Towards an HIV Cure: Canadian <-> Global
Stakeholder’s Engagement Workshop
21 July 2015, 18h30 – 20h30
The International AIDS Society (IAS) Towards an HIV Cure initiative, together with our Canadian
partners CANFAR, CIHR, CanCURE and CATIE aim to encourage community contribution from
the diverse Canadian populations invested in HIV cure research.
In partnership with:
Sponsored by:
Towards an HIV Cure: Canadian <-> Global Stakeholder’s Engagement Workshop
Vancouver
Overview of the IAS Towards
an HIV Cure Initiative:
Community Efforts and
Looking Towards 2016
Towards an HIV Cure: Mission
 Facilitate scientific discussion, exchange and
collaboration to promote and accelerate
research towards a cure for HIV
 Provide leadership in advocating for increased
investment and resource optimization in HIV
cure research
 Provide clear and accurate information and
disseminate knowledge to the broader
community
Advisory
Board
Initiative Organisation
Industry Collaboration Group
Cost-effectiveness Working Group
Psychosocial Studies Working
Group
2014-2016 International Scientific
Working Group
Ethics now integrated throughout the entire initiative
Advisory Board
GOED UNTIL MONDAY 18 JULY, 14.00 CET
Launch of the Rome Statement for an HIV Cure
Scientific Discussion, Exchange & Collaboration
 Facilitate scientific
discussion, exchange and
collaboration to promote and
accelerate research towards
a cure for HIV
Global Scientific Strategy 2012
.
The International AIDS Society scientific working group on HIV
Cure. Towards an HIV cure: a global scientific strategy. Nature
Rev. Immunol. 18 Jul 2012 (doi: 10.1038/nri.3262)
Global Scientific Strategy 2016
Formation of International Scientific Working Group:
Steering Committee:
Jintanat Ananworanich, US Military HIV Research Program
Françoise Barré-Sinoussi, Institut Pasteur / Inserm
Monsef Benkirane, Institute of Human Genetics, CNRS
Steven Deeks, UCSF
Sharon Lewin, The Doherty Institute
Anna Laura Ross, ANRS / IAS
Joseph Tucker, UNC China Project
Global Scientific Strategy 2016
Identification of sub-groups
1. Molecular biology of HIV latency and shock strategies;
Chairs: Monsef Benkirane & David Margolis
2. Viral reservoirs, immunology of HIV persistence and kill strategies;
Chairs: Steven Deeks & Daniel Douek
3. Models for HIV cure or sustainable remission;
Chairs: Jintanat Ananworanich & Jeffrey Lifson
4. Gene/cell therapy;
Chairs: Paula Cannon & Daniel Kuritzkes
5. Novel biomarkers and technologies to analyse/quantify HIV
reservoirs;
Chairs: Sharon Lewin & John Mellors
6. Social sciences and health system preparedness.
Chairs: Joseph Tucker & Ying-Ru Lo
Global Scientific Strategy 2016
Timeline
Action point
February – June 2015
Circulation of subgroup draft documents,
coordinate development within sub-groups
22 June 2015
Submit developed text per sub-group to IAS
20 July 2015
2nd plenary meeting of ISWG
July – October 2015
First draft of the Global Scientific Strategy
November 2015 – January
2016
Peer review process of the Global Scientific
Strategy
Q1, 2016
Pre-final version of Global Scientific Strategy
February 2016
3rd plenary meeting of ISWG
March/April 2016
Preparation of publication
July 2016
Aim to have article published and launch of the
Global Scientific Strategy in Durban (full
recommendations prepared and final)
Working Group activities
•
Industry Collaboration Group
Enhance dialogue and interaction between public and private sectors
•
Common MTA for the use of ARVs in pre-clinical studies
•
Diagnostic companies;
•
Therapeutic vaccination/immune modulation;
•
Eradicare database.
Cost-effectiveness and Public Health Working Group
•
•
•
Opinion piece on the role of mathematical modeling and costeffectiveness analysis in the HIV cure research agenda.
Psychosocial Studies Group
•
Joined forces with the Cost-Effectiveness and Public Health WG to write
a multi-disciplinary scientific agenda for HIV cure research article.
Towards an HIV Cure Symposium
2010: HIV Reservoirs Workshop, Vienna
2012: HIV Cure Symposium, Washington DC
2013: HIV Cure Symposium, Kuala Lumpur
2014: HIV Cure Symposium, Melbourne, Australia
2015: HIV Cure Symposium, 18th-19th July,
Vancouver, Canada
Investment in HIV cure research
 Provide leadership in
advocating for increased
investment and resource
optimization in HIV cure
research
Evaluating and monitoring Investment
 Resource Tracking
Survey of global investment in HIV
cure research and development in
2012, 2013 and 2014
In collaboration with
Knowledge dissemination and information sharing
 Provide clear and accurate
information and disseminate
knowledge to the broader
community
Knowledge dissemination and information sharing
www.towardsanhivcure.org
Community Engagement
 Community Scholarships for the annual Towards an HIV Cure
Symposium
 Call for Nominations for Community Representatives to
ensure fair representation in working groups and throughout
the initiative
 HIV cure fact-sheet developed in collaboration with
community members
 Community engagement and training workshops (Washington
DC, Chennai, Melbourne, Vancouver…)
We want to hear your ideas and suggestions!
Acknowledgements
 Sponsored by:
 In Partnership with:
Acknowledgements
 Towards an HIV Cure Initiative Sponsors:
www.towardsanhivcure.org