Managing the Magnet: A Prequel to Pressing the Scan Button Authors: J Patel MD, CM Glastonbury MBBS, D Arnold RT (MR), J Morel RT (MR), A Srinivasan MD Control #: 492 eEdE#: eEdE-80 ASNR 2015 Annual Meeting Disclosures The authors have no financial disclosures. Philips hardware is demonstrated in several cases because of the authors’ experience with Philips equipment at their institution. For detailed information regarding hardware set-up, usage and safety of their own scanner, viewers should refer to vendor product manuals and/or consult support staff. Plan Introduction to MR safety Discussion of coil types and advances Elaborate on time saving strategies in MR imaging The MR Environment The MR environment is the area around an MR scanner and can be hazardous, even deadly, if unsafe materials or devices enter it. It poses safety risks because of: Static magnetic field & spatial gradients Rapidly changing magnetic fields Rapidly changing radiofrequency (RF) pulses The highest risk areas are those within a 5 gauss (0.5 mT) magnetic field line of the scanner(s). FDA primer document (1997) How Can MR Harm? Static Magnetic Field (Always on) Rotational Forces i.e. Torque Translational Force (from spatial gradient) Gradient Magnetic Field Induced Currents TEARING OF TISSUE from device rotation Tearing of tissue or acceleration of object (MISSILE EFFECT) DEVICE MALFUNCTION FDA primer document (1997) How Can MR Harm? Induced Currents causing Heating BURNS (thermal or electric) Electromagnetic Interference (in objects with a power source) POSSIBLE DEVICE MALFUNCTION Radiofrequency Pulses MR Safety To delineate the area and maximize patient and personnel safety, the MR environment is divided into 4 safety zones. All patients and any non-MR personnel entering the MR environment must go through MR safety screening before passing beyond Zone 2. ACR guidance document on MR safe practices (2013) Zones 1 and 2 Zone 1 Freely accessible to general public. e.g. Hallway outside reception area. Magnetic fringe fields are < 5 gauss (0.5 mT), so there is no magnet-related hazard. Zone 2 Separates general public area (Zone 1) from areas under stricter control. Includes reception, waiting, and changing rooms. Patients are screened here, and are under the general supervision of MR personnel. Zones 3 and 4 (“The MR Environment”) Zone 3 Only authorized personnel and screened patients can enter - access should be physically restricted. MR control room is in this zone. Magnetic field may exceed 5 gauss (0.5 mT). Zone 4 DANGER This is the magnet room, and the most hazardous area due to the magnetic field strength. Screened patients must be under the constant supervision of personnel trained for Zone 4. Zone 4 Labeling All portable objects and devices taken into Zone 4 must be labeled following criteria developed by the American Society for Testing and Materials (ASTM) and used by the U.S. Food & Drug Administration (FDA). They should be classified as MR safe, MR conditional or MR unsafe before entering Zone 3. Never assume MR safety/compatibility without written documentation! Zone 4 Labeling MR SAFE *ASTM labeling used by FDA Objects that are wholly non-metallic and made from material known to be safe in the MR environment. MR CONDITIONAL Metallic objects that pose no hazard only if specific conditions are met. There are numerous condition categories. MR UNSAFE Objects that are hazardous due to ferromagnetism or other MR environment interactions (e.g. induced currents in looped leads) ACR guidance document on MR safe practices (2013) What is MR Conditional? Determining MR conditional status must be meticulous. There are multiple determinants of conditional safety beyond field strength (i.e. 1.5T vs. 3T). References for safety documentation should be used (e.g. www.mrisafety.com and www.magresource.com). What is MR Conditional? Specific Determinants of MR Conditional Status can include: Magnetic field strength Directionality of field (“open” vertical vs. closed horizontal) Time rate of change of the magnetic field Duration of active scanning Radiofrequency (RF) fields Specific absorption rate (SAR) Configuration of device and time since implantation www.mrisafety.com Specific Absorption Rate Specific absorption rate (SAR) is a measure of the deposition of electromagnetic energy in the body (units = watts/kilogram). FDA warns of significant risk for harm for whole body SAR > 4 W/kg averaged over 15 minutes, and head SAR > 3.2 W/kg averaged over 10 minutes. Devices can have different SAR conditional safety requirements. FDA guidance document (2014) Specific Absorption Rate For the Reveal XT Insertable Cardiac Monitor, head SAR must be ≤ 3.2 W/kg (matching FDA requirement). Image reproduced with permission of Medtronic, Inc. But note that whole body SAR must be ≤ 2.0 W/kg (stricter than FDA figure). Reveal XT product manual (2013) Safety: Closed vs Open Magnets Different