1 Are Your Bugs on Drugs ? A Cooperative Pharmaceutical Control Program in Petoskey, Michigan MWEA Wastewater Operators Fall Seminar September 16 and 30, 2009 2 (Photo Credit: Robert Morris, Harbor Springs Sewer Authority) 3 John Porter, P.E. 4 Over the last 70 years, we have benefited from new drugs and other products in our quest for “better living through chemistry.” A Water Environment Federation paper estimate: 80,000 different chemicals were released into the environment over this time. 5 Some entry routes to surface and groundwater - treated domestic/industrial wastewater, combined sewer overflows, septic tanks, concentrated animal feeding operations. As of 2006, nearly 28 million organic and inorganic substances have been inventoried. 6 “Emerging Contaminant” (a.k.a., “micro constituent”) Biological material or chemical substance synthetic or naturally occurring. Not routinely monitored in the environment. May already be present in the environment. Pollutants which may be candidates for future regulation, depending on potential human health effects and toxicity. Presence and effects becoming known or “emerging.” 7 Pharmaceuticals and personal care products: ◦ pharmaceuticals: antibiotics, hormones, statins, anti-cancer drugs, veterinary drugs. ◦ personal care: sunscreens, colognes, antibacterial soap, hair spray. Endocrine disruptors. Disinfection by-products. Brighteners in detergents. Anti-bacterial nano materials. 8 “Endocrine Disruptors” are: Substances that mimic a hormone in the endocrine system and disrupt the function of the hormone. ◦ Linked to biological effects in animals. ◦ May stimulate growth or cause underproduction of hormones. ◦ Concern: low-level exposure may cause similar effects in humans. 9 DDT. Bisphenol A (BPA) – plastic water bottles, white vegetable can liners. Estrogenic substances - birth control pills. Pthalates - in toys and air fresheners. Fire retardants. 10 11 12 Fish Upstream WWTP Effluent, (%) Downstream WWTP Effluent (%) Male 50 10 Female 50 80 Intersex 0 10 13 Antibacterial agent invented by Ciba in the1960s. In 2006, was found to interfere with endocrines in animals at levels in streams. Bacteria develop resistance to triclosan (Levy, 2001) and multiple antibiotics. Interferes with bullfrog thyroid function. 14 The American Medical Association cautioned against household use in 2002. Found in fish tissue, human breast milk, blood, streamwater/sediment, biosolids application sites, and wastewater. Contained in a large number of products. 15 11 Liquid Soaps Dial® Liquid Soap 7 deodorants Right Guard Sport 3 Dental Care Products Colgate Total® Tooth Paste Reach® Antibacterial Tooth Brush Colgate Breeze™ Mouthwash 5 Kitchenware Products Faberware® Microban Steak Knife Set and Cutting Boards Franklin Machine Products FMP Ice Cream Scoop with Microban SZ 20 10 PLAYSKOOL® Children’sToys 16 (source: www.wikipedia.org) 17 (source: www.wikipedia.org) 18 Acinetobacter baumanni—also called Iraqibacter because of its high incidence in American soldiers wounded in Iraq. Resistant to a large number of antibiotics. Acquired in the hospital. Treatment is quite difficult and expensive. It involves a new generation of antibiotics, which fortunately act on the bacterium. 19 20