ENZYMES ARE PROTEINS! Enzymes have names that often end in the suffix “-ase.” FOR EXAMPLE: LIPASE breaks down LIPIDS MALTASE breaks down MALTOSE PROTEASE breaks down PROTEINS ENZYMES REACT WITH ONLY ONE (1) TYPE OF MATERIAL. THIS IS CALLED A SUBSTRATE. The SUBSTRATE has a SHAPE that “FITS” together with the shape of the enzyme. THE SHAPE ON THE SURFACE OF THE ENZYME IS CALLED THE ACTIVE SITE. Notice that the SUBSTRATE has a shape that will “FIT” together with the ACTIVE SITE of the ENZYME. Together they will form an ENZYME-SUBSTRATE COMPLEX. ENZYME-SUBSTRATE COMPLEX The enzyme-substrate complex is TEMPORARY. ENZYME FUNCTION • Enzymes control the RATE of chemical reactions. That means that they SPEED UP the reaction WITHOUT BEING CHANGED! • Enzymes act as ORGANIC CATALYSTS. They lower the amount of energy needed for a reaction to occur. • Enzymes are NOT changed by the reaction so they can be used over again and again and again…. LOCK AND KEY MODEL OF ENZYME ACTION If the KEY doesn’t have a SHAPE that FITS with the LOCK, then it will not open the lock. If the ENZYME and SUBSTRATE don’t FIT together, a REACTION will NOT occur. ENZYMES DO NOT CHANGE!! After a reaction is over, the SUBSTRATE is changed, but the ENZYME remains the same. Notice that the substrate was changed at the end of the reaction. A - Enzyme B – Active Site C - Substrate D – Enzyme-Substrate Complex E – Enzyme F - Products THERE ARE TWO (2) KINDS OF ENZYME-CONTROLLED REACTIONS: SYNTHESIS (Build up) Makes COMPLEX substances by joining simple ones together HYDROLYSIS (Break down) Sometimes called DIGESTION! Breaks complex molecules into smaller, simple ones SYNTHESIS HYDROLYSIS HYDROLYSIS REACTION VIDEO http://youtu.be/b7TdWLNhMtM