4/5 2.3 Carbon-Based Molecules KEY CONCEPT Organic molecules are the foundation of life. 4/5 2.3 Carbon-Based Molecules Objectives • Identify what makes an organic molecule “organic” • Identify/Recognize carbon skeletons & functional groups in organic molecules • Relate monomers to polymers • Describe the processes of building and breaking polymers (2 reactions involved) • Describe the basic structure and function of carbohydrates, lipids, proteins, and nucleic acids 2.3 Carbon-Based Molecules Introduction to Organic Biomolecules!!!! Directions: While you watch this video, please answer the questions on the worksheet. • Biological Molecules - You Are What You Eat: Crash Course Biology #3 - YouTube 2.3 Carbon-Based Molecules Organic Molecules • Organic Molecules – Carbon-based molecules – Carbon forms covalent bonds with up to four other atoms, including other carbon atoms as it tries to fill its outermost energy level. • Hydrocarbons – Organic molecules made of only carbons and hydrogens (example CH4) • Inorganic Molecules – Non-carbon based molecules – Examples: H20, NH3, O2 4/5 2.3 Carbon-Based Molecules Carbon atoms have unique bonding properties. • Carbon-based molecules have three general types of structures. 1. straight chain 2. branched chain 3. ring 2.3 Carbon-Based Molecules Functional Groups on Organic molecules Functional Group – group of atoms within a molecule that interact in predicable ways with other molecules. 4/5 2.3 Carbon-Based Molecules Polymers vs Monomers • Many carbon-based molecules are made of many small subunits/peices bonded together. – Monomers are the individual subunits/pieces – Polymers are made of many monomers. 4/5 2.3 Carbon-Based Molecules Monomers bond together to build Polymers • Each time a monomer is added to a chain a water molecule is released (dehydration reaction) • Each time a monomer is broken from a chain a water molecule is added (hydrolysis reaction) Dehydration Rxn Hydrolysis Rxn 2.3 Carbon-Based Molecules Dehydration Reaction (Lose Water) when adding monomers to the polymer 2.3 Carbon-Based Molecules Hydrolysis Reaction (add water) when breaking polymers 4/5 2.3 Carbon-Based Molecules Four main types of organic molecules are found in living things 1. Carbohydrates (5.2) 2. Lipids (5.3) 3. Proteins (5.4 & 5.5) 4. Nucleic Acids 4/5 2.3 Carbon-Based Molecules Carbohydrates • Carbohydrates are made of carbon, hydrogen, and oxygen (Ratio= 1C:2H:1O) • Are made up of monomers of simple sugar molecules • The building blocks (simple sugar monomers) of carbohydrates are ring-shaped. 4/5 2.3 Carbon-Based Molecules Three Types of Carbohydrates Monosaccharide Disaccharide Polysaccharides 4/5 2.3 Carbon-Based Molecules – Carbohydrates include 1. Sugars 2. starches. – Monosaccharides are simple sugars. (ex: glucose) – Disaccharides are made up of two monosaccharides (ex: sucrose) – Polysaccharides include starches, cellulose, and glycogen. (ex: found in pasta & potatoes) 4/5 2.3 Carbon-Based Molecules Functions of Carbohydrates: 1. Carbohydrates can be broken down to provide energy for cells ( this requires water: Hydrolysis Rxn) 2. Some carbohydrates are part of cell structure (provide support) Starch is a Polymer (starch) Polymer (cellulose) monomer polymer of glucose monomers that often has a branched structure. Cellulose is a polymer of glucose monomers that has a straight, rigid structure 2.3 Carbon-Based Molecules Warm-Up 1. What are the monomers of Carbohydrates? 2. List the 3 different types of carbohydrates and give an example of each. 3. Which carbohydrate is found in plant cells? 4/5 2.3 Carbon-Based Molecules Lipids are nonpolar molecules that include fats, oils, and cholesterol. – Lipids are Hydrophobic molecules “water fearing” – Example (oil and water don’t mix) – Many contain carbon chains called fatty acids. – Fats and oils contain: – fatty acids bonded to glycerol. 