ALCOHOLISM LECTURE OUTLINE • Historical perspective • Diagnostic issues • Prevalence and Canadian consumption patterns • Effects • Etiology • Treatment ALCOHOLISM Historical perspective • alcohol and drug use has been around for centuries • N. America – impacts on aboriginal people • Prohibition in the 1920s • 1950s – introduction of major and minor tranquilizers • 1960s – recreational use of drugs • today – proliferation of prescription drugs ALCOHOLISM Diagnostic issues • Substance intoxication • Substance abuse • Substance dependence (addiction) – physiological dependence, tolerance, withdrawal; psychological dependence, habituation • Polysubstance abuse – synergistic effects ALCOHOLISM Prevalence Ontario Health Supplement • highest rates for males ages 15-24 – 12% of men, 3% of women have problems with substance abuse • increase in consumption from 1971 – 1987, then sharp drop, especially use of spirits • native youth – similar rates of alcohol abuse, but higher rates of use of cigarettes and other drugs (Gfellner & Hundleby, 1995) ALCOHOLISM Effects • short-term – biphasic effect (euphoria, then acts as depressant) • long-term – vitamin B deficiency, liver disease, appetite suppression • fetal alcohol syndrome (FAS) • social costs of alchoholism – health care, lost productivity, motor vehicle accidents, suicide • alcohol used by people with other mental disorders – self-medication ALCOHOLISM Etiology • genetics – MZ twins have concordance rates of 56% compared with 29% for DZ twins • some suggestion that a gene on chromosome 11 is involved, related to dopamine reception • type I alcoholism – onset of drinking in 20-30 age range, prone to liver disease, • type II alcoholism – higher heritability component for sons, earlier onset of drinking, antisocial problems, but not as prone to medical problems ALCOHOLISM Etiology • Biological markers – sons of fathers with alcoholism have higher than normal rates of fast beta wave activity, also increased heart rate following alcohol intake, suggesting that alcohol is a reward; low MAO activity, particularly those with type II • low levels of serotonin – impulsivity, aggression, antisocial behaviour (type II) • Psychological factors – Freud – oral fixation, dependency, enablers ALCOHOLISM Etiology • Primary alcoholism – men who are aggressive, bold, hedonistic • Secondary alcoholism – use alcohol to cope with anxiety and depression, punishment avoidance, tension reduction • Alcohol expectancy theory – belief that alcohol will lead to positive outcomes such as social skills, tension reduction, sexual performance • Sociocultural and family factors ALCOHOLISM Treatment • Minnesota model • Drug treatment – naltrexone and antabuse • Alcoholics Anonymous (AA) • Behavioural treatment • Relapse prevention • Marital and family therapy • Controlled drinking controversy ALCOHOLISM SUMMARY • Biopsychosocial model provides the best account for alcoholism • A variety of approaches to treatment – success heavily dependent on person’s willingness to overcome problem drinking • Problem of relapse