Crick Supervisors for Crick-BRC CRTF Call January 2016 Name (linked to homepage) Dimitrios Anastasiou email Research Group Name <Dimitrios.Anastasiou@crick.ac.uk> Cancer metabolism Paul Bates <Paul.Bates@crick.ac.uk> Biomolecular Modelling Axel Behrens Kate Bishop Mike Blackman <Axel.Behrens@crick.ac.uk> <Kate.Bishop@crick.ac.uk> <Mike.Blackman@crick.ac.uk> Dominique Bonnet <Dominique.Bonnet@crick.ac.uk> Simon Boulton James Briscoe Denis Burdakov Dinis Calado Luiz Pedro Carvalho <Simon.Boulton@crick.ac.uk> <James.Briscoe@crick.ac.uk> <Denis.Burdakov@crick.ac.uk> <Dinis.Calado@crick.ac.uk> <Luiz.Carvalho@crick.ac.uk> Peter Cherepanov Alessandro Costa <Peter.Cherepanov@crick.ac.uk> <Alessandro.Costa@crick.ac.uk> John Diffley <John.Diffley@crick.ac.uk> Adult stem cell function in disease Infection and replication of retroviruses Proteases in host cell exit and invasion by the malaria parasite Human normal and malignant haematopoietic stem cells and their microenvironment The DNA damage response Neural tube development Neural circuits, instincts, sleep and appetite Immune cell development and cancer Mycobacterium tuberculosis systems and chemical biology Chromatin structure and mobile DNA Architecture and dynamics of macromolecular machines Chromosome replication Julian Downward Eva Frickel <Julian.Downward@crick.ac.uk> <Eva.Frickel@crick.ac.uk> Steve Gamblin <steve.gamblin@crick.ac.uk> Mike Gilchrist Nathan Goehring Alex Gould Francois Guillemot Maximiliano Gutierrez <Mike.Gilchrist@crick.ac.uk> <Nate.Goehring@crick.ac.uk> <Alex.Gould@crick.ac.uk> <Francois.Guillemot@crick.ac.uk> <Maximiliano.Gutierrez@crick.ac.uk> Adrian Hayday Caroline Hill <Adrian.Hayday@crick.ac.uk> <Caroline.Hill@crick.ac.uk> Tony Holder George Kassiotis <Tony.Holder@crick.ac.uk> <George.Kassiotis@crick.ac.uk> Jean Langhorne <Jean.Langhorne@crick.ac.uk> Steve Ley <Steve.Ley@crick.ac.uk> Vivian Li <Vivian.Li@crick.ac.uk> Robin Lovell-Badge Nicholas Luscombe Ilaria Malanchi <Robin.Lovell-Badge@crick.ac.uk> <nicholas.luscombe@crick.ac.uk> <Ilaria.Malanchi@crick.ac.uk> Neil McDonald <Neil.McDonald@crick.ac.uk> Tim Mohun Justin Molloy <Tim.Mohun@crick.ac.uk> <Justin.Molloy@crick.ac.uk> Oncogenic Ras signalling in transformation A new perspective on anti-Toxoplasma gondii immunity Structural biology of influenza, energy metabolism and cancer epigenetics Gene regulatory networks in early development Systems biology of cell polarity networks Regulation of growth and metabolism Generation of cell diversity in the brain Cell biology of host-pathogen interactions in tuberculosis T cells in tissue stress-surveillance and cancer TGF-β superfamily signalling in development and cancer Malaria parasites and red blood cells Antiviral immunity Immunology and immunopathogenesis of malaria infections Regulation of inflammation by MAP kinases and NF-kB Wnt signalling pathway, intestinal stem cells and cancer Sex, stem cells and decisions of cell fate Bioinformatics and computational biology Tumour-stroma interactions in cancer development Structural biology of growth factor signalling and cell polarity Heart formation in vertebrates Single molecule studies of cell motility and cell signalling Mechanisms of lineage specification in human embryos and stem cells Regulation of cell cycle, cell form and cell growth Regulation of the immune response in infectious disease Patterning embryos with oscillations Development of the nervous system Neutrophils in immune defence and disease Kathy Niakan <Kathy.Niakan@crick.ac.uk> Paul Nurse Anne O’Garra <paul.nurse@crick.ac.uk> <Anne.OGarra@crick.ac.uk> Andrew Oates Vassilis Pachnis Venizelos Papayannopoulos Peter Parker Markus Ralser Caetano Reis e Sousa Katrin