inherent characteristics of closed and open magnets can have implications for safety. Closed and open magnets differ in the directionality of their maximum field gradient lines and spatial distribution of the field. A device could be conditionally safe for a 1.5 or 3 Tesla closed magnet, but actually unsafe for a 1.0 Tesla open magnet. Field orientation: Closed vs Open Classic cylindrical “closed” magnets have a horizontally-oriented maximum field gradient line centrally through the isocenter. “Open” magnets have a verticallyoriented maximum field gradient line centrally. Implication: Ferromagnetic objects might experience more rotational force (torque) in an open magnet Closed vs. Open Magnet The Reveal XT Insertable Cardiac Monitor is conditionally safe for closed bore, cylindrical magnets with static fields of 1.5 or 3 Tesla. Image courtesy of chestdevices.com It is unsafe for open vertical field magnets. Reveal XT product manual (2013) Spatial Gradients: Closed vs Open Closed cylindrical magnets: Maximum spatial gradient that could be encountered by a device varies between concentric circles from the isocenter. Open magnets: Maximum spatial gradient encountered varies along the height of the horizontal plane at which the object is positioned. Spatial Gradients: Closed vs Open The Multilink Ultra OTW coronary stent is confirmed conditionally safe for a maximum spatial gradient of 3.3 T/meter. In a 1.5 T closed Philips Achieva magnet a device positioned 20 cm from isocenter axis would encounter a 2.6 T/meter spatial gradient. This stent is Conditionally SAFE for the gradient at 20 cm from isocenter in this closed 1.5 T magnet In a 1.0 T open Philips Panorama magnet, the minimum spatial gradient would be at 20-22 cm above the table top, which would be 4.4 T/meter. This stent is UNSAFE for this open magnet b/c minimum gradient is too high www.magresource.com Philips technical description (2013) Managing the Magnet MR Radiofrequency (RF) Coils Radiofrequency Coils If the MR scanner is considered like a camera, then the RF coil would be the lens. RF coils determine the diagnostic field of view. The closer the coil is to the area of interest, the better the signal-to-noise ratio (SNR) will be. Generally, the smaller the coil, the better the SNR. Radiofrequency Coils Many RF coils used in neuroimaging only receive signals; they are “receive-only” coils. Receive-only coils use the body scanner to transmit signal; this gives uniform excitation throughout the area of interest, but it has the implication of higher whole body SAR. “Transmit/receive” RF coils can transmit and receive signal; they generate less whole body SAR, but have lesser field uniformity in the area of interest. Radiofrequency Coils Neuroimaging generally requires a combination of volume and surface RF coil configuration depending on anatomy being studied. Head Neck Cervical Thoracic Lumbar RF Coils: Brain Philips Achieva SENSE Head coil A volume design head coil permits imaging of the brain, and special protocols involving the orbits, pituitary, and brainstem, etc. Head Photo courtesy of Philips Healthcare RF Coils: Neurovascular + H/N A volume RF coil configuration (requiring an anterior component) permits adequate signal receipt for neurovascular and head/neck studies. Achieva SENSE Neurovascular coil Base Anterior component Photos courtesy of Philips Healthcare Neck C-spine RF Coils: Neurovascular + H/N Brachial plexus protocol. Coronal postcontrast T1-weighted images demonstrate a neoplastic lesion infiltrating the left lower MRA of the neck cervical nerve roots and trunks. Neck C-spine RF Coils: Spine A surface design posterior coil can be used for spine imaging. Achieva SENSE Spine coil Base component of neurovascular coil for cervical spine Photo courtesy of Philips Healthcare Spine RF Coils: Special Circumstances There can be circumstances where a routine RF coil set-up may be insufficient. Complete exam requires a configuration that provides optimal signal detection in the area of concern. For example, sacral pathology extending significantly into the pre-sacral region would be best performed with a dedicated pelvic coil rather than with a surface spine coil (e.g. sacrococcygeal teratoma or sacral chordoma). Special Circumstance: Pelvis The example below (left) shows a sacral chordoma that was imaged with a dedicated body coil (right) allowing the necessary visualization more anteriorly in the pelvis. Anterior part Axial T2-weighted fat-suppressed Posterior part Achieva SENSE Body Coil Photo courtesy of Philips Healthcare Open Magnet RF Coils Philips ST Body/Spine M Coil Open magnets (like the Philips Panorama HFO) can require volume design, with anterior and posterior components, for spine imaging. Photo courtesy of Philips Healthcare Integrated RF Coils Newer generation systems may have RF coils built-in, which decreases equipment set-up time. On the right is an