Pharmacology PH 148J

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Brand: Prilosec/Zegerid
Generic: omeprazole
(oh-mep-rah-zole)
Classification: proton pump inhibitor
FDA approved in 1989
Indications:
Duodenal Ulcers; Heartburn;
GERD (Gastric Esophageal Reflux Disease;
Unlabeled uses:
Posterior Laryngitis;
Dosage forms:
Prilosec/Omeprazole DR Capsules
10mg, 20mg, 40mg
Prilosec OTC DR Tablets 20mg
Zegerid powder for oral suspension
20mg, 40mg in 30 unit-dose packages
Brand: Nexium
Generic: esomeprazole (es-oh-mep-rah-zole)
Classification: proton pump inhibitor
FDA approved in 2001
Indications:
GERD; Erosive Esophagitis; Risk reduction of
NSAID induced gastric ulcers; h. pylori infection;
Dosage forms:
Nexium (Brand Only) DR Capsules
20mg, 40mg
Nexium I.V. Powder for Injection
Freeze Dried 20mg, 40mg
Warning Labels:
Brand: Prevacid
Generic: lansoprazole (lan-soh-prah-zole)
Classification: proton pump inhibitor
FDA Approved in 1995
Indications:
Duodenal Ulcers; Erosive Esophagitis;
(GERD); Gastric Ulcers;
Unlabeled uses:
Treatment of GERD in infants and children;
Dosage forms:
Prevacid (Brand Only) DR Capsules 15mg, 30mg
Prevacid DR Granules for oral suspension 15mg
Prevacid DR Oral Desintigrating Tablets 15mg
Prevacid IV Powder for Injection 30mg/vial
Brand: Aciphex
Generic: rabeprazole (ray-bep-rah-zole)
Classification: proton pump inhibitor
FDA approved in 1999
Indications:
Duodenal Ulcers; Erosive Ulcerative Esophagitis;
GERD; h. pylori eradication; Hyper secretory conditions;
Unlabeled uses:
Treatment of Gastric Ulcers;
Dosage forms:
Aciphex (Brand Only)
DR Tablets 20mg
Brand: Protonix
Generic: pantoprazole (pan-toh-prah-zole)
Classification: proton pump inhibitor
FDA approved in 2000
Indications:
Erosive Esophagitis; GERD;
Unlabeled uses:
Treatment of Duodenal Ulcers;
Dosage forms:
Protonix Delayed Release Tablets
20mg, 40mg
Protonix I.V. Powder for Injection
40mg/vial
Brand: Tagamet
Generic: cimetidine (sih-met-ih-dine)
Classification: histamine H2 antagonist
FDA approved in 1977
Indications:
Duodenal Ulcers; Benign Gastric Ulcers;
GERD; Upper GI Bleeding; Heartburn;
Dosage forms:
Tagamet/Cimetidine Tablets
300mg, 400mg, 800mg;
Cimetidine Oral Solution 300mg/5ml;
Cimetidine For Injection150mg/ml;
OTC Tagament HB 200mg
Brand: Zantac
Generic: ranitidine (ran-ih-tah-dine)
Classification: histamine H2 antagonist
FDA approved in 1983
Indications:
Duodenal Ulcer; GERD; Erosive Esophagitis;
Heartburn;
Dosage forms:
Ranitidine/Zantac 75 (OTC) 75mg
Ranitidine/Zantac 150 (OTC) 150mg
Ranitidine/Zantac (Rx) Tablets 150mg, 300mg
Zantac EFFERdose Tablets 25mg, 150mg
Ranitidine/Zantac Syrup 15mg/ml
Ranitidine/Zantac Injection 1mg/ml, 25mg/ml
Brand: Axid
Generic: nizatidine (nih-zah-tih-dine)
Classification: histamine H2 antagonist
FDA approved in 1988
Indications:
Duodenal Ulcers; Benign Gastric Ulcers;
GERD; Heartburn;
Dosage forms:
Axid AR (OTC) 75mg Tablets
Axid Pulvules/Nizatidine Capsules
150mg, 300mg
Axid Oral Solution 15mg/ml
Warning Labels:
Avoid Antacids;
Brand: Pepcid
Generic: famotidine (fam-oh-ti-dine)
Classification: histamine H2 antagonist
FDA approved in 1986
Indications:
Duodenal Ulcer; GERD; Heartburn;
Dosage forms:
Pepcid AC/Famotidine (OTC) 10mg
Pepcid AC Maximum Strength 20mg
Pepcid/Famotidine (Rx) 20mg, 40mg;
Pepcid AC Gelcaps/Chewtabs (OTC) 10mg;
Pepcid RPD (Rx) Oral Disintegrating Tablets
20mg, 40mg
Pepcid/Famotidine (Rx) Injection
10mg/ml, 20mg/50ml;
Brand: Cytotec
Generic: misoprostol (mis-oh-pro-stole)
Classification: prostaglandins
FDA approved in 1988
Indications:
Treatment for NSAID induced Ulcers;
Unlabeled uses:
Cervical ripening and labor induction;
Termination of pregnancy;
Postpartum hemmorrhage;
Idiopathic Constipation;
Dosage forms:
