Digestive System Organization of the Digestive System The organs of the digestive system are divided into TWO main groups: The ____________________________________ – also called the gastrointestinal (GI) tract ___________________________ – teeth, tongue, salivary glands, liver, gallbladder, pancreas Gastrointestinal (GI) Tract A long, winding, continuous tube that extends from the ___________________________________ Averages about 9 meters (___________________) Consists of: _____________________________________________________________________ _______________________________________________________________________________ Accessory Organs Located either ___________ the alimentary canal or _________________ it Communicates by way of _______________ _________________ the organs of the alimentary canal in their functions Includes: _______________________________________________________________________ Digestive Processes Food needs to be turned into a ______________________________________________________ This needs to be done by: _______________________ reducing the food _______________________ reducing the food _______________________ the food into the blood through the intestinal wall Carried by blood to the __________________________ Digestive Processes ____________________________ Taking food into the mouth (mechanical) ____________________________ Chewing (mechanical) Salivary action (chemical) ____________________________ Swallowing (mechanical) ____________________________ Wavelike contractions that move food through the GI tract (mechanical) ____________________________ Passage of food molecules from GI tract into circulatory system (mechanical & chemical) ____________________________ Elimination of undigestible wastes (mechanical) SPECIAL FEATURES OF THE DIGESTIVE SYSTEM Peritoneum: serous membrane, lubricating tissue (pericardium of the heart, pleurae of lungs) Parietal Peritoneum: ________________________ of the abdominal cavity Visceral Peritoneum: ____________________________ Extensions of the Parietal Peritoneum ____________________________ – attaches liver to diaphragm & anterior body wall _______________________ – extends between liver and the lesser curvature of the stomach ______________________ – extends from greater curvature of stomach to transverse colon ______________________ – supports the intestine ______________________ – supports large intestine Wall Structure of the Alimentary Canal ________________ Mucous membrane that ______________________________ of the alimentary canal Consists of a thin layer of loose connective tissue & a small amount of smooth muscle in the external layer Major functions: _____________________________________________________ ___________________________________________________________________ ________________ External to the mucosa Composed of loose connective tissue, rich in blood vessels, lymphatic vessels, nerve endings, & small glands ________________ Smooth muscle that externally encircles the submucosa Thickened at certain points along the alimentary canal to ______________________ ____________________________________________________________ Provides the ________________ of food during mechanical digestion as well as the _______________ of food through the alimentary canal by ____________________ ________________ The ______________________________________ DIGESTIVE ORGANS Mouth Function: process of ____________________ (______________) Moistening of food with saliva begins process of __________________________ Accessory organs associated with mouth: ________________________________________ Space between tongue and palate is called ___________________________ Cheeks and lips are separated by a space called the vestibule Palate: forms the __________________________________ ________________________: hard, bony anterior part of oral cavity ________________________: muscular, posterior part, forms archway bordering pharynx ______________________: along both sides of the archway ______________________: extends from the archway in a downward projection Tongue Anchored to the floor of the mouth by a membranous fold extending from its midline along its undersurface, called the lingual ____________________ Contains ______________________________________________ and also help to provide friction for moving food Teeth Provide mastication Dentition: _________ different sets of teeth during normal development First set: appear at about 6 months, continue to erupt until all ___________________ are present by about 24 months Referred to as deciduous teeth Second set: appear between 6 and 12 years By the end of adolescence, all permanent teeth have erupted except for the third molars, or wisdom teeth (17 and 25 years) In a full set, there are ____________________________________ Types: _______________________ – pointed chisel (cutting) _______________________ – cone-shaped (serve as tearing tool) ______________________________________________ – broad, flattened surfaces (grinding) Tooth Structure _____________: visible part of tooth above the gum line _____________: buried below the gum line _____________: covers the crown – hardest substance in the body Salivary Glands Collection of accessory organs surrounding the mouth that secrete a fluid called saliva Saliva consists of ___________________________________________________________ Medium for dissolving soluble food molecules Solutes include mucus and enzymes Lysozyme destroys bacteria Salivary amylase ________________________________________________ Parotid Glands ___________________ salivary glands Located in front of and slightly below each ear between the skin of the cheek and the masseter muscle Secretes a _____________________ that is rich in __________________________ Submandibular Glands Located along the inner surface of the jaw in the floor of the mouth Secrete a more viscous fluid than parotids due to the mucus in their secretions Sublingual Gland Lies ___________________________ Secrete a _____________________________ fluid due to the abundance of mucus Digestion in the Mouth: Digestion begins here Mastication – ______________________________________________________________ Creates a __________________ Pharynx Chamber located ________________________________ extending from the internal nares to the larynx Its walls are composed of skeletal muscle ________________________________________ Divided into ________________________: nasopharynx, oropharynx, and laryngopharynx Function: transports food from ________________________________________ Plays an important role in the act of swallowing Act of Swallowing: Begins as food ____________________________________ from the mouth into the pharynx by the tongue _______________________________________ to keep food from entering the nasal cavity Followed by contraction of muscles in the wall of the pharynx, which moves the larynx upward as the epiglottis presses downward (__________________________) Muscles in lower pharynx relax, opening the passage into the ____________________ The food bolus is pushed into the esophagus and onward to the stomach by ______________________________, which begins in the pharynx and continues along the length of the esophagus Esophagus Muscular tube that extends from the pharynx to the stomach for about 25 cm (___________) Located ____________________________________ in the neck and upper thorax _________________________________________________________________________ _________________________________ (lower esophageal sphincter/ cardiac sphincter) near its union with the stomach Acts as a valve to ______________________________________ from the stomach Opens as peristaltic waves reach the stomach Stomach ______________________________ that is about 25 cm (10 inches) long and in most people can hold over 2 liters of food When empty, its inner linings form deep folds known as _______________ (ROO-JE) The convex lateral margin of the stomach is called the ______________________________ The greater omentum extends from the greater curvature The concave medial margin is known as the __________________________________ The lesser omentum extends from the lesser curvature Parts of the stomach _____________________ – small area surrounding the opening that receives food from the esophagus _____________________ – expanded region that bulges above the cardia; serves as a temporary holding area for food _____________________ – main part of the stomach; lies between the fundus and the pylorus _____________________ – narrowed, inferior region At the terminal end is the _____________________ Serves as a valve to control the movement of food from the stomach to the small intestine Stomach Wall – MUCOSA Characterized by millions of tiny openings that can be seen only with a magnifying lens or microscope called gastric pits Gastric pits lead into tube-like gastric glands that secrete a collection of chemicals called _____________________ _____________________ of gastric juice pour out from these glands each day Glands contain secratory cells called _____________________________, which secrete digestive enzymes ___________________________________________________________________ Mucous cells secrete __________________ _________________ will develop if this lining breaks down Functions of the Stomach: Mechanical Digestion – accomplished by mixing and churning actions Chemical Digestion – provided by gastric juice Several enzymes are present, but most importantly, _______________ is present – secreted by zymogenic cells in an inactive form called pepsinogen Pepsin is a powerful _________________________________ capable of beginning the breakdown of nearly all proteins Pepsin and its acidic environment are kept from digesting the stomach wall by the protective layer of mucus that coats the ________________________ Absorption Limited amount of absorption takes place across the stomach lining Materials the can cross this barrier are: ____________________________________ ___________________________________________________________________ Propulsion Provided by _____________________________________________ The material that is ready to enter the small intestine has been converted by mechanical and chemical digestion into a semi-fluid paste of small food particles and gastric juice known as ______________________ Additional role of the stomach: Secretes a substance called _____________________, which _________________________ _______________________________________________________________ (vital for survival due to its role in the production of mature red blood cells) Pancreas An accessory organ of the digestive system and has an ______________________ function Soft, oblong organ that lies _____________________________________________ in the upper abdominal cavity Extends across the abdomen from its ____________ near the duodenum to its __________, which touches the spleen – middle portion is the _______________ Within the pancreas are groups of exocrine secretory cells called ______________ The secretory cells release a mixture of enzymes known as ___________________________ into the duct The ducts from all the acini drain into the pancreatic duct, which fuses with the ___________ _______________________ before entering the small intestine Scattered among the acini are clusters of endocrine cells called the _____________________ _______________________, which contain the cells that produce the hormones _________ _________________________________ and release them right into the blood Functions of the pancreas Digestive function of the pancreas is the secretion of pancreatic juice, which finds its way into the duodenum of the small intestine In an average adult, about 1500mL of this watery, clear fluid is produced daily The pancreatic enzyme responsible for digesting carbs is known as _____________________ The enzyme that aids in the digestion of fats is called _____________________ The enzymes that digest nucleic acids are called _____________________ Liver ____________________ visceral organ of the body Occupies the _____________________ of the abdominal cavity and presses against the diaphragm Like the pancreas, the liver is associated with the small intestine by way of the common bile duct One of its primary functions is the production of _______ that is necessary in ____________ ____________________________________ Structure of the Liver Divided into two main sections, called _______________ The large right lobe and the smaller