Endocrine System Test 1. In the list of statements below pick the proper definition and example of Endocrine gland. I. II. III. IV. Secrete products (hormones) into ducts which empty into body cavities or body surface Secrete products (hormones) into bloodstream Pituitary, thyroid, parathyroid, adrenal, pineal Sweat, oil, mucous, & digestive glands a. I and III b. I and IV c. II and III d. II and IV Slide #6 2. All of the following are general functions of hormones EXCEPT: a. Metabolism b. All brain activity c. Biological clock d. Growth & development e. Reproduction Slide #7 3. Within the human body we have roughly how many hormone receptors a) b) c) d) 2 000-5 000 2 000-10 000 2000- 100 000 2000- 1 000 000 Slide #11 4. Choose the two descriptions that most correctly define Up-regulation I. II. III. IV. Excess hormone, produces a decrease in number of receptors Receptors undergo endocytosis and are degraded Decreased sensitivity of target cells to hormone Deficiency of hormone, produces an increase in the number of receptors V. Target tissue is more sensitive to the hormone a) b) c) d) I, II and III I and II II, IV, and V IV and V Slide #11 5. Using a) to represent circulating hormones and b) to represent local hormones place the appropriate letter by the description. _a_ act on distant targets _b_ paracrines act on neighboring cells _b_ autocrines act on same cell that secreted them _a_ travel in blood Slide#13 6. When the hormone binds to the cell surface or the receptor inside target cell, the cell may then do all of the following EXCEPT: a) synthesize new molecules b) Activate the construction of new cells c) change permeability of membrane d) alter rates of reactions Slide#18 7. One single molecule of hormone can bind to a receptor and activate: a) b) c) d) 100 G-proteins 1000 G-proteins 10 000 G-proteins millions of G-proteins Slide #25 8. All of the following are true about Cholera Toxin EXCEPT a) It is deadly because it produces massive watery diarrhea and person dies from dehydration b) Toxin of cholera bacteria causes G-protein to lock in activated state in intestinal epithelium c) Intestinal cells actively transport chloride (Na+ and water follow) OUT of the lumen d) Person die unless ions and fluids are replaced & receive antibiotic treatment Slide #26 9. Using a) for Permissive effect, b) for Synergistic effect and c) for Antagonistic effect place the appropriate letter by the statement below: _c_ insulin promotes glycogen formation & glucagon stimulates glycogen breakdown _a_ a second hormone, strengthens the effects of the first _b_ two hormones acting together for greater effect _b_ estrogen & LH are both needed for oocyte production _a_ thyroid strengthens epinephrine’s effect upon lipolysis _c_ two hormones with opposite effects Slide #27 10. Hypothalamus controls the pituitary gland with how many different releasing & inhibiting hormones. a) b) c) d) 5 9 7 15 Slide #33 11. The majority of the pituitary is located in which lobe? a) Anterior b) Posterior Slide #34 12. Name the functional attachment from the pituitary to the brain. a) sella turcica b) pituicytes c) hypothalamus d) Infundibulum 13. A baby drops deep into the uterus stimulating stretch receptors that produce a hormone s which acts on the pituitary to produce oxytocin stimulating uterine contraction and further dropping the baby in the uterus. This is an example of: a) b) c) d) Positive feedback loop Negative feedback loop Hormone hyposecretion Antagonistic hormone effects Slide 27-32 14. Which one of the following four descriptors is correct describing the flow of blood to the anterior pituitary: a. Controlling hormones enter the blood, blood enters the anterior pituitary at the capillaries and finally it travels through the portal veins. b. Controlling hormones enter the blood, they then travel through the portal veins and finally enter anterior pituitary at the capillaries. c. Travel through the portal veins, entering the anterior pituitary at the capillaries and finally the hormones enter the blood. d. None of the above is correct. Slide #35, 36 15. All of the following are correct about human growth hormone EXCEPT: a. Produced by somatotrophs b. common target cells are liver, skeletal muscle, cardiac muscle and striated muscle. c. increases cell growth & cell division by increasing their uptake of amino acids & synthesis of proteins d. stimulate lipolysis in adipose so fatty acids used for ATP (energy) e. retard use of glucose for ATP production so blood glucose levels remain