2.3 Carbon-Based Molecules Lipids Structure Close-Up: - Glycerol - fatty acid chains 4/5 2.3 Carbon-Based Molecules • Fats and oils have different types of fatty acids. – saturated fatty acids (bad for you) – unsaturated fatty acids 4/5 2.3 Carbon-Based Molecules • Lipids have several different functions. – broken down as a source of energy – make up cell membranes (phospholipids) – used to make hormones 4/5 2.3 Carbon-Based Molecules • Phospholipids make up all cell membranes. – Polar phosphate “head” – Nonpolar fatty acid “tails” Phospholipid Hydrophillic Hydrophobic 2.3 Carbon-Based Molecules A closer look at phospholipid orientation in cell membranes: 2.3 Carbon-Based Molecules Steroids • Steroids are lipid molecules that form 4-Ring structures • Function: Act as chemical signals in our bodies – Example: Testosterone & Estrogen sex hormones – Example: Cholesterol (in cell membranes) 2.3 Carbon-Based Molecules Warm - Up Lipids are hydrophobic and nonpolar. What do those words mean? Hydrophobic = fear of water Nonpolar = no charged areas • What is the name of the lipids that make up cell membranes? phospholipids • What is the general structure of steroids? 4 connected Closed-Rings 4/5 2.3 Carbon-Based Molecules • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. Parts of an amino acid: 4/5 2.3 Carbon-Based Molecules • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. 2.3 Carbon-Based Molecules Building a Protein Polymer • How would you put these amino acid monomers together to form a protein polymer? 4/5 2.3 Carbon-Based Molecules • Proteins are polymers of amino acid monomers. – Twenty different amino acids are used to build proteins in organisms. – Amino acids differ in side groups, or R groups. – Amino acids are linked by peptide bonds. 2.3 Carbon-Based Molecules Polypeptides • Polypeptides are the result of joining many amino acid monomers 4/5 2.3 Carbon-Based Molecules • Proteins differ in the number and order of amino acids. – Amino acids interact to give a protein its shape. Hemoglo bin hydrogen bond – Incorrect amino acids change a protein’s structure and function. – Denaturation – proteins loose their shape in unfavorable conditions (temperature or pH) 2.3 Carbon-Based Molecules Warm-Up: Organic Molecules Review • List the 4 types of organic molecules • Monomers of carbohydrates? • Two main functions of carbohydrates? • Examples of Carbohydrates? • Lipid that makes up cell membranes? • Two types of Fatty Acids in lipids? 2.3 Carbon-Based Molecules Warm-Up • What are the building blocks of Proteins? • What are the 4 main parts of an amino acid? • What part of an amino acid give it it’s identity? • What reaction puts amino acids together? What happens during that reaction? • What special type of bond links amino acids? 2.3 Carbon-Based Molecules Enzymes • Many chemical reactions occur inside cells Reactants products • Enzymes are protein catalysts that speed up reactions by lowering the activation energy needed to start a reaction. • Activation Energy -The energy needed to start up a reaction • Catalyst – any compound that speeds up a reaction by lowering the activation energy 2.3 Carbon-Based Molecules Enzymes are never ‘used up’ • Enzymes are reaction specific • Substrate – reactant • Active site – groove area where substrates attach to enzyme • Enzymes always pick up another substrate when the active site is unoccupied!! • Enzyme Animation YouTube 2.3 Carbon-Based Molecules Enzymes Speed Up Chemical Reactions • They are able to do this by LOWERING the activation energy of a reaction. 2.3 Carbon-Based Molecules A reaction utilizing an enzyme = catalytic reaction Activation Energy is lowered! 4/5 2.3 Carbon-Based Molecules • Nucleic acids are polymers of monomers called nucleotides. 4/5 2.3 Carbon-Based Molecules • Nucleic acids are polymers of monomers called nucleotides. – Nucleotides are made of a: - sugar - phosphate group - nitrogen base A phosphate group deoxyribose (sugar) nitrogen-containing molecule, called a base 4/5 2.3 Carbon-Based Molecules • Nucleic acids are polymers of monomers called nucleotides. – Nucleotides are made of a sugar, phosphate group, and a nitrogen base. – DNA stores genetic information. DNA RNA – RNA builds proteins.