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COURSE CONTENT:
CTBS prepares first-year medical students and second-year pharmacy students for some of the more challenging subjects in the School of Medicine’s Integrated Scientific Curriculum (ISC) through interactive lectures, teambased learning sessions, and frequent assessments with feedback. The subjects covered in CTBS (cardiovascular and respiratory anatomy and physiology, physiology and pharmacology of the autonomic nervous system, immunology, molecular biology, and genetics) are taught within several courses of the upcoming year’s curriculum, especially those in the first few months. Training in study strategies, time and stress management, and test-taking skills are integrated into the CTBS course to help students develop techniques to improve their experience in the ISC.
The topics taught in CTBS are organized into four threads for testing – cardiopulmonary physiology (CP), immunology (IMM), molecular genetics (MG), and anatomy and histology (A&H). The cardiopulmonary physiology thread, which includes autonomic physiology and pharmacology, is taught concurrently with immunology and molecular genetics, which gives students valuable experience in prioritizing study time between multiple courses (and exams). Such prioritizing and course juggling is a major challenge for many students.
EXAM SCHEDULE:
All exams consist of some combination of multiple-choice, matching, and constructed-response questions.
Exam descriptions and times are subject to change during the course; any changes will be announced in class and via e-mail. Each student is responsible for checking their UCSD email address daily (M-F).
Exam
CP exam I
IMM final
Day, date time Lectures covered by the exam
IMM exam I M 7/7
8 – 9:30 am
M 7/14
8 – 10 am
M 7/21
8 – 10 am
First 14 hours of Immunology (lectures IMM 1 – IMM 7)
First 26 hours of Physiology (lectures CP 1 – CP 13)
Cumulative exam covering all 24 hours of Immunology (lectures
IMM 1 – IMM 12); for medical students, the exam also includes
ANAT 4.
Physiology lectures CP 14 – CP 23 (20 hours) CP exam II
A&H practice practical exam
M 7/28
8 – 9:30 am
Tu 7/29
1 – 2:30 pm
Medical students
A&H practical exam
MG exam
CP final
Th 7/31
1 – 2:30 pm
M 8/4
8 – 10:10
F 8/8
9 - noon
Medical students – covers all A&H labs (1 – 5)
All 24 hours of Molecular Genetics (lectures MG 1 – MG12)
Cumulative exam covering all 60 hours of Physiology (lectures CP
1 – CP 30)
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COURSE REQUIREMENTS:
Successful completion of CTBS will result in a “P” for the course on the student’s transcript and requires all of the following:
1) Attendance and participation in team-based learning sessions; attendance at all lectures is strongly recommended.
2) Completion of all six written exams for pharmacy students, and of all six written exams and the A&H practical exam for medical students at their scheduled times – unless an alternative has been previously arranged with the course director.
3) Satisfactory progress toward achievement of the learning objectives for the course, which will be assessed with six exams. For each exam, a student can demonstrate satisfactory progress by either earning a passing score on the exam OR satisfactorily completing a written remediation assignment by its deadline. a. Passing score for the exam: Following each exam, the CTBS instructors will set a passing score of
75% or lower . A score ≥ 75% thus guarantees a student will pass any exam, but a lower score may pass a given exam. b. Remediation: Students must be present in person for all needed meetings with the instructor for satisfactory completion, including any meetings during the 8 th remediation week of the course. i) A student whose score falls below the passing score will meet with an instructor to discuss the exam, and be given a custom written remediation assignment with a deadline for that assignment. ii) After completing the assignment, the student will again meet with the instructor prior to the deadline to discuss the assignment. iii) Completion of the remediation assignment to the instructor’s satisfaction by the deadline will earn the student a passing score on that exam.
4) Completion of an anonymous online course evaluation.
HIGHLY RECOMMENDED TEXTS that are also used in the ISC courses – available from Amazon.com.
Anatomy:
Gray’s Anatomy , Drake, R. et al., 2 nd edition, 2009.
Immunology:
Basic Immunology : Funtions and Disorders of the Immune System , Abbas, A., and Lichtman, A., 4 th edition, 2012.
Respiratory Physiology:
Respiratory Physiology – The Essentials , West, John B., 9 th edition, 2011.
ONLINE RESOURCES – these are useful supplemental texts available online.
Cardiopulmonary Physiology:
Cardiovascular Physiology , Mohrman and Heller, 7 th edition is available through Access Medicine.
Ganong’s Review of Medical Physiology , 24 th edition is available through Access Medicine.
Autonomic Physiology and Pharmacology:
Basic and Clinical Pharmacology , Katzung, 12 th edition is available through Access Medicine.
Molecular Biology and Genetics:
PubMed Bookshelf, accessible through the Biomedical Library’s Online Clinical Library; both have useful diagrams for many of the molecular biology topics.
Molecular Biology of the Cell, Alberts, et al., 4 th edition, 2002.
Molecular Cell Biology, Lodish, et al., 4 th edition, 2000.