high enough to supply brain Slide #37 16. The regulation of human growth hormone is correct in which of the following examples: a. Low blood sugar stimulates GHIH from hypothalamus and therefore more glycogen is broken down into glucose by liver cells b. High blood suger stimulates GNRH from hypothalamus and therefore less human growth hormone is produced from anterior pituitary resulting in no glycogen breakdown. c. Low blood suger stimulates GNRH from hypothalamus and therefore more human growth hormone is produced from anterior pituitary resulting in no glycogen breakdown. d. None of the above is correct Slide #38, 39 17. Thyroid Stimulating Hormone (TSH) directly regulates which of the following processes: a. b. c. d. Gastrointestinal motility Neural synapse frequency Metabolic rate Liver function Slide #41 18. Follicle Stimulating Hormone (FSH) regulates all of the following EXCEPT: a. b. c. d. conception initiates the formation of follicles within the ovary stimulates follicle cells to secrete estrogen stimulates sperm production in testes Slide #42 19. In females Luteinizing Hormone stimulates (LH) all of the following EXCEPT: a. b. c. d. secretion of estrogen ovulation of 2nd oocyte from ovary formation of corpus luteum stimulates interstitial cells to secrete testosterone Slide #43 20. Which of the following is INCORRECT about Prolactin (PRL) a. Under right conditions, prolactin causes milk production b. Suckling increases levels of hypothalamic inhibition and prolactin levels decrease along with milk production c. Nursing ceases & milk production slows d. All are correct about prolactin Slide #44 21. The posterior pituitary gland secretes which two hormones a. b. c. d. FSH and TSH LH and HGF FSH and HGF Oxytocin and antidiurectic hormone. Slide #47, 48 22. Vasopressin has all of the following functions EXCEPT: a) b) c) d) decrease urine production increases heart rate decrease sweating increase blood pressure Slide #52 23. In dehydration all of the following occur within the body EXCEPT: a) b) c) d) ADH is inhibited Kidneys retain more sodium and water Sudoriferous glands decrease water loss by perspiration from the skin Arterioles constrict to increase blood pressure. Slide #53, 54 24. Which of the following thyroid hormones is responsible for the building of bone: a) b) c) d) Triiodothyronine Thyroxine Calcitonin thyroglobulin Slide #62, 63 25. The parathyroid gland has all of the following functions EXCEPT: a) b) c) d) increase activity of osteoclasts increases reabsorption of calcium by kidney increases reabsorption of phosphate increases absorption of calcium and magnesium by the intestinal tract Slide #68 26. 95% of hormone activity is due to a) b) c) d) Pituitary Hypothalamus Cortisol All of the above Slide #80 27. Name four areas of the body that produce hormones 1. Hypothalamus 2. Adrenals 3. Pituitary 4. Pancreas 28. Match the pancreatic cell with the material that it secretes _d_ alpha cell a. insulin _a_ beta cell b. somatostatin _b_ delta cell c. pancreatic poly peptide _c_ F-cell d. glucagon Slide 84, 85 29. What is the most crucial importance of the thymus gland. a) b) c) d) Responsible for setting the biological clock Regulates glucagon and insulin Responsible for maturation of T cells Responsible for the reabsorption of sodium and chloride Slide #94 30. The Pineal Gland is located in which part of the body. a) b) c) d) Heart Lungs Kidneys Brain Slide #90 Lifecycle nutrition Test questions 31. During pregnancy the daily caloric increase necessary to support a healthy fetus is: a) 100 calories/day b) 300 calories/day c) 500 calories/day d) 600 calories/day Slide #4 32. What is the healthy weight gain during pregnancy: a) b) c) d) 10-20 lbs 25-35lbs 30-40lbs More than 50lbs Slide #6 33. Which of the following special vitamins deficiencies will result in neural tube defects? a) b) c) d) Calcium Iron Folate Potassium Slide #7 34. Match the vitamin with the daily recommended intake for a pregnant female. _d_ Vitamin D _a_ Folate _b_ Calcium _c_ Iron Slide #7, 9 a. b. c. d. 400mcg/day 1200-1500 mg/day 30 mg/day 10 mcg/day 35. Infants daily caloric requirements are: a) b) c) d) 1000 calories/day 2000 calories/day 4000 calories/day 5000 calories/day Slide #12 36. Female weight increases during adolescence can be a) b) c) d) 25lbs 35lbs 45lbs 55lbs Slide #14 37. During adolescence caloric intake for males can be as high as _______ to maintain lean muscle. a) b) c) d) 1000 calories/day 2000 calories/day 4000 calories/day 5000 calories/day Slide #15