The ABC’s of DNR Gary Winzelberg, MD MPH Division of Geriatric Medicine Palliative Care Program 01/05/10 Questions • • • • Challenging DNR discussions Easy discussions Observations of attendings, fellows Attending feedback Internship Memory/Flashback • • • • • • Chronically ill (elderly) patient admitted with… “Is Mr. Smith DNR?” “I don’t know.” “He should be.” Pressure to get DNR order Discomfort when caring for “full code” chronically ill patients – What are we doing? • DNR as symbol beyond actual order Objectives • Historical context • Data • CPR outcomes • Patient preferences • Communication strategies – Approach to advance care planning on admission DNR Order Pendulum at UNC • 2002 – DNR order required attending approval – Overnight calls to verbally approve DNR orders • 2009 – DNR orders written without any attending supervision – Consider code status discussions as a procedure Cardiopulmonary Resuscitation • Medical response to cardiac arrest • • • • Defibrillation Chest compressions Medications Intubation “Closed-Chest Cardiac Massage” • JAMA article, 1960 • Cardiac resuscitation limited by need for open thoracotomy and direct cardiac massage • Method of external transthoracic cardiac massage • 70% permanent survival rate, 20 patients • “Anyone, anywhere, can now initiate cardiac resucitative procedures. All that is needed are two hands.” CPR As Default Policy • 1965 reclassification as universal emergency procedure that anyone could perform • Initiate CPR regardless of medical condition • Principle that doctors should try to prevent death “Orders Not To Resuscitate” • 1976 NEJM article • Concern: inappropriate to apply technology to the fullest extent in all cases and without limitation • Increased awareness of patient rights CPR vs. DNR: Hospital Culture Tension • “Code status” dominant preoccupation of doctors & nurses when death seems near • Doctors often don’t want to talk about code status to sick patients or their families (& frequently don’t) • Patients & families don’t realize that they must request DNR • Doctors feel pressure to inform patients, families of their choice; families feel coerced, guilty, life or death responsibility Sharon Kaufman, …And A Time To Die “Should We Restart Your Heart?” • • • • • • • ER, Chicago Hope, Rescue 911 episodes (’94, ’95) Majority of cardiac arrests caused by trauma 28% arrests due to cardiac causes 10% elderly 77% short-term survival 37% survival to discharge after CPR CPR misrepresentations may lead patients to generalize impressions to CPR in real life Diem SJ, NEJM 1996 TV vs. Reality • • • • • Event: trauma Age: younger adults Rhythm: VF/VT Short-term survival: 75% Long-term survival: presumed good • Function: normal • • • • • • Event: chronic illness Age: older adults (avg 70 yo) Rhythm: ½ VF, ½ asystole Hospital d/c survival: 18% Long-term survival: poor Function: impaired Out-of-Hospital CPR Outcomes (King County, WA) Age < 80 year old 81-90 > 90 VF & VT < 80 year old 81-90 > 90 Survival to Hospital Discharge 19.4% 9.4% 4.4% 36% 24% 17% Kim C, Arch Intern Med 2000 Effect of Age on Surviving CPR • Weak association with decreased survival to hospital discharge • OR 0.92 (0.85-0.99) for every decade • Fewer octogenarians have VF/VT Kim C, Arch Intern Med 2000 In-Hospital CPR Outcomes (Ehlenbach WJ, NEJM 2009) • • • • 1992-05, >65 yo, 433,985 attempts 18.3% survived to hospital discharge No increase in survival during study period Survival lower among: men 17.5% vs women 19.2%, older age (65-69 = 22% vs > 90 = 12%, coexisting illness (Deyo score >3 = 16% vs 19% if zero), admitted from SNF 11.5% vs 18.5% • Survival higher in MI (20.4% vs 17.8%) & CHF (20.4% vs 17.1%) In-Hospital CPR Outcomes (2) • A-A with lower survival (14.3) compared with whites (19.2%) – A-A more likely to receive care in hospitals with lower survival rates • Proportion of patients discharged home decreased over time (60% to 35%) • Proportion of patients discharged to SNF increased over time (15% to > 20%) • No data on functional outcomes CPR Preference & Survival Probability • 371 patients, mean age 77, 84% white Survival Rate (%) Opting for CPR (%) 1 10 5-10 10 20-40 22 50 25 > 60 8 Didn’t want CPR 25 Murphy DJ, NEJM 1994 Survival Probability on Patient Preferences Chronic Illness Patients’ estimate = 15% + 16 CPR preference before learning probability = 11% CPR preference after learning probability = 5% Murphy DJ, NEJM 1994 Functional Outcome After Hospital CPR • 162 survivors of in-hospital CPR • 56%: same or improved function • 44%: worse function at 2 months • Mean ADL decline: 3.9 (0-7 dependencies) • Eating, continence, toileting, transferring, bathing, dressing, walking • Age > 75 vs. < 55: OR 5.25 worse functional status Fitzgerald JD, Arch Intern Med 1997 Factors associated with DNR Orders • Patient preference • 52% with DNR preference had written order • Probability of surviving