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Genetics Home Reference at http://ghr.nlm.nih.gov
/ contains a number of useful references for Genetics topics, including a glossary and search feature.
For those who prefer a Genetics text,
Thompson and Thompson’s Genetics in Medicine, 7 th edition is the most useful; it is not online, although selected excerpts can be seen through Google Books.
Histology:
Medpics at http://medpics.ucsd.edu
contains a library of histological images with commentary and mouseover tags for identification and self-assessment.
Junquiera’s Basic Histology, Mescher, 13 th edition, is available through Access Medicine
2014 Summer Session Deadlines
(listed as School of Medicine course SOMI 220 on UCSD Summer Session calendar available at
- open any one of the “Varies by Class” links on the Calendar and find SOMI 220 under “School of Medicine” heading near the bottom of pdf)
Course
SOMI 220 (CTBS)
Late enrollment period with $100 late fee
6/24-7/9
Last day to drop without
W on transcript
7/21
Last day to drop class with W on transcript (rather than F)
8/18
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All classes will be held in Skaggs Pharmaceutical Sciences Building Room 1160 (PSB 1160) unless otherwise noted on the schedule.
Anatomy and histology laboratory classes (A&H) will be held in MDL 2 in the Biomedical Sciences Building (MDL 2).
Day Time Topic Instructor
Week 1
Monday
June 23
Tues
June 24
Wed
June 25
Thurs
June 26
Fri
June 27
8:00-9:00 Introduction to CTBS
9:00-9:45 Study Strategies for Medical/Pharmacy School
10:00-12:00 CP 1 : Introduction to Physiology
8:00-10:00 CP 2 : Pressure, Resistance and Flow in Circulations
10:15-12:15 IMM 1 : Introduction to Immunology
1:00-2:30 A&H 1 : Cardiovascular System (MDL 2)
8:00-10:00 CP 3 : Venous Flows and Local Circulations
10:15-12:15 IMM 2 : Antigen Receptors
1:00-2:30 Biomedical Library Registration and Orientation
8:00-10:00 IMM 3 : Sites of Immune Responses
10:15-12:15 CP 4 : Smooth and Cardiac Muscle
12:30-2:00 Deans’ Luncheon (PSB 1186)
8:00-10:00 CP 5 : Autonomic Nervous System 1
10:15-12:15 IMM 4 : Overview of Adaptive Immune Responses
Week 2
Monday
June 30
Tues
July 1
Weds
July 2
Thurs
July 3
8:00-10:00 CP 6 : Autonomic Nervous System 2
10:15-12:15 IMM 5 : Hematopoiesis and Intro to BCR Gene Expression
8:00-10:00 IMM 6 : B-cell and T-cell Development
10:30-12:30 CP 7 : Cardiac Cycle 1
1:00-2:30 A&H 2 : Heart (MDL 2)
8:00-10:00 IMM 7: T-Cell Activation and Tolerance
10:15-12:15 CP 8 : Cardiac Cycle 2
8:00-10:00 CP 9 : TBL: Application of Cardiac Cycle (Murmurs, Drugs)
Fri
July 4
10:15-12:15 Review for Immunology Exam I
HOLIDAY
Week 3
Monday
July 7
Tues
July 8
Weds
July 9
Thurs
July 10
Friday
July 11
8:00-9:30 IMMUNOLOGY EXAM I
10:15-12:15 CP 10: Autonomic Nervous System 3
1:00 – 2:00 Review of Immunology Exam (Optional)
8:00-10:00 CP 11: Ventricular Function 1
10:15-12:15 IMM 8 : B-Cell Activation and Tolerance
1:00-2:30 A&H 3 : Autonomics (MDL 2)
8:00-10:00 CP 12 : Ventricular Function 2 and Cardiac Output 1
10:15-12:15 IMM 9 : Peripheral Tissue Microbial Infections and
Hypersensitivities
8:00-10:00 CP 13 : Cardiac Output 2
10:15-12:15 IMM 10 : Visceral Responses and Hypersensitivities
8:00-10:00 CP 14 : Electrophysiology 1
10:30-12:30 Review for Physiology Exam
N. Laiken
A. Apperson
P. Kingston
A. Apperson
A. Apperson
P. Kingston
A. Apperson
A. Apperson
K. Heskett
A. Apperson
P. Kingston
S. Schneid
A. Apperson
S. Schneid
A. Apperson
A. Apperson
P. Kingston
P. Kingston
A. Apperson
P. Kingston
S. Schneid/
P.Kingston
A. Apperson
A. Apperson
S. Schneid
A. Apperson
S. Schneid
A. Apperson
P. Kingston
S. Schneid
K. Brandl
