Make V-line face Best solution for making little face Make well-balanced face line Using the injectable for treatment of edema, lymph circulation, lipolysis. Using Meso-toxin for a square jaw. Using a lifting thread for a face line. Preservative-free production Sterile filter manufacturing High-pressure sterilization products Cheek line Double chin Drooped earlobe Nasolabial folds The lasted trend in meso-treatment to diffidence locations with very simple treatment. Medical uses : The seed extract standardized to around 20 percent aescin (escin) is used for its venotonic effect, vascular protection, antiinflammatory and free radical scavenging properties. Primary indication is chronic venous insufficiency. A recent Cochrane Review found the evidence suggests that Horse Chestnut Seed Extract is an efficacious and safe short-term treatment for chronic venous insufficiency. Aescin reduces fluid leaks to surrounding tissue by reducing both the number and size of membrane pores in the veins β-Aescin (main component) Every part of the plant except the seed contains nicotine, but the concentration is related to different factors such as species, type of land, culture and weather conditions. The concentration of nicotine increases with the age of the plant. Tobacco leaves contain 2 to 8% nicotine combined as malate or citrate. The distribution of the nicotine in the mature plant is widely variable: 64% of the total nicotine exists in the leaves, 18% in the stem, 13% in the root, and 5% in the flowers. Tobacco contains the following phytochemicals: nicotine, anabasine (an alkaloid similar to the nicotine but less active), glucosides (tabacinine, tabacine), 2,3,6-trimethyl-1,4-naphthoquinone, 2methylquinone, 2-napthylamine, propionic acid, anatalline, anthalin, anethole, acrolein, anatabine, cembrene, choline, nicotelline, nicotianine, and pyrene. nicotine Pulsatilla koreana, the Korean pasque flower (Korean Hal-me-kot, 할미꽃), is one species of the genus Pulsatilla. P. koreana is a hairy, tufted, perennial herb. It is a native perennial plant growing in Korea and used as a traditional Korean herbal medicine. Pulsatilla koreana is a traditional Korean herbal medicine. The rhizomes of. P. koreana have been used as a traditional Korean medicine for amoebic dysentery, malaria, epistaxis, leucorrhoea, scrofula, internal hemorrhoids and also as a contraceptive. The root is antiinflammatory and antiparasitic. It contains several medically active constituents including saponins and anemonin. There are 17 saponins, two of which, derived from the saponin hederagenin, were found to be potent anti-tumor agents. Anemonin has been shown to have both cardiotoxic and cardiotonic properties. saponin Adenosine (ADO) is a purine nucleoside comprising a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine plays an important role in biochemical processes, such as energy transfer — as adenosine triphosphate (ATP) and adenosine diphosphate (ADP) — as well as in signal transduction as cyclic adenosine monophosphate (cAMP). It is also a neuromodulator, believed to play a role in promoting sleep and suppressing arousal. Adenosine also plays a role in regulation of blood flow to various organs through vasodilation. Adenosine is an endogenous purine nucleoside that modulates many physiological processes. Cellular signaling by adenosine occurs through four known adenosine receptor subtypes (A1, A2A, A2B, and A3). Extracellular adenosine concentrations from normal cells are approximately 300 nM; however, in response to cellular damage (e.g. in inflammatory or ischemic tissue), these concentrations are quickly elevated (600–1,200 nM). Thus, in regard to stress or injury, the function of adenosine is primarily that of cytoprotection preventing tissue damage during instances of hypoxia, ischemia, and seizure activity. Activation of A2A receptors produces a constellation of responses that in general can be classified as anti-inflammatory. Nicotinamide has demonstrated anti-inflammatory actions that may be of benefit to patients with inflammatory skin conditions.[4] These conditions include acne vulgaris, and the compound can suppress antigen-induced, lymphocytic transformation and inhibit 3',5'-cyclic-AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne. NicAzel and Nicomide are the names of oral acne medications that include nicotinamide as their most predominant ingredient, based on this area of research. Nicotinamide is also found as part of a new adjunct supplement combination called, AzerizinTM. According to the makers of Azerizin, this adjunct is part of their prescription dietary supplement product, which they claim helps manage inflammatory skin conditions. Nicotinamide is also used topically as a 4% or 5% gel or cream - as effective as topical 1% clindamycin (8-week double-blind trial) performed at the New York University College of Medicine.[5] Unlike topical Erythromycin or Clindamycin it does not precipitate bacterial resistance in treating inflammatory acne. Nicotinamide acne treatment is also available as Nicotinamide pads and cream. Nicotinamide is also reported to be an effective skin whitener in topical application. Indication Quantity per Point Total quantity Initial # treatments Cheeks 0.1ml~ 2ml~3ml 1 session/week for 3 weeks 0.1 ml~ 2ml~3ml 1 session/week for 3 weeks 0.1 ml~ 4ml 1 session/week for 4 weeks double chin (cellulite) Arms, love line Before & After after two weeks Before & After after two weeks Before & After after two weeks Before & After after two weeks