example of a posterior surface coil built into the table. Ingenia Integrated Posterior Coil Photo courtesy of Philips Healthcare Multichannel RF Coils Multichannel receive-only coils have multiple elements arranged in a way that obtains signal uniformly from the imaged region. They provide improved image quality from increased signal-to-noise ratio and improved spatial resolution. Multichannel RF Coils 32-channel head coil used for a functional MRI exam Axial T1-weighted images demonstrate distinct optic tracts and sharp gray-white matter differentiation. Managing the Magnet Saving Time MR Scan Time Acquiring diagnostic quality images in a timely manner is essential due to increasing patient volumes and for patient comfort. Protocoling should be performed so that only the necessary sequences are performed to save time. However, technical improvements are ongoing to facilitate faster imaging and throughput. Parallel Imaging Parallel imaging (PI) technique is now a commonplace strategy for accelerated image acquisition. PI relies on the arrangement of multiple coil elements to obtain spatial information (from a reference scan) that is used for subsequent sequences. This enables an undersampling of k-space, and therefore faster imaging. Multichannel RF Coils Therefore, multichannel RF coils can provide increased image quality, but they also enable parallel imaging. Axial post-contrast T1-weighted images from a preoperative Stealth exam using a 32-channel RF coil. Compressed Sensing Compressed sensing (CS) is an emerging technique that accelerates imaging time by significantly undersampling k-space. It “compresses” the image with a unique coding transform that uses a sparse representation of the desired image. It requires that undersampling-related artifacts that would ordinarily be distinctly seen using a standard transform be instead noise-like (and indistinct) in the CS sparsifying transform domain. Lustig M et al. (2008) Compressed Sensing CS is ideal for MR sequences that are already “sparse” in their appearance. For example, MR angiography focuses on vascular structures, with poor (“sparse”) signal representation of the background tissue and structures, making it a good candidate for CS. Lustig M et al. (2008) MR Scan Time Streamlining equipment can also substantially reduce exam time. For example, integrated RF coils can obviate the laborintensive transfer, set-up, and removal of delicate heavy equipment, and therefore increase facility efficiency and throughput. The Philips Ingenia Integrated Posterior Coil within the scanner table is an example of a built-in “ready-to-go” RF coil that would save set-up time. Photo courtesy of Philips Healthcare Conclusion Thank you for your time. We hope that by viewing this exhibit, you were able to enhance your understanding of the essentials of MR coil technology, safety issues and timely scanning, all of which happen before the scan hits our workstations for interpretation. References Kanal E, Barkovich AJ, Bell C, et al. ACR guidance document on MR safe practices: 2013. J Magn Reson Imaging 2013; 37:501-530 "Information and terminology regarding The List." Retrieved from http://www.mrisafety.com/GenPg.asp?pgname=InfoAndTerminology U.S. Food and Drug Administration, Center for Devices and Radiological Health. (2014). Criteria for significant risk investigations of magnetic resonance diagnostic devices - Guidance for industry and Food and Drug Administration staff. Retrieved from http://www.fda.gov/RegulatoryInformation/Guidances/ucm072686.htm U.S. Food and Drug Administration, Center for Devices and Radiological Health. (1997). A primer on medical device interactions with magnetic resonance imaging systems. Retrieved from http://www.fda.gov/RegulatoryInformation/Guidances/ucm107721.htm Abbott. (2009). MULTI-LINK RX ULTRA and MULTI-LINK OTW ULTRA Coronary stent systems - Information for prescribers. Retrieved through www.magresource.com from http://www.doctordoctor.biz/pdf/abbott/EL2040635.pdf Medtronic. (2013). Reveal XT 9529 insertable cardiac monitor. Retrieved from http://manuals.medtronic.com/wcm/groups/mdtcom_sg/ @emanuals/@era/@crdm/documents/documents/contrib_092102.pdf GE Healthcare. (2005 Spring). RF coils…They’ve come a long way. MR Field Notes, 1(2), 1-4. Retrieved from http://mri-q.com/uploads/ 3/2/7/4/3274160/ge_fieldnotes_volume1-2_coils.pdf Philips Healthcare. (2013). Technical description: Achieva release 3.2 series, Panorama 3.2 series. Parikh PT, Sandhu GS, Blackham KA, et al. Evaluation of image quality of a 32-channel versus a 12-channel head coil at 1.5T for MR imaging of the brain. Am J Neuroradiol 2011; 32:365-373. Lustig M, Donoho DL, Santos JM, Pauly JM. (2008 March). Compressed sensing MRI. IEEE Signal Processing Magazine, 72-81. *Philips Healthcare, Medtronic and www.chestdevices.com have given their permission for their photographs/images to be used in this exhibit.