left lobe The falciform ligament, a fold of the peritoneum, separates the right and left lobes and suspends the liver from the diaphragm and anterior abdominal wall Each lobe is further divided into numerous liver lobules Liver cells, which are known as ____________________________, are arranged within each liver lobule into columns that converge toward a central vein Columns are separated from adjacent columns by channels lined with endothelial cells These channels are filled with flowing blood and are called _______________________ ___________________ remove bacteria arriving with blood from the digestive tract Bile canaliculi carry a fluid secreted by hepatocytes known as ___________ Bile is a _______________________________ that contains water, bile salts, bile pigments, cholesterol, and electrolytes Functions of the Liver Digestive role of the liver is the _____________________ Emulsification – breaking apart clumps of _____________________ into tiny droplets HDL (high density lipoproteins) – _______ lipoproteins LDL (low density lipoproteins) – ___________________, can cause health problems Gallbladder The gallbladder is a small, thin-walled sac that serves as an accessory organ associated with the liver It is located immediately behind the liver, where it lies in a shallow depression tucked in against the lower margin of the right lobe The main function of the gallbladder is to ________________________________________ _______________________________________________________________ Small Intestine Body’s ________________________________ digestive organ It completes the processes of mechanical and chemical digestion, and is the ______________ _______________________________________________________________ Longest segment of the alimentary canal Extends from the stomach to the large intestine for about 6 m (_____________) It is 2.5cm (_____________) in diameter Suspended in the abdominal cavity by the _____________________, which anchors it to the abdominal wall It is framed by the large intestine Has three segments: duodenum, jejunum, and ileum Segments of the Small Intestine _____________________ Receives chyme from the stomach through the pyloric sphincter Only about 25cm (10 inches) long and is relatively immovable At the distal end of the duodenum, the small intestine continues as the more mobile jejunum _____________________ Extends for about 2.5m (8 feet) to the third segment, the ileum _____________________ Longest segment at about 3.6m (12 feet) It unites with the large intestine at the _____________________, which helps regulate the flow of material from the ileum to the large intestine Small Intestine Wall Mucosa Extremely __________________________________________________________ Has tiny projections known as intestinal ____________ Villi project about 1mm into the lumen of the small intestine where they come in contact with its contents Covering each villus is the mucosa, whose cells are bristled with thousands of tiny microprojections called ________________________ Within each villus are capillaries and a lymphatic vessel (called a lacteal), which carry absorbed nutrients away with blood Submucosa Contains numerous lymphatic nodules, known as _____________________, which protect the body against infectious microorganisms that try to penetrate the intestinal wall Also contains a collection of mucous glands, called __________________________, found only in the duodenum – help _______________________________________ Functions of the Small Intestine Chemical Digestion ____________________________________ by using a mixture of enzymes and bile Receives a wide spectrum of pancreatic enzymes from the pancreas and bile from the liver by way of the common bile duct Breaks down a wide spectrum of food (maltase, lactase, sucrase, and dextrase – all digest monosaccharides, which are carbs) Absorption Small intestine is the main site of nutrient absorption Effectiveness is due to the vast surface area of its mucosa (villi) Carb digestion begins in the mouth and ends in the small intestine Protein digestion by pepsin in the stomach and later in the small intestine by enzymes from the pancreas and intestinal mucosa results in the availability of amino acids Fat digestion occurs by the action of bile salts and enzymes within the small intestine Propulsion The propulsion of chyme through the small intestine is done by peristalsis Slow propulsion that takes between _____________________ to move chyme all the way through Large quantities of water and electrolytes are also absorbed by the villi Out of ____ liters of water, only _____ passes through to the large intestine If infection occurs, peristaltic contractions may dramatically increase, causing a very rapid movement of material through it, __________________________ Large Intestine Extends about 1.5m (_____________) from its union with the small intestine at the _______ __________________________________________ Its large diameter, which measures about 7cm (almost _____________), provides it with its name The main functions of the large intestine are to ____________________________________ by absorbing water, and to __________________________________________ Structure of the Large Intestine Divided into 4 main segments ____________________: receives material from small intestine Attached to the cecum is the _______________________ Colon: ____________________________________________________________ _______________________________________________________________ Rectum: located against the sacrum in the pelvic cavity; extends downward as a straight tube until it converges with the last segment of the large intestine, the anal canal Anal canal Wall of the Large Intestine Its mucosa _____________________ that are found in the small intestine In the mucosal lining are _____________________________________________________ to allow for easy passage of fecal matter Muscular structure is called _____________________ The propulsion of feces through the large intestine and out through the anus is called _____________________ It normally takes _____________________ for material to pass through the 1.5m of the colon, whereas it takes only 3 – 10 hours to pass through the 6m of the small intestine