Exercise 38 Anatomy of the Digestive System Objectives • • • • • Overall function Organs of alimentary canal Accessory digestive organs General functions of organs/structures Histological structure of alimentary canal wall • Stomach and small intestine specializations • Enzymes produced • Deciduous and permanent teeth Digestive System • Provides body with nutrients, water, electrolytes essential for health • Organs ingest (take in), digest (break down), & absorb (take into bloodstream) food, and eliminate the undigested remains Alimentary Canal • Hollow tube extending from mouth to anus (gastrointestinal tract or GI tract) • Various accessory organs/glands empty into • “Disassembly Line” Alimentary Canal Histology • Mucosa (mucous membrane) Inner layer, lines lumen; secretion of enzymes, absorption of nutrients, protection LUMEN OUTER surface – Surface epithelium: simple columnar – Lamina propria: areolar connective – Muscularis mucosa: smooth muscle— local movements of mucosa – Lacteals: in villi (small fingerlike projections) of small intestine, lymphatic capillaries—transport fatty acids to bloodstream Lacteals will be in here ONE VILLUS Fig. 24-3 Alimentary Canal Histology • Submucosa (superficial to mucosa; nutrition, protection) – Blood, lymph vessels, nerve fibers – Submucosal plexus is it’s intrinsic nerve supply Fig. 24-3 Alimentary Canal Histology • Muscularis externa – Bilayer of smooth muscle: • Circular layer of muscle (deep) • Longitudinal layer of muscle (superficial) – Myenteric plexus = another intrinsic nerve plexus, controls these muscle layers major controller of GI motility Fig. 24-3 Alimentary Canal Histology • Serosa (visceral peritoneum) – Outermost tunic – Mesothelium, areolar connective tissue – Reduces friction as GI organs slide across one another and cavity’s walls, protects and anchors organs also Fig. 24-3 Alimentary Canal Organs Fig. 24-1 Alimentary Canal Organs • Oral cavity (mouth) – Labia (lips) – Hard palate (anterior roof of mouth) – Soft palate (posterior roof of mouth) – Uvula (fingerlike projection of soft palate) – Tongue (floor of oral cavity) Fig. 24-6 Pharynx Nasopharynx (behind nasal cavity) Oropharynx (behind oral cavity) Laryngopharynx (epiglottis to larynx) Fig. 24-6 Esophagus From pharynx through diaphragm to gastroesophageal sphincter at esophagus-stomach junction, controls food passage into stomach STOMACH • (left side of abdominal cavity) – Cardiac region: upper region, through which food ENTERS stomach – Fundus: superior & lateral to cardiac – Body: middle portion, inferior to fundus – Pyloric region: terminal part of stomach, continuous w/small intestine – Pyloric sphincter: between stomach & small intestine Alimentary Canal Organs • Stomach (left side of abdominal cavity) – Greater curvature: lateral, convex – Lesser curvature: medial, concave – Rugae: prominent folds in the mucosa when stomach’s empty Fig. 24-12 SMALL INTESTINE ~2m long – Duodenum: from pyloric sphincter around pancreas – Jejunum: umbilical region of abdomen – Ileum: terminal portion, joins lg intestine – Plicae circularis: like rugae, deep folds – Ileocecal valve: between small and large intestine Fig. 24-16 Fig. 24-17 LARGE INTESTINE ~1.5m long Encircles the small intestine on 3 sides – Cecum: 1st region, expanded pouch – Appendix: attached to cecum, ~3.5” long – Ascending colon: up the right side – Transverse colon: across the top – Descending colon: down the left side Fig. 24-23 LARGE INTESTINE – Sigmoid colon: S-shaped curve (behind bladder) between descending colon and – Rectum: last 6” of digestive tract – Anus: exit of the anal canal – Anal sphincter: muscle layers (2) surrounding the anus Fig. 24-23 LARGE INTESTINE –Teniae coli: 3 external longitudinal muscle bands of muscularis, shorter than rest of wall, cause it to pucker into –Haustra: small pocketlike sacs Fig. 24-23 ACCESSORY Digestive Organs • Teeth – Deciduous: appear 6 months-2.5 years; begin to lose teeth around 6 years old • 20 teeth Each SIDE of the jaw • 2, 1, 0, 2 x 2 = 20 Upper: 2I, 1C, 0 PM, 2M 2, 1, 0, 2 Lower: 2I, 1C, 0 PM, 2M SIDES of the jaw TEETH – Permanent: gradually replaces the 1st set to age 12 • 32 teeth • 2, 1, 2, 3 x 2 = 32 2, 1, 2, 3 Each SIDE of the jaw Upper: 2I, 1C, 2 PM, 3M Lower: 2I, 1C, 2 PM, 3M Permanent Teeth Central incisors For biting Lateral incisors Canines (cuspids) 1st premolars (bicuspids) 2nd premolars (bicuspids) For chewing 1st molars 2nd molars 3rd molars Fig 24-9 Fig. 24-8 Teeth • Anatomical crown: entire area of tooth covered by enamel • Clinical crown: portion of tooth visible above the gum • Root: inferior portion (base) of the tooth (below the gum) Fig. 24-8 Teeth • Enamel: “white” mineral (calcium salt) outer covering of crown • Dentin: like bone, but no cells; under enamel, it’s most of the tooth • Pulp, pulp cavity: interior chamber of the tooth—has blood vessels & nerves Fig. 24-8 SALIVARY GLANDS • Parotid glands: inferior to zyg. arch, lateral/posterior mandible • Submandibular glands: floor of mouth, along inside of mandible • Sublingual glands: floor of mouth, more anterior & under tongue Fig. 24-7 LIVER • Right, left, caudate, quadrate lobes Fig. 24-19 LIVER • Falciform ligament: divides Rt/Lt lobes Fig. 24-19 LIVER • Round ligament: thickened posterior part of falciform ligament Fig. 24-19 LIVER • Hepatic ducts: right, left—collect bile (secreted by liver) from all bile ducts of lobes, unite to form the • Common hepatic duct which leaves the liver…bile then flows to • Cystic duct which leads to the gallbladder (stores/concentrates bile) ….OR goes to the • Common bile duct which is formed by union of cystic and common hepatic ducts--empties into the duodenum (sm intest), Fig. 24-21 PANCREAS • Posterior to stomach, extends laterally off the duodenum toward the spleen • Secretes digestive enzymes and buffers via the • Pancreatic duct into the duodenum • Accessory pancreatic duct branches off the larger pancreatic duct, also empties into duodenum • Hepatopancreatic sphincter (muscle) controlling entrance of substances (from common bile duct, pancreatic duct) into duodenal ampulla Fig. 24-18 Fig. 24-21 Microscope Work • Stomach – Gastric pits: shallow depressions, open onto gastric surface; mucous cells at base of each one mitotically active—shed into chyme (acidic “soup” of stomach secretions and food) Fig. 24-13 Fig. 24-13 Microscope Work • Small intestine – Villi: fingerlike projections all over the plicae circulares One VILLUS Fig. 24-17 Microscope Work • Large intestine (no villi in colon) – Goblet cells (unicellular glands) abundant • secrete mucus to help GI motility Fig. 24-24