the other hand, the heterozygote (offspring) will have pink flowers. Neither the red nor the white allele is dominant, so the phenotype of the offspring is a blend of the two parents. It is pink. Pink snapdragons are an example of incomplete dominance. An example of a co-dominant trait is ABO blood types, named for the carbohydrate attachment on the outside of the blood cell. In this case, two alleles are dominant and completely expressed (designated IA and IB), while one allele is recessive (i). The IA allele encodes for red blood cells with the A antigen, while the IB allele encodes for red blood cells with the B antigen. The recessive allele (i) doesn’t encode for any antigens. An antigen is a substance that provokes an immune response, your body’s defenses against disease, which will be discussed further in the Diseases and the Body's Defenses chapter. Therefore a person with two recessive alleles (ii) has type O blood. As no dominant (IA and IB) allele is present, the person cannot have type A or type B blood. There are two possible genotypes for type A blood, homozygous (IAIA) and heterozygous (IAi), and two possible genotypes for type B blood (IBi and IBIB). If a person is heterozygous for both the IA and IB alleles, they will express both and have type AB blood with both antigens on each red blood cell. This pattern of inheritance is significantly different than Mendel’s rules for inheritance because both alleles are expressed completely and one does not mask the other. Name:_______________________ Exception to Mendel’s Laws Per:___________ Date:__________ Questions: Answer using complete sentences below. 1) What are the two exceptions to Mendel’s Laws described in the article? 2) Compare the two exceptions. 3) In snapdragons, flower color is controlled by incomplete dominance. The two alleles are red (R) and white (W). The heterozygous genotype is expressed as pink. a) What is the phenotype of a plant with the genotype RR? ___________ b) What is the phenotype of a plant with the genotype WW? ___________ c) What is the phenotype of a plant with the genotype RW? ___________ 4) What phenotypes would you expect from a cross between a red bull (RR) and a white cow (WW) in codominance? Show the Punnett Square. 5) If two alleles are dominant and completely expressed (designated IA and IB), what is this blood group? 6) Give an example of incomplete dominance and complete dominance seen in the environment. Explain.