Rittinger <Andrew.Oates@crick.ac.uk> <Vassilis.Pachnis@crick.ac.uk> <veni.p@crick.ac.uk> Peter Rosenthal Erik Sahai Guillaume Salbreux Iris Salecker Paola Scaffidi Andreas Schaefer Martin Singleton Steve Smerdon <Peter.Rosenthal@crick.ac.uk> <Erik.Sahai@crick.ac.uk> <Guillaume.Salbreux@crick.ac.uk> <Iris.Salecker@crick.ac.uk> <Paola.Scaffidi@crick.ac.uk> <Andreas.Schaefer@crick.ac.uk> <Martin.Singleton@crick.ac.uk> <Steve.Smerdon@crick.ac.uk> Jim Smith Gitta Stockinger <jim.smith@crick.ac.uk> <BriGitta.Stockinger@crick.ac.uk> Jonathan Stoye Thomas Surrey <Jonathan.Stoye@crick.ac.uk> <Thomas.Surrey@crick.ac.uk> Jesper Svejstrup Charles Swanton Nic Tapon <Jesper.Svejstrup@crick.ac.uk> <Charles.Swanton@crick.ac.uk> <Nic.Tapon@crick.ac.uk> PKC signalling in cell proliferation and cancer Dynamics and evolution of metabolic networks Dendritic cells and innate immunity Structural biology of innate and adaptive immune signalling Electron cryomicroscopy of viruses and cells Cell Biology of the tumour microenvironment Theoretical physics of biology Visual circuit assembly in Drosophila Cancer epigenetics Neurophysiology of behaviour Structural biology of chromosome segregation Structural biology of the cell-cycle and DNA damage response The molecular basis of mesoderm formation Maintenance and regulation of peripheral immune responses Retrovirus–host interactions Synthetic and systems biochemistry of the microtubule cytoskeleton Transcription and the repair of DNA damage Cancer evolution and genome instability Control of tissue growth and architecture Ian Taylor <Ian.Taylor@crick.ac.uk> Macromolecular assemblies Willie Taylor Barry Thompson Peter Thorpe <William.Taylor@crick.ac.uk> <Barry.Thompson@crick.ac.uk> <Peter.Thorpe@crick.ac.uk> Pavel Tolar Sharon Tooze Moritz Treeck Richard Treisman James Turner Victor Tybulewicz <Pavel.Tolar@crick.ac.uk> <Sharon.Tooze@crick.ac.uk> <Moritz.Treeck@crick.ac.uk> <richard.treisman@crick.ac.uk> <James.Turner@crick.ac.uk> <Victor.T@crick.ac.uk> Frank Uhlmann Sila Konur Ultanir <frank.uhlmann@crick.ac.uk> <Sila.Ultanir@crick.ac.uk> Peter Van Loo Folkert van Werven Jean-Paul Vincent Andreas Wack Michael Way <peter.vanloo@crick.ac.uk> <Folkert.vanWerven@crick.ac.uk> <JP.Vincent@crick.ac.uk> <Andreas.Wack@crick.ac.uk> <Michael.Way@crick.ac.uk> Protein structure analysis and design Cell polarity and tissue morphogenesis Systems microscopy studies of cell division and cell fate determination Activation of immune receptors Molecular cell biology of autophagy Parasite host-cell interactions Transcriptional responses to Ras and Rho signalling Sex chromosomes in development and disease Signal transduction from the antigen receptors of B and T cells Chromosome Segregation Kinase signaling pathways in neuronal dendrite development Cancer genomics Cell fate and gene regulation Patterning and homeostatis in developing epithelia Immune response to influenza Cellular signalling and cytoskeletal function Martin Webb <Martin.Webb@crick.ac.uk> The molecular mechanisms of motor proteins <Peter.Parker@crick.ac.uk> <Markus.Ralser@crick.ac.uk> <Caetano@crick.ac.uk> <Katrin.Rittinger@crick.ac.uk> Stephen West David Wilkinson <Stephen.West@crick.ac.uk> <David.Wilkinson@crick.ac.uk> Robert J Wilkinson <Robert.Wilkinson@crick.ac.uk> Hasan Yardimci Douglas Young Mariia Yuneva <Hasan.Yardimci@crick.ac.uk> <Douglas.Young@crick.ac.uk> <Mariia.Yuneva@crick.ac.uk> DNA recombination, repair and cancer Regulation of boundary formation and neurogenesis Understanding and intervening in tuberculosis and HIV associated tuberculosis Single molecule imaging of DNA replication Mycobacterium tuberculosis and the host response Oncogenes and tumour metabolism