Cytotec/Misoprostol Tablets 100mcg, 200mcg;
Warning Labels:
Brand: Bentyl/Byclomine/Di-Spaz
Generic: dicyclomine (di-cy-cloh-meen)
Classification: antispasmodic
Indications:
Treatment of Irritable Bowel Syndrome;
Dosage forms:
Bentyl/Dicyclomine/Byclomine/Di-Spaz
Capsules 10mg, 20mg
Tablets 20mg;
Bentyl/Dicyclomine Syrup 10mg/5ml
Bentyl/Dicyclomine/Dibent/Dilomine/Di-Spaz
Or-Tyl Injection 10mg/ml
Warning Labels:
AACD;
Take 30 min prior to meals;
Brand: Levsin
Generic: hyoscyamine sulfate
(hi-oh-sigh-ah-meen-sul-fate)
Classification: antispasmodic
Indications:
To aid in the control of gastric secretions;
Adjunctive therapy to irritable colon, spastic
Colon, peptic ulcers;
Dosage forms:
Levsin/Hyoscyamine Sulfate Tablets
0.125mg, 0.15mg
Levsin/Hyoscyamine Sulfate XR Tablets
0.375mg
Levsin/Hyoscyamine Sulfate SL Tablets
0.125mg
Levsin Injection 0.5mg/ml
Levsin Elixer 0.125mg/5ml
Levsin XR Capsules 0.375mg
Brand: Asacol
Generic: mesalamine
(meh-sah-lah-meen)
Classification: anti-inflammatory
Indications:
Chronic Inflammatory Bowel Disease;
Treatment of Ulcerative Colitis;
Dosage forms:
Asacol Delayed Release Tablets 400mg
Pentasa Controlled Release Capsules 250mg, 500mg
Canasa/FIV/ASA Suppositories 500mg, 1000mg
Mesalamine/Rowasa Enema 4g/60ml
Warning Labels:
Swallow tablets whole; Shake enema well before use;
Remove foil wrapper from suppository and insert;
Brand: Remicade
Generic: infliximab (in-flix-ih-mab)
Classification: treatment for Crohns disease
FDA approved in 1998
Indications:
Moderate to severe Crohn’s Disease;
Rheumatoid Arthritis (RA);
Unlabeled uses:
Treatment of Plaque Psoriasis or Ulcerative
Colitis;
Dosage forms:
Remicade (Brand Only) Powder for Injection
100mg/20ml single use vial;
Warning Labels:
AACD;
Brand: Miralax
Generic: polyethylene glycol
(pah-lee-eth-ah-leen-gly-call)
Classification: bowel evacuant
Indications:
Treatment of constipation
Dosage forms:
Glycolax 255g, 527g granuals to mix
With 8 oz of water.
Brand: Colace/DOSS
Generic: docusate sodium
(dock-you-sayt-soh-de-um)
Classification: stool softener
Indications:
Stool softener; Treatment of constipation;
Dosage forms:
Colace/DOS/Various Brands
Tablets 100mg;
Capsules 50mg, 100mg, 250mg
Soft Gel Capsules 50mg, 100mg, 250mg
Syrup 20mg/ml, 50mg/5ml;
Brand: Dulcolax
Generic: bisacodyl (bih-sah-co-dill)
Classification: laxative
Indications:
Treatment of constipation;
Dosage forms:
Dulcolax/Bisacodyl/Various EC Tablets 5mg
Dulcolax/Bisacodyl/Various DR Tablets 10mg
Dulcolax/Bisacodyl/Various Suppositories 10mg
Warning Labels:
Swallow EC and DR tablets whole;
Remove foil from suppositories prior to insertion;
Brand: Lomotil
Generic: diphenoxylate HCL w/Atropine sulfate
(di-fen-oxy-layt-h-c-l-with-ah-tro-peen-sul-fayt)
Classification: antidiarrheal
Indications:
Adjunctive therapy in the management of Diarrhea;
Dosage forms:
Lomotil (Brand/Generic) Tablets 2.5mg
Lomotil (Brand/Generic) Liquid 2.5mg/5ml
Warning Labels:
AACD;
May cause dry mouth;
Brand: Imodium
Generic: loperamide
(low-pear-ah-myde)
Classification: antidiarrheal
Indications:
Control and symptomatic relief of acute
Nonspecific diarrhea and chronic diarrhea;
Unlabeled uses:
Travelers Diahrrhea
Dosage forms:
Imodium A-D Caplets (OTC) 2mg;
Imodium A-D/Loperamide Capsules 2mg
Warning Labels:
Brand: Reglan
Generic: metoclopramide
(meh-toh-cloh-prah-myde)
Classification: GI stimulant
Indications:
Stimulate Gastric Emptying for radiological
Examinations; Reduction of Post-Op N&V;
Unlabeled Uses:
Improve Lactation;
Dosage forms:
Reglan/Metaclopramide Tablets 5mg, 10mg;
Reglan/Metaclopramide Syrup 5mg/5ml;
Reglan/Metaclopramide Injection 5mg/ml;
Warning Labels:
AACD; Take 30 min prior to meals;
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