S. Schneid
A. Apperson
S. Schneid
S. Schneid
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Monday
July 14
Week 4
8:00-10:00 PHYSIOLOGY EXAM I
10:15-12:15 CP 15 : Electrophysiology 2
1:00-2:30 Review of Physiology Exam (Optional)
Tues
July 15
Weds
July 16
Thurs
July 17
Friday
July 18
Monday
July 21
Tues
July 22
Weds
July 23
Thurs
July 24
Friday
July 25
8:00-10:00 IMM 11: Vaccines and T-cell Responses
10:15-12:15 CP 16 : Lung Structure and Function
1:00-2:30 A&H 4 : Blood (MDL 2)
8:00-10:00 IMM 12 : Allogeneic Responses and Organ Transplant Rejection
10:15-12:15 CP 17 : Pulmonary Blood Flow
8:00-10:00 MG 1 : DNA and Chromosomes
10:15-12:15 CP 18 : Ventilation and Diffusion
8:00-10:00 CP 19 : Reflex Responses to Baroreceptor and Chemoreceptor
Stimuli 1
10:15-12:15 MG 2 : Autosomal Inheritance
1:00-2:30 Review for Immunology Exam (Optional)
Week 5
8:00-10:00 IMMUNOLOGY FINAL EXAM
10:15-12:15 CP 20 : Reflex Responses to Baroreceptor and Chemoreceptor
Stimuli 2
1:00-2:30 Review of Immunology Exam (Optional)
8:00-10:00 MG 3 : X-Linked Inheritance and Population Genetics
10:15-12:15 MG 4 : Conditional Probabilities (Bayes)
1:00-2:30 A&H 5 : Lungs and Pleura (MDL 2)
8:00-10:00 MG 5 : TBL 1: Genetics
10:15-12:15 CP 21 : Gas Transport in Blood
8:00-10:00 MG 6 : mRNA Transcription and its Regulation
10:15-12:15 CP 22 : Acid-Base Balance
8:00-10:00 MG 7 : mRNA Processing
10:15-12:15 CP 23 : Acid-Base Problem Set
1:00-2:30 Review for Physiology Exam
Monday
July 28
Week 6
8:00-9:30 PHYSIOLOGY EXAM II
10:15-12:15 MG 8 : Protein Synthesis and Mutations
1:00-2:30 Review of Physiology Exam II (Optional)
Tues
July 29
Weds
July 30
Thurs
July 31
Friday
Aug 1
8:00-10:00 MG 9 : Cell Cycle & DNA Replication Fundamentals
10:15-12:15 MG 10 : DNA Replication, Inhibitors and DNA Damage
1:00-2:30 A&H Practice Practical (MDL 2)
8:00-10:00 CP 24 : Modifying Gas Exchange
10:15-12:15 CP 25 : Cardiovascular Responses to Drugs 1
8:00-10:00 CP 26 : Cardiovascular Responses to Drugs 2
10:15-12:15 MG 11 : DNA Repair, Repair Deficiencies and Cancer
1:00-2:30 A&H Comprehensive Practical Exam (MDL 2)
8:00-9:00 MG 12A : Traditional and Targeted Chemotherapeutics
9:00-10:00 MB 12B : TBL-2: Molecular Biology
10:15-12:15 Review for Molecular Genetics Exam
S. Schneid
S. Schneid
S. Schneid/
P.Kingston
A. Apperson
P. Kingston
P. Kingston
A. Apperson
P. Kingston
A. Apperson
P. Kingston
S. Schneid
A. Apperson
A. Apperson
A. Apperson
S. Schneid
A. Apperson
A. Apperson
A. Apperson
P. Kingston
A. Apperson
P. Kingston
A. Apperson
P. Kingston
A. Apperson
P. Kingston
A. Apperson/
P.Kingston
P. Kingston
K. Brandl
A. Apperson/
P.Kingston
A. Apperson
A. Apperson
P. Kingston
P. Kingston
S. Schneid
S. Schneid
A. Apperson
P. Kingston
A. Apperson
A. Apperson
A. Apperson
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Monday
Aug 4
*note time changes
Tues
Aug 5
Weds
Aug 6
Thurs
Aug 7
Friday
Aug 8
Week 7
8:00-10: 10 MOLECULAR GENETICS EXAM A. Apperson
10: 30 -12: 30 CP 27 : Clinical Correlation: Heart Disease (Skaggs Auditorium) - D. Blanchard
1:00-2:30 Review of Molecular Genetics Exam (Optional) A. Apperson
8:00-10:00 CP 28 : Coronary Blood Flow
10:15-12:15 CP 29 : Cardiopulmonary Responses to Exercise
8:00-10:00 CP 30 : Analyzing Clinical Scenarios
10:15-12:15 Study Time
8:00-10:00 Study Time
10:15-12:15 Review for Physiology Final (Optional)
9:00-12:00
1:00-3:00
PHYSIOLOGY FINAL
Review of Physiology Final (Optional)
S. Schneid
A. Apperson
P. Kingston
S. Schneid/
P.Kingston/
A. Apperson
S. Schneid
S. Schneid/
P.Kingston/
A. Apperson
By appointment
By appointment
Remediation meetings
Week 8
By appointment
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