In everyday life, we attempt to achieve as much speed as possible. Stairs V.S Elevator/ Lift Hand Wash V.S Washing Machine Knife V.S Blender Things that speed things up Chemical Reactions A B X C Y D Z So what are those that speed up the reaction called? Catalyst Definition: A catalyst is a substance which can alter or speed up a chemical reaction, without itself being chemically changed at the end of the reaction. Breakdown of Potassium Chlorate (VII) 2 KCIO3 Potassium chlorate (VII) 2 KCIO3 Potassium chlorate (VII) 2 KCI heated to more than 400 ºC CATALYST Manganese (IV) oxide Gentle heating Potassium chloride 2 KCI Potassium chloride 3 O2 Oxygen 3 O2 Oxygen Without manganese (IV) oxide With manganese (IV) oxide Temperature Without manganese (IV) oxide With manganese (IV) oxide Rate of oxygen production Manganese (IV) oxide is a catalyst Catalysts Inorganic Catalysts E.g. manganese (IV) oxide Organic / Biological Catalysts So what are organic/ biological catalysts? Enzymes What are Enzymes • Biological catalysts • Made in the cytoplasm under instruction from genes which are located on the chromosomes in the nucleus. • Made of Protein What are Enzymes Definition: Enzymes are biological catalysts made of protein which speed up the rate of chemical reactions without themselves being changed at the end of the reactions. So what chemical reactions do the enzymes catalyse? Chemical Reactions Enzyme Catalyse • Build up substances (Anabolic Reaction) Enzyme A B C • Break down substances (Catabolic Reaction) Enzyme X Y Z Chemical Reactions Enzyme Catalyse • Reversible Reactions Enzyme A B C D Build up Substances (Anabolic Reactions) Enzyme A B C Definition: Synthesis of complex molecules from simpler ones. Build up Substances (Anabolic Reactions) A Enzyme C B Examples Building Protein from Amino Acids Amino Acids Polypeptides Building glycogen from glucose. Glucose Glycogen Protein Breakdown of Substances (Catabolic Reactions) X Enzyme Y Z Definition: Breaking down of large, complex molecules into simpler ones. Breakdown of Substances (Catabolic Reactions) X Enzyme Z Y Examples Breakdown of Glucose during Respiration Breakdown of poisonous substances to harmless substances (Detoxification) Hydrogen peroxide (poisonous substance) Catalase Water + Oxygen (non-poisonous substances) Chemical Reactions Enzyme Catalyse • Reversible Reactions Enzyme A B C D Definition: Reactions that proceed in the forward or backward reaction. Chemical Reactions Enzyme Catalyse • Reversible Reactions Enzyme A B C D With so much chemical reactions and enzymes around the world, how do we differentiate them? ENZYME Now, how do we name the Enzymes? Naming of Enzymes • At first, they were named after scientists that discover them. • Enzymes are named after the substrate on which they act and with a suffix “-ase”. Naming of Enzymes • According to Type of Nutrient (Carbohydrate, Proteins, Fats) • Specific names for each type of nutrient Carbohydrate ase Naming of Enzymes Specific Carbohydrate (names ending with “ose”) Will have their ending of “ose” being replaced with “ase”. ase Maltose Substrate Name + -ase ase Cellulose Starchase Amylase ase Protein Substrate Name + -ase Naming of Enzymes Specific Protein Names will have “in” as endings. Pepsin Renin Proteins to polypeptides Polypeptides to amino acids ase Lipid Substrate Name + -ase Activity: What type of nutrient does the enzyme target? Maltase Renin Amylase Lipase Erepsin What we learn today. • Definition of Catalysts • Example of a Catalytic Reaction • Types of Catalysts • Definition of Enzymes • Reactions Catalysed by Enzymes • Naming of Enzymes