for 2 months • Age • Orders written more quickly for patients > 75 independent of prognosis Hakim RB, Ann Intern Med 1996 Code-Status Discussion Barriers • • • • • • Qualitative study of family physicians & residents Personal discomfort with confronting mortality Fear of damaging the doctor-patient relationship Fear of harming patient by discussing death Limited time to establish trust Difficulty in managing complex family dynamics Calam B, CMAJ 2000 How Do Residents Discuss CPR? • • • • • • 1992 UCSF study, audiotaped inpatient discussions Median discussion length 10 minutes (2.5 – 36 mins) Physician spoke 73% of time Median time patients spoke: 2 min 30 sec 13%: likelihood of CPR survival 10%: discussion of patient goals, values Tulsky JA, J Gen Intern Med 1995 Resident Approaches to Advance Care Planning on Admission Smith AK. Arch Intern Med 2006 • • • • • • • 2005 survey of Duke, Brigham medicine residents 70% established CPR preference 34% health care proxy, 36% advance directive 32% discussed end of life care goals & values 89% observed model of advance care planning 37% received feedback 47% -- goals/values important to discuss on admission – Barriers: time, know patient better, documentation pressures Overall Communication Approach • Establish preferred decision-makers, directives • Identify patients with clear CPR attempt preferences • Place code status in context • Treatment decisions • Patients’ goals, values • Patients’ medical condition • Support patients, families with end-of-life decisionmaking • Make recommendations • Give permission to choose approach other than diseaseoriented focus Patients With DNR Directive • Attempt to confirm preference • Immunity from liability for complying with a directive • Opportunity to discuss care goals, treatment preferences • Care goals: longevity, function, comfort • Assure patient, family that DNR does not mean “do not treat” DNR Effects on M.D. Decision-Making • 72 yo male with advanced multiple myeloma, dementia, admitted with delirium Treatment Blood cxs Central line Blood transfusion Dialysis ICU transfer Intubation *p < 0.05 DNR absent 83% 80% 87% 20% 34% 35% DNR present 82% 68%* 75%* 9%* 16%* 5%* Beach MC, J Am Geriatr Soc 2002 Patients Without DNR Directive • Avoid… • Should we try to restart your heart? • Should we shock you, press on your chest? • Should we not do anything? • “Short, Tall, Grande” discussions • Communication hygiene • Sit down • Privacy “Short” DNR Discussion (1) • Who would the patient want to communicate with physicians, make decisions if incapacitated? • Has the patient discussed care preferences? • Advance directive? Why? • What thoughts have you had about how you’d like to be treated if your condition worsened, if you became much sicker than you are now? • State your goal: treat the patient as consistent with his preferences/values as possible “Short” DNR Discussion (2) • Framing, reflecting information content from patient/family – demonstrate that you’ve listened • There’s an intervention that can be attempted if your so heart stops…From what you’ve said it sounds as if… • Share likely outcome: There’s a low/extremely low chance that you would survive and regain your current level of function • We would focus on making sure that you’re comfortable • Alleviate caregiver guilt “Tall” DNR Discussion • Ask about the patient’s story (establish trust) • How do you think you’ve been doing? • Elicit goals • What things are most important to you in your day-to-day life? • What are your priorities? Longevity, function, comfort • Caution re: quality of life discussion • Focusing on your function, comfort would mean…translate information into specific treatment recommendations (place DNR in context of care plan) Communication Documentation • • • • Use advance care planning template in Webcis Central location for data (phone numbers) Describes content of communication Assists with continuity of discussions among physicians Key Communication Elements • Trust • Encourage patients, families to talk • Demonstrate respect • Do not force decisions • Uncertainty • Make recommendations • Allow patients, families to reject recommendations • Affect • Hope • Focus on the positive Tulsky JA, JAMA 2005 Summary • • • • CPR – DNR tension for hospitalized patients Outcomes poor for chronically ill patients Age: weak predictor of outcome Communication essential to understanding patient, family preferences • DNR considered in context of other treatment decisions, patients’ goals References 1. 2. 3. 4. Quill TE. Initiating End-of-Life Discussions With Seriously Ill Patients. JAMA 2000 Tulsky JA. Beyond Advance Directives: Importance of Communication Skills at the End of Life. JAMA 2005 Winzelberg GS, Hanson LC, Tulsky JA. Beyond Autonomy: Diversifying End-of-Life Decision-Making To Serve Patients and Families. J Am Geriatr Soc 2005 Ann Intern Med communication articles